LOCUS       NM_001012416             561 bp    mRNA    linear   PRI 27-JUL-2024
DEFINITION  Homo sapiens keratin associated protein 5-6 (KRTAP5-6), mRNA.
ACCESSION   NM_001012416 XM_498505
VERSION     NM_001012416.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 561)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 561)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 561)
  AUTHORS   Chen,S., Fragoza,R., Klei,L., Liu,Y., Wang,J., Roeder,K., Devlin,B.
            and Yu,H.
  TITLE     An interactome perturbation framework prioritizes damaging missense
            mutations for developmental disorders
  JOURNAL   Nat Genet 50 (7), 1032-1040 (2018)
   PUBMED   29892012
REFERENCE   4  (bases 1 to 561)
  AUTHORS   Yahagi,S., Shibuya,K., Obayashi,I., Masaki,H., Kurata,Y., Kudoh,J.
            and Shimizu,N.
  TITLE     Identification of two novel clusters of ultrahigh-sulfur
            keratin-associated protein genes on human chromosome 11
  JOURNAL   Biochem Biophys Res Commun 318 (3), 655-664 (2004)
   PUBMED   15144888
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AB126075.1.
            
            On Feb 23, 2005 this sequence version replaced XM_498505.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AB126075.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000382160.1/ ENSP00000371595.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..561
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.5"
     gene            1..561
                     /gene="KRTAP5-6"
                     /gene_synonym="KRTAP5.6"
                     /note="keratin associated protein 5-6"
                     /db_xref="GeneID:440023"
                     /db_xref="HGNC:HGNC:23600"
     exon            1..561
                     /gene="KRTAP5-6"
                     /gene_synonym="KRTAP5.6"
                     /inference="alignment:Splign:2.1.0"
     CDS             52..441
                     /gene="KRTAP5-6"
                     /gene_synonym="KRTAP5.6"
                     /note="keratin-associated protein 5.6; ultrahigh sulfur
                     keratin-associated protein 5.6"
                     /codon_start=1
                     /product="keratin-associated protein 5-6"
                     /protein_id="NP_001012416.1"
                     /db_xref="CCDS:CCDS31332.1"
                     /db_xref="GeneID:440023"
                     /db_xref="HGNC:HGNC:23600"
                     /translation="MGCCGCSGGCGSGCGGCGSGCGGCGSSCCVPICCCKPVCCCVPA
                     CSCTSCGSCGGSKGCCGSCGGSKGGCGSCGGSKGGCGSCGCSQCSCCKPCYCSSGCGS
                     SCCQSSCCKPCCSQASCCVPICCQCKI"
ORIGIN      
        1 cctccctctc acctgctcct ctacctgctc caccctcaat ccaccagaac catgggctgc
       61 tgtggctgct ctggaggctg tggctccggc tgtgggggct gtggctctgg ctgtgggggc
      121 tgtgggtcca gctgctgtgt gcccatctgc tgctgcaagc ccgtgtgctg ctgtgtgcca
      181 gcctgttcct gcaccagctg tggctcttgt gggggctcca aggggtgctg tggctcttgt
      241 gggggctcca aagggggctg tggctcttgt gggggctcca agggaggctg tggctcttgt
      301 ggctgctccc agtgcagttg ctgcaagccc tgctactgtt cctcaggctg tgggtcatcc
      361 tgctgccagt ccagctgctg caagccctgc tgttcccagg ccagctgctg tgtccccatt
      421 tgctgccagt gcaaaatctg aggctctgac tttggacctc aggtgagtcc agcatatcca
      481 caccacccaa gaagtgacca gtgctgcatt tcagttctgg ctgtcccaca gctccaggag
      541 ttgtgtcccc tgaattttgc a
//
