LOCUS       NM_001347674            1181 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens keratin associated protein 5-4 (KRTAP5-4), transcript
            variant 1, mRNA.
ACCESSION   NM_001347674
VERSION     NM_001347674.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1181)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1181)
  AUTHORS   Yahagi,S., Shibuya,K., Obayashi,I., Masaki,H., Kurata,Y., Kudoh,J.
            and Shimizu,N.
  TITLE     Identification of two novel clusters of ultrahigh-sulfur
            keratin-associated protein genes on human chromosome 11
  JOURNAL   Biochem Biophys Res Commun 318 (3), 655-664 (2004)
   PUBMED   15144888
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP006285.2.
            
            Transcript Variant: This variant (1) represents the allele present
            in the GRCh38 primary assembly. It encodes isoform 1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on the transcript AB126073.1.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000399682.1/ ENSP00000382590.1
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1181              AP006285.2         116370-117550       c
FEATURES             Location/Qualifiers
     source          1..1181
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.5"
     gene            1..1181
                     /gene="KRTAP5-4"
                     /gene_synonym="KRTAP5.4"
                     /note="keratin associated protein 5-4"
                     /db_xref="GeneID:387267"
                     /db_xref="HGNC:HGNC:23599"
     exon            1..1181
                     /gene="KRTAP5-4"
                     /gene_synonym="KRTAP5.4"
                     /inference="alignment:Splign:2.1.0"
     CDS             46..732
                     /gene="KRTAP5-4"
                     /gene_synonym="KRTAP5.4"
                     /note="isoform 1 is encoded by transcript variant 1;
                     keratin-associated protein 5.4; ultrahigh sulfur
                     keratin-associated protein 5.4"
                     /codon_start=1
                     /product="keratin-associated protein 5-4 isoform 1"
                     /protein_id="NP_001334603.1"
                     /db_xref="CCDS:CCDS86161.1"
                     /db_xref="GeneID:387267"
                     /db_xref="HGNC:HGNC:23599"
                     /translation="MGCCGCSGGCGSGCGGCGSGCGGCGSGCGGCGSGCGGCGSGCGG
                     CGSSCCVPICCCKPVCCCVPACSCSSCGSCGGSKGGYGSCGGSKGGCVSCGGSKGGCG
                     SCGGSKGGCGSCGGSKGGCGSCGGSKGGCGSCGCSQCSCCKPCCFSSGCGSSCCQSSC
                     CKPCCSSSGCGSSCCQSSCCKPYCCQSSCCKPCCSSSGCGSSCCQSSCCNPCCSQSSC
                     CVPVCCQCKI"
ORIGIN      
        1 tctcatctgc tcctctacct gctccaccct caatccacca gaaccatggg ctgctgtggc
       61 tgctctggag gctgtggctc cggctgtggg ggctgtggct ccggctgtgg gggctgtggc
      121 tctggctgtg ggggctgtgg ctccggctgt gggggctgtg gctccggctg tgggggctgt
      181 ggctccagct gctgtgtgcc catctgctgc tgcaaacctg tgtgctgctg tgtgccagcc
      241 tgttcctgct ccagctgtgg ctcctgtggg ggctccaagg ggggctatgg ctcttgtggg
      301 ggttccaagg ggggctgtgt ctcctgtggg ggttccaagg ggggctgtgg ctcctgtggg
      361 ggctccaagg ggggctgtgg ctcctgtggg ggttccaagg ggggctgtgg ctcctgtggg
      421 ggctccaaag gaggctgtgg ctcttgtggc tgctcccagt gcagctgctg taagccctgc
      481 tgcttctctt caggctgtgg gtcatcctgc tgccagtcca gctgctgtaa gccctgctgc
      541 tcctcctcag gttgtgggtc atcctgctgc cagtccagct gctgcaagcc ctactgctgc
      601 cagtccagct gctgtaagcc ctgctgctcc tcctcaggtt gtgggtcatc ctgctgccag
      661 tccagttgct gcaatccctg ctgctcccag tctagttgct gtgtccctgt gtgctgccag
      721 tgtaagatct gaggctctgg actcaggcct catgtgagtc ctgctaatcc tgtcttccaa
      781 agctgtgacc tgtccttcat tgttgagccc caaatcattg ctcagggtcc attccctgct
      841 gtagaacgat gccatatctg gctgcctttt cctaagaaga gtccacccta attaatgtcc
      901 attgtctctc ctaacaaatt ctctccccaa gtcaactgca attgcagctg aatcacccct
      961 cacccactag cctcgccttt gctcatcttt tcagaggcct gagctcctga acccacttgc
     1021 agtcctgtct tttccagctg gagcagctgg gcataagcgt cccacctgca acaaggtggg
     1081 cgtttaagag gcttccttgg agtggctttg catgtccaac actctgctgt atcttttttt
     1141 tttttttttt ttttttgaga tggagtctcg cactgtcacc c
//
