LOCUS       NM_001004325            1118 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens keratin associated protein 5-2 (KRTAP5-2), mRNA.
ACCESSION   NM_001004325 XM_498503
VERSION     NM_001004325.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1118)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1118)
  AUTHORS   Clarke,L.E., Conway,A.B., Warner,N.M., Barnwell,P.N., Sceppa,J. and
            Helm,K.F.
  TITLE     Expression of CK7, Cam 5.2 and Ber-Ep4 in cutaneous squamous cell
            carcinoma
  JOURNAL   J Cutan Pathol 40 (7), 646-650 (2013)
   PUBMED   23590728
  REMARK    GeneRIF: CK7 and Cam 5.2 expression may occur in SCC. A panel
            including Ber-Ep4 is advisable for immunohistochemical
            differentiation of EPD from SCC.
REFERENCE   3  (bases 1 to 1118)
  AUTHORS   Yahagi,S., Shibuya,K., Obayashi,I., Masaki,H., Kurata,Y., Kudoh,J.
            and Shimizu,N.
  TITLE     Identification of two novel clusters of ultrahigh-sulfur
            keratin-associated protein genes on human chromosome 11
  JOURNAL   Biochem Biophys Res Commun 318 (3), 655-664 (2004)
   PUBMED   15144888
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AJ628245.1.
            
            On May 17, 2019 this sequence version replaced NM_001004325.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AJ628245.1, BC132908.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000412090.2/ ENSP00000400041.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1118              AJ628245.1         1-1118
FEATURES             Location/Qualifiers
     source          1..1118
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.5"
     gene            1..1118
                     /gene="KRTAP5-2"
                     /gene_synonym="KRTAP5-8; KRTAP5.2"
                     /note="keratin associated protein 5-2"
                     /db_xref="GeneID:440021"
                     /db_xref="HGNC:HGNC:23597"
     exon            1..1118
                     /gene="KRTAP5-2"
                     /gene_synonym="KRTAP5-8; KRTAP5.2"
                     /inference="alignment:Splign:2.1.0"
     CDS             45..578
                     /gene="KRTAP5-2"
                     /gene_synonym="KRTAP5-8; KRTAP5.2"
                     /note="keratin-associated protein 5-8; keratin-associated
                     protein 5.2; keratin-associated protein 5.8; ultrahigh
                     sulfur keratin-associated protein 5.2"
                     /codon_start=1
                     /product="keratin-associated protein 5-2"
                     /protein_id="NP_001004325.1"
                     /db_xref="CCDS:CCDS31331.1"
                     /db_xref="GeneID:440021"
                     /db_xref="HGNC:HGNC:23597"
                     /translation="MGCCGCSRGCGSGCGGCGSSCGGCGSGCGGCGSGRGGCGSGCGG
                     CSSSCGGCGSRCYVPVCCCKPVCSWVPACSCTSCGSCGGSKGGCGSCGGSKGGCGSCG
                     GSKGGCGSCGCSQSSCCKPCCCSSGCGSSCCQSSCCKPCCCQSSCCVPVCCQSSCCKP
                     CCCQSNCCVPVCCQCKI"
ORIGIN      
        1 ctcacctgct cctctacctg ctccaccctc aatccaccag aaccatgggc tgctgtggct
       61 gctccagagg ctgtggctcc ggctgtgggg gctgtggctc cagctgtggg ggttgtggct
      121 ctggctgtgg gggctgtggc tccggccgtg ggggctgtgg ctctggctgt gggggctgca
      181 gctccagctg tgggggatgt ggctccagat gttatgtgcc tgtctgctgc tgcaagcccg
      241 tgtgctcctg ggtgccagcc tgttcctgca ccagctgtgg ctcctgtggg ggctccaagg
      301 ggggctgtgg ctcctgtggg ggctccaagg ggggctgtgg ctcctgtggg ggttccaagg
      361 ggggctgtgg ttcttgtggc tgctcccagt ccagctgttg taagccctgt tgctgctcct
      421 caggctgtgg atcatcctgc tgccagtcca gctgctgcaa gccctgctgc tgccagtcca
      481 gctgctgtgt ccccgtgtgc tgccagtcca gctgctgcaa gccctgttgc tgccagtcca
      541 actgttgtgt ccctgtgtgc tgccagtgta agatctgagg ctctggaccc agaccttcag
      601 gtttctcctg tttggtgaaa gcatttctta tggttccctg agtcagttcg tcccacacat
      661 cctccctgag gcacctgcac ctgctctagc tcaccatcca tgcacacacc tccttccatg
      721 gctcagctct cctctgggcc ctgccttcag cctcctcact ccagaaacgt gtgtttccct
      781 gatgcgggag gtgtcctcgc ctggacgcag gcacccagcc gactgccacg atgttccctg
      841 cacttgggtg tggaccatct tcttcttctc cctgggctga ctgagatgca aggtctgacc
      901 ccacaaggcc aggccgacgt ttctgagtga tcactaagaa ccagcttctc aaccaccatc
      961 aggaccctgg atcctcctgg gccgctgcct gttctcctgt ggcccaagtg tgaccaggaa
     1021 ggtctctttc cttcctgttg tctccatctg tttaaaaaaa aataacaaaa taatgaatga
     1081 atttccttgc aataaagcct ctcatgtctg taaatcaa
//
