LOCUS       NM_001005922             942 bp    mRNA    linear   PRI 02-JUN-2024
DEFINITION  Homo sapiens keratin associated protein 5-1 (KRTAP5-1), mRNA.
ACCESSION   NM_001005922
VERSION     NM_001005922.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 942)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 942)
  AUTHORS   Soma,T., Ishimatsu-Tsuji,Y., Tajima,M. and Kishimoto,J.
  TITLE     Runx1 transcription factor is involved in the regulation of KAP5
            gene expression in human hair follicles
  JOURNAL   J Dermatol Sci 41 (3), 221-224 (2006)
   PUBMED   16442267
  REMARK    GeneRIF: KAP5 gene expression in human hair follicles is regulated
            by Runx1
REFERENCE   3  (bases 1 to 942)
  AUTHORS   Yahagi,S., Shibuya,K., Obayashi,I., Masaki,H., Kurata,Y., Kudoh,J.
            and Shimizu,N.
  TITLE     Identification of two novel clusters of ultrahigh-sulfur
            keratin-associated protein genes on human chromosome 11
  JOURNAL   Biochem Biophys Res Commun 318 (3), 655-664 (2004)
   PUBMED   15144888
REFERENCE   4  (bases 1 to 942)
  AUTHORS   Sun,X.K., Ma,L.L., Xie,Y.Q. and Zhu,X.J.
  TITLE     Keratin 1 and keratin 10 mutations causing epidermolytic
            hyperkeratosis in Chinese patients
  JOURNAL   J Dermatol Sci 29 (3), 195-200 (2002)
   PUBMED   12234709
  REMARK    GeneRIF: A novel mutation designated as E477K of K1 was identified
            in epidermolytic hyperkeratosis.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AB126070.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AB126070.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000382171.2/ ENSP00000371606.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..942
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.5"
     gene            1..942
                     /gene="KRTAP5-1"
                     /gene_synonym="KRN1L; KRTAP5.1"
                     /note="keratin associated protein 5-1"
                     /db_xref="GeneID:387264"
                     /db_xref="HGNC:HGNC:23596"
                     /db_xref="MIM:148022"
     exon            1..942
                     /gene="KRTAP5-1"
                     /gene_synonym="KRN1L; KRTAP5.1"
                     /inference="alignment:Splign:2.1.0"
     CDS             35..871
                     /gene="KRTAP5-1"
                     /gene_synonym="KRN1L; KRTAP5.1"
                     /note="keratin-associated protein 5.1; ultrahigh sulfur
                     keratin-associated protein 5.1"
                     /codon_start=1
                     /product="keratin-associated protein 5-1"
                     /protein_id="NP_001005922.1"
                     /db_xref="CCDS:CCDS31330.1"
                     /db_xref="GeneID:387264"
                     /db_xref="HGNC:HGNC:23596"
                     /db_xref="MIM:148022"
                     /translation="MGCCGCSGGCGSSCGGCGSGCGGCGSGCGGCGSGCGGSGSSCCV
                     PVCCCKPVCCRVPTCSCSSCGKGGCGSSGGSKGGCGSCGGCKGGCGSCGGSKGGCGSC
                     GGSKGGCGSCGGSKGGCGSGCGGCGSSCCVPVCCCKPMCCCVPACSCSSCGKGGCGSC
                     GCSKGACGSCGGSKGGCGSCGGCKGGCGSCGGSKGGCGSGCGGCGSGCGVPVCCCSCS
                     SCGSCAGSKGGCGSSCSQCSCCKPCCCSSGCGSSCCQSSCCKPCCSQSSCCVPVCCQC
                     KI"
ORIGIN      
        1 cctctacctg ctccaccctc aatccaccag aaccatgggc tgttgcggct gctccggagg
       61 ctgtggctcc agctgtgggg gctgtggctc cggctgtggg ggctgtggct ccggctgtgg
      121 gggctgtggc tctggctgtg gaggttctgg ctccagctgc tgtgtgcccg tctgctgctg
      181 caagcccgtg tgctgccgtg tgccaacctg ttcctgctcc agctgtggca aagggggctg
      241 tggctcttct gggggctcca aggggggctg tggctcctgt ggaggctgca aggggggctg
      301 tggctcttgt gggggatcca aggggggttg tggctcctgt gggggctcca aggggggctg
      361 tggctcttgt gggggatcca agggtggctg tggttccggc tgtgggggat gtggctccag
      421 ctgctgtgtg cctgtctgct gctgcaagcc catgtgctgc tgtgtgccag cttgttcctg
      481 ctccagctgt ggcaaagggg gctgtggctc ctgtgggtgc tccaaggggg cctgtggttc
      541 ttgtgggggc tccaaggggg gctgtggctc ctgtggaggc tgcaaggggg gctgcggttc
      601 ttgtggggga tccaaggggg gttgtggctc cggctgtggg ggctgtggct ccggctgcgg
      661 tgtgcccgtg tgttgctgtt cctgttccag ttgtggctct tgcgcggggt ctaagggagg
      721 ctgcgggtca tcctgctccc agtgcagttg ctgtaagccc tgctgctgtt cctcaggctg
      781 tgggtcatcc tgttgccaat ccagctgctg caagccctgc tgctcccagt ccagttgctg
      841 tgtccccgtg tgctgccagt gcaagatctg atttctggct ttgcaggact cttaccatgg
      901 ccaggcattc ctgcccagcc tttacctcct tttcctggca cc
//
