LOCUS       NM_030976               1112 bp    mRNA    linear   PRI 17-FEB-2024
DEFINITION  Homo sapiens keratin associated protein 4-6 (KRTAP4-6), mRNA.
ACCESSION   NM_030976 XM_003118737
VERSION     NM_030976.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1112)
  AUTHORS   Kariya,N., Shimomura,Y. and Ito,M.
  TITLE     Size polymorphisms in the human ultrahigh sulfur hair
            keratin-associated protein 4, KAP4, gene family
  JOURNAL   J Invest Dermatol 124 (6), 1111-1118 (2005)
   PUBMED   15955084
REFERENCE   2  (bases 1 to 1112)
  AUTHORS   Rogers,M.A., Langbein,L., Winter,H., Ehmann,C., Praetzel,S.,
            Korn,B. and Schweizer,J.
  TITLE     Characterization of a cluster of human high/ultrahigh sulfur
            keratin-associated protein genes embedded in the type I keratin
            gene domain on chromosome 17q12-21
  JOURNAL   J Biol Chem 276 (22), 19440-19451 (2001)
   PUBMED   11279113
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC100808.10.
            
            On Aug 11, 2021 this sequence version replaced NM_030976.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AJ406945.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000345847.5/ ENSP00000328270.5
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1112              AC100808.10        21037-22148
FEATURES             Location/Qualifiers
     source          1..1112
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q21.2"
     gene            1..1112
                     /gene="KRTAP4-6"
                     /gene_synonym="KAP4.15; KAP4.6; KRTAP4-15; KRTAP4.15"
                     /note="keratin associated protein 4-6"
                     /db_xref="GeneID:81871"
                     /db_xref="HGNC:HGNC:18909"
     exon            1..1112
                     /gene="KRTAP4-6"
                     /gene_synonym="KAP4.15; KAP4.6; KRTAP4-15; KRTAP4.15"
                     /inference="alignment:Splign:2.1.0"
     CDS             58..675
                     /gene="KRTAP4-6"
                     /gene_synonym="KAP4.15; KAP4.6; KRTAP4-15; KRTAP4.15"
                     /note="keratin associated protein 4-15; keratin-associated
                     protein 4.6; ultrahigh sulfur keratin-associated protein
                     4.15"
                     /codon_start=1
                     /product="keratin-associated protein 4-6"
                     /protein_id="NP_112238.1"
                     /db_xref="CCDS:CCDS54125.1"
                     /db_xref="GeneID:81871"
                     /db_xref="HGNC:HGNC:18909"
                     /translation="MVSSCCGSVCSDQGCGLETCCRPSCCQTTCCRTTCCRPSCCVSS
                     CCRPQCCQSVCCQPTCCRPSCCPSCCQTTCCRTTCCRPSCCVSSCCRPQCCQSVCCQP
                     TCCRPSCSISSCCRPSCCVSRCCRSQCCQSVCCQPTCCRPSCCISSCCRPSCCESSCC
                     RPCCCRPCCCLRPVCGRVSCHTTCYRPTCVISTCPRPLCCASSCC"
ORIGIN      
        1 aaactcacga aactcactct cttggaaacc cacccagaac ctttaccctc tgacaccatg
       61 gtcagctcct gttgtggttc cgtctgctct gaccagggct gtggcctgga gacctgctgc
      121 cgccccagct gctgtcagac cacctgctgc aggaccacct gctgccgccc cagctgctgt
      181 gtgtccagct gctgcagacc ccagtgctgc cagtctgtgt gctgccagcc cacctgctgc
      241 cgtcccagct gctgtcccag ctgctgtcag accacctgct gcaggaccac ctgctgccgc
      301 cctagctgct gtgtatccag ctgctgcaga ccccagtgct gccagtctgt gtgctgccag
      361 cccacttgct gccgtcccag ctgcagcatc tccagctgct gtcgccccag ctgctgtgtg
      421 tccaggtgct gcaggtccca gtgctgccag tctgtgtgct gccagccaac ctgctgccgt
      481 cccagctgct gcatctccag ctgctgccgc ccctcttgct gtgaatccag ctgctgccgc
      541 ccgtgctgct gccgcccctg ctgctgcctg cgtccagtct gtggccgagt ctcctgccac
      601 accacttgct atcgcccaac ctgtgtcatt tccacctgcc cccgtccctt gtgctgtgcc
      661 tcctcttgct gctgagctcc ttgcctgaaa ctatctcctc cccttcagct cactcctcac
      721 agaagcagac cttgtgcatc tcataaacaa ctcagaagag gccattccca ccaactgtgt
      781 ttccatatcc tggacatata tctaggatat atgtcctggc tatacatcta gaatatatgt
      841 tccccatgtt gacccaagtg tgaaattaga tattatttac agaaagaaat taatagaatt
      901 taccaaattt tataccttat atttgtattt atggatacca agttcttctg tcccaaacat
      961 ggaaattctt gcagggtaac tcggggcaag gttgtctcac tctcagattt gaaagtctga
     1021 ttgtttcacc ctgtatttcc ttttacagca atgtttctgt atcttatttt tgctgcttct
     1081 gaataaaact ccacttttgt cgcatagaaa ta
//
