LOCUS       NM_033187                991 bp    mRNA    linear   PRI 10-FEB-2024
DEFINITION  Homo sapiens keratin associated protein 4-3 (KRTAP4-3), mRNA.
ACCESSION   NM_033187 XM_497545 XM_937175
VERSION     NM_033187.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 991)
  AUTHORS   Choi,H.I., Choi,G.I., Kim,E.K., Choi,Y.J., Sohn,K.C., Lee,Y.,
            Kim,C.D., Yoon,T.J., Sohn,H.J., Han,S.H., Kim,S., Lee,J.H. and
            Lee,Y.H.
  TITLE     Hair greying is associated with active hair growth
  JOURNAL   Br J Dermatol 165 (6), 1183-1189 (2011)
   PUBMED   21916889
REFERENCE   2  (bases 1 to 991)
  AUTHORS   Kariya,N., Shimomura,Y. and Ito,M.
  TITLE     Size polymorphisms in the human ultrahigh sulfur hair
            keratin-associated protein 4, KAP4, gene family
  JOURNAL   J Invest Dermatol 124 (6), 1111-1118 (2005)
   PUBMED   15955084
REFERENCE   3  (bases 1 to 991)
  AUTHORS   Rogers,M.A., Langbein,L., Winter,H., Ehmann,C., Praetzel,S.,
            Korn,B. and Schweizer,J.
  TITLE     Characterization of a cluster of human high/ultrahigh sulfur
            keratin-associated protein genes embedded in the type I keratin
            gene domain on chromosome 17q12-21
  JOURNAL   J Biol Chem 276 (22), 19440-19451 (2001)
   PUBMED   11279113
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC006070.1 and AJ406935.1.
            
            On May 17, 2019 this sequence version replaced NM_033187.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000391356.4/ ENSP00000375151.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-49                AC006070.1         138889-138937
            50-340              AC006070.1         138938-139228
            341-991             AJ406935.1         1-651
FEATURES             Location/Qualifiers
     source          1..991
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q21.2"
     gene            1..991
                     /gene="KRTAP4-3"
                     /gene_synonym="KAP4.3"
                     /note="keratin associated protein 4-3"
                     /db_xref="GeneID:85290"
                     /db_xref="HGNC:HGNC:18908"
     exon            1..991
                     /gene="KRTAP4-3"
                     /gene_synonym="KAP4.3"
                     /inference="alignment:Splign:2.1.0"
     CDS             50..637
                     /gene="KRTAP4-3"
                     /gene_synonym="KAP4.3"
                     /note="keratin-associated protein 4.3; ultrahigh sulfur
                     keratin-associated protein 4.3"
                     /codon_start=1
                     /product="keratin-associated protein 4-3"
                     /protein_id="NP_149443.1"
                     /db_xref="CCDS:CCDS42331.1"
                     /db_xref="GeneID:85290"
                     /db_xref="HGNC:HGNC:18908"
                     /translation="MVSSCCGSVCSDQSCGQGLGQESCCRPSCCQTTCCRTTCCRPSC
                     CISSCCRPSCCISSCCKPSCCRTTCCRPSCCISSCCRPSCCISSCCKPSCCRTTCCRP
                     SCCISSCCRPSCCISSCCKPSCCQTTCCRPSCCISSCYRPQCCQPSCCRPACCISSCC
                     HPSCCVSSCRCPFSCPTTCCRTTCFHPICCGSSCC"
ORIGIN      
        1 gaacctcatt ctcctgggaa cccacccaga acctccaccc tctgacgcca tggtcagctc
       61 ctgctgtggc tctgtctgct ctgaccagag ctgtggtcaa ggtctcggcc aggagagctg
      121 ctgccgcccc agctgctgcc agaccacctg ctgcaggacc acctgctgcc gccccagctg
      181 ctgcatttcc agttgctgca ggccttcctg ctgtatctcc agctgctgca aacccagctg
      241 ctgcaggacc acctgctgcc gccccagctg ctgcatttcc agttgctgca ggccttcctg
      301 ctgtatctcc agctgctgca aacccagctg ctgcaggacc acctgctgcc gccccagctg
      361 ctgcatttct agttgctgca ggccttcctg ctgtatctct agctgttgca aacccagctg
      421 ctgccagacc acctgctgcc gccccagctg ctgtatctcc agctgctaca ggccccagtg
      481 ctgccagccc tcctgctgcc gcccggcttg ctgcatttct agttgctgtc atcccagctg
      541 ctgtgtgtcc agctgccgct gccctttcag ctgcccgacc acctgctgta gaacaacctg
      601 cttccacccc atctgctgcg gcagttcttg ctgctgagtg aagctgctct ggatttgtgc
      661 accttcttgc tctcaacctt cagttcaggc acagagtatc tattcagaga acatgtggac
      721 ttcctgatgt cgtgaaaaca gaggcatgga ctgatttgga aaatatttta ttagtatgta
      781 ttctctttta tagaagtttt tattcctatt gaatctgaat ttacagtcaa attccacatc
      841 acatgtttta gaattcttta ttctaattca atatacataa atcttcaaat ggtatccttc
      901 tagatgtttc ttcctaatgt tttctgtggt atcaattttc atgtggaatt gtttgatgtt
      961 cctcaataaa acttcatagt gttcaaaagc a
//
