LOCUS       NM_033059               1193 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens keratin associated protein 4-11 (KRTAP4-11), mRNA.
ACCESSION   NM_033059 XM_926590
VERSION     NM_033059.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1193)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1193)
  AUTHORS   Sakai,Y., Shaw,C.A., Dawson,B.C., Dugas,D.V., Al-Mohtaseb,Z.,
            Hill,D.E. and Zoghbi,H.Y.
  TITLE     Protein interactome reveals converging molecular pathways among
            autism disorders
  JOURNAL   Sci Transl Med 3 (86), 86ra49 (2011)
   PUBMED   21653829
REFERENCE   3  (bases 1 to 1193)
  AUTHORS   Kariya,N., Shimomura,Y. and Ito,M.
  TITLE     Size polymorphisms in the human ultrahigh sulfur hair
            keratin-associated protein 4, KAP4, gene family
  JOURNAL   J Invest Dermatol 124 (6), 1111-1118 (2005)
   PUBMED   15955084
REFERENCE   4  (bases 1 to 1193)
  AUTHORS   Rogers,M.A., Langbein,L., Winter,H., Ehmann,C., Praetzel,S.,
            Korn,B. and Schweizer,J.
  TITLE     Characterization of a cluster of human high/ultrahigh sulfur
            keratin-associated protein genes embedded in the type I keratin
            gene domain on chromosome 17q12-21
  JOURNAL   J Biol Chem 276 (22), 19440-19451 (2001)
   PUBMED   11279113
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff in
            collaboration with Michael Rogers. The reference sequence was
            derived from AC100808.10.
            
            On May 17, 2019 this sequence version replaced NM_033059.3.
            
            Summary: This protein is a member of the keratin-associated protein
            (KAP) family. The KAP proteins form a matrix of keratin
            intermediate filaments which contribute to the structure of hair
            fibers. KAP family members appear to have unique, family-specific
            amino- and carboxyl-terminal regions and are subdivided into three
            multi-gene families according to amino acid composition: the high
            sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs.
            This protein is a member of the ultrahigh sulfur KAP family and the
            gene is localized to a cluster of KAPs at 17q12-q21. [provided by
            RefSeq, Mar 2009].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AJ406944.1, BC130562.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000391413.4/ ENSP00000375232.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1193              AC100808.10        43208-44400
FEATURES             Location/Qualifiers
     source          1..1193
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q21.2"
     gene            1..1193
                     /gene="KRTAP4-11"
                     /gene_synonym="KAP4.11; KAP4.14; KRTAP4-14; KRTAP4.14"
                     /note="keratin associated protein 4-11"
                     /db_xref="GeneID:653240"
                     /db_xref="HGNC:HGNC:18911"
     exon            1..1193
                     /gene="KRTAP4-11"
                     /gene_synonym="KAP4.11; KAP4.14; KRTAP4-14; KRTAP4.14"
                     /inference="alignment:Splign:2.1.0"
     CDS             59..646
                     /gene="KRTAP4-11"
                     /gene_synonym="KAP4.11; KAP4.14; KRTAP4-14; KRTAP4.14"
                     /note="ultrahigh sulfur keratin-associated protein 4.14;
                     keratin-associated protein 4-14; keratin-associated
                     protein 4.11"
                     /codon_start=1
                     /product="keratin-associated protein 4-11"
                     /protein_id="NP_149048.2"
                     /db_xref="CCDS:CCDS45675.1"
                     /db_xref="GeneID:653240"
                     /db_xref="HGNC:HGNC:18911"
                     /translation="MVNSCCGSVCSHQGCGRDLCQETCCRPSCCETTCCRTTYCRPSC
                     CVSSCCRPQCCQSVCCQPTCCRPRCCISSCCRPSCCVSSCCKPQCCQSMCCQPTCCRP
                     RCCISSCCRPSCCVSSCCRPQCCQSVCCQPTCCHPSCSISSCCRPSCCESSCCRPCCC
                     LRPVCGRVSCHTTCYRPTCVISSCPRPLCCASSCC"
ORIGIN      
        1 caaacacaag aacttcactc tcctagaaac ccaactagat ccttcaccct ctgacaccat
       61 ggtaaactcc tgttgtggct ccgtgtgctc tcaccaaggc tgtggccgag acctctgcca
      121 ggagacctgc tgccgcccca gctgctgtga gaccacctgc tgcaggacca cctactgtcg
      181 ccccagctgc tgtgtgtcca gctgctgcag gccccagtgc tgccagtctg tgtgctgcca
      241 gcccacctgc tgccgcccca gatgctgcat ctccagctgc tgtcgcccca gctgctgtgt
      301 gtccagctgc tgcaagcccc agtgctgcca gtctatgtgc tgccagccca cttgctgccg
      361 ccccagatgc tgcatctcca gctgctgtcg ccccagctgc tgtgtgtcca gctgctgcag
      421 accccagtgc tgccagtctg tgtgctgcca gcccacctgc tgccacccca gctgcagcat
      481 ctccagctgc tgccgcccct cttgctgtga atccagctgc tgccgcccct gctgctgcct
      541 gcgtccagtc tgtggccgag tctcctgcca caccacttgc tatcgcccaa cctgtgtcat
      601 ctccagctgc ccccgcccct tgtgctgtgc ctcctcttgc tgctgagccc actgccctgg
      661 ctcatctctc ccttcactgc aggcccacag ttgtagacca ttcttctgtg ctgactatta
      721 ggacacatgg agtgggattg atgtcattca gcagggtgga cttcatgttt ccaatgagcc
      781 catcaccatc ccactgactc tgtgagaaca ttctggttca ttttaaactc cctcccttgc
      841 tttctttctc ttccagtcat ggcaccaaat atgaaataat ttgtaatcca ctagctaaga
      901 aattattcca atcctctaaa ttcctcattt tttaaatcgt tttgagccta cagaatatcc
      961 ttcccagtga ggtacacatt atctccattt caaacatatt atttgtctgt cagcctttca
     1021 gtcattcttt tctcttggaa aggtaggagg ctgcccctcc catgctctcc tgctttctcc
     1081 ctgttctctc tttgtctctg tttgttcaag tttgccagaa tttttctatt ttattggttc
     1141 tttatcttta ttgtgttcac aaaatatatt gtattaaact tttcatttag aaa
//
