LOCUS       NM_001085455            1642 bp    mRNA    linear   PRI 10-FEB-2024
DEFINITION  Homo sapiens keratin associated protein 24-1 (KRTAP24-1), mRNA.
ACCESSION   NM_001085455 XM_001127538 XM_001133542
VERSION     NM_001085455.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1642)
  AUTHORS   Rogers,M.A., Winter,H., Langbein,L., Wollschlager,A.,
            Praetzel-Wunder,S., Jave-Suarez,L.F. and Schweizer,J.
  TITLE     Characterization of human KAP24.1, a cuticular hair
            keratin-associated protein with unusual amino-acid composition and
            repeat structure
  JOURNAL   J Invest Dermatol 127 (5), 1197-1204 (2007)
   PUBMED   17235325
  REMARK    GeneRIF: In situ hybridization and indirect immunofluorescence
            microscopy studies using an antibody derived from KAP24.1
            demonstrated specific expression in the middle/upper hair cuticle.
REFERENCE   2  (bases 1 to 1642)
  AUTHORS   Rogers,M.A., Langbein,L., Praetzel-Wunder,S., Winter,H. and
            Schweizer,J.
  TITLE     Human hair keratin-associated proteins (KAPs)
  JOURNAL   Int Rev Cytol 251, 209-263 (2006)
   PUBMED   16939781
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AB096935.1, KF457192.1, AM238513.1 and AP000884.1.
            
            On May 17, 2019 this sequence version replaced NM_001085455.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AM238513.1, AB096935.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000340345.6/ ENSP00000339238.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-56                AB096935.1         9-64
            57-57               KF457192.1         132-132             c
            58-1612             AM238513.1         40-1594
            1613-1613           AP000884.1         123674-123674       c
            1614-1642           AM238513.1         1596-1624
FEATURES             Location/Qualifiers
     source          1..1642
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="21"
                     /map="21q22.11"
     gene            1..1642
                     /gene="KRTAP24-1"
                     /gene_synonym="KAP24.1"
                     /note="keratin associated protein 24-1"
                     /db_xref="GeneID:643803"
                     /db_xref="HGNC:HGNC:33902"
                     /db_xref="MIM:618927"
     exon            1..1642
                     /gene="KRTAP24-1"
                     /gene_synonym="KAP24.1"
                     /inference="alignment:Splign:2.1.0"
     CDS             19..783
                     /gene="KRTAP24-1"
                     /gene_synonym="KAP24.1"
                     /codon_start=1
                     /product="keratin-associated protein 24-1"
                     /protein_id="NP_001078924.1"
                     /db_xref="CCDS:CCDS42915.1"
                     /db_xref="GeneID:643803"
                     /db_xref="HGNC:HGNC:33902"
                     /db_xref="MIM:618927"
                     /translation="MPAGSMSTTGYPGVCSTTSYRTHCYIPVTSSVTLSSSDLSPTFG
                     HCLPSSYQGNLWLLDYCQESYGEAPTCKSPSCEPKTCSTTGCDPSNSSVPCNSPSAGQ
                     VFSVCETTNVSPSPSCSPSTQTNGYVCNCHIPTRNASKACQTLRNGSNCFGQLNCLSK
                     SFQTLNHCRLSTLGYKSYQNPCFIPSYVSPLCYISNSCQPQSYLVRNYHYSSYRPTSC
                     RPLSYLSRSFRSLSYIPSTFPPLRYLCSGSRPLKCY"
ORIGIN      
        1 gcacagcgac cactgagcat gcctgcaggc tccatgtcta ctacaggcta tcctggggtc
       61 tgcagtacca catcatacag aactcactgt tatatcccag tgacctcttc tgttactctt
      121 agctccagtg atttaagccc tacctttgga cactgcttac ccagtagcta ccaaggaaat
      181 ctctggctcc tggattactg ccaagaatcc tacggtgaag caccaacctg caaatctccc
      241 agctgtgagc ccaagacctg cagtaccact ggttgtgacc cgtcaaactc ctctgtgccc
      301 tgcaactccc catcagcagg ccaagtcttc agtgtctgtg aaactaccaa cgtcagcccc
      361 agccccagct gcagcccaag cacccagacc aatgggtatg tatgcaattg ccacataccc
      421 actcgaaatg catccaaagc ctgccaaacc ctccgcaacg gttccaactg ctttggacaa
      481 cttaactgct tatccaagag tttccaaact ctaaaccact gcagattgag tactttgggg
      541 tataaaagct accaaaatcc ttgcttcata cccagctacg tctcaccatt atgttatatt
      601 tccaacagct gccaacccca aagctattta gtgagaaatt atcactattc aagctacagg
      661 cctacgagct gccgaccact gagctattta tctagaagct tcagatctct gagctatata
      721 cccagtacct ttccacctct gaggtatttg tgcagtggta gcagacctct gaaatgctat
      781 tgaccaactt ccagaattta tagcagctgg aaattgccca atggggaaga ttctactaag
      841 tactagaacg tctaattttc tgctgaatct ctttattcag cctaagaatc ttgttacatt
      901 aagttcaaat acaactccca ggtttattaa ccacagccag tatcacctgc taggttttct
      961 tttttctgtt gttctgttat tgctctttgt actaaaagct gaccctgaag gtaacatcat
     1021 tatttctgag atttattaca atggacttac cgaagagact ccatttgaaa tacaaccatc
     1081 accggctttc ttactttggc tgtcactgtc acttgtctga cagtgtgatt atcacctacc
     1141 tttcctgatg aaatggggcc tccatggttt gactgcagat tccagcatgc aaattcattc
     1201 ggatggcttt gattgtcatt aatatttttg tcaactacct aactagcacc ttgctaataa
     1261 gccgatagaa aacactatct tgagcataat aagttgaact atttcatcct tttcttactg
     1321 attgattgta agaacaggca aatagcaatg gtgactagag ctcaaaaata gaagacttca
     1381 gcaaatcttc tcttccagag aagccataaa acaagattca ctggtactca gcttttgttc
     1441 tccatgccta agaaaaagcc tcagaattag ctaaagcatg aaaattattt gttgaaagaa
     1501 gaacaaatac tgttagagac cctttacaat tatgtgtaat ctgcgtttag gattctccta
     1561 tcatcttgcc ttgccaattt attgcattct gactctggaa aatgtcctag ttcttagtta
     1621 ataaacaaat ttctgtctgg aa
//
