LOCUS       NM_181617                466 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens keratin associated protein 21-2 (KRTAP21-2), mRNA.
ACCESSION   NM_181617
VERSION     NM_181617.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 466)
  AUTHORS   Rogers,M.A., Langbein,L., Winter,H., Ehmann,C., Praetzel,S. and
            Schweizer,J.
  TITLE     Characterization of a first domain of human high glycine-tyrosine
            and high sulfur keratin-associated protein (KAP) genes on
            chromosome 21q22.1
  JOURNAL   J Biol Chem 277 (50), 48993-49002 (2002)
   PUBMED   12359730
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP000243.1.
            
            On May 17, 2019 this sequence version replaced NM_181617.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AB096959.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000333892.3/ ENSP00000334287.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-466               AP000243.1         81777-82242         c
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="21"
                     /map="21q22.11"
     gene            1..466
                     /gene="KRTAP21-2"
                     /gene_synonym="KAP21.2"
                     /note="keratin associated protein 21-2"
                     /db_xref="GeneID:337978"
                     /db_xref="HGNC:HGNC:18946"
     exon            1..466
                     /gene="KRTAP21-2"
                     /gene_synonym="KAP21.2"
                     /inference="alignment:Splign:2.1.0"
     CDS             58..309
                     /gene="KRTAP21-2"
                     /gene_synonym="KAP21.2"
                     /codon_start=1
                     /product="keratin-associated protein 21-2"
                     /protein_id="NP_853648.1"
                     /db_xref="CCDS:CCDS13605.1"
                     /db_xref="GeneID:337978"
                     /db_xref="HGNC:HGNC:18946"
                     /translation="MCCNYYRNCCGGCGYGSGWSSGCGYGCGYGCGYGSGCRYGSGYG
                     TGCGYGCGYGSGCGYGCGYSSSCCGYRPLCYRRCYSSCY"
ORIGIN      
        1 agtcacactt cagaaatatc ctcctacacc tcaactgaaa tctaacctcc tgaaatcatg
       61 tgttgcaact actacagaaa ctgctgtggg ggctgtggat atggctctgg ctggagttcc
      121 ggctgtggat atggttgtgg ctatggctgt ggatacggct ctggctgtag atatggctct
      181 ggctatggaa ctggctgtgg ctatggctgt ggatacggct ctggctgtgg atatggctgt
      241 ggatacagct ctagctgctg tggctaccga ccactttgct acagaagatg ctattcctct
      301 tgctactaat catcactaca ggtcatcctt ggctttgcaa tgacctctcc aagatcaagt
      361 tcaattgaaa tctcccctac ccattatctt cacatctaag taaaggttga ctatggtcac
      421 ctgactatct gaatgcatat aagagaagct gttggcagtg gatgga
//
