LOCUS       NM_181611                485 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens keratin associated protein 19-5 (KRTAP19-5), mRNA.
ACCESSION   NM_181611
VERSION     NM_181611.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 485)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   2  (bases 1 to 485)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 485)
  AUTHORS   Rogers,M.A., Langbein,L., Winter,H., Ehmann,C., Praetzel,S. and
            Schweizer,J.
  TITLE     Characterization of a first domain of human high glycine-tyrosine
            and high sulfur keratin-associated protein (KAP) genes on
            chromosome 21q22.1
  JOURNAL   J Biol Chem 277 (50), 48993-49002 (2002)
   PUBMED   12359730
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP000567.2.
            
            On May 17, 2019 this sequence version replaced NM_181611.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AB096946.1, BC128032.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000334151.3/ ENSP00000334985.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-485               AP000567.2         121913-122397       c
FEATURES             Location/Qualifiers
     source          1..485
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="21"
                     /map="21q22.11"
     gene            1..485
                     /gene="KRTAP19-5"
                     /gene_synonym="KAP19.5"
                     /note="keratin associated protein 19-5"
                     /db_xref="GeneID:337972"
                     /db_xref="HGNC:HGNC:18940"
     exon            1..485
                     /gene="KRTAP19-5"
                     /gene_synonym="KAP19.5"
                     /inference="alignment:Splign:2.1.0"
     CDS             52..270
                     /gene="KRTAP19-5"
                     /gene_synonym="KAP19.5"
                     /codon_start=1
                     /product="keratin-associated protein 19-5"
                     /protein_id="NP_853642.1"
                     /db_xref="CCDS:CCDS13597.1"
                     /db_xref="GeneID:337972"
                     /db_xref="HGNC:HGNC:18940"
                     /translation="MNYYGNYYGGLGYGYGGFDDLGYGYGCGCGSFRRLGYGGGYGGY
                     GYGSGFGGYGYRSCRPSCYGGYGFSGFY"
ORIGIN      
        1 acactcagga tcttgccttg agcagcatac caactcacca ctcctgacac catgaactac
       61 tacggcaact actatggagg cctgggctac ggctacggag gcttcgatga cctgggctat
      121 ggctatggct gtggatgtgg cagcttccgc agactgggct atggcggtgg ctacggaggc
      181 tacggatacg gctctggctt cggaggctat ggataccgca gctgccgtcc atcatgctat
      241 ggaggatatg gattctctgg attttattga aatccttccc tgacaaccta acatgagggg
      301 acataagaag atcacccaaa cctgactgca ataacaaaca aacgaggtca ccctggatca
      361 agccaagatc aagagcagtt agcatctaag aggtttaaga atacctatca ttccataatt
      421 ctttgcttta tgtctctgga tgtgtcttac ttgtaccttt ataactgtgg ggtttctctg
      481 ttcct
//
