LOCUS       NM_181621                882 bp    mRNA    linear   PRI 27-JUL-2024
DEFINITION  Homo sapiens keratin associated protein 13-2 (KRTAP13-2), mRNA.
ACCESSION   NM_181621
VERSION     NM_181621.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 882)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 882)
  AUTHORS   Rogers,M.A., Langbein,L., Winter,H., Ehmann,C., Praetzel,S. and
            Schweizer,J.
  TITLE     Characterization of a first domain of human high glycine-tyrosine
            and high sulfur keratin-associated protein (KAP) genes on
            chromosome 21q22.1
  JOURNAL   J Biol Chem 277 (50), 48993-49002 (2002)
   PUBMED   12359730
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP000885.1, BX104478.1 and W72002.1.
            
            On May 17, 2019 this sequence version replaced NM_181621.3.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AB096938.1, BX104478.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            MANE Ensembl match                 :: ENST00000399889.4/
                                                  ENSP00000382777.2
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-32                AP000885.1         78732-78763         c
            33-744              BX104478.1         18-729
            745-881             W72002.1           1-137               c
            882-882             AP000885.1         77882-77882         c
FEATURES             Location/Qualifiers
     source          1..882
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="21"
                     /map="21q22.11"
     gene            1..882
                     /gene="KRTAP13-2"
                     /gene_synonym="KAP13-2"
                     /note="keratin associated protein 13-2"
                     /db_xref="GeneID:337959"
                     /db_xref="HGNC:HGNC:18923"
     exon            1..882
                     /gene="KRTAP13-2"
                     /gene_synonym="KAP13-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             59..586
                     /gene="KRTAP13-2"
                     /gene_synonym="KAP13-2"
                     /codon_start=1
                     /product="keratin-associated protein 13-2"
                     /protein_id="NP_853652.1"
                     /db_xref="CCDS:CCDS13589.1"
                     /db_xref="GeneID:337959"
                     /db_xref="HGNC:HGNC:18923"
                     /translation="MSYNCCSGNFSSRSCGDYLRYPASSRGFSYPSNLVYSTDLCSPS
                     TCQLGSSLYRGCQEICWEPTSCQTSYVESSPCQTSCYRPRTSLLCSPCKTTYSGSLGF
                     GSSSCRSLGYGSRSCYSVGCGSSGVRSLGYGSCGFPSLGYGSGFCRPTYLASRSCQSP
                     CYRPAYGSTFCRSTC"
     regulatory      856..861
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KRTAP13-2"
                     /gene_synonym="KAP13-2"
                     /note="hexamer: AATAAA"
     polyA_site      882
                     /gene="KRTAP13-2"
                     /gene_synonym="KAP13-2"
                     /note="major polyA site"
ORIGIN      
        1 attcaaactc agagaatctt tccactataa ctcagctgaa ctcacatctc ccgtcaacat
       61 gtcctacaac tgctgctctg gaaacttctc ctcccgctcc tgtggtgact acctgcgcta
      121 cccagcatcc tcacgtggct tttcctaccc cagcaatctg gtctacagca ctgacctctg
      181 ctctcccagc acctgccagc tgggttcctc tctctatagg ggctgtcagg agatctgctg
      241 ggagcccacc agctgccaga cgtcctatgt ggagtccagc ccctgccaga cctcctgcta
      301 ccgccccaga acctccttgc tctgcagtcc ttgcaagacg acttactctg ggtctctagg
      361 ctttggatcc agcagctgcc gctccctggg ctatggatcg aggagctgct actcagtggg
      421 ctgtgggtcc agtggtgtca gatccctggg ttatggaagc tgtggcttcc cttccctcgg
      481 ctatggatct ggattctgcc gcccaaccta cttggcttct aggagctgcc agtctccttg
      541 ttacagacca gcctatggat caaccttctg cagatcaact tgctgaattt ccagaccttt
      601 taagcaaagt gtctcagtct ctacgtagag ctgttatcat aggcatttcc agcaatgtga
      661 gctaacccct cttactacta gctcttcatc ctttctctgg catcaagtac tggctggaca
      721 ggctagttct ttcagactgt gaaattaatg aatgagcaaa atatagagtc aaatgtctat
      781 aattttgaaa caagtgattc gttatcacgt aagttcatct tataaagtat atggaagttc
      841 agttttgttt cacgtaataa attcatttac tgttgattcc aa
//
