LOCUS       NM_198698                447 bp    mRNA    linear   PRI 27-JUL-2024
DEFINITION  Homo sapiens keratin associated protein 12-4 (KRTAP12-4), mRNA.
ACCESSION   NM_198698
VERSION     NM_198698.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 447)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 447)
  AUTHORS   Shibuya,K., Obayashi,I., Asakawa,S., Minoshima,S., Kudoh,J. and
            Shimizu,N.
  TITLE     A cluster of 21 keratin-associated protein genes within introns of
            another gene on human chromosome 21q22.3
  JOURNAL   Genomics 83 (4), 679-693 (2004)
   PUBMED   15028290
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AB076360.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AB076360.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000391618.1/ ENSP00000375476.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="21"
                     /map="21q22.3"
     gene            1..447
                     /gene="KRTAP12-4"
                     /gene_synonym="KRTAP12.4"
                     /note="keratin associated protein 12-4"
                     /db_xref="GeneID:386684"
                     /db_xref="HGNC:HGNC:20532"
     exon            1..447
                     /gene="KRTAP12-4"
                     /gene_synonym="KRTAP12.4"
                     /inference="alignment:Splign:2.1.0"
     CDS             46..384
                     /gene="KRTAP12-4"
                     /gene_synonym="KRTAP12.4"
                     /note="high sulfur keratin-associated protein 12.4"
                     /codon_start=1
                     /product="keratin-associated protein 12-4"
                     /protein_id="NP_941971.1"
                     /db_xref="CCDS:CCDS42963.1"
                     /db_xref="GeneID:386684"
                     /db_xref="HGNC:HGNC:20532"
                     /translation="MCHTSHSSGCPMACPGSPCCVPSTCYPPEGYGTSCCCSAPCVAL
                     LCRPLCGVSTCCQPACCVPSPCQVACCVPVSCKPVLCVASFCPTSGCCQPFCPTLVYR
                     PVTWSTPTGC"
ORIGIN      
        1 agaccagccc tgtcctctgc gccccccacc tgtccacact ccatcatgtg ccacaccagc
       61 cactcttcgg gctgcccaat ggcctgccct ggctccccgt gctgtgtccc cagcacctgc
      121 tacccacccg agggctatgg gacctcctgc tgctgctcag ccccctgtgt ggctctgctg
      181 tgccggcccc tgtgtggggt atccacctgc tgccagccag cctgctgtgt gcccagcccc
      241 tgccaggtgg cctgctgtgt gcctgtgagc tgcaagcctg ttttgtgtgt ggcttccttc
      301 tgcccaacct ctgggtgctg ccagcccttc tgccccaccc tggtctatag acctgtcacc
      361 tggagcaccc ccactggctg ctgagcaggt ggcctcctat gaccctcgta ggtgcgaggt
      421 cagaagccag caggctctct gaactcc
//
