LOCUS       NM_181686                588 bp    mRNA    linear   PRI 27-JUL-2024
DEFINITION  Homo sapiens keratin associated protein 12-1 (KRTAP12-1), mRNA.
ACCESSION   NM_181686
VERSION     NM_181686.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 588)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 588)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 588)
  AUTHORS   Shibuya,K., Obayashi,I., Asakawa,S., Minoshima,S., Kudoh,J. and
            Shimizu,N.
  TITLE     A cluster of 21 keratin-associated protein genes within introns of
            another gene on human chromosome 21q22.3
  JOURNAL   Genomics 83 (4), 679-693 (2004)
   PUBMED   15028290
REFERENCE   4  (bases 1 to 588)
  AUTHORS   Rogers,M.A., Langbein,L., Winter,H., Beckmann,I., Praetzel,S. and
            Schweizer,J.
  TITLE     Hair keratin associated proteins: characterization of a second high
            sulfur KAP gene domain on human chromosome 21
  JOURNAL   J Invest Dermatol 122 (1), 147-158 (2004)
   PUBMED   14962103
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. This record has been curated by NCBI staff in
            collaboration with Michael Rogers. The reference sequence was
            derived from AJ566388.1.
            
            On May 17, 2019 this sequence version replaced NM_181686.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AJ566388.1, AB076363.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000391617.1/ ENSP00000375475.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-588               AJ566388.1         1-588
FEATURES             Location/Qualifiers
     source          1..588
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="21"
                     /map="21q22.3"
     gene            1..588
                     /gene="KRTAP12-1"
                     /gene_synonym="KAP12.1; KRTAP12.1"
                     /note="keratin associated protein 12-1"
                     /db_xref="GeneID:353332"
                     /db_xref="HGNC:HGNC:20529"
     exon            1..588
                     /gene="KRTAP12-1"
                     /gene_synonym="KAP12.1; KRTAP12.1"
                     /inference="alignment:Splign:2.1.0"
     CDS             41..331
                     /gene="KRTAP12-1"
                     /gene_synonym="KAP12.1; KRTAP12.1"
                     /note="keratin-associated protein 12.1; high sulfur
                     keratin-associated protein 12.1"
                     /codon_start=1
                     /product="keratin-associated protein 12-1"
                     /protein_id="NP_859014.1"
                     /db_xref="CCDS:CCDS42966.1"
                     /db_xref="GeneID:353332"
                     /db_xref="HGNC:HGNC:20529"
                     /translation="MCHTSCSSGCQPACCAPSPCQASCYIPVGCQSSVCVPVSFKPAV
                     CVPVRCQSSVCVPVSCRPVVYAAPSCQSSGCCQPSCTSVLCRPISCSTPSCC"
ORIGIN      
        1 cactgccctc tgcctcgacc ttatccagcc acacgccacc atgtgccaca ccagctgctc
       61 ctcgggctgc cagccagcct gctgcgcgcc cagcccctgc caggcatcct gttacatccc
      121 cgtgggctgc cagtcctccg tgtgcgtgcc cgtgagcttc aagccagccg tgtgtgtgcc
      181 cgtgagatgc cagtcctctg tgtgcgtgcc cgtgagctgc aggcccgtcg tgtatgcggc
      241 tccctcctgc cagtcctctg ggtgctgcca gccttcctgc accagcgtcc tctgcagacc
      301 catctcctgc agcacccctt cctgctgctg agcatgaatc tccagacccg ctgctcccag
      361 tgcagatgag gccacacctg tacactccct ggatgagtcc tcagttggtc ttctgcacat
      421 ggtgcaggtg aaaagcatgc tcagtgaacc ctctgaattc tggatcgaga atataataga
      481 atgatctgga gccctggctg aacttgccta tccccccagg gaagtctggg gtcccagagt
      541 cattctctga ccccatgaga gtcaaataaa ccagctttcc ccatgcaa
//
