LOCUS       NM_175858                937 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens keratin associated protein 11-1 (KRTAP11-1), mRNA.
ACCESSION   NM_175858
VERSION     NM_175858.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 937)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   2  (bases 1 to 937)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 937)
  AUTHORS   Rechiche,O., Plowman,J.E., Harland,D.P., Lee,T.V. and Lott,J.S.
  TITLE     Expression and purification of high sulfur and high
            glycine-tyrosine keratin-associated proteins (KAPs) for biochemical
            and biophysical characterization
  JOURNAL   Protein Expr Purif 146, 34-44 (2018)
   PUBMED   29391282
  REMARK    GeneRIF: Expressed and purified are a high sulfur KAP (KAP11.1) and
            a high glycine-tyrosine KAP (KAP6.1).
REFERENCE   4  (bases 1 to 937)
  AUTHORS   Pruett,N.D., Tkatchenko,T.V., Jave-Suarez,L., Jacobs,D.F.,
            Potter,C.S., Tkatchenko,A.V., Schweizer,J. and Awgulewitsch,A.
  TITLE     Krtap16, characterization of a new hair keratin-associated protein
            (KAP) gene complex on mouse chromosome 16 and evidence for
            regulation by Hoxc13
  JOURNAL   J Biol Chem 279 (49), 51524-51533 (2004)
   PUBMED   15385554
REFERENCE   5  (bases 1 to 937)
  AUTHORS   Rogers,M.A., Langbein,L., Winter,H., Ehmann,C., Praetzel,S. and
            Schweizer,J.
  TITLE     Characterization of a first domain of human high glycine-tyrosine
            and high sulfur keratin-associated protein (KAP) genes on
            chromosome 21q22.1
  JOURNAL   J Biol Chem 277 (50), 48993-49002 (2002)
   PUBMED   12359730
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. This record has been curated by NCBI staff in
            collaboration with Michael Rogers. The reference sequence was
            derived from AP000244.1 and AJ457065.1.
            
            On May 17, 2019 this sequence version replaced NM_175858.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AJ457065.1, BC130557.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000332378.6/ ENSP00000330720.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-25                AP000244.1         120689-120713       c
            26-937              AJ457065.1         1-912
FEATURES             Location/Qualifiers
     source          1..937
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="21"
                     /map="21q22.11"
     gene            1..937
                     /gene="KRTAP11-1"
                     /gene_synonym="HACL-1; HACL1; KAP11.1"
                     /note="keratin associated protein 11-1"
                     /db_xref="GeneID:337880"
                     /db_xref="HGNC:HGNC:18922"
                     /db_xref="MIM:600064"
     exon            1..937
                     /gene="KRTAP11-1"
                     /gene_synonym="HACL-1; HACL1; KAP11.1"
                     /inference="alignment:Splign:2.1.0"
     CDS             57..548
                     /gene="KRTAP11-1"
                     /gene_synonym="HACL-1; HACL1; KAP11.1"
                     /note="high sulfur keratin-associated protein 11.1"
                     /codon_start=1
                     /product="keratin-associated protein 11-1"
                     /protein_id="NP_787054.1"
                     /db_xref="CCDS:CCDS13608.1"
                     /db_xref="GeneID:337880"
                     /db_xref="HGNC:HGNC:18922"
                     /db_xref="MIM:600064"
                     /translation="MSFNCSTRNCSSRPIGGRCIVPVAQVTTTSTTDADCLGGICLPS
                     SFQTGSWLLDHCQETCCEPTACQPTCYRRTSCVSNPCQVTCSRQTTCISNPCSTTYSR
                     PLTFVSSGCQPLGGISSVCQPVGGISTVCQPVGGVSTVCQPACGVSRTYQQSCVSSCR
                     RTC"
ORIGIN      
        1 attcacaact caggaggtaa cttcagcaag ctacctgcag ccctctgtct gacatcatgt
       61 ccttcaactg ctccacaaga aattgctctt ccaggcccat tggaggacgc tgcattgttc
      121 cagtggccca agttaccacg acttccacca ctgatgctga ctgcctgggc ggcatctgtt
      181 tgcccagttc cttccagact ggctcttggc tcctggacca ctgtcaagag acctgctgtg
      241 agcccactgc ttgccagcca acctgttacc ggcgaacttc atgtgtctcc aacccttgcc
      301 aggtgacttg ctctcgacaa actacctgta tttccaaccc ctgctcaact acctacagcc
      361 ggccgctcac ctttgtctct agtggatgtc agcccctggg aggcatctcc agtgtctgcc
      421 aaccagtggg cggcatctct actgtctgcc aaccagtggg aggagtctct actgtctgcc
      481 agccagcctg tggggtctcc aggacgtatc agcagtcctg cgtgtccagc tgccgaagaa
      541 cctgctaagt gtgtaggagc cagtgagcga atcaagactc cacgacctgc cagctgtttc
      601 caggatcttc cagcatgctg cttgtccctg aatagctctt catagctgac ccttcttgtg
      661 accgcctgac tgctggctac tatccatgca cacgctgtct ttagcactct aaaatttttc
      721 tggccagccc taagcttgtt ttaagggttg ctcactggtg ctgtgtatgc ctctggatgt
      781 gtccagaagc tttaccatcc acaccccagt ctctgatgct tttgacatgt tttcaccttg
      841 ctgctgtatc tcctggcctc tgcttttgtg tctcacaaaa acagagcttg tctcaccatg
      901 tatttctcaa taaacctgca ttagttggca ttgcaaa
//
