LOCUS       NM_198688               1238 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens keratin associated protein 10-6 (KRTAP10-6), mRNA.
ACCESSION   NM_198688
VERSION     NM_198688.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1238)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1238)
  AUTHORS   Shibuya,K., Obayashi,I., Asakawa,S., Minoshima,S., Kudoh,J. and
            Shimizu,N.
  TITLE     A cluster of 21 keratin-associated protein genes within introns of
            another gene on human chromosome 21q22.3
  JOURNAL   Genomics 83 (4), 679-693 (2004)
   PUBMED   15028290
REFERENCE   3  (bases 1 to 1238)
  AUTHORS   Rogers,M.A., Langbein,L., Winter,H., Beckmann,I., Praetzel,S. and
            Schweizer,J.
  TITLE     Hair keratin associated proteins: characterization of a second high
            sulfur KAP gene domain on human chromosome 21
  JOURNAL   J Invest Dermatol 122 (1), 147-158 (2004)
   PUBMED   14962103
REFERENCE   4  (bases 1 to 1238)
  AUTHORS   Rogers,M.A., Langbein,L., Winter,H., Ehmann,C., Praetzel,S. and
            Schweizer,J.
  TITLE     Characterization of a first domain of human high glycine-tyrosine
            and high sulfur keratin-associated protein (KAP) genes on
            chromosome 21q22.1
  JOURNAL   J Biol Chem 277 (50), 48993-49002 (2002)
   PUBMED   12359730
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AB076353.1.
            
            On Apr 18, 2014 this sequence version replaced NM_198688.2.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AB076353.1, BC140725.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000400368.1/ ENSP00000383219.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1238              AB076353.1         1-1238
FEATURES             Location/Qualifiers
     source          1..1238
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="21"
                     /map="21q22.3"
     gene            1..1238
                     /gene="KRTAP10-6"
                     /gene_synonym="KAP10.6; KAP18.6; KRTAP18-6; KRTAP18.6"
                     /note="keratin associated protein 10-6"
                     /db_xref="GeneID:386674"
                     /db_xref="HGNC:HGNC:20523"
     exon            1..1238
                     /gene="KRTAP10-6"
                     /gene_synonym="KAP10.6; KAP18.6; KRTAP18-6; KRTAP18.6"
                     /inference="alignment:Splign:2.1.0"
     CDS             22..1119
                     /gene="KRTAP10-6"
                     /gene_synonym="KAP10.6; KAP18.6; KRTAP18-6; KRTAP18.6"
                     /note="keratin associated protein 18-6; high sulfur
                     keratin-associated protein 10.6"
                     /codon_start=1
                     /product="keratin-associated protein 10-6"
                     /protein_id="NP_941961.3"
                     /db_xref="CCDS:CCDS42959.1"
                     /db_xref="GeneID:386674"
                     /db_xref="HGNC:HGNC:20523"
                     /translation="MAASTMSVCSSDLSYGSRVCLPGSCDSCSDSWQVDDCPESCCEP
                     PCCAPAPCLSLVCTPVSRVSSPCCPVTCEPSPCQSGCTSSCTPSCCQQSSCQLACCAS
                     SPCQQACCVPVCCKTVCCKPVCCVSVCCGDSSCCQQSSCQSACCTSSPCQQACCVPVC
                     CKPVCSGISSSCCQQSSCVSCVSSPCCQAVCEPSPCQSGCTSSCTPSCCQQSSCQPTC
                     CTSSPCQQACCVPVCCVPVCCVPTCSEDSSSCCQQSSCQPACCTSSPCQHACCVPVCS
                     GASTSCCQQSSCQPACCTASCCRSSSSVSLLCHPVCKSTCCVPVPSCGASASSCQPSC
                     CRTASCVSLLCRPMCSRPACYSLCSGQKSSC"
ORIGIN      
        1 ctccaccagt tcaaccccag catggccgcg tccaccatgt ccgtctgctc cagcgacctg
       61 agctacggca gccgcgtctg ccttcctggt tcctgtgact cttgctccga ctcctggcag
      121 gtggacgact gcccagagag ctgctgtgag cccccctgct gcgccccggc cccctgcctg
      181 agcctggtct gcaccccagt gagccgtgtg tccagcccct gctgcccagt gacctgtgag
      241 cccagcccct gccaatcagg ctgcaccagc tcctgcacgc cctcgtgctg ccagcagtct
      301 agctgccagc tggcttgctg tgcctcctcc ccctgccagc aggcctgctg cgtgcccgtc
      361 tgctgcaaga ctgtctgctg caagcctgtg tgctgtgtgt ccgtctgctg tggggattct
      421 tcatgctgcc agcagtctag ctgccagtca gcttgctgca cctcctcccc ctgccagcag
      481 gcctgctgtg tgcccgtctg ctgcaagcct gtctgctctg ggatttcctc ttcgtgctgc
      541 cagcagtcta gctgtgtgag ctgtgtgtcc agcccctgct gccaggcggt ctgtgagccc
      601 agcccctgcc aatcaggctg caccagctcc tgcacaccct catgctgcca gcagtctagc
      661 tgccagccaa cttgctgcac ctcctccccc tgccagcagg cctgctgcgt gcccgtctgc
      721 tgcgtgcctg tgtgctgtgt gcccacctgc tctgaggatt cctcttcatg ctgccagcag
      781 tctagctgcc agccagcttg ctgcacctcc tccccctgcc agcacgcctg ctgtgtgccc
      841 gtctgctctg gggcttccac atcatgctgc cagcagtcta gctgccagcc ggcttgctgc
      901 accgcctcct gctgcagatc ctcctcctcc gtgtccctcc tctgccaccc tgtgtgcaag
      961 tccacctgct gcgtgcccgt cccctcctgt ggtgcctctg cctcctcctg ccagcccagc
     1021 tgctgccgca cggcctcctg tgtttccctc ctctgccgcc ccatgtgctc ccgccctgcc
     1081 tgctacagcc tctgctctgg ccagaagtcc agctgctgac agccctggat gtgatccgga
     1141 gtcccttccc accaggggct gacctcccag ctgccccagc aagctctgcc ctctctggct
     1201 ttgacaccct cagaagatgg ggcaggctct ttgtctta
//
