LOCUS       NM_012316               7355 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens karyopherin subunit alpha 6 (KPNA6), mRNA.
ACCESSION   NM_012316
VERSION     NM_012316.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7355)
  AUTHORS   Cho,N.H., Cheveralls,K.C., Brunner,A.D., Kim,K., Michaelis,A.C.,
            Raghavan,P., Kobayashi,H., Savy,L., Li,J.Y., Canaj,H., Kim,J.Y.S.,
            Stewart,E.M., Gnann,C., McCarthy,F., Cabrera,J.P., Brunetti,R.M.,
            Chhun,B.B., Dingle,G., Hein,M.Y., Huang,B., Mehta,S.B.,
            Weissman,J.S., Gomez-Sjoberg,R., Itzhak,D.N., Royer,L.A., Mann,M.
            and Leonetti,M.D.
  TITLE     OpenCell: Endogenous tagging for the cartography of human cellular
            organization
  JOURNAL   Science 375 (6585), eabi6983 (2022)
   PUBMED   35271311
REFERENCE   2  (bases 1 to 7355)
  AUTHORS   Yu,M., Sun,L., Zhang,Z., Zhang,Y., Zhang,H., Na,L. and Wang,X.
  TITLE     KPNA6 is a Cofactor of ANP32A/B in Supporting Influenza Virus
            Polymerase Activity
  JOURNAL   Microbiol Spectr 10 (1), e0207321 (2022)
   PUBMED   35044222
  REMARK    GeneRIF: KPNA6 is a Cofactor of ANP32A/B in Supporting Influenza
            Virus Polymerase Activity.
REFERENCE   3  (bases 1 to 7355)
  AUTHORS   Tsimbalyuk,S., Donnelly,C.M. and Forwood,J.K.
  TITLE     Structural characterization of human importin alpha 7 in its
            cargo-free form at 2.5 A resolution
  JOURNAL   Sci Rep 12 (1), 315 (2022)
   PUBMED   35013395
  REMARK    GeneRIF: Structural characterization of human importin alpha 7 in
            its cargo-free form at 2.5 A resolution.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 7355)
  AUTHORS   Zhang,Q., Chen,Z., Huang,C., Sun,J., Xue,M., Feng,T., Pan,W.,
            Wang,K. and Dai,J.
  TITLE     Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
            Membrane (M) and Spike (S) Proteins Antagonize Host Type I
            Interferon Response
  JOURNAL   Front Cell Infect Microbiol 11, 766922 (2021)
   PUBMED   34950606
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7355)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   6  (bases 1 to 7355)
  AUTHORS   Di Marzio,P., Choe,S., Ebright,M., Knoblauch,R. and Landau,N.R.
  TITLE     Mutational analysis of cell cycle arrest, nuclear localization and
            virion packaging of human immunodeficiency virus type 1 Vpr
  JOURNAL   J Virol 69 (12), 7909-7916 (1995)
   PUBMED   7494303
REFERENCE   7  (bases 1 to 7355)
  AUTHORS   Gallay,P., Swingler,S., Song,J., Bushman,F. and Trono,D.
  TITLE     HIV nuclear import is governed by the phosphotyrosine-mediated
            binding of matrix to the core domain of integrase
  JOURNAL   Cell 83 (4), 569-576 (1995)
   PUBMED   7585960
REFERENCE   8  (bases 1 to 7355)
  AUTHORS   Freed,E.O., Englund,G. and Martin,M.A.
  TITLE     Role of the basic domain of human immunodeficiency virus type 1
            matrix in macrophage infection
  JOURNAL   J Virol 69 (6), 3949-3954 (1995)
   PUBMED   7745752
REFERENCE   9  (bases 1 to 7355)
  AUTHORS   Bukrinsky,M.I., Sharova,N., Dempsey,M.P., Stanwick,T.L.,
            Bukrinskaya,A.G., Haggerty,S. and Stevenson,M.
  TITLE     Active nuclear import of human immunodeficiency virus type 1
            preintegration complexes
  JOURNAL   Proc Natl Acad Sci U S A 89 (14), 6580-6584 (1992)
   PUBMED   1631159
REFERENCE   10 (bases 1 to 7355)
  AUTHORS   Sharova,N. and Bukrinskaya,A.
  TITLE     p17 and p17-containing gag precursors of input human
            immunodeficiency virus are transported into the nuclei of infected
            cells
  JOURNAL   AIDS Res Hum Retroviruses 7 (3), 303-306 (1991)
   PUBMED   2064827
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BP374991.1, BC020520.1 and
            AL049795.21.
            
            On Nov 24, 2018 this sequence version replaced NM_012316.4.
            
            Summary: Nucleocytoplasmic transport, a signal- and
            energy-dependent process, takes place through nuclear pore
            complexes embedded in the nuclear envelope. The import of proteins
            containing a nuclear localization signal (NLS) requires the NLS
            import receptor, a heterodimer of importin alpha and beta subunits
            also known as karyopherins. Importin alpha binds the NLS-containing
            cargo in the cytoplasm and importin beta docks the complex at the
            cytoplasmic side of the nuclear pore complex. In the presence of
            nucleoside triphosphates and the small GTP binding protein Ran, the
            complex moves into the nuclear pore complex and the importin
            subunits dissociate. Importin alpha enters the nucleoplasm with its
            passenger protein and importin beta remains at the pore. The
            protein encoded by this gene is a member of the importin alpha
            family. [provided by RefSeq, Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK002111.1, BC020520.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000373625.8/ ENSP00000362728.3
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-12                BP374991.1         14-25
            13-3301             BC020520.1         1-3289
            3302-7355           AL049795.21        61838-65891
FEATURES             Location/Qualifiers
     source          1..7355
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p35.2"
     gene            1..7355
                     /gene="KPNA6"
                     /gene_synonym="IPOA7"
                     /note="karyopherin subunit alpha 6"
                     /db_xref="GeneID:23633"
                     /db_xref="HGNC:HGNC:6399"
                     /db_xref="MIM:610563"
     exon            1..79
                     /gene="KPNA6"
                     /gene_synonym="IPOA7"
                     /inference="alignment:Splign:2.1.0"
     CDS             76..1686
                     /gene="KPNA6"
                     /gene_synonym="IPOA7"
                     /note="importin-alpha-S2; importin alpha 7 subunit;
                     karyopherin alpha 6 (importin alpha 7)"
                     /codon_start=1
                     /product="importin subunit alpha-7"
                     /protein_id="NP_036448.1"
                     /db_xref="CCDS:CCDS352.1"
                     /db_xref="GeneID:23633"
                     /db_xref="HGNC:HGNC:6399"
                     /db_xref="MIM:610563"
                     /translation="METMASPGKDNYRMKSYKNNALNPEEMRRRREEEGIQLRKQKRE
                     QQLFKRRNVELINEEAAMFDSLLMDSYVSSTTGESVITREMVEMLFSDDSDLQLATTQ
                     KFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRNENCTLQFEAAWALTNIASGTSQQT
                     KIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLL
                     TKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADACWAL
                     SYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNIVTGDDIQTQVILN
                     CSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKAEF
                     RTRKEAAWAITNATSGGTPEQIRYLVSLGCIKPLCDLLTVMDSKIVQVALNGLENILR
                     LGEQEGKRSGSGVNPYCGLIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVEDDD
                     SSLAPQVDETQQQFIFQQPEAPMEGFQL"
     exon            80..213
                     /gene="KPNA6"
                     /gene_synonym="IPOA7"
                     /inference="alignment:Splign:2.1.0"
     exon            214..306
                     /gene="KPNA6"
                     /gene_synonym="IPOA7"
                     /inference="alignment:Splign:2.1.0"
     exon            307..406
                     /gene="KPNA6"
                     /gene_synonym="IPOA7"
                     /inference="alignment:Splign:2.1.0"
     exon            407..501
                     /gene="KPNA6"
                     /gene_synonym="IPOA7"
                     /inference="alignment:Splign:2.1.0"
     exon            502..633
                     /gene="KPNA6"
                     /gene_synonym="IPOA7"
                     /inference="alignment:Splign:2.1.0"
     exon            634..722
                     /gene="KPNA6"
                     /gene_synonym="IPOA7"
                     /inference="alignment:Splign:2.1.0"
     exon            723..822
                     /gene="KPNA6"
                     /gene_synonym="IPOA7"
                     /inference="alignment:Splign:2.1.0"
     exon            823..986
                     /gene="KPNA6"
                     /gene_synonym="IPOA7"
                     /inference="alignment:Splign:2.1.0"
     exon            987..1065
                     /gene="KPNA6"
                     /gene_synonym="IPOA7"
                     /inference="alignment:Splign:2.1.0"
     exon            1066..1191
                     /gene="KPNA6"
                     /gene_synonym="IPOA7"
                     /inference="alignment:Splign:2.1.0"
     exon            1192..1319
                     /gene="KPNA6"
                     /gene_synonym="IPOA7"
                     /inference="alignment:Splign:2.1.0"
     exon            1320..1498
                     /gene="KPNA6"
                     /gene_synonym="IPOA7"
                     /inference="alignment:Splign:2.1.0"
     exon            1499..7355
                     /gene="KPNA6"
                     /gene_synonym="IPOA7"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7334..7339
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KPNA6"
                     /gene_synonym="IPOA7"
                     /note="hexamer: AATAAA"
     polyA_site      7355
                     /gene="KPNA6"
                     /gene_synonym="IPOA7"
                     /note="major polyA site"
ORIGIN      
        1 atattgtcta ctgaaagctg ccgctgaagc tgccgccgtt gcctccgccg ccaagagtga
       61 gcgagcggac ccgcgatgga gaccatggcg agcccaggga aagacaatta tcgaatgaag
      121 agctataaga acaatgctct aaaccctgaa gaaatgagac gaagaagaga ggaagagggc
      181 attcagctcc ggaagcagaa gcgagagcaa caacttttta aacggagaaa tgtggagctg
      241 attaatgaag aagctgccat gttcgatagt cttctcatgg actcttatgt gagctctacc
      301 actggggaga gtgtgatcac aagagagatg gtggagatgc tcttttctga tgattctgac
      361 ctgcagttag caaccacaca gaaattccgg aaactgctct ccaaagagcc tagtcctcca
      421 atagatgaag ttatcaacac tccaagagtg gtggatcggt tcgtggagtt tctgaagagg
      481 aatgagaatt gtacattaca gtttgaagct gcctgggctc taacgaatat tgcctctgga
      541 acctctcagc agaccaaaat tgtcattgaa gcaggggctg tccccatttt tatagagctg
      601 cttaattcag actttgagga tgttcaggaa caggcagtct gggcactggg aaacatagct
      661 ggagatagct ctgtttgccg agattacgtc ttgaactgtt ccatccttaa tcctttgtta
      721 acactcctta ccaagtccac acgactgacg atgacacgga atgcagtctg ggccctgtca
      781 aatctctgcc gagggaaaaa cccaccccca gagtttgcaa aggtctctcc ttgtttgcct
      841 gtactgtctc gcctactctt cagcagcgac tcggacttgc tggcagatgc ttgctgggcc
      901 ctttcttatc tgtctgatgg ccccaatgag aagatccagg cagtcataga ctccggagtc
      961 tgccggagat tggtagagct gctgatgcac aatgattaca aagtggcttc tcctgccctg
     1021 agagccgtgg gtaacatcgt cactggggat gacatccaga cccaggtcat tcttaactgt
     1081 tcagccctac cttgccttct ccacttgttg agcagtccca aggagtcaat ccggaaggaa
     1141 gcttgctgga ctatttcaaa tattactgct ggcaacaggg ctcaaataca ggctgttata
     1201 gatgcaaata tcttccctgt gttgatcgaa atccttcaga aagcagagtt tcgtacaagg
     1261 aaagaggcag cctgggccat caccaatgcc acatcaggag gaacccctga gcagatcagg
     1321 tacctggtct cactgggctg catcaaaccc ctatgtgact tgctgactgt aatggattcg
     1381 aagattgtgc aagtggccct caatggactg gagaacatcc tgcggcttgg agagcaagag
     1441 ggcaagcgca gtggctcagg ggtcaatcct tattgtggcc tcatagagga agcctatggc
     1501 ttggataaaa ttgagtttct ccagagccac gagaaccagg agatctacca gaaggccttc
     1561 gacctcattg agcactactt tggtgtagaa gacgatgata gcagcctggc tccccaagtc
     1621 gatgaaacgc aacagcagtt catcttccag cagcctgagg cccccatgga gggcttccag
     1681 ctataatatc tgcctccagg gaggggaggg gatgggaagc accaccagcc agcggaagag
     1741 cagccctctg gtgggcggga aaccagtgtc cccaccatca gccaccacac acctctgctg
     1801 ccctggagac tgtgctcttg acctgctccg cccccttccc tggagggagc accctctgga
     1861 cagacagaac catctgaggc tcacctttgg gttttgtgac aagaagggga cgtgttgggt
     1921 ttttcttcct tacactatat tttggctgca cacatgtctt taacccagga gcccaggggt
     1981 agacaaagga ggactaaggt aatcaatttg cacctttttt tatttttatt ttttttcttt
     2041 ttttcttcag tggtgacttc cttcccttta tcttttttca ttcttcccgg tcctctgccc
     2101 tgatctgtgt aactcttatc ttgggtactt gagcagacgg tatattccag aggtgggagg
     2161 tgggagggga agggagaaat ccaaaacaaa gtgttcttgc tctgacagaa tattaatctt
     2221 gtacgcttgg attgagttat ttaatttttt tttcttttgc acatttttct tgtattaaga
     2281 ttgctcttcc caagagccac aagttcctgg ttttagtaaa cccagctgcc tgcattgcct
     2341 gggactagag gctggggagg ctaccatgaa acaaaggtcc ctccctccct ctgactcttt
     2401 gcccagacct ctttagtttg ggggatcctc ctcactctcc tgaagtgtct caagtatacc
     2461 agtgggagtg caggggagga gcacaggcct tcagatgggg cttcccacgt gtagctactg
     2521 atcccatatt tcctactcac cttccaaatg gtgcgaccca acttcatttg tttacttgaa
     2581 aattccccct cgaggttgag agaacctctg aggtggctgt attttctcct aagcttgaga
     2641 tagggggctg tggtccttcc tttctcctga ggagaaagtc cttgctctgg tgacctgtaa
     2701 gttgcagagg agggtggagt gagagtgtca tgtattggga tagtcaggga tccctgcctt
     2761 tggcctttct tcttcttctt cttcctcttc catagttgga tcatgtatat tttacttcta
     2821 aaggagagaa tgtcaaaaag ttctgtattt ttttatattc tatatattag gtaggtcaat
     2881 cttaattggt ctcaagagga agaactgtct gtcatttcgg taagtaggat actgtgagga
     2941 agaccaaaaa gagatatgga tgcttcctcg ctcaggaggc ctgagcttgg tccttttcct
     3001 ctctgcttgg attctggacc accacctggg accaaccttc agctctggaa ccttcataaa
     3061 gcaggtcagc gtggcctgat tgtcccagga cctgaaggga gcaaggatgg cctcagggcc
     3121 tggtgaagtc tgctactctg tccttactgc tgaacatcct gcttgtatca ggaaactcag
     3181 aagcagtttg ccttgtcaaa ttcaatctca atggccattg tccacataac tgatcaccca
     3241 tggctgcctc tcctattatc tattatcact gaaacttagt agcctgcttt tttttttttt
     3301 ttttttagag ctattgcgta tcttccctgt ttgggatcct tgtacctggt ttgggttttc
     3361 ccttccttgt gacaattata atccagatgc ctcttctttc tgtttgaatt acggtagtgc
     3421 attgccttag tggcttgcct gtgcctctgg gtggattaca tatgatagta aagcccacct
     3481 gtttggatgg gagtagagga agttggtgta gaccagctgt ggagctgaag gcacagtctg
     3541 ccccaccccc acctccccac tgtggttagt cagaggcatc ctgctccaag ctctgctttt
     3601 ccttcctctg aaacaatgcc attcttgctt ctattgctac acatctcctt ctggctcagg
     3661 tgaaatccat gcccttctgc ttatagacct aaagttcagg tacttattat tggccattga
     3721 tcttgaattt gccctctcct agtgctgcag tcccacttca aagccatttt ctgaggagga
     3781 tggtttaggt ctggcaattg tccttgaaaa atcccaccca tgttgtacca ccttggtgag
     3841 tcatatgcca ctcatcagct tgggaatgat ggctgccaac tcccaatctc ccaggaaggc
     3901 agggggcaga atcttttttt cacttggcct gctacctcca ttaaaaaacc attctcttac
     3961 agtttaaaaa aaaaaaaaaa aaaaaagcct tcccctaccc aacctccgcc cattgttctc
     4021 ttccaaaggg caatttagta ggatctactt tgtacatctc aagtaagagt taagtccctg
     4081 atacagggac cagtttctta gtgtaagaca tacacatcct gcttgtccag ctgttcctcc
     4141 aaaatctact ttggcttcag ctccgggtcc tgtaccagat ggaaaatgtt tttggtgatc
     4201 tggctgctgc ttaaagccag ttttccctaa gaactccaaa ggctaaagtc tactaggggc
     4261 agagtgtgag gatagatttc taatcagaga aaagtggcct ccaggagctt tcatttatgt
     4321 cttctccaga ccaggttttc ctgttatctt cctttaatcc cctttcaacc aacaggtgaa
     4381 gttcttccag cccacagagg tagtaatatc atcttttcta tctcctcctc tcctttggcc
     4441 atgtaatgaa gcaaaatatt atttatttag cccaggcttg agagccactg tttgtggaca
     4501 gtcttcatct agattccata ccctggccta ggcgaggtaa ggctctctgg ttattgccag
     4561 gatggagccc ctctacccca gtctgctgta gggaataccc taattagttg aggcatgctt
     4621 ttggaatcct ggcatgttgg catatggctg gtctatcctt tttaagatct ctggttgggg
     4681 gtatctggat atggattagg agggacaagg agcctttttc ttggctaatg ttttccaata
     4741 cttttttgaa tggtgccagc ccctccaggc atcccacccc caaatcatca tctttagtac
     4801 taacagggtg tctggtctta gaagcctccc ttcagatccc agctgaccct ggtgactgcc
     4861 tggccttgat gttggctgca gccttctgat agaaccacat ggattccacc cacagctggc
     4921 caggcttgtt acatgggtca gggaatacaa atggcccccc cccagggagc aggtgttggc
     4981 ctcagttttc agggaccctt ggtgttgctc cttacctaga gcccattaat ctaccccatc
     5041 aactctctgc catgaaagcc atcttccagg agccctgttt tttggagctg aactgcacag
     5101 attatagctg ctattgtact taaataaggg agaggaaaag aaggttctca ggcacagact
     5161 ttctattttt ctcaagccaa accagtttaa aatgtctagc agaatgaact gtatttccat
     5221 ttcttcatgt ctacctgcct tccccccaca ccctaaagtt gtacttgttt ctagcaaact
     5281 agaaggaaaa gataggaaag cctggcacta ctaacctcac ctctcataca cctctttgaa
     5341 ggccccagct cttttgttca ggcctctctt ctcccctaga ctcactcagc ttggtatcca
     5401 tcatcttgag cattcttcag tagattcatc tagggttcag attccagact ctcagctgaa
     5461 gacagggagc caatttcccc caggtccctg caggtaatcc agggacccca tagggagaac
     5521 aggctgactg gggcattagg aatgtttgta cctctctgct tccctggcag cctggggaag
     5581 ggtgcagggc tcagtgcgct aaaccatggt aaacatcttc aatagaacta ccctagaatt
     5641 tagtgagtgt gagactgaga tattgctcag aataaattta ttccatagcc atttaggatt
     5701 gcatgttctg gaccaacctt gtccagtatg ttttctgttt gagctttttc attcttttgt
     5761 taagccaaca agttgagaat ttggccctgc tgggatccat gtagtgggca ctagctgctc
     5821 tttggccaag gccttcataa atgattcagt ctctcattat ctgtcctcta gccccacacc
     5881 ctgatttaga ccgtggcaaa ggaagaactt gaggtcaaga ccaaccaaat ctgtgaatta
     5941 aagctgttat ttttttctct gcaagggcgc tttgcttcag gtctgggcta tgtgcagaac
     6001 ctaagcaggc tgtgagagtt agaagaggca gtattacatg ttaggcccag aacaccatgg
     6061 gaaaaggttt atgtagtgta tcttagtggc ctgcctagct gcctctgggc caggctgact
     6121 tctgatgtcc acattagctc gtacctgaac cctgttgctg aatgccagcc ctgttctcct
     6181 gtaactatta tatacgccat ggcctggggg gcattgaagg aagtaagctc tcagagatcc
     6241 taacactggc tgggaacctc tgactcagag catgtcttta aagagtccac atctggccag
     6301 gcgcggtggc acatgcctgt aatcccagca ctttgggagg ccgaggcggg tggatcacga
     6361 ggtcaggagt ttgagaccag cctggcaaca tagtgaaacc ccatctctaa taaaaataca
     6421 aaaaattagc tgggcgtggt ggcaggcgcc tgtaatccca gctacttggg aggctgagac
     6481 aggagaatca cttgaaccca ggaggcggag gttgcagtga gccaagatca tgccactgca
     6541 ctccagcttg ggtgacagtg cgagactcca tctcaaaaaa aaaaaaaaaa aaaaaatcca
     6601 catcttcagc tgggcgcggt ggctcatgcc tgtaatccta gcactttggg aggctgaggc
     6661 gggcagatca cttgaggtta ggggttcaaa accagcctga ccaacatagt aaaaccccgt
     6721 ccctacaaaa ataaaaaaat aaaaaaaata agccaggtgt ggtggtgggc acctgtgatc
     6781 tcagctacgt gggaggctga ggcaggagaa tctcttgaac ctaggaggca gaggttgcag
     6841 tgagccaaga ttgtgccagc ctgggcgaca gggtgaggct cttgtctcaa aaaaaaaagt
     6901 ccacatcttc atgaaccctc agactctgga gttgggtgtc ggctttttta gccagctttt
     6961 gtgggaattg cctttgacct attaaagaag gaaagtgggt aatggagtcc cagccactca
     7021 agagactgga tatcccccga gaatggcttg ggttaccagc tatggaccct tggaagatga
     7081 atctaatcct tctcactggt ttttctttgc aaattcattt gcttttattt ttctaataac
     7141 aataaactct attttccatg ttctcagggc ccctgggtag acagacacag cttgatttca
     7201 gagcagacat aggcgaagaa aacatggcat tgagtgtgct gagtccagac aaatgttatt
     7261 tatatacaca tccaaatttg aagagaaaat gtatttcttt aggtttcaaa cactgtaata
     7321 gatataaagc aaaaataaaa acctgttgca aagtt
//
