LOCUS       NM_003482              20635 bp    mRNA    linear   PRI 29-OCT-2024
DEFINITION  Homo sapiens lysine methyltransferase 2D (KMT2D), mRNA.
ACCESSION   NM_003482 XM_005269162
VERSION     NM_003482.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 20635)
  AUTHORS   Liu,W., Cao,H., Wang,J., Elmusrati,A., Han,B., Chen,W., Zhou,P.,
            Li,X., Keysar,S., Jimeno,A. and Wang,C.Y.
  TITLE     Histone-methyltransferase KMT2D deficiency impairs the Fanconi
            anemia/BRCA pathway upon glycolytic inhibition in squamous cell
            carcinoma
  JOURNAL   Nat Commun 15 (1), 6755 (2024)
   PUBMED   39117659
  REMARK    GeneRIF: Histone-methyltransferase KMT2D deficiency impairs the
            Fanconi anemia/BRCA pathway upon glycolytic inhibition in squamous
            cell carcinoma.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20635)
  AUTHORS   Wu,J., Chun,C., Lagunas,A.M. and Crowe,D.L.
  TITLE     Lysine Methyltransferase 2D Regulates Immune Response and
            Metastasis in Head and Neck Cancer
  JOURNAL   Anticancer Res 44 (8), 3231-3242 (2024)
   PUBMED   39060071
  REMARK    GeneRIF: Lysine Methyltransferase 2D Regulates Immune Response and
            Metastasis in Head and Neck Cancer.
REFERENCE   3  (bases 1 to 20635)
  AUTHORS   Wu,C.J., Livak,F. and Ashwell,J.D.
  TITLE     The histone methyltransferase KMT2D maintains cellular
            glucocorticoid responsiveness by shielding the glucocorticoid
            receptor from degradation
  JOURNAL   J Biol Chem 300 (8), 107581 (2024)
   PUBMED   39025450
  REMARK    GeneRIF: The histone methyltransferase KMT2D maintains cellular
            glucocorticoid responsiveness by shielding the glucocorticoid
            receptor from degradation.
REFERENCE   4  (bases 1 to 20635)
  AUTHORS   Prasad,R., Zhadanov,A.B., Sedkov,Y., Bullrich,F., Druck,T.,
            Rallapalli,R., Yano,T., Alder,H., Croce,C.M., Huebner,K., Mazo,A.
            and Canaani,E.
  TITLE     Structure and expression pattern of human ALR, a novel gene with
            strong homology to ALL-1 involved in acute leukemia and to
            Drosophila trithorax
  JOURNAL   Oncogene 15 (5), 549-560 (1997)
   PUBMED   9247308
REFERENCE   5  (bases 1 to 20635)
  AUTHORS   Margolis,R.L., Abraham,M.R., Gatchell,S.B., Li,S.H., Kidwai,A.S.,
            Breschel,T.S., Stine,O.C., Callahan,C., McInnis,M.G. and Ross,C.A.
  TITLE     cDNAs with long CAG trinucleotide repeats from human brain
  JOURNAL   Hum Genet 100 (1), 114-122 (1997)
   PUBMED   9225980
REFERENCE   6  (bases 1 to 20635)
  AUTHORS   Imbert,G., Saudou,F., Yvert,G., Devys,D., Trottier,Y.,
            Garnier,J.M., Weber,C., Mandel,J.L., Cancel,G., Abbas,N., Durr,A.,
            Didierjean,O., Stevanin,G., Agid,Y. and Brice,A.
  TITLE     Cloning of the gene for spinocerebellar ataxia 2 reveals a locus
            with high sensitivity to expanded CAG/glutamine repeats
  JOURNAL   Nat Genet 14 (3), 285-291 (1996)
   PUBMED   8896557
REFERENCE   7  (bases 1 to 20635)
  AUTHORS   Jiang,J.X., Deprez,R.H., Zwarthoff,E.C. and Riegman,P.H.
  TITLE     Characterization of four novel CAG repeat-containing cDNAs
  JOURNAL   Genomics 30 (1), 91-93 (1995)
   PUBMED   8595911
REFERENCE   8  (bases 1 to 20635)
  AUTHORS   Adam,M.P., Hudgins,L. and Hannibal,M.
  TITLE     Kabuki Syndrome
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   21882399
REFERENCE   9  (bases 1 to 20635)
  AUTHORS   Tekendo-Ngongang,C., Muenke,M. and Kruszka,P.
  TITLE     Holoprosencephaly Overview
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301702
REFERENCE   10 (bases 1 to 20635)
  AUTHORS   Longoni,M., Pober,B.R. and High,F.A.
  TITLE     Congenital Diaphragmatic Hernia Overview
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301533
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC011603.37.
            This sequence is a reference standard in the RefSeqGene project.
            
            On or before Dec 20, 2019 this sequence version replaced
            XM_005269162.4, NM_003482.3.
            
            Summary: The protein encoded by this gene is a histone
            methyltransferase that methylates the Lys-4 position of histone H3.
            The encoded protein is part of a large protein complex called
            ASCOM, which has been shown to be a transcriptional regulator of
            the beta-globin and estrogen receptor genes. Mutations in this gene
            have been shown to be a cause of Kabuki syndrome. [provided by
            RefSeq, Oct 2010].
            
            CCDS Note: The full-length exon combination of this CCDS
            representation is inferred. It is mostly supported by the mRNA
            AF010403.1, but with correction of a gap in exon 10-11, supported
            by the mRNA AF010404.1, and by EST, RNA-Seq and orthologous
            transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1965299, SAMEA1966682
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000301067.12/ ENSP00000301067.7
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1182              AC011603.37        98124-99305
            1183-1268           AC011603.37        103557-103642
            1269-1395           AC011603.37        103892-104018
            1396-1619           AC011603.37        104167-104390
            1620-1729           AC011603.37        104502-104611
            1730-1892           AC011603.37        104778-104940
            1893-2058           AC011603.37        105277-105442
            2059-2173           AC011603.37        105597-105711
            2174-2331           AC011603.37        105846-106003
            2332-2477           AC011603.37        106209-106354
            2478-4016           AC011603.37        106494-108032
            4017-5125           AC011603.37        108128-109236
            5126-5239           AC011603.37        109700-109813
            5240-5350           AC011603.37        110149-110259
            5351-5455           AC011603.37        110849-110953
            5456-5637           AC011603.37        112128-112309
            5638-5802           AC011603.37        112494-112658
            5803-5912           AC011603.37        112744-112853
            5913-5960           AC011603.37        112951-112998
            5961-6182           AC011603.37        113953-114174
            6183-6302           AC011603.37        114396-114515
            6303-6407           AC011603.37        114614-114718
            6408-6538           AC011603.37        114920-115050
            6539-6686           AC011603.37        115136-115283
            6687-6752           AC011603.37        115490-115555
            6753-6863           AC011603.37        115732-115842
            6864-7001           AC011603.37        116040-116177
            7002-7086           AC011603.37        116273-116357
            7087-7328           AC011603.37        116588-116829
            7329-7402           AC011603.37        116928-117001
            7403-7453           AC011603.37        117213-117263
            7454-9265           AC011603.37        117383-119194
            9266-9448           AC011603.37        119301-119483
            9449-9585           AC011603.37        119560-119696
            9586-11450          AC011603.37        119929-121793
            11451-11574         AC011603.37        123983-124106
            11575-11659         AC011603.37        124252-124336
            11660-11726         AC011603.37        124442-124508
            11727-11959         AC011603.37        124619-124851
            11960-14749         AC011603.37        124954-127743
            14750-14890         AC011603.37        127885-128025
            14891-15058         AC011603.37        128150-128317
            15059-15218         AC011603.37        128479-128638
            15219-15294         AC011603.37        129442-129517
            15295-15470         AC011603.37        129682-129857
            15471-15601         AC011603.37        129960-130090
            15602-15734         AC011603.37        130777-130909
            15735-15862         AC011603.37        130988-131115
            15863-17003         AC011603.37        131596-132736
            17004-17140         AC011603.37        133972-134108
            17141-17271         AC011603.37        134210-134340
            17272-17557         AC011603.37        136043-136328
            17558-17631         AC011603.37        136565-136638
            17632-17740         AC011603.37        136767-136875
            17741-20635         AC011603.37        137046-139940
FEATURES             Location/Qualifiers
     source          1..20635
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q13.12"
     gene            1..20635
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /note="lysine methyltransferase 2D"
                     /db_xref="GeneID:8085"
                     /db_xref="HGNC:HGNC:7133"
                     /db_xref="MIM:602113"
     exon            1..1182
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            1183..1268
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     CDS             1220..17833
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /EC_number="2.1.1.364"
                     /note="trinucleotide repeat containing 21; Kabuki make-up
                     syndrome; histone-lysine N-methyltransferase MLL2;
                     ALL1-related protein; lysine (K)-specific
                     methyltransferase 2D; lysine N-methyltransferase 2D;
                     myeloid/lymphoid or mixed-lineage leukemia 2"
                     /codon_start=1
                     /product="histone-lysine N-methyltransferase 2D"
                     /protein_id="NP_003473.3"
                     /db_xref="CCDS:CCDS44873.1"
                     /db_xref="GeneID:8085"
                     /db_xref="HGNC:HGNC:7133"
                     /db_xref="MIM:602113"
                     /translation="MDSQKLAGEDKDSEPAADGPAASEDPSATESDLPNPHVGEVSVL
                     SSGSPRLQETPQDCSGGPVRRCALCNCGEPSLHGQRELRRFELPFDWPRCPVVSPGGS
                     PGPNEAVLPSEDLSQIGFPEGLTPAHLGEPGGSCWAHHWCAAWSAGVWGQEGPELCGV
                     DKAIFSGISQRCSHCTRLGASIPCRSPGCPRLYHFPCATASGSFLSMKTLQLLCPEHS
                     EGAAYLEEARCAVCEGPGELCDLFFCTSCGHHYHGACLDTALTARKRAGWQCPECKVC
                     QACRKPGNDSKMLVCETCDKGYHTFCLKPPMEELPAHSWKCKACRVCRACGAGSAELN
                     PNSEWFENYSLCHRCHKAQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVAC
                     QGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLS
                     PPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPE
                     SSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPP
                     PEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEAS
                     RLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSP
                     PPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEG
                     PHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLS
                     PQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELE
                     KPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEE
                     LPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESP
                     LAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQH
                     SLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEP
                     SATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLAS
                     ELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDI
                     VNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARDEGSLRLCTD
                     SLPETDDSLLCDAGTAISGGKAEGEKGRRRSSPARSRIKQGRSSSFPGRRRPRGGAHG
                     GRGRGRARLKSTASSIETLVVADIDSSPSKEEEEEDDDTMQNTVVLFSNTDKFVLMQD
                     MCVVCGSFGRGAEGHLLACSQCSQCYHPYCVNSKITKVMLLKGWRCVECIVCEVCGQA
                     SDPSRLLLCDDCDISYHTYCLDPPLLTVPKGGWKCKWCVSCMQCGAASPGFHCEWQNS
                     YTHCGPCASLVTCPICHAPYVEEDLLIQCRHCERWMHAGCESLFTEDDVEQAADEGFD
                     CVSCQPYVVKPVAPVAPPELVPMKVKEPEPQYFRFEGVWLTETGMALLRNLTMSPLHK
                     RRQRRGRLGLPGEAGLEGSEPSDALGPDDKKDGDLDTDELLKGEGGVEHMECEIKLEG
                     PVSPDVEPGKEETEESKKRKRKPYRPGIGGFMVRQRKSHTRTKKGPAAQAEVLSGDGQ
                     PDEVIPADLPAEGAVEQSLAEGDEKKKQQRRGRKKSKLEDMFPAYLQEAFFGKELLDL
                     SRKALFAVGVGRPSFGLGTPKAKGDGGSERKELPTSQKGDDGPDIADEESRGLEGKAD
                     TPGPEDGGVKASPVPSDPEKPGTPGEGMLSSDLDRISTEELPKMESKDLQQLFKDVLG
                     SEREQHLGCGTPGLEGSRTPLQRPFLQGGLPLGNLPSSSPMDSYPGLCQSPFLDSRER
                     GGFFSPEPGEPDSPWTGSGGTTPSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQLS
                     TISPVLYANINFPNLKQDYPDWSSRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRIN
                     KVQKQAESQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTP
                     AGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFP
                     TAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPR
                     CPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGF
                     VDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPS
                     HPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQ
                     SPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFK
                     AGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTF
                     PQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGP
                     SSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGS
                     SLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAG
                     AVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDD
                     RLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATS
                     MRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQK
                     GLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNN
                     SLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLPCEDPELDDDFDAHKA
                     LEDDEELAHLGLGVDVAKGDDELGTLENLETNDPHLDDLLNGDEFDLLAYTDPELDTG
                     DKKDIFNEHLRLVESANEKAEREALLRGVEPGPLGPEERPPPAADASEPRLASVLPEV
                     KPKVEEGGRHPSPCQFTIATPKVEPAPAANSLGLGLKPGQSMMGSRDTRMGTGPFSSS
                     GHTAEKASFGATGGPPAHLLTPSPLSGPGGSSLLEKFELESGALTLPGGPAASGDELD
                     KMESSLVASELPLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPA
                     QAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAMV
                     SNQGHMLSGQHGGQAGLVPQQSSQPVLSQKPMGTMPPSMCMKPQQLAMQQQLANSFFP
                     DTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGSIGVAPGMNRQQVSLLAQRLSGGP
                     SSDLQNHVAAGSGQERSAGDPSQPRPNPPTFAQGVINEADQRQYEEWLFHTQQLLQMQ
                     LKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVR
                     KQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHG
                     LQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGG
                     FFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQ
                     QQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQH
                     PGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAG
                     LSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQ
                     LQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQ
                     QQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQG
                     GPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQ
                     VSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLER
                     PMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQ
                     QLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELG
                     AGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQL
                     PPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSL
                     VPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLA
                     GPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKE
                     DAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPA
                     ITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSL
                     PPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPP
                     HNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPVIP
                     LIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVM
                     VAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLK
                     QFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSP
                     PPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDS
                     RPPRLKKWKGVRWKRLRLLLTIQKGSGRQEDEREVAEFMEQLGTALRPDKVPRDMRRC
                     CFCHEEGDGATDGPARLLNLDLDLWVHLNCALWSTEVYETQGGALMNVEVALHRGLLT
                     KCSLCQRTGATSSCNRMRCPNVYHFACAIRAKCMFFKDKTMLCPMHKIKGPCEQELSS
                     FAVFRRVYIERDEVKQIASIIQRGERLHMFRVGGLVFHAIGQLLPHQMADFHSATALY
                     PVGYEATRIYWSLRTNNRRCCYRCSIGENNGRPEFVIKVIEQGLEDLVFTDASPQAVW
                     NRIIEPVAAMRKEADMLRLFPEYLKGEELFGLTVHAVLRIAESLPGVESCQNYLFRYG
                     RHPLMELPLMINPTGCARSEPKILTHYKRPHTLNSTSMSKAYQSTFTGETNTPYSKQF
                     VHSKSSQYRRLRTEWKNNVYLARSRIQGLGLYAAKDLEKHTMVIEYIGTIIRNEVANR
                     REKIYEEQNRGIYMFRINNEHVIDATLTGGPARYINHSCAPNCVAEVVTFDKEDKIII
                     ISSRRIPKGEELTYDYQFDFEDDQHKIPCHCGAWNCRKWMN"
     exon            1269..1395
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            1396..1619
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            1620..1729
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            1730..1892
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            1893..2058
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            2059..2173
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            2174..2331
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            2332..2477
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            2478..4016
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            4017..5125
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            5126..5239
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            5240..5350
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            5351..5455
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            5456..5637
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            5638..5802
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            5803..5912
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            5913..5960
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            5961..6182
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            6183..6302
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            6303..6407
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            6408..6538
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            6539..6686
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            6687..6752
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            6753..6863
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            6864..7001
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            7002..7086
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            7087..7328
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            7329..7402
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            7403..7453
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            7454..9265
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            9266..9448
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            9449..9585
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            9586..11450
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            11451..11574
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            11575..11659
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            11660..11726
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            11727..11959
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            11960..14749
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            14750..14890
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            14891..15058
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            15059..15218
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            15219..15294
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            15295..15470
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            15471..15601
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            15602..15734
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            15735..15862
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            15863..17003
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            17004..17140
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            17141..17271
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            17272..17557
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            17558..17631
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            17632..17740
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     exon            17741..20635
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /inference="alignment:Splign:2.1.0"
     regulatory      20355..20360
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /note="hexamer: AATAAA"
     polyA_site      20377
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /note="major polyA site"
     regulatory      20612..20617
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /note="hexamer: AATAAA"
     polyA_site      20635
                     /gene="KMT2D"
                     /gene_synonym="AAD10; ALR; BCAHH; CAGL114; KABUK1; KMS;
                     MLL2; MLL4; TNRC21"
                     /note="major polyA site"
ORIGIN      
        1 gccgctccgc tccaacacaa aatagggccg cctcttctcc tttctccccc tctcgagtgg
       61 ggtgccccgg gcaaaaggcc cccccggatc tagcgccgaa ggcttcacga atcttcacga
      121 ccgctgccca gctcttgggc caggaaatag ccccttcgca ggaaccaccc taccggccga
      181 acaggaggcg gaggggggga ggcggagcgg cgccgcgctg cactactttc ctctccggtt
      241 gcaaatggct gcctcgttcc ccactttccg ctcagtttcc tgaccccccg gtgccgggag
      301 ccggggttgg gccatgcacc tctaggccgc ctgcgatcac agtcagccgg gggtcgaggg
      361 ggtgccaccg accagagccg gccaggccgg gggcggggca gctcccgagg ccagagggga
      421 agggaggcga gcgcagggcc tggagcggcc ggaggggagc gggcagaggg ctcgcaccgc
      481 ccgccccttc cttttcctcg cctacctagc ctcctccctt ccccgggggg agcagaaggt
      541 ggggggctcg aagccgccga gggtgagcgc tcggggtcga gaagcccggc gctgggtgtg
      601 tgtcaggttc agccccgcgg ccccgccggc cccgcgtcgc cgtagctcgc gcggccccgg
      661 gcgccggccg gggcggggag aggggctcgg cgctcctgcg agggtctcac gttccatccg
      721 ggccaggcgc ggggcggcgc ggcattcctt ccgggctgct ggggaggcgc ctcgacgttc
      781 catctggaga gcctcgacgt tccgcccgag cccggcgcgg gcggccgggg cgctggccgg
      841 gccctaggac tgagaggccg cccggcgacg cggatgcgga gcctgctcgc ccaagatcaa
      901 agccaccggt gctctctttg tgtccgctcg ggattcgccg ccctggggct gtccatggaa
      961 acctaaactg ctggaacctg aggcagagaa cccctctttg gcttcttgct gtttttttgt
     1021 ggggggaggg tggccactcc gacctggatt taccgttctt ggccccccta agcccccccg
     1081 tgcggggggc ggctgtgatc gctctggcgg ttggaggtcg gggagcggcc cgggctctgg
     1141 ccatgttctc ggatgaggat ttctggatcg ccctgtgaag aggtctcccc gagagggccc
     1201 tgcccagtcg gagagaggga tggacagcca gaagctggct ggtgaggata aagattcaga
     1261 accggcagct gatggacctg cagcttctga ggacccaagt gccactgagt cagacctgcc
     1321 caacccacat gtgggagagg tctctgtcct tagttctggg agtcccaggc ttcaggagac
     1381 tcctcaggac tgcagtgggg gtccggtgcg gcgttgtgct ctctgtaact gcggggagcc
     1441 cagtctacac gggcagcggg agctacggcg ctttgagttg ccatttgatt ggccccggtg
     1501 tccagtggtg tcccctgggg ggagcccagg gcccaatgag gcagtgctgc ccagtgagga
     1561 cctatcacag attggtttcc ctgagggcct tacacctgcc cacctaggag aacctggagg
     1621 gtcctgctgg gctcaccatt ggtgtgctgc atggtcggca ggcgtatggg ggcaggaggg
     1681 cccagaacta tgtggtgtgg acaaggccat cttctcaggg atctcacagc gctgctccca
     1741 ctgcaccagg ctcggtgcct ccatcccttg ccgctcacct ggatgtccac ggctttacca
     1801 cttcccctgc gcgactgcca gcggttcctt cctatccatg aaaacactgc agctgctatg
     1861 cccagagcac agtgaggggg ctgcatatct ggaggaggct cgctgtgcag tgtgtgaggg
     1921 gccaggggag ttgtgtgacc tgttcttctg taccagctgt gggcatcact atcacggggc
     1981 ctgcctggac actgctctga ctgcccgcaa acgtgctggc tggcagtgcc ctgaatgcaa
     2041 agtgtgccaa gcctgcagga aacctgggaa tgactctaag atgttggttt gtgagacgtg
     2101 tgacaaagga taccatactt tctgcctaaa accacccatg gaggaactgc ctgctcactc
     2161 ttggaagtgc aaggcgtgcc gggtgtgccg ggcctgtggg gcgggctcag cagaactgaa
     2221 tcccaactcg gagtggtttg agaactactc tctctgtcac cgctgtcaca aagcccaggg
     2281 aggtcagact atccgctccg ttgctgagca gcataccccg gtgtgtagca gattttcacc
     2341 cccagagcct ggcgataccc ccactgacga gcccgatgct ctgtacgttg catgccaagg
     2401 gcagccaaag ggtgggcacg tgacctctat gcaacccaag gaaccagggc ccctgcaatg
     2461 tgaagccaaa ccactaggga aagcaggggt ccaacttgag ccccagttgg aggcccccct
     2521 aaacgaggag atgccactgc tgcccccacc tgaggagtca cccctgtccc caccacctga
     2581 ggaatcaccc acgtccccac cacctgaggc atcacgcctg tcaccaccac ctgaggaatt
     2641 gcccgcatcc ccacttcctg aggcattgca cctgtcccgg ccgctggagg aatcgcccct
     2701 ctctccgccg cctgaggagt ctcctctgtc tcccccacct gaatcatcac ctttttctcc
     2761 actggaggag tcgcccttgt ctccaccgga agagtcaccc ccatctcctg cacttgagac
     2821 gcctctatcc ccaccacctg aagcatcgcc cctgtcccca ccatttgaag aatctccttt
     2881 gtccccgcca cctgaggaat tgcccacttc cccgccacct gaagcatctc gcctgtctcc
     2941 accacctgag gagtcaccca tgtcccctcc acctgaagag tcacccatgt ctccaccacc
     3001 ggaggcatct cgtctgttcc caccatttga agagtctcct ctgtcccctc cacctgagga
     3061 gtctcccctt tccccaccac ctgaggcatc acgcctgtcc ccaccacctg aggactcgcc
     3121 tatgtcccca ccacctgaag aatcacctat gtccccccca cctgaggtat cgcgcctatc
     3181 ccccctgcct gtggtgtcac gcctgtctcc accgcctgag gaatctccct tgtccccacc
     3241 gcctgaggag tctcccacgt cccctccacc tgaggcttca cgcctctccc caccacctga
     3301 ggactccccc acatccccac cacctgagga ctcacctgct tccccaccac cggaggactc
     3361 gctcatgtcc ctgccgctgg aggagtcacc cctgttgcca ctacctgagg agccgcaact
     3421 ctgcccccgg tccgaggggc cgcacctgtc accccggcct gaggagccgc acctgtcccc
     3481 ccggcctgag gagccacacc tatctccgca ggctgaggag ccacacctgt ccccccagcc
     3541 tgaggagcca tgcctatgcg ctgtgcctga ggagccacac ttgtcccccc aggctgaggg
     3601 accacatctg tcccctcagc ctgaggaatt gcacctgtcc ccccagactg aggagccgca
     3661 cctgtctcct gtgcctgagg agccatgctt gtccccccaa cctgaggaat cacacctgtc
     3721 cccccagtct gaggagccat gcctgtcccc ccggcctgag gaatcgcatc tgtcccctga
     3781 gcttgagaag ccacccctgt cccctcggcc tgaaaagccc cctgaggagc caggccaatg
     3841 ccctgcacct gaggagctgc ccttgttccc tccccctggg gaaccatcct tatctccctt
     3901 gcttggagag ccagccctgt ctgagcctgg ggaaccacct ctgtcccctc tgcccgagga
     3961 gctgccgttg tccccatctg gggagccatc cttgtcgcct cagctgatgc caccagatcc
     4021 ccttcctcct ccactctcac ccatcatcac agctgcggcc ccaccggccc tgtctccttt
     4081 gggggagtta gagtacccct ttggtgccaa aggggacagt gaccctgagt caccgttggc
     4141 tgcccccatc ctggagacac ccatcagccc tccaccagaa gctaactgca ctgaccctga
     4201 gcctgtcccc cctatgatcc ttcccccatc tccaggctcc ccagtggggc cggcttctcc
     4261 catcctgatg gagccccttc ctcctcagtg ttcgccactc cttcagcatt ccctggttcc
     4321 ccaaaactcc cctccttccc agtgctctcc tcctgcccta ccactgtccg ttccctcccc
     4381 gttgagtccc atagggaagg tagtgggggt ctcagatgag gctgagctgc acgagatgga
     4441 gactgagaaa gtttcagaac ctgaatgccc agccttggaa cccagtgcca ccagtcctct
     4501 cccttcccca atgggggacc tttcctgccc cgcccccagc cctgccccag ccctggatga
     4561 cttctctggc ctaggggaag acacagcccc tctggatggg attgatgctc cgggttcaca
     4621 gccagagcct ggacagaccc ctggcagttt ggctagtgaa cttaaaggct cccctgtgct
     4681 cctggacccc gaggagctgg cccctgtgac ccctatggag gtctaccccg aatgcaagca
     4741 gacagcaggg cagggctcac catgtgaaga acaggaagag ccacgtgcac cggtggcccc
     4801 cacaccaccc actctcatca aatccgacat cgttaacgag atctctaatc tgagccaggg
     4861 tgatgccagt gccagttttc ctggctcaga gcccctcctg ggctctccag acccggaggg
     4921 gggtggctcc ctgtccatgg agttgggggt ctctacggat gttagtccag cccgagatga
     4981 gggctcccta cggctctgta ctgactcact gccagagact gatgactcac tattgtgcga
     5041 tgctgggaca gctatcagcg gaggcaaagc tgagggggag aaggggcggc ggcgcagctc
     5101 cccagcccgt tcccgcatca aacagggtcg cagcagcagt ttcccaggaa gacgccggcc
     5161 tcgtggagga gcccatggag gacgtggtag aggacgggcc cggctaaagt caactgcttc
     5221 ttccattgag actctggtag ttgctgacat tgatagctct cccagtaagg aggaggagga
     5281 agaagatgat gacaccatgc agaataccgt ggttctcttc tccaacacag acaaatttgt
     5341 cctaatgcag gacatgtgtg tggtatgtgg cagctttggc cggggggcag agggccacct
     5401 ccttgcctgt tcgcagtgct ctcagtgcta tcacccttac tgtgtcaaca gcaagatcac
     5461 caaggtgatg ctgctcaagg gctggcgttg tgtggagtgt attgtgtgtg aggtgtgtgg
     5521 ccaggcctcc gacccctcac gcctgctgct ctgtgatgac tgtgatatta gctaccacac
     5581 atactgcctg gaccccccac tgctcaccgt ccccaagggc ggctggaagt gcaagtggtg
     5641 tgtgtcctgt atgcagtgtg gggctgcttc ccctggcttc cactgtgaat ggcagaatag
     5701 ttacacacac tgtgggccct gtgccagcct ggtgacctgc cctatctgtc atgctcctta
     5761 cgtagaagag gacctactaa tccagtgccg ccactgtgaa cggtggatgc atgcaggctg
     5821 tgagagcctc ttcacagagg acgatgtgga gcaggcagcc gatgaaggct ttgactgtgt
     5881 ctcctgccag ccctacgtgg taaagcctgt ggcgcctgtt gcacctccag agctggtgcc
     5941 catgaaggtg aaagagccag agccccagta ctttcgcttc gaaggtgtgt ggctgacaga
     6001 aactggcatg gccttgctgc gtaacctgac catgtcacca ctgcacaagc ggcgccaacg
     6061 gcgaggacgg cttggcctcc caggcgaggc aggattggag ggttctgagc cctcagatgc
     6121 ccttggccct gatgacaaga aggatgggga cctggacacc gatgagctgc tcaagggtga
     6181 aggtggtgtg gagcacatgg agtgcgaaat taaactggag ggccccgtca gccctgatgt
     6241 ggagcctggc aaagaggaga ccgaggaaag caaaaaacgc aagcgtaaac catatcggcc
     6301 tggcattggt ggtttcatgg tgcgacagcg gaaatcccac acacgcacga aaaaggggcc
     6361 tgctgcacag gcggaggtgt tgagtgggga tgggcagccc gacgaggtga tacctgctga
     6421 cctgcctgca gagggcgccg tggagcagag cttagctgaa ggggatgaga agaagaagca
     6481 acagcggcga gggcgcaaga agagcaaact ggaggacatg ttccctgctt acttgcagga
     6541 agccttcttt gggaaggagc tgctggacct gagccgtaag gccctttttg cagttggggt
     6601 gggccggcca agctttggac tagggacccc aaaagccaag ggagatggag gctcagaaag
     6661 gaaggaactc cccacatcgc agaaaggaga tgatggtcca gatattgcag atgaagaatc
     6721 ccgtggcctc gagggcaaag ccgatacacc aggacctgag gatgggggcg tgaaggcatc
     6781 cccagtgccc agtgaccctg agaagccagg caccccaggt gaagggatgc ttagctctga
     6841 cttagacagg atttccacag aagaactgcc caagatggaa tccaaggacc tgcagcagct
     6901 cttcaaggat gttctgggct ctgaacgaga acagcatctg ggttgtggaa cccctggcct
     6961 agaaggcagc cgtacgccac tgcagaggcc ctttcttcaa ggtggactcc ctttgggcaa
     7021 tctgccctcc agcagcccaa tggactccta cccaggcctc tgccagtccc cgttcctgga
     7081 ttctagggag cgcgggggct tctttagccc ggaacccggt gagcccgaca gcccctggac
     7141 gggctcaggt ggcaccacgc cctccacccc cacaaccccc accacggagg gtgagggcga
     7201 cggactctcc tataaccagc ggagtcttca gcgctgggag aaggatgagg agttgggcca
     7261 gctgtccacc atctcacctg tgctctatgc caacattaat tttcctaatc tcaagcaaga
     7321 ctacccagac tggtcaagcc gttgcaaaca aatcatgaag ctctggagaa aggttccagc
     7381 agctgacaaa gccccctacc tgcaaaaggc caaagataac cgggcagctc accgcatcaa
     7441 caaggtgcag aagcaggctg agagccagat caacaagcag accaaggtgg gcgacatagc
     7501 ccgtaagact gaccgaccgg ccctacatct ccgcattccc ccgcagccag gggcactggg
     7561 cagcccgccc cccgctgctg cccccaccat tttcattggc agccccacta cccccgccgg
     7621 cttgtctacc tctgcggacg ggttcctgaa gccgccggcg ggctcggtgc ctggccctga
     7681 ctcgcctggt gagctcttcc tcaagctccc accccaggtg cccgcccaag tgccttcgca
     7741 ggaccccttt ggactggccc ctgcctatcc cctggagccc cgcttcccca cggcaccgcc
     7801 cacctatccc ccctatccta gtcctacggg ggcccctgcg cagcccccga tgctgggcgc
     7861 ctcatctcgt cctggggctg gccagccagg ggaattccac actaccccac ctggcacccc
     7921 cagacaccag ccctccacac ctgacccatt cctcaaaccc cgctgcccct cgctggataa
     7981 cttggctgtg cctgagagcc ctggggtagg gggaggcaaa gcttccgagc ccctgctctc
     8041 gcccccacct tttggggagt cccggaaggc cctagaggtg aagaaggaag agcttggggc
     8101 atcctctcct agctatgggc ccccaaacct gggctttgtt gactcaccct cctcaggcac
     8161 ccacctgggt ggcctggagt taaagacacc tgatgtcttc aaagcccccc tgacccctcg
     8221 ggcatctcag gtagagcccc agagcccggg cttgggccta aggccccagg agccaccccc
     8281 tgcccaggct ttggcacctt ctcctccaag tcacccagac atctttcgcc ctggctccta
     8341 cactgaccca tatgctcagc ccccattgac tcctcggccc caacctccgc cccctgagag
     8401 ctgctgtgct ctgccccctc gctcactgcc ctccgaccct ttctcccgag tgcctgccag
     8461 tcctcagtcc cagtccagct cccagtctcc actgacaccc cggcctctgt ctgctgaagc
     8521 tttttgccca tcacccgtta cccctcgctt ccagtcccct gacccttatt ctcgcccacc
     8581 ctcacgccct cagtcccgtg acccatttgc cccattgcat aagccacccc gaccccagcc
     8641 ccctgaagtt gcctttaagg ctgggtctct agcccacact tcgctggggg ctggggggtt
     8701 cccagcagcc ctgcccgcgg ggccagcagg tgagctccat gccaaggtcc caagtgggca
     8761 gccccccaat tttgtccggt cccctgggac gggtgcattt gtgggcaccc cctctcccat
     8821 gcgtttcact ttccctcagg cagtagggga gccttcccta aagccccctg tccctcagcc
     8881 tggtctcccg ccaccccatg ggatcaacag ccattttggg cccggcccca ccttgggcaa
     8941 gcctcaaagc acaaactaca cagtagccac agggaacttc cacccatcgg gcagccccct
     9001 ggggcccagc agcgggtcca caggggagag ctatgggctg tccccactac gccctccgtc
     9061 ggttctgcca ccacctgcac ccgacggatc cctcccctac ctgtcccatg gagcctcaca
     9121 gcgatcaggc atcacctctc ctgtcgaaaa gcgagaagac ccagggactg gaatgggtag
     9181 ctctttggcg acagctgaac tcccaggtac ccaggaccca ggcatgtccg gccttagcca
     9241 aacagagctg gagaagcaac ggcagcgcca gcgactacga gagctgctga ttcggcagca
     9301 gatccagcgc aacaccctgc ggcaggagaa ggaaacagct gcagcagctg caggagcagt
     9361 ggggcctcca ggcagctggg gtgctgagcc cagcagccct gcctttgagc agctgagtcg
     9421 aggccagacc ccctttgctg ggacacagga caagagcagc cttgtggggt tgcccccaag
     9481 caagctgagt ggccccatcc tggggccagg gtccttccct agcgatgacc gactctcccg
     9541 gccacctcca ccagccacgc cttcctctat ggatgtgaac agccggcaac tggtaggagg
     9601 ctcccaagct ttctatcagc gagcacccta tcctgggtcc ctgcccttac agcagcaaca
     9661 gcaacaactg tggcagcaac aacaggcaac agcagcaacc tccatgcgat ttgccatgtc
     9721 agctcgcttt ccatcaactc ctggacctga acttggccgc caagccctag gttccccgtt
     9781 ggcgggaatt tccacccgtc tgccaggccc tggtgagcca gtgcctggtc cagctggtcc
     9841 tgcccagttc attgagctgc ggcacaatgt acagaaagga ctgggacctg ggggcactcc
     9901 gtttcctggt cagggcccac ctcagagacc ccgtttttac cctgtaagtg aggaccccca
     9961 ccgactggct cctgaagggc ttcggggcct ggcggtatca ggtcttcccc cacagaaacc
    10021 ctcagcccca ccggcccctg aattgaacaa cagtcttcat ccaacacccc acaccaaggg
    10081 tcctaccctg ccaactggtt tggagctggt caaccggccc ccgtcgagca ctgagcttgg
    10141 ccgccccaat cctctggccc tggaagctgg gaagttgccc tgtgaggatc ccgagctgga
    10201 tgacgatttt gatgcccaca aggccctaga ggatgatgaa gagcttgctc acctgggtct
    10261 gggtgtggat gtggccaagg gtgatgatga acttggcacc ttagaaaacc tggagaccaa
    10321 tgacccccac ttggatgacc tgctcaatgg agacgagttt gacctgctgg catatactga
    10381 tcctgagctg gacactgggg acaagaagga tatcttcaat gagcacctga ggctggtaga
    10441 atcggctaat gagaaggctg aacgggaggc cctgctgcgg ggggtggagc caggaccctt
    10501 gggccctgag gagcgccctc cccctgctgc tgatgcctct gaaccccgcc tggcatctgt
    10561 gctccctgag gtgaagccca aggtggagga gggtggacgc cacccttctc cttgccaatt
    10621 caccattgct acccccaagg tagagcccgc acctgctgcc aattcccttg gcctggggct
    10681 aaagccagga cagagcatga tgggcagccg ggatacccgg atgggcacag ggccattttc
    10741 tagcagtggg cacacagctg agaaggcctc ctttggggcc acgggaggac caccagctca
    10801 cctgctgacc cccagcccac tgagtggccc aggaggatcc tccctgctgg aaaagtttga
    10861 gctcgagagt ggggctttga ccttgcctgg tggacctgca gcatctgggg atgagctaga
    10921 caagatggag agctcactgg tagccagcga gttacccctg ctcattgagg acctgttgga
    10981 gcatgagaag aaggagctgc agaagaagca gcagctttca gcacagttgc agcctgccca
    11041 gcagcagcag caacagcagc agcagcattc cctactgtct gcaccaggcc ctgcccaggc
    11101 catgtctttg ccacatgagg gctcttctcc cagtttggct gggtcccaac agcagctttc
    11161 cctgggtctt gcaggtgccc gacagccagg tttgccccag ccactgatgc ccacccagcc
    11221 accagctcat gccctccagc aacgcctggc tccatccatg gctatggtgt ccaatcaagg
    11281 gcatatgcta agtgggcagc atggagggca ggcaggcttg gtaccccagc agagctcaca
    11341 gccagtgcta tcacagaagc ccatgggcac catgccacct tccatgtgca tgaagccgca
    11401 gcaattggca atgcagcagc agctggcaaa cagcttcttc ccagatacag acctggacaa
    11461 atttgctgca gaagatatca ttgatcccat tgcaaaggcc aagatggtgg ctttgaaagg
    11521 catcaagaaa gtgatggctc agggcagcat tggggtggca cctggtatga acagacagca
    11581 agtgtctctg ctagcccaga ggctctcggg gggacctagc agtgatctgc agaaccatgt
    11641 ggcagctggg agtggccagg agcggagtgc tggtgatccc tcccagcctc gtcccaaccc
    11701 gcccactttt gctcagggag tgatcaatga agctgaccag cggcagtatg aggagtggct
    11761 gttccatacc cagcagctcc tacagatgca gctgaaggtg ctagaggagc agattggtgt
    11821 acaccgcaag tcccggaagg ctctgtgtgc caagcagcgc actgccaaaa aagctggccg
    11881 tgagttccca gaagctgatg ctgagaagct caagctggtt acagagcagc agagcaagat
    11941 ccagaaacaa ctggatcagg tccggaaaca gcagaaggag cacactaatc tcatggcaga
    12001 atatcggaac aagcagcagc aacaacagca gcagcagcag caacaacagc aacagcactc
    12061 agctgtgctg gctctcagcc cttcccagag tccccggctg ctcaccaagc tccctggtca
    12121 gctgctccct ggccatgggc tgcagccacc acaggggcct ccgggtgggc aagccggagg
    12181 tcttcgcctg acccctgggg gtatggcact acctggacag cctggtggcc ccttccttaa
    12241 tacagctctg gcccaacagc agcaacagca acattctggt ggggctggat ccctggctgg
    12301 cccttcaggg ggcttcttcc ctggcaacct tgctcttcga agcctcggac ctgattcaag
    12361 gcttttacag gaaaggcagc tgcagctgca gcagcaacgt atgcagctgg cccagaaact
    12421 gcagcagcag cagcagcagc aacagcagca gcagcacctt ctaggacagg tggcaatcca
    12481 gcagcaacag cagcagggtc ctggagtaca gacaaaccaa gctctgggtc ccaagcccca
    12541 gggccttatg cctcccagca gccaccaagg cctcctggtc cagcagctgt cccctcaacc
    12601 accccagggg ccccagggca tgctgggccc tgcccaggtg gctgtgttgc agcagcagca
    12661 ccctggagct ttgggccccc agggccctca cagacaggtg cttatgaccc agtcccgggt
    12721 gctcagttcc ccccagctgg cacagcaggg tcagggcctt atgggacaca ggctggtcac
    12781 agcccagcag cagcagcagc aacaacagca ccaacagcaa gggtccatgg cagggctgtc
    12841 ccatcttcag cagagtctga tgtcacacag tgggcagccc aaactgagcg ctcagcccat
    12901 gggctcttta cagcagcttc agcagcagca gcagctgcaa cagcaacagc aacttcagca
    12961 gcagcagcag cagcagctac aacagcaaca gcaacttcag cagcaacagc ttcaacagca
    13021 gcaacagcag cagcagcttc aacaacagca gcagcaacag cttcaacagc agcaacagca
    13081 gctacaacag caacagcaac aacaacagca gcagtttcaa cagcagcagc aacagcagca
    13141 gatgggcctt ttaaaccaga gtcgaacttt actgtctcct cagcaacaac agcagcagca
    13201 agtggcactt ggccctggca tgccagcaaa gcctcttcaa cacttttcta gccctggagc
    13261 cctgggtcca accctcctcc tgacgggcaa ggaacaaaac accgtagacc cagccgtttc
    13321 ttcagaggcc actgaggggc cctctacaca tcagggaggg ccgttagcaa taggaactac
    13381 ccctgagtca atggccactg aaccaggaga ggtaaagccc tcactctctg gggactcaca
    13441 actcctgctt gtccaacccc agccccagcc tcagcccagc tctctgcagc tgcagccacc
    13501 tctgaggctt ccaggacaac agcagcagca agttagcctg ctccacacag caggtggagg
    13561 aagccatggg cagctaggca gtggatcatc ttctgaggcc tcatctgtgc cccacctgct
    13621 ggctcagccc tctgtttcct taggggatca gcctgggtcc atgacccaga accttctggg
    13681 cccccaacag cccatgctag agcggcccat gcaaaataat acagggccac aacctcccaa
    13741 accaggacct gtcctccagt ctgggcaggg tctgcctggg gttggaatca tgcctacggt
    13801 gggtcagctt cgagcacagc tccaaggagt cctggccaaa aacccacagc tgcggcactt
    13861 aagtcctcag cagcagcagc agctacaggc actcctcatg cagcggcagc tgcagcagag
    13921 tcaggcagta cgccagaccc caccctacca ggagcctggg acccagacct ctcccctcca
    13981 gggcctcctg ggctgccaac ctcaacttgg gggcttccct ggaccacaga caggccccct
    14041 ccaggagcta ggggcagggc ctcgacctca gggcccaccc cggctccctg ccccaccagg
    14101 agccttatct acaggaccag tccttggccc tgtccatccc acacctccac catccagccc
    14161 tcaagagcca aagagacctt cacaattacc ttcccccagc tcccagcttc ccactgaggc
    14221 ccagctccct cccacccatc cagggacccc caaacctcag gggccaacct tggagccgcc
    14281 tcctgggagg gtctcacctg ctgctgccca gcttgcagat accttgttta gcaagggtct
    14341 gggaccttgg gatcccccag acaacctagc agaaacccag aagccagagc agagcagcct
    14401 ggtacctggg catctggacc aggtgaatgg acaggtggtg cctgaggcat cccaactcag
    14461 catcaagcag gaacctcggg aagagccatg tgccctggga gcccagtcag tgaagaggga
    14521 ggccaatggg gagccaatag gggcaccagg aaccagcaac cacctcctgc tggcaggccc
    14581 tcgctcagaa gctgggcatc tgctcttgca gaagctactc cgggcaaaga atgtgcaact
    14641 cagcactggg cgggggtccg aggggctgcg agctgagatc aacgggcaca ttgacagcaa
    14701 gctggctggg ctggagcaga aactacaggg tacccccagc aacaaggagg atgcagcagc
    14761 aaggaagcct ttgacaccga agcccaagcg ggtacagaag gcaagcgaca ggttggtgag
    14821 ctcccgaaag aagctgcgga aggaggacgg ggtcagggcc agcgaggcct tgctgaaaca
    14881 gctgaaacag gagctgtccc tgctgcccct aacggagcct gctatcaccg ccaattttag
    14941 cctctttgcc ccctttggca gtggctgccc agtcaatggg cagagccagc tgaggggggc
    15001 ctttggaagt ggggcgctgc ccactggccc tgactactat tcccagctgc ttaccaagaa
    15061 taacctgagt aacccgccga caccaccctc gtcgctgccc cccaccccac ccccatcggt
    15121 gcagcagaag atggtgaatg gcgtcacccc atctgaagag ctgggggagc accccaagga
    15181 tgctgcctct gcccgggata gtgaaagggc actgagggat acttcagagg tgaagagtct
    15241 agacctgctg gctgccttgc ctacaccccc tcacaatcag actgaggatg tcaggatgga
    15301 gagtgatgag gatagcgatt ctcctgacag cattgtgcca gcttcatccc ctgagagcat
    15361 cttgggggag gaggcccctc gtttccctca tctgggctca ggccggtggg agcaagagga
    15421 ccgggccctc tcccctgtca tccccctcat tcctcgggcc agcatcccag tcttcccaga
    15481 taccaaacct tatggggccc ttggcctgga ggtccctgga aagctgcctg tcacaacttg
    15541 ggaaaagggc aaaggaagtg aggtgtcagt catgctcaca gtctctgctg ctgcagccaa
    15601 gaacctgaat ggcgtgatgg tggcagtggc ggagctgctg agcatgaaga tccccaactc
    15661 ctatgaggtg ctgttcccag agagccccgc ccgggcaggc actgagccaa agaaggggga
    15721 agctgagggt cctggtggga aggaaaaggg tctggaaggc aagagcccag acactggccc
    15781 tgattggctg aagcagtttg atgcagtgtt gcctggctat accctgaaga gccaactaga
    15841 catcttgagc ctcctgaaac aggagagccc cgccccagag ccacccactc agcacagcta
    15901 tacctacaat gtctccaatc tggatgtgcg acagctctcg gccccacctc ctgaagaacc
    15961 ctccccgccc ccttccccct tggcaccttc tcctgccagt ccccctactg agcccttggt
    16021 tgaacttccc accgaaccct tggctgagcc acccgtcccc tcacctctgc cactggcctc
    16081 atcccctgaa tcagcccgac ccaagccccg tgcccggccc cctgaagaag gtgaagattc
    16141 ccgtcctcct cgcctcaaga aatggaaagg agtgcgctgg aagcggcttc ggctgctgct
    16201 gaccatccag aagggcagtg ggcggcagga ggatgagcgg gaagtggcag agtttatgga
    16261 gcagcttggc acagccttgc gacctgacaa ggtaccgcga gacatgcgtc gctgctgttt
    16321 ctgtcatgag gagggtgacg gggccactga tgggcctgcc cgtctgctga acctggacct
    16381 ggacctgtgg gtgcacctca actgtgccct ttggtccacg gaggtgtatg agacccaggg
    16441 cggggcactg atgaatgtgg aggttgccct gcaccgagga ctgctaacca agtgctccct
    16501 gtgccagcga actggtgcca ccagcagctg caatcgcatg cgttgcccca atgtctacca
    16561 ttttgcttgt gccatccgtg ccaagtgcat gttcttcaag gacaagacca tgctgtgtcc
    16621 aatgcataag atcaaggggc cctgtgagca agagctgagc tcttttgctg tcttccggcg
    16681 ggtctacatt gagcgggacg aggtgaagca aatcgctagc atcattcagc ggggagaacg
    16741 gctgcacatg ttccgtgtgg ggggccttgt gttccacgcc atcggacagc tgctgcctca
    16801 ccagatggct gactttcata gtgccactgc cctctatccc gtgggctacg aggccacgcg
    16861 catctattgg agcctccgca ccaacaatcg tcgctgctgc tatcgctgtt ctattggtga
    16921 gaacaacggg cggccggagt ttgtaatcaa agtcatcgag cagggcctgg aggacctggt
    16981 cttcactgac gcctctcccc aggccgtgtg gaatcgcatc attgagcctg tggctgccat
    17041 gagaaaagag gctgacatgc tgcgactctt ccctgagtat ctgaagggcg aggagctctt
    17101 tgggctgacg gtgcatgccg tgcttcgcat agctgaatca ctgcccgggg tggagagctg
    17161 tcaaaactat ttattccgct atgggcgcca cccccttatg gagctgccac tcatgatcaa
    17221 ccccactggc tgtgcccgat cagagcctaa aatcctcaca cactacaaac ggccccatac
    17281 cctgaacagc accagcatgt ctaaggcata tcagagcacc ttcacaggcg agaccaacac
    17341 cccctacagc aagcagtttg tgcactccaa gtcatctcag taccggcggc tgcgcaccga
    17401 atggaagaac aacgtgtacc tggctcgctc ccgtatccag ggcctggggc tctatgcagc
    17461 caaggaccta gaaaagcaca caatggttat cgagtacatt ggcaccatca ttcggaacga
    17521 ggtggccaac cggcgggaga aaatctacga agagcagaat cgaggcatct acatgttccg
    17581 aataaacaat gaacatgtga ttgatgctac gttgaccggc ggccctgcca ggtacattaa
    17641 ccattcctgt gcccctaact gtgtggccga agtcgtgaca tttgacaaag aggacaaaat
    17701 catcatcatc tccagccggc gaatccccaa aggagaggag ctaacctatg actatcagtt
    17761 tgattttgag gacgatcagc acaagatccc ctgccactgt ggagcctgga attgtcggaa
    17821 atggatgaac taagaagctt tgaggctacc aggcagggga gtccccctac ccacaacctc
    17881 ttccctgaaa gggatgaggg ggaagagagg tagcagccag agccaggacc cagggttggg
    17941 gctgccggct gacccggagc ccctggagca ggaggctggg gcagagggcc ctaggccaag
    18001 cccaccctgg gcaccaggga caatcctctt ccccaccacc ggccctcagg ctggcatctc
    18061 tgcccccagc tccaggaggg gccagacaga agcagccatt gggcatctca ggtttgaggg
    18121 ggatatgggc cgggaactac ccagaagcat ctgggaggca gcagggtggg ggaagaggat
    18181 gtgtggccgg gcctcacagc cctgctgctc ccactgacct ctccggccca actcacggct
    18241 gcaaagagac ttgactaagc ttgacaatcc caaaggccgg gtcccacacc tggccctgcc
    18301 tgccgggtcc tgcccccacc ctcaccccca tccccctccc tcttgatctg tctctgtttc
    18361 cctcttttcc tctgtgtttc tgtctctcta tgggttgtgt ttccttgttt tccactctga
    18421 caaatgcaac atgaacggga aagaggcgcc cagctgccta ggagggcaag ctgggcaagc
    18481 cgggcaagga gaccccgcac ccacacctac ctcatttaag tgttggattt tttgctgttt
    18541 tgaaatgtga gaccctctcc aagcccccta ctgccccaac cctctccccc acctcactgc
    18601 cctcttctga gtgggtggaa ggggggtagg aggaggaaga aaaacaacaa caaaaaatcc
    18661 atctttgttt ttaattatgg gcatgggatg gtggttgagg caaatgatga tgaagattgg
    18721 ggatgactgg cccctagttg ctctaggact tccttctcca tctggacatg ggggcaggag
    18781 ggagctaaac ctaggaccag gatatctccc tcctgttttc ccaacctcat catgagcctg
    18841 tttgccctcc agcccctgga cgggttgggt ggggggtagg gtgagggcta tccctgagtg
    18901 gcatgcccat acctagtgag gcagggtgtg gcccggagct cccactttcc ctcagtcacc
    18961 aaactgctgc tggtctggtg ggaaggggtg gtgatgtggg ggtgggggag cttagtgtca
    19021 gcgcggggag ggtggggggt atttatctat ttatacatgg gattgtacat agtcttgtgg
    19081 ggcatggggg agccggctgg aggtgagaac cctcccctct ccccccaccc cccggggaga
    19141 gcaaatgtaa aactactaat ttttgtgctt tatatattct atataaatat atctattttc
    19201 tttttacaaa accagtttat aaatggtagg ggggtgtggg gcggacacat ggagctcccc
    19261 ttgtgggggg gccccctcca ttacccgacc taccgccctt ttcctcaccc cccaccccac
    19321 tccccacccc ctggctgtga ctgctgtaag atgggggtat agaggctggg caattcccac
    19381 cccctgttgt atagttggac tatgttataa cgcacaaaag agagctgacc ccagggggag
    19441 ccagagggtg atgggttcct tgcctccctt tccttcccct ttctgcccaa gcttgtgctg
    19501 cagttgaacc tcttcctggg ggtgggagta ggtaaggggt gggtgaggcc ccaaacccct
    19561 ctctggtagg gaaccgtggg gatgaagatg aagcttatat gcagttctct tctaggggct
    19621 gtgggcaaag ggcattttgt aattaatatt ttcaagaatc agatgtctgg agtgtagggg
    19681 tgggcttggt ggtggtggac gggcgggcct gctggagggg gagcttggtc gctgttgtga
    19741 ttttaggttt gtttttgttt tgttttgaat ttggggggtt gtggattgtt gggggtaggg
    19801 agattttttt tttttaaagc tgcttcctca actgtttcaa gctgcaaatg tttaagagaa
    19861 taacagcccc cactcccaca ggaaccgctg taattaaatc agacagtagg aagactgggc
    19921 tgctgccctc aaagccacag cccttggatg ttccttttcc gagagcagaa ggtctaggct
    19981 acagggaggg ggagattggc tcccgtgagt caggctgtgt ttggggcttg ggccctggga
    20041 ttgggaaaag gggatggggc agactttgta agcatatgct aggtatccga tagtcctgta
    20101 gaatttagtg aagaaacctt atacagtttt taatttttat ataaactata actcagaccc
    20161 aagctacaag gttggaattt tggttggttt tttttttaag taccctgcct gtataattgc
    20221 atcagaatcc cccaccccac cccccgcccc cgtgtttgta ttttgggttg gtttacactc
    20281 gcacatactc agttttcagt tttccccttt acagtcttct cccctcacct ccaggaccct
    20341 cccccttttt aaaaaataaa tcgctgacaa gtgtgaatcc cgtgaagact ttattttgtg
    20401 ttgtgtgtat cctgtacagc aaggttggtc cttcgtaaca acggatgaaa tggttccctt
    20461 ttttaaagcg ccctctctcc ctccaccctc agcgcccctg tccttggcat gttttgtatc
    20521 agcgatcatt ctgaactgta catatttatg ttgcgagagg caaagggcaa gttttggatt
    20581 ttgcttcttc caagtttgtt tttaaacgac aaataaaaaa agaacatttt aaata
//
