LOCUS       NM_003709               8365 bp    mRNA    linear   PRI 15-OCT-2024
DEFINITION  Homo sapiens KLF transcription factor 7 (KLF7), transcript variant
            1, mRNA.
ACCESSION   NM_003709
VERSION     NM_003709.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 8365)
  AUTHORS   Zhang,J., Li,Z., Han,J., Tian,Z., Meng,Q. and Niu,W.
  TITLE     KLF7 enhances the invasion and migration of colorectal cancer cells
            via the miR-139-5p/TPD52 axis
  JOURNAL   Cancer Biol Ther 25 (1), 2385172 (2024)
   PUBMED   39097779
  REMARK    GeneRIF: KLF7 enhances the invasion and migration of colorectal
            cancer cells via the miR-139-5p/TPD52 axis.
REFERENCE   2  (bases 1 to 8365)
  AUTHORS   Josefson,J.L., Kuang,A., Allard,C., Bianco,M.E., Lowe,W. Jr.,
            Scholtens,D.M., Bouchard,L. and Hivert,M.F.
  TITLE     Newborn adiposity is associated with cord blood DNA methylation at
            IGF1R and KLF7
  JOURNAL   Obesity (Silver Spring) 32 (10), 1923-1933 (2024)
   PUBMED   39165088
  REMARK    GeneRIF: Newborn adiposity is associated with cord blood DNA
            methylation at IGF1R and KLF7.
REFERENCE   3  (bases 1 to 8365)
  AUTHORS   Qiao,S., Jia,Y., Xie,L., Jing,W., Xia,Y., Song,Y., Zhang,J.,
            Cao,T., Song,H., Meng,L., Shi,L. and Zhang,X.
  TITLE     KLF7 promotes neuroblastoma differentiation through the GTPase
            signaling pathway by upregulating neuroblast
            differentiation-associated protein AHNAKs and
            glycerophosphodiesterase GDPD5
  JOURNAL   FEBS J 291 (17), 3870-3888 (2024)
   PUBMED   38924469
  REMARK    GeneRIF: KLF7 promotes neuroblastoma differentiation through the
            GTPase signaling pathway by upregulating neuroblast
            differentiation-associated protein AHNAKs and
            glycerophosphodiesterase GDPD5.
REFERENCE   4  (bases 1 to 8365)
  AUTHORS   Li,Y. and Liu,L.
  TITLE     UKLF/PCBP2 axis governs the colorectal cancer development by
            transcriptionally activating SLC39A4
  JOURNAL   Biochim Biophys Acta Mol Cell Res 1871 (6), 119755 (2024)
   PUBMED   38768927
  REMARK    GeneRIF: UKLF/PCBP2 axis governs the colorectal cancer development
            by transcriptionally activating SLC39A4.
REFERENCE   5  (bases 1 to 8365)
  AUTHORS   Kawamura,Y., Tanaka,Y., Kawamori,R. and Maeda,S.
  TITLE     Overexpression of Kruppel-like factor 7 regulates adipocytokine
            gene expressions in human adipocytes and inhibits glucose-induced
            insulin secretion in pancreatic beta-cell line
  JOURNAL   Mol Endocrinol 20 (4), 844-856 (2006)
   PUBMED   16339272
  REMARK    GeneRIF: KLF7 may contribute to the pathogenesis of type 2 diabetes
            through an impairment of insulin biosynthesis and secretion in
            pancreatic beta-cells and a reduction of insulin sensitivity in
            peripheral tissues.
REFERENCE   6  (bases 1 to 8365)
  AUTHORS   Butcher,L.M., Meaburn,E., Knight,J., Sham,P.C., Schalkwyk,L.C.,
            Craig,I.W. and Plomin,R.
  TITLE     SNPs, microarrays and pooled DNA: identification of four loci
            associated with mild mental impairment in a sample of 6000 children
  JOURNAL   Hum Mol Genet 14 (10), 1315-1325 (2005)
   PUBMED   15800012
REFERENCE   7  (bases 1 to 8365)
  AUTHORS   Chiambaretta,F., De Graeve,F., Turet,G., Marceau,G., Gain,P.,
            Dastugue,B., Rigal,D. and Sapin,V.
  TITLE     Cell and tissue specific expression of human Kruppel-like
            transcription factors in human ocular surface
  JOURNAL   Mol Vis 10, 901-909 (2004)
   PUBMED   15570219
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 8365)
  AUTHORS   Suzuki,S., Chuang,L.F., Doi,R.H. and Chuang,R.Y.
  TITLE     Identification of opioid-regulated genes in human lymphocytic cells
            by differential display: upregulation of Kruppel-like factor 7 by
            morphine
  JOURNAL   Exp Cell Res 291 (2), 340-351 (2003)
   PUBMED   14644156
  REMARK    GeneRIF: KLF7 was upregulated by morphine at both the
            transcriptional and the translational levels, promoting cell growth
            up to day 4
REFERENCE   9  (bases 1 to 8365)
  AUTHORS   Pescucci,C., Meloni,I., Bruttini,M., Ariani,F., Longo,I., Mari,F.,
            Canitano,R., Hayek,G., Zappella,M. and Renieri,A.
  TITLE     Chromosome 2 deletion encompassing the MAP2 gene in a patient with
            autism and Rett-like features
  JOURNAL   Clin Genet 64 (6), 497-501 (2003)
   PUBMED   14986829
REFERENCE   10 (bases 1 to 8365)
  AUTHORS   Matsumoto,N., Laub,F., Aldabe,R., Zhang,W., Ramirez,F., Yoshida,T.
            and Terada,M.
  TITLE     Cloning the cDNA for a new human zinc finger protein defines a
            group of closely related Kruppel-like transcription factors
  JOURNAL   J Biol Chem 273 (43), 28229-28237 (1998)
   PUBMED   9774444
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC007879.4 and AC008062.3.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 23, 2018 this sequence version replaced NM_003709.3.
            
            Summary: The protein encoded by this gene is a member of the
            Kruppel-like transcriptional regulator family. Members in this
            family regulate cell proliferation, differentiation and survival
            and contain three C2H2 zinc fingers at the C-terminus that mediate
            binding to GC-rich sites. This protein may contribute to the
            progression of type 2 diabetes by inhibiting insulin expression and
            secretion in pancreatic beta-cells and by deregulating
            adipocytokine secretion in adipocytes. A pseudogene of this gene is
            located on the long arm of chromosome 3. Alternative splicing
            results in multiple transcript variants. [provided by RefSeq, Aug
            2012].
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803611.202014.1,
                                           SRR1803616.115505.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2149178, SAMN03267754
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000309446.11/ ENSP00000309570.6
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-482               AC007879.4         35882-36363         c
            483-1113            AC008062.3         125239-125869       c
            1114-1237           AC008062.3         89923-90046         c
            1238-8365           AC008062.3         75602-82729         c
FEATURES             Location/Qualifiers
     source          1..8365
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q33.3"
     gene            1..8365
                     /gene="KLF7"
                     /gene_synonym="UKLF"
                     /note="KLF transcription factor 7"
                     /db_xref="GeneID:8609"
                     /db_xref="HGNC:HGNC:6350"
                     /db_xref="MIM:604865"
     exon            1..482
                     /gene="KLF7"
                     /gene_synonym="UKLF"
                     /inference="alignment:Splign:2.1.0"
     CDS             381..1289
                     /gene="KLF7"
                     /gene_synonym="UKLF"
                     /note="isoform 1 is encoded by transcript variant 1;
                     ubiquitous Kruppel-like transcription factor;
                     krueppel-like factor 7; Kruppel-like factor 7
                     (ubiquitous); ubiquitous Kruppel-like factor; Kruppel like
                     factor 7"
                     /codon_start=1
                     /product="Krueppel-like factor 7 isoform 1"
                     /protein_id="NP_003700.1"
                     /db_xref="CCDS:CCDS2373.1"
                     /db_xref="GeneID:8609"
                     /db_xref="HGNC:HGNC:6350"
                     /db_xref="MIM:604865"
                     /translation="MDVLASYSIFQELQLVHDTGYFSALPSLEETWQQTCLELERYLQ
                     TEPRRISETFGEDLDCFLHASPPPCIEESFRRLDPLLLPVEAAICEKSSAVDILLSRD
                     KLLSETCLSLQPASSSLDSYTAVNQAQLNAVTSLTPPSSPELSRHLVKTSQTLSAVDG
                     TVTLKLVAKKAALSSVKVGGVATAAAAVTAAGAVKSGQSDSDQGGLGAEACPENKKRV
                     HRCQFNGCRKVYTKSSHLKAHQRTHTGEKPYKCSWEGCEWRFARSDELTRHYRKHTGA
                     KPFKCNHCDRCFSRSDHLALHMKRHI"
     exon            483..1113
                     /gene="KLF7"
                     /gene_synonym="UKLF"
                     /inference="alignment:Splign:2.1.0"
     exon            1114..1237
                     /gene="KLF7"
                     /gene_synonym="UKLF"
                     /inference="alignment:Splign:2.1.0"
     exon            1238..8365
                     /gene="KLF7"
                     /gene_synonym="UKLF"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7384..7389
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KLF7"
                     /gene_synonym="UKLF"
                     /note="hexamer: AATAAA"
     polyA_site      7414
                     /gene="KLF7"
                     /gene_synonym="UKLF"
                     /note="major polyA site"
     regulatory      8345..8350
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KLF7"
                     /gene_synonym="UKLF"
                     /note="hexamer: AATAAA"
     polyA_site      8365
                     /gene="KLF7"
                     /gene_synonym="UKLF"
ORIGIN      
        1 aacagcgctg cagaaataga tggcagcttc gtgtcagtga gtttgcatcc cccttcctga
       61 tccacgagct ggagtgatta gagccctgga agggaattgt tactcccgtg gagaagtccc
      121 cttttcctgg cagtcgtctg cactgtacac gctggatgcc tctctccatc caccccactc
      181 actcgctcct ctctcacctc ctctctccct ctcctgcatt gatttttttt tttccttttt
      241 agttgactga aacaaaacaa aacaaaaggg ccactggatg tctgccttct tggggggtga
      301 gccagacaga ctgacaaaca aacagcccca actgtgttcg ggggagggtt tcgcctcccg
      361 ttttgcccgg cagcagcagc atggacgtgt tggctagtta tagtatattc caggagctac
      421 aacttgtcca cgacaccggc tacttctcag ctttaccatc cctggaggag acctggcagc
      481 agacatgcct tgaattggaa cgctacctac agacggagcc ccggaggatc tcagagacct
      541 ttggtgagga cttggactgt ttcctccacg cttcccctcc cccgtgcatt gaggaaagct
      601 tccgtcgctt agaccccctg ctgctccccg tggaagcggc catctgtgag aagagctcgg
      661 cagtggacat cttgctctct cgggacaagt tgctatctga gacctgcctc agcctccagc
      721 cggccagctc ttctctagac agctacacag ccgtcaacca ggcccagctc aacgcagtga
      781 cctcattaac gcccccatcg tcccctgagc tcagccgcca tctggtcaaa acctcacaaa
      841 ctctctctgc cgtggatggc acggtgacgt tgaaactggt ggccaagaag gctgctctca
      901 gctccgtaaa ggtgggaggg gtcgcaacag ctgcagcagc cgtgacggct gcgggggccg
      961 ttaagagtgg acagagcgac agtgaccaag gagggctggg ggctgaagca tgtcccgaaa
     1021 acaagaagag ggttcaccgc tgtcagttta acgggtgccg gaaagtttat acaaaaagct
     1081 cccacttaaa ggcccaccag aggactcaca caggtgagaa gccttataag tgctcatggg
     1141 agggatgtga gtggcgtttt gcacgaagcg atgagctcac gaggcactac aggaaacaca
     1201 caggtgcaaa gcccttcaaa tgcaaccact gcgacaggtg tttttccagg tctgaccatc
     1261 ttgccctcca catgaagaga catatctaaa aaaccgaaag gccagagttg ccatggcatc
     1321 ggctagtgtc taaaggaaac gccatgaggc agggggctgg acttcaggcg gggacccatt
     1381 gcctcgcaga agaaagttct cacttataaa cctctgtaca cacacacaca cacacacaca
     1441 tatacacaca ctcacagacc cacacacata cacactgtca tgcactcaac tatatttaaa
     1501 atatatacgt ctattcttta tgccttgccc tagccagatg gaagaagatg aagaaggaaa
     1561 ccaggtgaac tcagcaaggc agactggctg cttacttcag cactattgga attatttccc
     1621 gctgttgcca atggaaatca aagaaaatgg atgtgacgtc tgtgcaggtg gacggcagtc
     1681 cgaggggctt atttcacttg cttctcagtg caacttgata ggagaatcca gcatcttaaa
     1741 gttgcatatg tgtagcacta atgtttcttt ttaaatagtt gggggaaaat gacctagaaa
     1801 accaaattgc agtttggtag ccaaaattaa ctcttggttt atttgtcctt tgtgtgtgaa
     1861 aagtcctact attccgtgcg tcagacttcc tcacagaact gttgactggt tttggttctt
     1921 agtactattg agatctttcg cgtcgatccc aacggcctta gcggcggcag actggaataa
     1981 caccttacac ctttctggcc tgcatttctg tagacttcac tctcaaggga ggagttttct
     2041 tttcttacgt tttgactttt gcacaccata tgcactaggg attctggaaa cttctagcat
     2101 gactgcaaag tggccaagag aataaagtcc ttgatgataa atcacagtat atcccttgag
     2161 cctcacctta ttgccagtgc tagatttttt ctttttaatc tctccgtttt tgctaacgaa
     2221 aacttgaaaa gcttatttgg aagcttaaat gttttatctt ttctccatgg actaaacctc
     2281 tccaggactc tctcggcacc tggatgtcca gctctcgaag cagccagtca gatgggacat
     2341 cacagttctc tcatcctcct tgaggcatga tgacctcagc tcatagtgat caaccgttgt
     2401 gctgtgtgtc attgctaccc cataaccagt tacagcatag atgtcgctag tctcagaggg
     2461 cagctgcgta tttaatttaa ctctggttta tgacctgaca aaaagccaaa aatatcactc
     2521 tttccaggag tggggaaaac tgaggatgcc tcccaagtct agtggcttca caaaagatca
     2581 tcctgtcttc tctgtcatgc ccactgagct cctattcccc tacgtgttac aatacacaat
     2641 ttaaaacgcc attgtgggag tgaagggttg acatttaagg aaaaggttga ggtgtttctc
     2701 tcatgggctg tctaaaagga gagacacgtt tctttctttc cttttttttt tggctaggcc
     2761 caccatgact tgtgacctag aacccccagg attaacagag gcctcacatt tactctgcaa
     2821 gctgactcca aaggagtcta cagtccttac ttgtcatgcc acactcacac atccagtagt
     2881 ggtctctatc tacccgcatt cctagctagc tggcactggc ctcaactcca aagactgcct
     2941 ttaggaccat caaatggcct atgcaagcaa gcggggtggt tattaggaca gattgtatat
     3001 tttgtatatt ctgggaccat cccttcaaga cacgtctata aaacaaaaat ggcgcttggt
     3061 ccacacacgg ttgctgctcc ctcctaccag ctggctcccc tcctgtcctc ctttgactgt
     3121 ttgactcatt gactgttaaa atgccacccc atacatattt gggatgcaaa actgaagtca
     3181 aaaggaaata atataagaaa cacaaacaca tatatgacag caaccttcaa gatctgggtt
     3241 ttcagctttc tgcaaccttt gttttcactg aaatgttgaa actactcgtc tgagggcaaa
     3301 ggaacctcct cacaaatgct atagctgcca attggacact tggggcattt cgaggtctgg
     3361 ccctaagaat ttactttctc cttttccttt tttctattta gaccaaaaaa aacaaaaaca
     3421 aaaacaaaaa aaaaaacaaa ataatacaaa acgaaaaaaa aagaaagaac acccgttaac
     3481 acacacgcgc acacacacac aaaatctgtc catttgccgg aggcaattgt atgtatgtta
     3541 gttggagggt attaaaaatc agttttattc caaagattta aaactagaca tgacttaaaa
     3601 acaatttctg gagcactgct tgctgacaat ctcgtagttc tctgctgcat ttgagtgcat
     3661 tttgtggcca gtccatcagg gcgtaccatg ggattatatt tgaatgtgtg gtgcatcctt
     3721 cctggatgaa ggatgtgtga gggaccttga acctcagctg tattaaactg tagcgcctcc
     3781 agtcagtgca ctagatgaaa cttttagaca ccctgaattc tgttggttcc tttcttttcc
     3841 tttatgtagc agcctccagc atgaatgcac gcacacgcca gtgatggcat taagccatgg
     3901 ccaccacgat ttgcaaatgt tctctcccaa gctggagctg ctcttgcctc tcgaatgcta
     3961 ttattaaggg tttataatac ttaatttaat tttcgaactg accaatgcaa ggctctatta
     4021 aaaagaaagt ttaaaaaatg caaaagagta atcattgctt gtttgctccc tattttcatc
     4081 tgtggtctca tttgaatgtg gcagaacaaa ggccctttgg tcctcatcag tgtctgaaat
     4141 gttcagtaat ttctctctct tttgtatcag tgaggtcctt tgtaatctgc tcctgacctt
     4201 tcttggagca gggtgcattg aaactcaatg gtggtgcttg cttgcttcag agtcatttgt
     4261 tgactgtgag aattggccta agaatttggt gggtgctaag tggatggctt tgaaactgtt
     4321 cttctttagc cgagttgaca cctgtgaatg atgaccagtc ctgatcattt tggaaatgga
     4381 tttgtaataa aacgtccatc acctctgcag tggcagagat ggttactaag agccgctaga
     4441 gcgagcaggt tttccaagaa gtaacctgaa gacattttgc tcccaagagg actggttatt
     4501 taaaacagtg cattaatgga catttgaaac acattaaacc cctttctcat ttcagttgtt
     4561 acctcctaac cctccagggg atcccaaatt tgaaaggaaa aacccggcct ggtgtttctg
     4621 gtggtgtcct aacaagcacg cttttatcca gggttcagat ttgttcatgt agaaaaagag
     4681 tttctaagcc actgacaatt tttttttttt gtaatttcaa attatacttc tttctcctgc
     4741 cacatgactg taagtcatag acatggaaac ctgaaattat aatgctgctc ctagctactg
     4801 gcctcctgcc ccacccatgg ttaatggctc agctcaatgc ctggtggtaa tgagtattat
     4861 gtccagaaaa agagatgttc agattccatg acaaagctgc atttttgtaa aaatattgga
     4921 gaccccaaaa tgaacttcat gctgaccatt tcctcctctc tgtgtgcttt cccttgcaaa
     4981 gcccttcaaa tatcctcttc tctcgacgcc atctcctctc cacctgcacc tcttgtgccc
     5041 tttgtacatc tttgattgcc tgatgataac agggtaaaag gacagccaac ctcatgcctg
     5101 attagcagaa ctgaatccta gttttaaaaa atcttctctg gcttcagaga agattttata
     5161 aggacttttg tttgggataa gctttccaga ttatccatgt ctatttgcat caaaggggaa
     5221 agaaatgggg cttttggatg gctcttccag tgcattcgga acattgcctc ttgcctttat
     5281 tcctgcattt tatggcaaag ccaaaagaaa ctcaagttgc aagaacaaaa cccagtgact
     5341 cgttttgatg gttcaaaatg gtttccttta tggaagtcac ttcataaaat gttaagtaaa
     5401 aagtgggaag tgcttctgtc ttctcttttg catgagttgc ttttaggagc aggaagaagg
     5461 taggcaaagt aagataaaga tgcaacacat ttaactacaa aaatcaggtt cattttttag
     5521 tttattagaa tttttttgaa atcttaagag ggccagcatt tctggctaca attttgcacc
     5581 cagaacattg ccaaaatgaa cattcagtaa atagaacctg attgaaattt actcctggaa
     5641 gctttccttt gcattttcgg gaagtggcca cctgccaagc gcaagagttg gggggcagga
     5701 ggggaggact caaattcagg gtgtctggat taaatttcgg tgaacatggt gatatctcag
     5761 tttgaaaact agagggccta tcctgagtat acatcaatgt ctctttgatg gcctactttc
     5821 ctcagtgagg atctttggga atacttgaga tggaacaaca gaaatgtgtg aaaggaagca
     5881 gaaacttctt gtaaataacg tgacctccca cgacgaactg cctgaggctt cagggttttt
     5941 tcttgctttt aacactctta aatctcctct gttggttcct aatagatccc agaaaaggga
     6001 aaaataaagc tgcagttaac tttcttatgt gcatccttcc aatagagtac tgtatttttc
     6061 aggtgttttg catttaacat aaaagtcctc gggaaacagg tgtcaaaaac agagagagaa
     6121 atcctgggcc atcacttcac aaatatccca aacaagatat tcttttcaaa cagggctccc
     6181 tctcagtggt catgagggaa ggttgataat gttctttgtt ggggactgtt tatacaattt
     6241 tttttcaact gtgagctttg gaatcgtaac ttgctgtgag tccagcttct gtctactgcc
     6301 ataagatgga ccccacgtca gcataatgag ggtggtatat atgctcgcac ctagacatgc
     6361 gcatatgtac ctgtcgtacc ttcacggaag gaaaacaggc tactgacgtt tcggaggagt
     6421 agccaccagt gcctaatatc ttttgggggg gatggatgct tataattgcc agtatatcga
     6481 aaccacactg ggagttccac atagcgggga ggggttgggg gtgggcagag gggacatttt
     6541 aaacctaggc ctttggactg gaggcagaac gatttctgca aacctaggtc ctgaaggctt
     6601 tggggcttat tggctggttc tcaacctttt tgttttttct tcccagcatg catttcctat
     6661 ctaaacccag acttagttta atttccttat ctttcacttc tgcttcattc cagggaggaa
     6721 aaatacacct gttaatggcc aagatctcct tgctaacaca gaggcaaaaa taaatgtcta
     6781 atgtttttga agcctcccct tcctttccac aagcccccac ccgcccccgc gtcaagctcc
     6841 ttctcccact tcctactccc acacaacttc ccagccactg aaacttttct ttcaaatctc
     6901 tattatcctc ttaacagttg cttgaataaa tttatttttg cactatacat tttctttttg
     6961 ccagatgtgt ctaacaagtg tgtttggaga gacctactcc cagccccgtc tccttccccg
     7021 cctccccccg tcacattctc tcaggccttc tctggtattt ataatatatc acagaagtac
     7081 ccagtcttat agccctcggt tatgcctttt tttgacattt tatttttttt aagcttttta
     7141 tatatatata tatataaata tattactttg tcaagttttt ttgctgtaca aaagtcttaa
     7201 gatttaaaac tattatttgt attatatgat ggtggtatgt taatgttaca aaattattaa
     7261 tgaagaaaaa atttattttt gttactggtc tgtttcataa ttctttttta aattggtata
     7321 ttgtaagata tctatgcaaa aaatgttatg tgacgcattt ttatttaaga atgtaatatg
     7381 tgtaataaac agtagaatgt gtttggcctt ggaatacttt actgtatttc tccttagctt
     7441 gtttcactgg ggaaaaaaat cttcgaaaga cgcaagtggg tacttacata cttcgtgaaa
     7501 gttttctttc ttggagaaag ggaaagcaaa aggttgtatt aggttatctt cgtttgggaa
     7561 gttgtgtgtg tgtgtgcgta tgtgtgtatt ttatagtttc attgaggcag ctcaatgccc
     7621 aaataagggt cactgagttt atttcttcaa ggggaaaaag ggagccaatt gttggagatt
     7681 atgaaaagca atattttaga atgatagaga ttacaagatg ttatttgttt agggggttgg
     7741 gagaggctta ttgaaagcgg tttatttggc gagagaagga ggcagtttgt tctgggatgg
     7801 tgtttaatag gaacctattg ggaaaggatc tttgaagcag tctgtgaagg aggaagggta
     7861 aagatcagag ggaataattt aggtgagggg tagggggcag taaaatgaca ggaggtggtt
     7921 ggagtgggga ggaaatgggt aaccggaagc caggaaatcc agctggctgt ggagagtaca
     7981 aaaaactaga tggaaataca agcagcttca gacccagaga agagagggag atgaaagccc
     8041 cagggaaaat tctcagaact gaaaagaaaa gtactaaaat ctctgccaca cacgacttcc
     8101 aggaaagagc atcaccagta aggaggaagg tagagaaccc agctggtggt gtcgcctcag
     8161 catcccgagc tcagcgattc cccgagagaa gtggtgtcat tcacaggaaa cagcagtaaa
     8221 acacatttgt cacatgggac acagcagtag tcaagctttc tttgcattct ttggacttac
     8281 agaagtggat acggtggtga ataacctcta tccctaatca aatgaatctg acaagaaact
     8341 ttccaataaa tgtttacttt agaaa
//
