LOCUS       NM_017576               7257 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens kinesin family member 27 (KIF27), transcript variant
            1, mRNA.
ACCESSION   NM_017576 XM_937987 XM_943500 XM_943505 XM_943510
VERSION     NM_017576.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7257)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 7257)
  AUTHORS   Nozawa,Y.I., Yao,E., Gacayan,R., Xu,S.M. and Chuang,P.T.
  TITLE     Mammalian Fused is essential for sperm head shaping and
            periaxonemal structure formation during spermatogenesis
  JOURNAL   Dev Biol 388 (2), 170-180 (2014)
   PUBMED   24525297
REFERENCE   3  (bases 1 to 7257)
  AUTHORS   Klejnot,M. and Kozielski,F.
  TITLE     Structural insights into human Kif7, a kinesin involved in Hedgehog
            signalling
  JOURNAL   Acta Crystallogr D Biol Crystallogr 68 (Pt 2), 154-159 (2012)
   PUBMED   22281744
REFERENCE   4  (bases 1 to 7257)
  AUTHORS   Daire,V. and Pous,C.
  TITLE     Kinesins and protein kinases: key players in the regulation of
            microtubule dynamics and organization
  JOURNAL   Arch Biochem Biophys 510 (2), 83-92 (2011)
   PUBMED   21345331
  REMARK    Review article
REFERENCE   5  (bases 1 to 7257)
  AUTHORS   Sweetser,D.A., Peniket,A.J., Haaland,C., Blomberg,A.A., Zhang,Y.,
            Zaidi,S.T., Dayyani,F., Zhao,Z., Heerema,N.A., Boultwood,J.,
            Dewald,G.W., Paietta,E., Slovak,M.L., Willman,C.L., Wainscoat,J.S.,
            Bernstein,I.D. and Daly,S.B.
  TITLE     Delineation of the minimal commonly deleted segment and
            identification of candidate tumor-suppressor genes in del(9q) acute
            myeloid leukemia
  JOURNAL   Genes Chromosomes Cancer 44 (3), 279-291 (2005)
   PUBMED   16015647
REFERENCE   6  (bases 1 to 7257)
  AUTHORS   Katoh,Y. and Katoh,M.
  TITLE     Characterization of KIF7 gene in silico
  JOURNAL   Int J Oncol 25 (6), 1881-1886 (2004)
   PUBMED   15547730
REFERENCE   7  (bases 1 to 7257)
  AUTHORS   Katoh,Y. and Katoh,M.
  TITLE     KIF27 is one of orthologs for Drosophila Costal-2
  JOURNAL   Int J Oncol 25 (6), 1875-1880 (2004)
   PUBMED   15547729
REFERENCE   8  (bases 1 to 7257)
  AUTHORS   Oduru,S., Campbell,J.L., Karri,S., Hendry,W.J., Khan,S.A. and
            Williams,S.C.
  TITLE     Gene discovery in the hamster: a comparative genomics approach for
            gene annotation by sequencing of hamster testis cDNAs
  JOURNAL   BMC Genomics 4 (1), 22 (2003)
   PUBMED   12783626
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DC376766.1, AY237536.1 and
            AL354733.15.
            
            On Nov 22, 2018 this sequence version replaced NM_017576.3.
            
            Summary: This gene is a member of the KIF27 (kinesin 4) sub-family
            of the mammalian kinesin family. The gene is an ortholog of the
            Drosophila Cos2 gene, which plays an important role in the Hedgehog
            signaling pathway. The encoded protein contains an N-terminal motor
            domain which includes nucleotide-binding and
            microtubule-interacting regions, a stalk domain containing a
            predicted coiled coil motif and a C-terminal tail domain.
            Alternatively spliced transcript variants have been observed for
            this gene. Pseudogenes associated with this gene are located on
            chromosome 9. [provided by RefSeq, Dec 2012].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY237536.1, BC140788.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000297814.7/ ENSP00000297814.2
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-5                 DC376766.1         34-38
            6-4658              AY237536.1         1-4653
            4659-7257           AL354733.15        34991-37589         c
FEATURES             Location/Qualifiers
     source          1..7257
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q21.32"
     gene            1..7257
                     /gene="KIF27"
                     /note="kinesin family member 27"
                     /db_xref="GeneID:55582"
                     /db_xref="HGNC:HGNC:18632"
                     /db_xref="MIM:611253"
     exon            1..62
                     /gene="KIF27"
                     /inference="alignment:Splign:2.1.0"
     exon            63..447
                     /gene="KIF27"
                     /inference="alignment:Splign:2.1.0"
     CDS             150..4355
                     /gene="KIF27"
                     /note="isoform A is encoded by transcript variant 1;
                     kinesin-like protein KIF27"
                     /codon_start=1
                     /product="kinesin-like protein KIF27 isoform A"
                     /protein_id="NP_060046.1"
                     /db_xref="CCDS:CCDS6665.1"
                     /db_xref="GeneID:55582"
                     /db_xref="HGNC:HGNC:18632"
                     /db_xref="MIM:611253"
                     /translation="MEEIPVKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDRV
                     FTFDFVFGKNSTQDEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASV
                     VEGQKGIIPRAIQEIFQSISEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIRE
                     DEKGNTVIVGAKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQV
                     HKNMEAAEDGSWYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGN
                     VISALGDPRRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKY
                     ANRARNIRNKPTVNFSPESDRIDEMEFEIKLLREALQSQQAGVSQTTQINREGSPDTN
                     RIHSLEEQVAQLQGECLGYQCCVEEAFTFLVDLKDTVRLNEKQQHKLQEWFNMIQEVR
                     KAVLTSFRGIGGTASLEEGPQHVTVLQLKRELKKCQCVLAADEVVFNQKELEVKELKN
                     QVQMMVQENKGHAVSLKEAQKVNRLQNEKIIEQQLLVDQLSEELTKLNLSVTSSAKEN
                     CGDGPDARIPERRPYTVPFDTHLGHYIYIPSRQDSRKVHTSPPMYSLDRIFAGFRTRS
                     QMLLGHIEEQDKVLHCQFSDNSDDEESEGQEKSGTRCRSRSWIQKPDSVCSLVELSDT
                     QDETQKSDLENEDLKIDCLQESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLI
                     KELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVK
                     LQKEFRKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHMKYQKIQLQ
                     RKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKGSFGS
                     IDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSHLENK
                     KLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQL
                     QKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEAAIEYRNESIQNRQKSLRASFH
                     NLSRGEANVLEKLACLSPVEIRTILFRYFNKVVNLREAERKQQLYNEEMKMKVLERDN
                     MVRELESALDHLKLQCDRRLTLQQKEHEQKMQLLLHHFKEQDGEGIMETFKTYEDKIQ
                     QLEKDLYFYKKTSRDHKKKLKELVGEAIRRQLAPSEYQEAGDGVLKPEGGGMLSEELK
                     WASRPESMKLSGREREMDSSASSLRTQPNPQKLWEDIPELPPIHSSLAPPSGHMLGNE
                     NKTETDDNQFTKSHSRLSSQIQVVGNVGRLHGVTPVKLCRKELRQISALELSLRRSSL
                     GVGIGSMAADSIEVSRKPRDLKT"
     exon            448..648
                     /gene="KIF27"
                     /inference="alignment:Splign:2.1.0"
     exon            649..1607
                     /gene="KIF27"
                     /inference="alignment:Splign:2.1.0"
     exon            1608..1751
                     /gene="KIF27"
                     /inference="alignment:Splign:2.1.0"
     exon            1752..1958
                     /gene="KIF27"
                     /inference="alignment:Splign:2.1.0"
     exon            1959..2128
                     /gene="KIF27"
                     /inference="alignment:Splign:2.1.0"
     exon            2129..2232
                     /gene="KIF27"
                     /inference="alignment:Splign:2.1.0"
     exon            2233..2388
                     /gene="KIF27"
                     /inference="alignment:Splign:2.1.0"
     exon            2389..2594
                     /gene="KIF27"
                     /inference="alignment:Splign:2.1.0"
     exon            2595..2792
                     /gene="KIF27"
                     /inference="alignment:Splign:2.1.0"
     exon            2793..2906
                     /gene="KIF27"
                     /inference="alignment:Splign:2.1.0"
     exon            2907..3083
                     /gene="KIF27"
                     /inference="alignment:Splign:2.1.0"
     exon            3084..3299
                     /gene="KIF27"
                     /inference="alignment:Splign:2.1.0"
     exon            3300..3506
                     /gene="KIF27"
                     /inference="alignment:Splign:2.1.0"
     exon            3507..3705
                     /gene="KIF27"
                     /inference="alignment:Splign:2.1.0"
     exon            3706..3870
                     /gene="KIF27"
                     /inference="alignment:Splign:2.1.0"
     exon            3871..7257
                     /gene="KIF27"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7235..7240
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KIF27"
                     /note="hexamer: AATAAA"
     polyA_site      7257
                     /gene="KIF27"
                     /note="major polyA site"
ORIGIN      
        1 gtggcagagc gaagctgagg agtccagcgc tcgccgacag gggcctgggc tgtcccgagc
       61 cggaatccag atcttacata agatggaagt ctctcacact agatactgaa cattaaatag
      121 aaaatctatt tagtaaaatc taagttgcca tggaagaaat accagtaaaa gttgctgtaa
      181 gaattagacc tctgctttgc aaagaagctc ttcataatca tcaagtttgt gtgagagtta
      241 ttccaaacag ccagcaagtt atcattggga gagatagagt cttcactttt gattttgttt
      301 ttggcaaaaa ttccactcaa gatgaagttt ataacacatg tataaagccc ctagtgttgt
      361 cactcattga gggctataat gcaactgttt ttgcctatgg acaaactgga tctgggaaga
      421 catacaccat tggagggggc catattgctt cagttgtgga gggccaaaag ggtatcattc
      481 ctcgagctat tcaagaaata tttcaaagca tctctgaaca tcctagcatt gactttaatg
      541 taaaagtatc ttatatagaa gtgtacaagg aagacctaag agatcttcta gaattggaga
      601 catccatgaa ggatcttcac atccgagaag atgaaaaagg aaacacagtg attgttgggg
      661 ccaaggaatg ccatgtggag agtgcaggtg aagtgatgag tcttttggag atggggaatg
      721 cagccagaca tacaggtacc actcaaatga atgagcactc cagcagatca catgcaattt
      781 ttacaatcag catttgtcaa gttcataaaa atatggaggc agctgaagat ggatcatggt
      841 attcccctcg gcatattgtc tcaaagttcc actttgtgga tttggcagga tcagaaagag
      901 taaccaaaac ggggaatact ggtgaacggt tcaaagaatc cattcaaatc aatagtggat
      961 tgctggcttt aggaaatgta ataagcgctc ttggggaccc acgcaggaag agttcacata
     1021 ttccatatag ggatgctaaa attacccggc ttctgaaaga ttctctggga ggcagtgcta
     1081 agactgtcat gatcacatgt gtcagcccct cctcctcgaa ttttgatgag tccttaaatt
     1141 ctctcaaata tgccaacaga gcacggaaca ttagaaacaa acccactgta aacttcagcc
     1201 ccgagtcaga ccgtatagat gaaatggaat ttgagattaa attgcttcga gaagctttgc
     1261 aaagccagca ggctggtgtc agccaaacta cccagatcaa tcgagaaggg agtcctgata
     1321 caaataggat tcattctctt gaggagcaag tagctcagct tcaaggagaa tgtctgggtt
     1381 accagtgttg tgtagaagaa gcctttacct tcctggttga cctaaaagat actgtcagac
     1441 taaacgaaaa gcagcaacac aaactgcagg agtggtttaa catgatccaa gaggtcagga
     1501 aggctgtcct cacctcattt cgaggaatcg gaggcactgc aagtctggaa gaaggaccac
     1561 agcatgttac agttctccag ctgaagagag agcttaagaa atgccagtgt gtgcttgctg
     1621 ctgatgaagt agtatttaat cagaaggaac tggaggtgaa ggaactgaag aatcaagtgc
     1681 agatgatggt acaggaaaac aaagggcatg ctgtatcttt gaaagaagcg caaaaagtga
     1741 atagactgca gaatgaaaaa ataatagaac aacaacttct tgtggatcaa ctgagtgaag
     1801 aactaacaaa acttaacctg tcagtgactt cttcagctaa agaaaattgt ggagatgggc
     1861 cagatgccag gatccctgaa aggagaccat atactgtacc atttgatact catttggggc
     1921 attatattta tatcccatca agacaagatt ccaggaaggt ccacacaagt ccgcctatgt
     1981 actctctgga tcgaatattt gctggatttc gaacacgaag tcagatgctg ttgggtcaca
     2041 tagaagaaca agataaggtc ctccactgcc aattttctga taacagtgat gatgaagaat
     2101 cagaaggcca agagaaatct ggaactagat gtagaagtcg ttcatggatt cagaagccag
     2161 actctgtttg ttcccttgtt gaattgagtg atactcagga tgaaacacaa aagtcagatt
     2221 tggagaatga agatttaaag attgattgtc tccaggagag tcaagaattg aatttgcaaa
     2281 aattaaagaa ttcagaacgc atacttactg aagctaaaca aaaaatgaga gaacttacaa
     2341 ttaacatcaa gatgaaggaa gatctgatta aagaattaat aaaaacaggt aatgatgcca
     2401 agtctgtaag caagcagtat tctttgaaag taacaaagct agagcatgat gcagaacagg
     2461 caaaagtcga actgattgaa acacaaaagc agctacagga gctggaaaac aaagatcttt
     2521 ctgatgttgc aatgaaggta aaattacaga aagagtttcg taaaaagatg gatgctgcaa
     2581 agctgagagt tcaggtcttg cagaagaagc aacaagatag taagaaactg gcatcactgt
     2641 caatccaaaa tgagaaacgt gctaatgagc tagagcagag tgtagatcac atgaaatatc
     2701 aaaagataca gctacaaaga aaactacgag aagaaaatga aaaaaggaag caactggatg
     2761 cagtaattaa gcgggaccag caaaaaatca aagaaataca attaaaaaca ggacaggaag
     2821 aaggtctaaa accgaaagct gaggaccttg atgcatgtaa cttgaaaagg agaaaaggtt
     2881 cgtttggaag tatagaccat ctccagaaat tggatgagca aaagaaatgg ttagatgaag
     2941 aagtagagaa agttctgaac caacgccaag aattagagga gctggaagca gacttaaaga
     3001 aacgggaggc catagtttct aagaaggagg ctctgttaca ggagaagagt cacctggaaa
     3061 ataagaaatt gagatctagt caggccttaa acacagatag tttgaaaata tcaactcgcc
     3121 tgaacttact ggaacaagag ttgtctgaaa agaatgtgca gctccagacc agtacagctg
     3181 aggagaaaac aaagatttca gaacaagttg aagtcctcca gaaagaaaag gatcagctcc
     3241 agaaacgcag acacaatgtg gatgaaaaac ttaaaaatgg tagagtgtta tcacctgaag
     3301 aagaacatgt tcttttccaa cttgaagaag ggattgaagc tttggaagct gcaattgaat
     3361 acaggaatga aagtatccag aatcgccaga agtcacttag agcatcattc cataacctct
     3421 ctcgtggtga agcaaatgtc ttggaaaagc tagcttgcct gagtcctgtt gagattagaa
     3481 ctattctttt cagatatttc aataaggtgg tgaatttgcg agaagctgaa cggaaacaac
     3541 agttatataa tgaagaaatg aaaatgaaag ttctggaacg ggataatatg gttcgtgaat
     3601 tagaatctgc actggaccat ctaaaattgc agtgtgaccg gagactgacc ctccagcaaa
     3661 aggaacacga acaaaagatg cagttgctat tacatcattt caaagaacaa gatggagaag
     3721 gcattatgga aactttcaaa acatatgaag ataaaatcca gcagttggaa aaagatcttt
     3781 atttctataa gaaaaccagc cgggatcata agaagaaact taaggaactg gtaggggaag
     3841 caattcggcg gcaactagca ccatcagagt atcaagaggc tggagatgga gtcctgaagc
     3901 cagaaggagg aggcatgctt tcagaagaat taaaatgggc atccagacct gaaagtatga
     3961 aattaagtgg aagagaaaga gaaatggaca gttcagcaag cagcttaaga acacagccaa
     4021 atcctcaaaa gctctgggaa gatatcccag aattacctcc aattcatagt tctttagcac
     4081 cccccagtgg gcatatgtta ggtaatgaga ataaaacaga aacagatgat aatcagttta
     4141 caaaatctca cagtcgactg tcatcccaaa ttcaggttgt gggaaatgtg ggacgacttc
     4201 atggtgtcac acctgtaaaa ctgtgtcgaa aagaattacg tcaaatttcc gccttggaac
     4261 tatcattgcg acgttccagt cttggagttg gcattggatc aatggctgct gattccatcg
     4321 aagtatctag gaaaccaagg gacttaaaaa cttagacatt gaataataga acttttagta
     4381 gatatgtaaa aagattcctt tttctaacct gttaaaaact aaagctcaag ttcactacct
     4441 ctttcctcag aataaaggaa gaaggggagg aaggaatccc taattctttt atatgctata
     4501 gatgtgtaca tcttctatat atatttgggg agttttagtt tatattccca tagtaatcaa
     4561 acatgttttc caatacttga taacatttaa atatttataa atacgcttaa atgtttttcc
     4621 aggcatattt gaagattaaa actagtaata gactaaaata tctatcaagt atgtattatt
     4681 atataatata aatgtacatc ataaaagtat gttacaatat aactatatta ttgttattct
     4741 caaatacaag tatatttttt ttttaaaaga tccagctaaa tcttgctttt gtcagaggga
     4801 gtcacctgct gcatatgtgg gctaagacaa cctctcagct ttatggattg aggctcattt
     4861 acagtcctca gaactcacag aaacggtcag tcctgacttt ttaaacatgc tcactgttct
     4921 gtttctggaa tttttttgga tttttaaaaa tttataatgc tatcttttat gtttgctaat
     4981 attatgcaat ataagttttc atgtctttcc tgctctatac actcaatata tctctcatta
     5041 tgttactaaa actgggagaa atgaatgctg ttccatggaa cacggaaatt atagaataaa
     5101 actaaagcat tctaacattt caagagaaag aacactggtt atgacatctc tggtcacatg
     5161 gagtatgtct gtaaagcttg aagtcttgcc aaagcatctt taatgatttg atgggcttaa
     5221 gtctgatatt tttttctata acctccttag tcaggctttg cacaccggcc aaactacact
     5281 ggggctgtaa atatgtcaat gaaattttta ctaaaatctc caagtttttc tggtcaaaat
     5341 tttactatat aatgtacaat ttagtttgga attaagaact aaacagtttg cacaccaaat
     5401 gtagtttgta ctttttaacc atatttttca gttataggaa acatccattg taatgacctg
     5461 aggaattatt ttgttactta tgttgttctt tgttactttt ccaaaacact tgtaaaccga
     5521 agttgagttt cttaaactaa ttaatgtttt gttgggggct gtagcaaaac catcctgaca
     5581 tggatgctta ctcagagtca cccacttcct tgctgaatcc atttttttct gatgtagtgc
     5641 tgctacagac cttttccttt tgtcctttcc tctgttgctg tggatttgat catctcacat
     5701 aggacccaaa ctgtcaccct gtgctcaaag acttaaggct tcctttctct cattgctagc
     5761 ccctagggag tagagtttct tggtctcctt gctaaaaacc agttccttta ggaaacaaac
     5821 caaaacaaaa caaacttata aaaaggaaaa tatctcttaa gcatggtact aaaatttatt
     5881 taaattaaat agatttctgt ggacttacct gggaatgaaa caatttataa atattggtcc
     5941 aatgagatac tattttctaa atttcaaaaa actaatttac aaacttaact gggaaatttt
     6001 atttttacca ggaactgttt gaagtcagat tctggtttcc agctagtctt ccatttttat
     6061 aaatttatgt acatttatat ataaatataa atcatacaaa ccaaaggtaa aacatacaca
     6121 ttataaatat gtataaatgc actgaccttt tgccattatt atatatattt catatatata
     6181 tatgtatata cacttgtaca tatacaagta tataaggaaa tgtgtttgta tttccataag
     6241 taaaacaagt atgtgtaaat taattatttc taactaaggc atagcacata atcttacaag
     6301 gaacttataa ttaggatctt tgttaataaa tacatattta tttaaatata ttattgctgt
     6361 gctttgttga aggcactgac cttttaccat tatatatact tgtatataaa cacttgtata
     6421 tatatagtat tatatatata cttgtatata gatataggtt atacatttta cattatttca
     6481 ctttatatta tttcatatca tattttatat catgatatat cattatatag ctataatgta
     6541 tatatagata cacttgtata tatacataga tatagatata tataatggcc aaaggtcagt
     6601 gcccttagca agcacagcaa tatttataaa taaatattta ttaatgaaga tcctaataat
     6661 aagttcctta taagattaag taatgtgcta tgcgttattt aggaataatt catttaagaa
     6721 tgtattctga tactggaatc ctacttgctc aagaaattaa cacatacttg ttttacctgt
     6781 ggaaatacac atttcctcaa agccaactca ctaataaagc aagaaaattt atatcaaaac
     6841 aacaatgatt aggtttgact atgcaattgt gagttgattt ctaaataaca aaggtatggt
     6901 gtttttcttc cttttggtta aacatatatc ctttatatat atgacatttc atgccacata
     6961 tgcaaacaca catataaata acgtcgtgaa taatatattc tggaaatgaa cctctggtca
     7021 ttctagttta gtcggtgttc tcacaaagga aagaaaaaaa ttagacacct acccaaggca
     7081 agtaaaatta tttttttaca tatactaata atgattttac tttttcacat gctttttcta
     7141 aacattttgt cactttattg cctttttgca tgtatataaa atgtttgtgg ttttcttttt
     7201 ttcgttcatt atgttctttt ttcctcttaa ctgtaataaa gcatttgaaa ggaaaaa
//
