LOCUS       NM_001365951           10855 bp    mRNA    linear   PRI 10-FEB-2025
DEFINITION  Homo sapiens kinesin family member 1B (KIF1B), transcript variant
            3, mRNA.
ACCESSION   NM_001365951
VERSION     NM_001365951.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 10855)
  AUTHORS   Segal,D., Maier,S., Mastromarco,G.J., Qian,W.W., Nabeel-Shah,S.,
            Lee,H., Moore,G., Lacoste,J., Larsen,B., Lin,Z.Y.,
            Selvabaskaran,A., Liu,K., Smibert,C., Zhang,Z., Greenblatt,J.,
            Peng,J., Lee,H.O., Gingras,A.C. and Taipale,M.
  TITLE     A central chaperone-like role for 14-3-3 proteins in human cells
  JOURNAL   Mol Cell 83 (6), 974-993 (2023)
   PUBMED   36931259
REFERENCE   2  (bases 1 to 10855)
  AUTHORS   Cho,N.H., Cheveralls,K.C., Brunner,A.D., Kim,K., Michaelis,A.C.,
            Raghavan,P., Kobayashi,H., Savy,L., Li,J.Y., Canaj,H., Kim,J.Y.S.,
            Stewart,E.M., Gnann,C., McCarthy,F., Cabrera,J.P., Brunetti,R.M.,
            Chhun,B.B., Dingle,G., Hein,M.Y., Huang,B., Mehta,S.B.,
            Weissman,J.S., Gomez-Sjoberg,R., Itzhak,D.N., Royer,L.A., Mann,M.
            and Leonetti,M.D.
  TITLE     OpenCell: Endogenous tagging for the cartography of human cellular
            organization
  JOURNAL   Science 375 (6585), eabi6983 (2022)
   PUBMED   35271311
REFERENCE   3  (bases 1 to 10855)
  AUTHORS   Chen,W., Song,J., Liu,S., Tang,B., Shen,L., Zhu,J., Fang,S., Wu,F.,
            Zheng,L., Qiu,R., Chen,C., Gao,Y., Tu,J., Zhao,Z. and Ji,J.
  TITLE     USP9X promotes apoptosis in cholangiocarcinoma by modulation
            expression of KIF1Bbeta via deubiquitinating EGLN3
  JOURNAL   J Biomed Sci 28 (1), 44 (2021)
   PUBMED   34112167
  REMARK    GeneRIF: USP9X promotes apoptosis in cholangiocarcinoma by
            modulation expression of KIF1Bbeta via deubiquitinating EGLN3.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 10855)
  AUTHORS   Seo,S.H., Kim,J.H., Kim,M.J., Cho,S.I., Kim,S.J., Kang,H.,
            Shin,C.S., Park,S.S., Lee,K.E. and Seong,M.W.
  TITLE     Whole Exome Sequencing Identifies Novel Genetic Alterations in
            Patients with Pheochromocytoma/Paraganglioma
  JOURNAL   Endocrinol Metab (Seoul) 35 (4), 909-917 (2020)
   PUBMED   33397043
  REMARK    GeneRIF: Whole Exome Sequencing Identifies Novel Genetic
            Alterations in Patients with Pheochromocytoma/Paraganglioma.
REFERENCE   5  (bases 1 to 10855)
  AUTHORS   Saito,M., Hayashi,Y., Suzuki,T., Tanaka,H., Hozumi,I. and Tsuji,S.
  TITLE     Linkage mapping of the gene for Charcot-Marie-Tooth disease type 2
            to chromosome 1p (CMT2A) and the clinical features of CMT2A
  JOURNAL   Neurology 49 (6), 1630-1635 (1997)
   PUBMED   9409358
REFERENCE   6  (bases 1 to 10855)
  AUTHORS   Gong,T.L., Burmeister,M. and Lomax,M.I.
  TITLE     The novel gene D4Mil1e maps to mouse chromosome 4 and human
            chromosome 1p36
  JOURNAL   Mamm Genome 7 (10), 790-791 (1996)
   PUBMED   8854876
REFERENCE   7  (bases 1 to 10855)
  AUTHORS   Nangaku,M., Sato-Yoshitake,R., Okada,Y., Noda,Y., Takemura,R.,
            Yamazaki,H. and Hirokawa,N.
  TITLE     KIF1B, a novel microtubule plus end-directed monomeric motor
            protein for transport of mitochondria
  JOURNAL   Cell 79 (7), 1209-1220 (1994)
   PUBMED   7528108
REFERENCE   8  (bases 1 to 10855)
  AUTHORS   Zuchner,S.
  TITLE     MFN2 Hereditary Motor and Sensory Neuropathy
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301684
REFERENCE   9  (bases 1 to 10855)
  AUTHORS   Bird,T.D.
  TITLE     Charcot-Marie-Tooth Hereditary Neuropathy Overview
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301532
REFERENCE   10 (bases 1 to 10855)
  AUTHORS   Bird,T.D.
  TITLE     Charcot-Marie-Tooth Neuropathy Type 2 - RETIRED CHAPTER, FOR
            HISTORICAL REFERENCE ONLY
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301462
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL358013.19 and AL139424.21.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Oct 30, 2019 this sequence version replaced NM_001365951.2.
            
            Transcript Variant: This variant (3) represents the longest
            transcript and encodes the longest isoform (c). Variants 3 and 4
            both encode the same isoform (c).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803614.65429.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA2145743
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000676179.1/ ENSP00000502065.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-309               AL358013.19        25212-25520
            310-494             AL358013.19        46892-47076
            495-571             AL358013.19        70889-70965
            572-751             AL358013.19        73135-73314
            752-817             AL358013.19        76547-76612
            818-996             AL358013.19        82022-82200
            997-1108            AL358013.19        82794-82905
            1109-1186           AL358013.19        86144-86221
            1187-1252           AL358013.19        86883-86948
            1253-1270           AL358013.19        87656-87673
            1271-1346           AL358013.19        90070-90145
            1347-1425           AL358013.19        90963-91041
            1426-1568           AL358013.19        92628-92770
            1569-1610           AL358013.19        93739-93780
            1611-1822           AL358013.19        96964-97175
            1823-1902           AL358013.19        105724-105803
            1903-1978           AL358013.19        106689-106764
            1979-2058           AL358013.19        109728-109807
            2059-2165           AL358013.19        110302-110408
            2166-2249           AL358013.19        111224-111307
            2250-2430           AL358013.19        111539-111719
            2431-2503           AL358013.19        111816-111888
            2504-2597           AL358013.19        134685-134778
            2598-2746           AL358013.19        136351-136499
            2747-2925           AL358013.19        138526-138704
            2926-3063           AL358013.19        139400-139537
            3064-3312           AL358013.19        140753-141001
            3313-3431           AL358013.19        149162-149280
            3432-3517           AL358013.19        151299-151384
            3518-3647           AL358013.19        151716-151845
            3648-3810           AL358013.19        152013-152175
            3811-3901           AL358013.19        154411-154501
            3902-4020           AL358013.19        156692-156810
            4021-4076           AL358013.19        157874-157929
            4077-4185           AL358013.19        160487-160595
            4186-4252           AL358013.19        162403-162469
            4253-4337           AL358013.19        163291-163375
            4338-4443           AL358013.19        167273-167378
            4444-4558           AL139424.21        5959-6073
            4559-4692           AL139424.21        6722-6855
            4693-4754           AL139424.21        8313-8374
            4755-4900           AL139424.21        10130-10275
            4901-5140           AL139424.21        10439-10678
            5141-5212           AL139424.21        13497-13568
            5213-5334           AL139424.21        16171-16292
            5335-5484           AL139424.21        19346-19495
            5485-5677           AL139424.21        19884-20076
            5678-5796           AL139424.21        20285-20403
            5797-10855          AL139424.21        21575-26633
FEATURES             Location/Qualifiers
     source          1..10855
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.22"
     gene            1..10855
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /note="kinesin family member 1B"
                     /db_xref="GeneID:23095"
                     /db_xref="HGNC:HGNC:16636"
                     /db_xref="MIM:605995"
     exon            1..309
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            310..494
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     CDS             389..5839
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /EC_number="5.6.1.3"
                     /note="isoform c is encoded by transcript variant 3;
                     kinesin superfamily protein KIF1B; kinesin-like protein
                     KIF1B; Charcot-Marie-Tooth neuropathy type II"
                     /codon_start=1
                     /product="kinesin-like protein KIF1B isoform c"
                     /protein_id="NP_001352880.1"
                     /db_xref="CCDS:CCDS90858.1"
                     /db_xref="GeneID:23095"
                     /db_xref="HGNC:HGNC:16636"
                     /db_xref="MIM:605995"
                     /translation="MSGASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPK
                     EAPKSFSFDYSYWSHTSPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAG
                     KSYTMMGKQEESQAGIIPQLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNP
                     KNKGNLRVREHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSH
                     AVFTIVFTQKKHDNETNLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLT
                     TLGKVISALAEVDNCTSKSKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPA
                     DINYDETLSTLRYADRAKQIKCNAVINEDPNAKLVRELKEEVTRLKDLLRAQGLGDII
                     DIDPLIDDYSGSGSKYLKDFQNNKHRYLLASENQRPGHFSTASMGSLTSSPSSCSLSS
                     QVGLTSVTSIQERIMSTPGGEEAIERLKESEKIIAELNETWEEKLRKTEAIRMEREAL
                     LAEMGVAIREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGQADAERR
                     QDIVLSGAHIKEEHCIFRSERSNSGEVIVTLEPCERSETYVNGKRVSQPVQLRSGNRI
                     IMGKNHVFRFNHPEQARAEREKTPSAETPSEPVDWTFAQRELLEKQGIDMKQEMEKRL
                     QEMEILYKKEKEEADLLLEQQRLDYESKLQALQKQVETRSLAAETTEEEEEEEEVPWT
                     QHEFELAQWAFRKWKSHQFTSLRDLLWGNAVYLKEANAISVELKKKVQFQFVLLTDTL
                     YSPLPPELLPTEMEKTHEDRPFPRTVVAVEVQDLKNGATHYWSLEKLKQRLDLMREMY
                     DRAGEMASSAQDESETTVTGSDPFYDRFHWFKLVGSSPIFHGCVNERLADRTPSPTFS
                     TADSDITELADEQQDEMEDFDDEAFVDDAGSDAGTEEGSDLFSDGHDPFYDRSPWFIL
                     VGRAFVYLSNLLYPVPLIHRVAIVSEKGEVRGFLRVAVQAIAADEEAPDYGSGIRQSG
                     TAKISFDNEYFNQSDFSSVAMTRSGLSLEELRIVEGQGQSSEVITPPEEISRINDLDL
                     KSSTLLDGKMVMEGFSEEIGNHLKLGSAFTFRVTVLQASGILPEYADIFCQFNFLHRH
                     DEAFSTEPLKNNGRGSPLAFYHVQNIAVEITESFVDYIKTKPIVFEVFGHYQQHPLHL
                     QGQELNSPPQPCRRFFPPPMPLSKPVPATKLNTMSKTSLGQSMSKYDLLVWFEISELE
                     PTGEYIPAVVDHTAGLPCQGTFLLHQGIQRRITVTIIHEKGSELHWKDVRELVVGRIR
                     NKPEVDEAAVDAILSLNIISAKYLKSSHNSSRTFYRFEAVWDSSLHNSLLLNRVTPYG
                     EKIYMTLSAYLELDHCIQPAVITKDVCMVFYSRDAKISPPRSLRSLFGSGYSKSPDSN
                     RVTGIYELSLCKMSDTGSPGMQRRRRKILDTSVAYVRGEENLAGWRPRGDSLILEHQW
                     ELEKLELLHEVEKTRHFLLLRERLGDSIPKSLSDSLSPSLSSGTLSTSTSISSQISTT
                     TFESAITPSESSGYDSGDIESLVDREKELATKCLQLLTHTFNREFSQVHGSVSDCKLS
                     DISPIGRDPSESSFSSATLTPSSTCPSLVDSRSNSLDQKTPEANSRASSPCPEFEQFQ
                     IVPAVETPYLARAGKNEFLNLVPDIEEIRPSSVVSKKGYLHFKEPLYSNWAKHFVVVR
                     RPYVFIYNSDKDPVERGIINLSTAQVEYSEDQQAMVKTPNTFAVCTKHRGVLLQALND
                     KDMNDWLYAFNPLLAGTIRSKLSRRCPSQSKY"
     exon            495..571
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            572..751
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            752..817
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            818..996
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            997..1108
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            1109..1186
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            1187..1252
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            1253..1270
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            1271..1346
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            1347..1425
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            1426..1568
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            1569..1610
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            1611..1822
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            1823..1902
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            1903..1978
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            1979..2058
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            2059..2165
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            2166..2249
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            2250..2430
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            2431..2503
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            2504..2597
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            2598..2746
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            2747..2925
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            2926..3063
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            3064..3312
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            3313..3431
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            3432..3517
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            3518..3647
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            3648..3810
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            3811..3901
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            3902..4020
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            4021..4076
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            4077..4185
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            4186..4252
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            4253..4337
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            4338..4443
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            4444..4558
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            4559..4692
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            4693..4754
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            4755..4900
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            4901..5140
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            5141..5212
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            5213..5334
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            5335..5484
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            5485..5677
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            5678..5796
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     exon            5797..10855
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      10829..10834
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /note="hexamer: AATAAA"
     polyA_site      10852
                     /gene="KIF1B"
                     /gene_synonym="CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1"
                     /note="major polyA site"
ORIGIN      
        1 agtgtgacgg cagcggtcct gggaggcgcc cgcgcgcgtc ggagcagctc cccgtcctcc
       61 gcagccgtca ccgccggccg tcgccgcgcc ctggcctccc gcactcgcgc actcctgtcc
      121 gccgcccacc gcccacctcc cacctcgatg cggtgccggg ctgctgcgtg atggggctgc
      181 ggagcggcgc cctgcggctc gcggcggccg ctgctcgcgc tgaggtgcgt cggtgcccgg
      241 ccccccgcgc ccccgcgcgc cgcggctcct gttgacccgg tccgcccgtc ggtctgcagc
      301 gcggctgagg aaacttggct gtaacttcaa aagaagattt gattctttat ttctggactg
      361 catatatata tataacaagg ccattaaaat gtcgggagcc tcagtgaagg tggctgtccg
      421 ggtaaggccc ttcaattctc gagagaccag caaggaatcc aaatgcatca ttcagatgca
      481 aggcaactcg accagtatta ttaacccaaa gaatccaaag gaagctccaa agtccttcag
      541 cttcgactat tcctactggt ctcatacctc acccgaagat ccctgttttg catctcaaaa
      601 ccgtgtgtac aatgacattg gcaaggaaat gctcttacac gcctttgagg gatataatgt
      661 ctgtattttt gcctatgggc agactggtgc tggaaaatct tatacaatga tgggtaaaca
      721 agaagaaagc caggctggca tcattccaca gttatgtgaa gaactttttg agaaaatcaa
      781 tgacaactgt aatgaagaaa tgtcttactc tgtagaggtg agctacatgg aaatttactg
      841 tgaaagagta cgagatttgc tgaatccaaa aaacaagggt aatttgcgtg tgcgtgaaca
      901 cccacttctt ggaccctatg tggaggatct gtccaagttg gcagttactt cctacacaga
      961 cattgctgac ctcatggatg ctgggaacaa agccaggaca gtggcagcta caaacatgaa
     1021 tgaaacaagt agccgttccc acgctgtgtt tacgattgtt ttcacccaga agaaacacga
     1081 taatgagacc aacctttcca ctgagaaggt cagtaaaatc agcttggtgg atctagcagg
     1141 aagtgaacga gctgattcaa ctggtgccaa agggactcga ttaaaggaag gagcaaatat
     1201 taataagtct cttacaactt tgggcaaagt catttcagcc ttggccgagg tggataactg
     1261 cactagcaag agtaaaaaga agaagaaaac agattttatt ccctacaggg attctgtact
     1321 tacttggctc cttcgagaaa atttaggtgg caattctcgg actgcaatgg ttgctgctct
     1381 gagccccgcg gatatcaact acgatgagac tttgagcact ctgagatatg cagatcgtgc
     1441 aaaacaaatt aaatgcaatg ctgttatcaa tgaggacccc aatgccaaac tggttcgtga
     1501 attaaaggag gaggtgacac ggctgaagga ccttcttcgt gctcagggcc tgggagatat
     1561 tattgatatt gatccattga tcgatgatta ctctggaagt ggaagcaaat atctgaaaga
     1621 ttttcagaac aataagcata gatacttgct agcctctgag aatcaacgcc ctggccattt
     1681 ttccacagca tccatggggt ccctcacttc atccccatct tcctgctcac tcagtagtca
     1741 ggtgggcttg acgtctgtga ccagtattca agagaggatc atgtctacac ctggaggaga
     1801 ggaagctatt gaacgtttaa aggaatcaga gaagatcatt gctgagttga atgaaacttg
     1861 ggaagagaag cttcgtaaaa cagaggccat cagaatggag agagaggctt tgttggctga
     1921 gatgggagtt gccattcggg aagatggagg aaccctaggg gttttctcac ctaaaaagac
     1981 cccacatctt gttaacctca atgaagaccc actaatgtct gagtgcctac tttattacat
     2041 caaagatgga attacaaggg ttggccaagc agatgctgag cggcgccagg acatagtgct
     2101 gagcggggct cacattaaag aagagcattg tatcttccgg agtgagagaa gcaacagcgg
     2161 ggaagttatc gtgaccttag agccctgtga gcgctcagaa acctacgtaa atggcaagag
     2221 ggtgtcccag cctgttcagc tgcgctcagg aaaccgtatc atcatgggta aaaaccatgt
     2281 tttccgcttt aaccacccgg aacaagcacg agctgagcga gagaagactc cttctgctga
     2341 gaccccctct gagcctgtgg actggacatt tgcccagagg gagcttctgg aaaaacaagg
     2401 aattgatatg aaacaagaga tggagaaaag gctacaggaa atggagatct tatacaaaaa
     2461 ggagaaggaa gaagcagatc ttcttttgga gcagcagaga ctggactatg agagtaaatt
     2521 gcaggccttg cagaagcagg ttgaaacccg atctctggct gcagaaacaa ctgaagagga
     2581 ggaagaagag gaagaagttc cttggacaca gcatgaattt gagttggccc aatgggcctt
     2641 ccggaaatgg aagtctcatc agtttacttc attacgggac ttactctggg gcaatgccgt
     2701 gtacctaaag gaggccaatg ccatcagtgt ggaactgaaa aagaaggtgc agtttcagtt
     2761 tgttctgctg actgacacac tgtactcccc tttgcctcct gaattacttc ccactgagat
     2821 ggaaaaaact catgaggaca ggcctttccc tcgcacagtg gtagcagtag aagtccagga
     2881 tttgaagaat ggagcaacac actattggtc tttggagaaa ctcaagcaga ggctggattt
     2941 gatgcgagag atgtatgata gggcagggga gatggcctcc agtgcccaag acgaaagcga
     3001 aaccactgtg actggcagcg atcccttcta tgatcggttc cactggttca aacttgtggg
     3061 gagctccccc attttccacg gctgtgtgaa cgagcgcctt gccgaccgca caccctcccc
     3121 cactttttcc acggccgatt ccgacatcac tgagctggct gacgagcagc aagatgagat
     3181 ggaggatttt gatgatgagg cattcgtgga tgacgccggc tctgacgcag ggacggagga
     3241 gggatcagat ctcttcagtg acgggcatga cccgttttac gaccgatccc cttggttcat
     3301 tttagtggga agggcatttg tttacctgag caatctgctg tatcccgtgc ccctgatcca
     3361 cagggtggcc atcgtcagtg agaaaggtga agtgcgggga tttctgcgtg tggctgtaca
     3421 ggccatcgca gcggatgaag aagctcctga ttatggctct ggaattcgac agtcaggaac
     3481 agctaaaata tcttttgata atgaatactt taatcagagt gacttttcgt ctgttgcaat
     3541 gactcgttct ggtctgtcct tggaggagtt gaggattgtg gaaggacagg gtcagagttc
     3601 tgaggtcatc actcctccag aagaaatcag tcgaattaat gacttggatt tgaagtcaag
     3661 cactttgctg gatggtaaga tggtaatgga agggttttct gaagagattg gcaaccacct
     3721 gaaactgggc agtgccttca ctttccgagt aacagtgttg caggccagtg gaatcctccc
     3781 agagtatgca gatatcttct gtcagttcaa ctttttgcat cgccatgatg aagcattctc
     3841 cacggagccc ctcaaaaaca atggcagagg aagtcccctg gccttttatc atgtgcagaa
     3901 tattgcagtg gagatcactg aatcatttgt ggattacatc aaaaccaagc ctattgtatt
     3961 tgaagtcttt gggcattatc agcagcaccc acttcatctg caaggacagg agcttaacag
     4021 tccgcctcag ccgtgccgcc gattcttccc tccacccatg ccactgtcca agccagttcc
     4081 agccaccaag ttaaacacga tgagcaaaac cagccttggc cagagcatga gcaagtatga
     4141 cctcctggtt tggtttgaga tcagtgaact ggagcctaca ggagagtata tcccagctgt
     4201 ggttgaccac acagcaggct tgccttgcca ggggacattt ttgcttcatc agggcatcca
     4261 gcgaaggatc acagtgacca ttatccatga gaaggggagc gagctccatt ggaaagatgt
     4321 tcgtgaactg gtggtaggtc gtattcggaa taagcctgag gtggatgaag ctgcagttga
     4381 tgccatcctc tccctaaata ttatttctgc caagtacctg aagtcttccc acaactctag
     4441 caggaccttc taccgctttg aggctgtgtg ggatagctct ctgcataact cccttcttct
     4501 gaaccgagtg acaccctatg gagaaaagat ctacatgacc ttgtcggcct acctagagct
     4561 ggatcattgc atccagccgg ctgtcatcac caaggatgtg tgcatggtct tctactcccg
     4621 agatgccaag atctcaccac cacgctctct gcgtagcctc tttggcagcg gctactcaaa
     4681 gtcaccagat tcgaatcgag tcactggcat ttacgaactc agcttatgca aaatgtcaga
     4741 cacaggtagt ccaggtatgc agagaaggag aagaaaaatc ttagatacgt cagtggcata
     4801 tgtgcgggga gaagagaact tagcaggctg gcggccccgt ggagacagcc tcatccttga
     4861 gcaccagtgg gagctggaga agctggagct cctacatgag gtggaaaaaa cccgccactt
     4921 tttgctgctg cgtgagagac ttggtgacag catccccaaa tccctgagcg actcgttatc
     4981 ccccagcctc agcagtggga ccctcagcac ctccaccagt atctcctctc agatctcaac
     5041 cactaccttt gaaagcgcca tcacacctag cgagagcagt ggctatgatt caggagacat
     5101 cgaaagcctg gtggaccgag agaaagagct ggctaccaag tgcctgcaac ttctcaccca
     5161 cactttcaac agagaattca gccaggtgca cggcagcgtc agtgactgta agttgtctga
     5221 tatctctcca attggacggg atccctctga gtccagtttc agcagtgcca ccctcactcc
     5281 ctcctccacc tgtccctctc tggtagactc taggagcaac tctctggatc agaagacccc
     5341 agaagccaat tcccgggcct ctagtccctg cccagaattt gaacagtttc agattgtccc
     5401 agctgtggaa acaccatatt tggcccgagc aggaaaaaac gaatttctca atcttgttcc
     5461 agatattgaa gaaattagac caagctcagt ggtctctaag aaaggatacc ttcatttcaa
     5521 ggagcctctt tacagtaact gggctaaaca ttttgttgtc gtccgtcggc cttatgtctt
     5581 catctataac agtgacaaag accctgtgga gcgtggaatc attaacctgt ccacagcaca
     5641 ggtggagtac agtgaggacc agcaggccat ggtgaagaca ccaaacacct ttgctgtctg
     5701 cacaaagcac cgtggggtcc ttttgcaggc cctcaatgac aaagacatga acgactggtt
     5761 gtatgccttc aacccacttc tagctggcac aatacggtca aagctttccc gcagatgccc
     5821 gagccagtcg aaatactaag tgactctgcc gagtgccctc actcgccttc gagagataaa
     5881 gaaagcgtta cctctcattt ctctttgtga ttcttgacgg tgactcttgt atgtaatcct
     5941 gtggcttaac tacttctccc tccttgtcca gcacttttct agctctcccg ttccccatct
     6001 ccattgctct gtactctttt cttttttctt gtgctgagaa tctcgttagt agcatgtggc
     6061 ctaacaaaag gaaaaaatgt ttttaaacac acacacacac acacacacac acacacacat
     6121 acacagacaa aaacacaaaa actctgaggg gatctggtga atctccaaat tattgtgggt
     6181 gtactttggc ttccttttgt atgataggtc cccatcatga ccacctctga tgtctgtgct
     6241 gctgtcacca ggcacctttg tttttcaaga caacatactt tttttttctt ttctctgttt
     6301 gtgatatcac tttaattttt cttgggtggc ttagagacta agggaggaga catctggcct
     6361 ttttagaacc tgagaggaaa aaaagagtct ttttttcccc tctgtctctt tttgccatgg
     6421 ctaatccctg catttccatt cagggaaaag gtggtagtga gcatagaact gcaacagtta
     6481 tattctgagt caaagttggg gctttttacg gcataattat ggaattttta tttactggta
     6541 gagaggagac gagaggcttt ttcagtgggc ctgggacagt ggctgctctt gactttgtgt
     6601 gaagggaaat gccaaggatg cttctggtgg acttcagggg accccagggt ttggccgtgg
     6661 gccgtgatgg cagcaggcgg tgggatgctt gtagctcctc acagcaggat tcctgcccac
     6721 tgttttttct ctgttgggag ggaagctctt ttctaggagt gtctcagttc tgcttttggc
     6781 attagtgatg gtggtggtac agttggaatt agtgccatgt catacacaaa tgttccacaa
     6841 ggcgggagtg tttcactttc tggtgataaa cttgatggtc attgttatga ttaagataat
     6901 gccgggcagg ccgggcacag tggctcacgc ctgtaatcca agcacttggg gaggccgagg
     6961 cgggcagatc acgagatcag gagttcaaga ccagcctggc caatatgatg aaaccccgtc
     7021 tctactaaaa atacaaaatt agtcgggtat ggtggcacat gcctgtaatt ccagctgctt
     7081 gggagcctga ggcaggagaa ctgcttgaac ccaggaggca gaggttgcag tgagccaaga
     7141 tcgcgctatt gcactccagc ctgggtgaca gagcaagact ctgcctcaga aaaaaaaaaa
     7201 aataataatg ctgggtagtg accttgtgat tgttacagct ccctttgatc aaagaaatat
     7261 agctttcagg cataaacctg gaagtctccc tctgaatcca gcagttgttt tcattgatgc
     7321 ttgtcaggtt gaagatgctt tcagtgatgc tctctatact cataaataag caaatgtggc
     7381 aggctttgct ttctggatcc caggattaaa actaaccgtg accactactc caaacaaaac
     7441 acaatatgcc taggggcacg gatgaacgtc cagggagccc gggccccagg ctttgttgcg
     7501 tgttccctgc tcctctccat ctggtgtgga aacactgccc agggagaaag gaggaagctc
     7561 actgtggaca gtcttctttc cttctgacag accaggtcat ctggcttccg agatcatcag
     7621 agaagataag tctgtctctt tcagctgcca gtaagttttc caggatgaga ggggaaaaag
     7681 aaagcctcca gtgacttcag ttgctttgcc agttgtcttg ggattgtttt acaccatcct
     7741 ttacttccct tgctcagacc tctctgtttc accattgctc aggcattcag gaaagtatct
     7801 gctcactccc acttggtgag tcctcggcct tgaggttgct gactctcagg cgttaggcag
     7861 ctggatgact tcccgcttca cgcagcaaag gccaggggct tgcgcgcctc tgcagagttg
     7921 ttgctaggga gacttgtgtc atcatccaca accttgtttc tcacttcctg gttgggctca
     7981 tctctgaaga acaggtctcc cagcttcgct ccttatcact gcattgtgaa gaggaggaaa
     8041 agtgaatcac ggagagagaa aggaaaggat agaatcacag gctgcgtctg cacctgaaaa
     8101 gtgacccgcg gaaactctat ggcggatttt ttttttaact ttcttcttcc tgttaaaaca
     8161 taggtcacta actgtgatgt tatttgtttt ctaagtggta tgtgagattt tctaatgtag
     8221 ttagaagttt cattgtctga tggacacaat atgcccttcc ggttctattc aaaccagcag
     8281 gatctgtcgg tgcttagaga tggctgcctg gactggaatc aaatctaatt tcagggaaat
     8341 gaagatggaa tttgaaggtc acttttaaaa ttaagtcatt gatgctgctg ttacagagtg
     8401 tgacagagga tccatgtctg tgacacagga cggtgggaag cctgagagag agtgaaatta
     8461 tgtgatacac tgaaatgact tttgtttttc ttctaactca tacaaaactg gtttggaaag
     8521 tctttgcttt ggaagcgtca gacattagaa caggccaaac tggactgtct gttcatagcg
     8581 tgcctgaata agaaggcctc ttagggagcc agagggagca gagtggtcgt gtcctgcgtg
     8641 ctcttcaccc tctggggcgc ccctgctgcg gctggcaggt gcagacagcc tttgctggtc
     8701 cccagcacgt ccagggtggg tgctcccttg cccgacagaa ccatccccac tgtgaggctg
     8761 tgagagattt gtggcaggaa ctgtttatga ggctctagtt gttgctgttg tggcgggaaa
     8821 gttaagaaac atagccctta aggaaaccac ctttatgtat tttcttaaag cacgccttta
     8881 aataagcaaa aactttaaaa ggcaggaaag agaattctta ggcaaattca gagaaataag
     8941 tgctagttaa tactaatcac ctcctcctct gtctctcatc ctcctttctc ccatcaaagc
     9001 aaaatatggc ctcaccacca gccccaaatc agtgctcaga ccctctctgt gtctgtgtgc
     9061 cctcctggga gtcagtcagc gctcaggcca ggactgtgca gggccagcca gcccatgcgc
     9121 tagtcaggag cacaggcaag gggtgcttgt ggcagtggcc gggcacctga gccccagctc
     9181 gttgttaaac gtgctgacgg caaggggcaa tggagtgagt ttcccaacta agaaaccact
     9241 attatatatt ttttcccttc agtcacatag acttcagaca actctcctat tttttatgga
     9301 tttttcagct catttcagat gaaggaacta agtcattgtg aactgtctct tgagatctaa
     9361 aaacaagatg acttttcctg gcacatattc caaagcaaag actttgttgc ctgctgctta
     9421 ttgtctaatt tacagggata tttaattttg tcaggtctat gtatatttat ccagctatac
     9481 ttacttgcac agtggattgg agagaaagga ttctccagtg tgcacactca tcggtactct
     9541 ttctgcattt ccctcgtgct gtgtcccgct cgggttccaa tggacagtat cagggcttgt
     9601 ttgacttagg tctttcagtt ttcctttcgg ttccctttta aaaatgtgat tgttaacctg
     9661 cctcttgaaa gattcaaccg ggtgtggtgg ctcacgcctg taatcccagc acattgggag
     9721 gccaaggcag gtggatcacc tgaggtcaga agtttgagac cagcctggcc aacatggtga
     9781 aaccccgtct ctactaaaaa tacaaaaagt agccaggcgt ggtggcgtgt gcctgtagtc
     9841 ccagctactt gggaggctga ggcaggagaa tagcttgaac ctgggaggtg gaggctgcag
     9901 tgagttgaga ctgcaccatt gcactccagc ctgggtgaca aagcaggact ccgtctcaaa
     9961 aaaaaagaaa agattcatga tgctgctgct cccagaaggt ttgctggatg tgtttacata
    10021 ggactctaac ttgtgtgcac tacagttgtt caccagggcc agtgattcac cccagtgtgt
    10081 ggccagacca tgactgtgta gcaggaatgt tttaatttgt gcttccttag taaattgaaa
    10141 tatcagctga gagattattt gctgctgtta ttcaaaaggc catttatgaa gttagtattt
    10201 gagccccata agatctttaa aaagcctcca atcatttaaa ggaagaaatc agagttgcta
    10261 taaaattcag taaaaagctc atagccaaac ggctgtgctc agatggaaag tctgagctga
    10321 ggttggtctc ttgccaaacc gtggctgttg tgtgttgttc ttcatgtctt cgagttcatt
    10381 ttttttcatt ctgcctattc tggcatcagc tcacttgagg agtccctcag ccttcttgta
    10441 tttaaggcat cgtcttagac tttgtggctc taaagtacct gtctgttgag atttcaagtc
    10501 tcttgtcacc atcctcacac atgacaacaa aacccataat gcataagtgg cctttttgaa
    10561 ccaagacttt gcaaactgat ctctcccccg tgaaggagtt gagcacatta gcaacaatgt
    10621 acattaattt tggattttca ttttcatgtt ttattttgta aatattatct gatgtttgga
    10681 gcttgagtat acagactgta aatatagttc ttgtatttgt actaattctg attcttttgc
    10741 tgtatagcct tagatgtgca atgcagacac tatctaactg tgtgtggtaa ccttgcgtca
    10801 cggagctgtt agtgaacgag gtaaaaataa taaaggtaca gccagtgcat cagaa
//
