LOCUS       NM_001029864            6377 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens KIAA1755 (KIAA1755), transcript variant 1, mRNA.
ACCESSION   NM_001029864 XM_028810
VERSION     NM_001029864.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6377)
  AUTHORS   von der Heyde,B., Emmanouilidou,A., Mazzaferro,E., Vicenzi,S.,
            Hoijer,I., Klingstrom,T., Jumaa,S., Dethlefsen,O., Snieder,H., de
            Geus,E., Ameur,A., Ingelsson,E., Allalou,A., Brooke,H.L. and den
            Hoed,M.
  TITLE     Translating GWAS-identified loci for cardiac rhythm and rate using
            an in vivo image- and CRISPR/Cas9-based approach
  JOURNAL   Sci Rep 10 (1), 11831 (2020)
   PUBMED   32678143
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6377)
  AUTHORS   den Hoed,M., Eijgelsheim,M., Esko,T., Brundel,B.J., Peal,D.S.,
            Evans,D.M., Nolte,I.M., Segre,A.V., Holm,H., Handsaker,R.E.,
            Westra,H.J., Johnson,T., Isaacs,A., Yang,J., Lundby,A., Zhao,J.H.,
            Kim,Y.J., Go,M.J., Almgren,P., Bochud,M., Boucher,G.,
            Cornelis,M.C., Gudbjartsson,D., Hadley,D., van der Harst,P.,
            Hayward,C., den Heijer,M., Igl,W., Jackson,A.U., Kutalik,Z.,
            Luan,J., Kemp,J.P., Kristiansson,K., Ladenvall,C., Lorentzon,M.,
            Montasser,M.E., Njajou,O.T., O'Reilly,P.F., Padmanabhan,S., St
            Pourcain,B., Rankinen,T., Salo,P., Tanaka,T., Timpson,N.J.,
            Vitart,V., Waite,L., Wheeler,W., Zhang,W., Draisma,H.H.,
            Feitosa,M.F., Kerr,K.F., Lind,P.A., Mihailov,E., Onland-Moret,N.C.,
            Song,C., Weedon,M.N., Xie,W., Yengo,L., Absher,D., Albert,C.M.,
            Alonso,A., Arking,D.E., de Bakker,P.I., Balkau,B., Barlassina,C.,
            Benaglio,P., Bis,J.C., Bouatia-Naji,N., Brage,S., Chanock,S.J.,
            Chines,P.S., Chung,M., Darbar,D., Dina,C., Dorr,M., Elliott,P.,
            Felix,S.B., Fischer,K., Fuchsberger,C., de Geus,E.J., Goyette,P.,
            Gudnason,V., Harris,T.B., Hartikainen,A.L., Havulinna,A.S.,
            Heckbert,S.R., Hicks,A.A., Hofman,A., Holewijn,S.,
            Hoogstra-Berends,F., Hottenga,J.J., Jensen,M.K., Johansson,A.,
            Junttila,J., Kaab,S., Kanon,B., Ketkar,S., Khaw,K.T., Knowles,J.W.,
            Kooner,A.S., Kors,J.A., Kumari,M., Milani,L., Laiho,P.,
            Lakatta,E.G., Langenberg,C., Leusink,M., Liu,Y., Luben,R.N.,
            Lunetta,K.L., Lynch,S.N., Markus,M.R., Marques-Vidal,P., Mateo
            Leach,I., McArdle,W.L., McCarroll,S.A., Medland,S.E., Miller,K.A.,
            Montgomery,G.W., Morrison,A.C., Muller-Nurasyid,M., Navarro,P.,
            Nelis,M., O'Connell,J.R., O'Donnell,C.J., Ong,K.K., Newman,A.B.,
            Peters,A., Polasek,O., Pouta,A., Pramstaller,P.P., Psaty,B.M.,
            Rao,D.C., Ring,S.M., Rossin,E.J., Rudan,D., Sanna,S., Scott,R.A.,
            Sehmi,J.S., Sharp,S., Shin,J.T., Singleton,A.B., Smith,A.V.,
            Soranzo,N., Spector,T.D., Stewart,C., Stringham,H.M., Tarasov,K.V.,
            Uitterlinden,A.G., Vandenput,L., Hwang,S.J., Whitfield,J.B.,
            Wijmenga,C., Wild,S.H., Willemsen,G., Wilson,J.F., Witteman,J.C.,
            Wong,A., Wong,Q., Jamshidi,Y., Zitting,P., Boer,J.M., Boomsma,D.I.,
            Borecki,I.B., van Duijn,C.M., Ekelund,U., Forouhi,N.G., Froguel,P.,
            Hingorani,A., Ingelsson,E., Kivimaki,M., Kronmal,R.A., Kuh,D.,
            Lind,L., Martin,N.G., Oostra,B.A., Pedersen,N.L., Quertermous,T.,
            Rotter,J.I., van der Schouw,Y.T., Verschuren,W.M., Walker,M.,
            Albanes,D., Arnar,D.O., Assimes,T.L., Bandinelli,S., Boehnke,M., de
            Boer,R.A., Bouchard,C., Caulfield,W.L., Chambers,J.C., Curhan,G.,
            Cusi,D., Eriksson,J., Ferrucci,L., van Gilst,W.H., Glorioso,N., de
            Graaf,J., Groop,L., Gyllensten,U., Hsueh,W.C., Hu,F.B.,
            Huikuri,H.V., Hunter,D.J., Iribarren,C., Isomaa,B., Jarvelin,M.R.,
            Jula,A., Kahonen,M., Kiemeney,L.A., van der Klauw,M.M.,
            Kooner,J.S., Kraft,P., Iacoviello,L., Lehtimaki,T., Lokki,M.L.,
            Mitchell,B.D., Navis,G., Nieminen,M.S., Ohlsson,C., Poulter,N.R.,
            Qi,L., Raitakari,O.T., Rimm,E.B., Rioux,J.D., Rizzi,F., Rudan,I.,
            Salomaa,V., Sever,P.S., Shields,D.C., Shuldiner,A.R., Sinisalo,J.,
            Stanton,A.V., Stolk,R.P., Strachan,D.P., Tardif,J.C.,
            Thorsteinsdottir,U., Tuomilehto,J., van Veldhuisen,D.J.,
            Virtamo,J., Viikari,J., Vollenweider,P., Waeber,G., Widen,E.,
            Cho,Y.S., Olsen,J.V., Visscher,P.M., Willer,C., Franke,L.,
            Erdmann,J., Thompson,J.R., Pfeufer,A., Sotoodehnia,N.,
            Newton-Cheh,C., Ellinor,P.T., Stricker,B.H., Metspalu,A.,
            Perola,M., Beckmann,J.S., Smith,G.D., Stefansson,K., Wareham,N.J.,
            Munroe,P.B., Sibon,O.C., Milan,D.J., Snieder,H., Samani,N.J. and
            Loos,R.J.
  CONSRTM   Global BPgen Consortium; CARDIoGRAM Consortium; PR GWAS Consortium;
            QRS GWAS Consortium; QT-IGC Consortium; CHARGE-AF Consortium
  TITLE     Identification of heart rate-associated loci and their effects on
            cardiac conduction and rhythm disorders
  JOURNAL   Nat Genet 45 (6), 621-631 (2013)
   PUBMED   23583979
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL031651.33.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 22, 2018 this sequence version replaced NM_001029864.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longer isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803613.246173.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000279024.9/ ENSP00000279024.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-238               AL031651.33        156929-157166       c
            239-436             AL031651.33        142360-142557       c
            437-1784            AL031651.33        137013-138360       c
            1785-1982           AL031651.33        135959-136156       c
            1983-2106           AL031651.33        127633-127756       c
            2107-2200           AL031651.33        124578-124671       c
            2201-2287           AL031651.33        123585-123671       c
            2288-2404           AL031651.33        122096-122212       c
            2405-2503           AL031651.33        119969-120067       c
            2504-2652           AL031651.33        118880-119028       c
            2653-2791           AL031651.33        116061-116199       c
            2792-2914           AL031651.33        114675-114797       c
            2915-3136           AL031651.33        113684-113905       c
            3137-6375           AL031651.33        106936-110174       c
            6376-6377           AL031651.33        106934-106935       c
FEATURES             Location/Qualifiers
     source          1..6377
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="20"
                     /map="20q11.23"
     gene            1..6377
                     /gene="KIAA1755"
                     /gene_synonym="quo"
                     /note="KIAA1755"
                     /db_xref="GeneID:85449"
                     /db_xref="HGNC:HGNC:29372"
     exon            1..238
                     /gene="KIAA1755"
                     /gene_synonym="quo"
                     /inference="alignment:Splign:2.1.0"
     CDS             236..3838
                     /gene="KIAA1755"
                     /gene_synonym="quo"
                     /note="isoform a is encoded by transcript variant 1;
                     RP5-1054A22.3; quattro homolog"
                     /codon_start=1
                     /product="uncharacterized protein KIAA1755 isoform a"
                     /protein_id="NP_001025035.1"
                     /db_xref="CCDS:CCDS33467.1"
                     /db_xref="GeneID:85449"
                     /db_xref="HGNC:HGNC:29372"
                     /translation="MDPPSLDTAIQHALAGLYPPFEATAPTVLGQVFRLLDSGFQGDG
                     LSFLLDFLIPAKRLCEQVREAACAPYSHCLFLHEGWPLCLRDEVVVHLAPLNPLLLRQ
                     GDFYLQVEPQEEQSVCIMIKCLSLDLCTVDKKPVPEPAYPILFTQEWLEAINSDFEGN
                     PLHNCLVASENGIAPVPWTKITSPEFVDDRPQVVNALCQAWGPLPLEALDLSSPQELH
                     QASSPDNQVLPAQSLAKGKGRTYGSKYPGLIKVEQARCGEVAFRMDEVVSQDFEGDYV
                     ALLGFSQESRGESPSREAGTSSGCTSGALEEIAGTKETPLFQKILPLSEANEGPSLGN
                     RACTKPESSEERPYNLGFRRKVNLKAPTHNSERPPQGSYMNVLEDALDCASGLRAGVS
                     QEPAASKMQGPLGNPENMVQLRPGPRQASSPRLSPASPAAAASETKIEVKTKERNGRL
                     PKPMPCPSRNTSSPEPPTPGLKFSFLRGQRQPSVTPEKASLQHNGPWKVLCSLYSPKP
                     NRAKSLGKAGTTQTKTSGPATAPSPLTEEKAALPEASAGSPERGPTLEEEPPGPEPRI
                     GALGVKVFRSRIACLPGGRDRAGRPLLLVSTTEGAWEAPWCTVSEVTKLLSYLCTIPR
                     PEDKAKGLAVLIDARRQPPQPGLVSALQATQAQVPASIRAILFLGEKEAALQLQTLPD
                     VQVEVLTSLKALSHHVDPSQLPAVLEGPFPYCHTEWVHFFQKLDPFLADLHQASSLLQ
                     ASIEEFEKADPPGGMQEATRCLSKSKELMEAVLRDPGLLGLQREGGATLARLQHDASR
                     LDFSPDVRSHLAAATALYSLVDEQLHVLVTASNSLLGKLELRVRLGRLEAAIHQVSDW
                     MEQEGRRCLQSLTPKDGSLETVEKAHAEFENFFLQAAAQYRRGLELSKQAAQLGATAR
                     GAGEAERAEFPELAAFASTQRAFQAELTHFYMAAERQRTDLETLLHLHRFCKRMTWFH
                     MDCQDLMAQLRLDKTSRVSPGDQRRLHRYLQRLASEFPAEKLAAVGLQVASLSRAGLG
                     QELWEEARIRHEEIRMLLEKALTHSSCPEAPAAHSARPERRGVAAKGQGVSVEVTSKG
                     RWDQPPLDSLGMDHLPKSYWPPGPPRGEQNRTFQAGSPPQEAGQAAEAEDGKGSHKLP
                     DPAREHLLATTFFRQQPPRQSQVPRLTGGSFSSEGTDSQTSLEDSPQTSPLASL"
     exon            239..436
                     /gene="KIAA1755"
                     /gene_synonym="quo"
                     /inference="alignment:Splign:2.1.0"
     exon            437..1784
                     /gene="KIAA1755"
                     /gene_synonym="quo"
                     /inference="alignment:Splign:2.1.0"
     exon            1785..1982
                     /gene="KIAA1755"
                     /gene_synonym="quo"
                     /inference="alignment:Splign:2.1.0"
     exon            1983..2106
                     /gene="KIAA1755"
                     /gene_synonym="quo"
                     /inference="alignment:Splign:2.1.0"
     exon            2107..2200
                     /gene="KIAA1755"
                     /gene_synonym="quo"
                     /inference="alignment:Splign:2.1.0"
     exon            2201..2287
                     /gene="KIAA1755"
                     /gene_synonym="quo"
                     /inference="alignment:Splign:2.1.0"
     exon            2288..2404
                     /gene="KIAA1755"
                     /gene_synonym="quo"
                     /inference="alignment:Splign:2.1.0"
     exon            2405..2503
                     /gene="KIAA1755"
                     /gene_synonym="quo"
                     /inference="alignment:Splign:2.1.0"
     exon            2504..2652
                     /gene="KIAA1755"
                     /gene_synonym="quo"
                     /inference="alignment:Splign:2.1.0"
     exon            2653..2791
                     /gene="KIAA1755"
                     /gene_synonym="quo"
                     /inference="alignment:Splign:2.1.0"
     exon            2792..2914
                     /gene="KIAA1755"
                     /gene_synonym="quo"
                     /inference="alignment:Splign:2.1.0"
     exon            2915..3136
                     /gene="KIAA1755"
                     /gene_synonym="quo"
                     /inference="alignment:Splign:2.1.0"
     exon            3137..6377
                     /gene="KIAA1755"
                     /gene_synonym="quo"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4076..4081
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KIAA1755"
                     /gene_synonym="quo"
                     /note="hexamer: AATAAA"
     polyA_site      4098
                     /gene="KIAA1755"
                     /gene_synonym="quo"
     regulatory      4384..4389
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KIAA1755"
                     /gene_synonym="quo"
                     /note="hexamer: AATAAA"
     polyA_site      4408
                     /gene="KIAA1755"
                     /gene_synonym="quo"
                     /note="major polyA site"
     regulatory      6350..6355
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KIAA1755"
                     /gene_synonym="quo"
                     /note="hexamer: TATAAA"
     polyA_site      6377
                     /gene="KIAA1755"
                     /gene_synonym="quo"
ORIGIN      
        1 atgtctctcg ccgtctccag cctcagtccc tctctgtctc tctctcagtc tctctccctg
       61 tcctccccgg ccgctcctcc gagatgacgc cggggtcggt gccccgggcc tgccctatcc
      121 cctggctcca gggctaggcg ggaccgaggg ctgccccaga cagacggacc cgcggaccca
      181 cagaccccgc gcccaggaga ggagccgcgc cgcccgccgc tggcagcccg tcaccatgga
      241 ccctccatcc ctcgacacag ccatccagca tgccctggcg ggcctctatc ctcctttcga
      301 ggccacagca cccaccgtcc tgggtcaggt gttccgtctc ctggactctg gcttccaggg
      361 ggatgggctg agcttccttc tggatttcct gatccctgcc aagcgcctgt gtgagcaagt
      421 gcgagaagca gcctgtgctc cctactcaca ctgcctcttc ttacacgagg gctggccact
      481 ctgtctgagg gatgaagttg tggtccactt ggcacccctc aaccctctct tattgcgcca
      541 gggtgacttc tacctccaag tggagcccca ggaggagcag tctgtctgca tcatgatcaa
      601 atgcctctcc ctggacctct gcacagtgga caagaagcct gttccagagc cagcctaccc
      661 tatacttttc acccaagaat ggctggaggc catcaacagt gactttgagg gaaatcccct
      721 acacaactgc ttggtagcat cagaaaatgg gattgcccct gtgccttgga ccaagataac
      781 cagcccagag tttgtggatg acagacccca agtagtgaat gccctctgcc aagcctgggg
      841 gccccttcca ttagaggcac tggatttgag cagccctcaa gagttgcacc aggccagctc
      901 cccagacaac caggtgcttc ctgcccagag tttggccaag ggtaagggca ggacatatgg
      961 gagcaagtat ccaggactca tcaaggtgga gcaagcccgg tgtggggagg tggctttcag
     1021 gatggacgag gtggtcagcc aggacttcga gggagactat gtggctctcc taggcttttc
     1081 ccaagagagc agaggagagt ctcccagtag ggaggcaggc acatccagtg ggtgtacttc
     1141 tggggcacta gaggagatag ctggaactaa ggaaactccc ttatttcaaa agatactgcc
     1201 tctctcagag gccaatgaag gaccttcctt gggaaatcgg gcttgcacaa agccagaaag
     1261 ctctgaggag aggccctata atttgggctt caggagaaag gtcaatctta aagcacccac
     1321 ccacaactca gaaaggccgc cccaaggctc ctacatgaat gtccttgagg acgcactgga
     1381 ctgtgcctct ggtctcaggg caggtgtctc acaagagcca gctgcctcca agatgcaggg
     1441 acctctagga aacccagaga atatggtgca gctcaggcct ggaccaagac aagcctcctc
     1501 tccccgcctg tccccagctt ctcctgcagc tgcagcctct gaaacaaaga tagaggtgaa
     1561 gaccaaagag agaaatggga gacttcccaa gcccatgccc tgccctagca gaaacacctc
     1621 ctcccctgag ccccccactc ctgggctcaa attctcattc ttgagagggc agaggcaacc
     1681 ctctgtgacc ccggagaaag cctcactcca gcacaatggg ccctggaaag tcctgtgttc
     1741 cctctactct cctaaaccca accgagccaa atctttgggg aaagctggaa caactcagac
     1801 caaaacatct ggcccagcca ctgcccccag cccactgact gaggaaaagg ctgccttgcc
     1861 agaagcttct gcaggctccc cagaaagagg ccccaccctg gaggaggagc ccccagggcc
     1921 tgagcccagg attggggctc taggtgtcaa ggttttccgc tccaggatag catgcctgcc
     1981 aggtggccgg gacagggccg ggcggcccct gcttctggtg tcaactacag agggggcctg
     2041 ggaggcacca tggtgcacag tttcagaggt caccaagcta ctgtcctacc tgtgtaccat
     2101 ccccaggcct gaagataaag ccaaggggct ggcggtcctg attgacgcca ggagacagcc
     2161 cccacagccc ggtctggtca gcgccctgca ggccacccag gctcaggtcc cagcctctat
     2221 ccgggctatt ctcttcctgg gggagaagga ggcggctctc cagctgcaga cattacctga
     2281 cgtccaggtg gaggtgctga cctcattgaa ggccctcagc caccatgtgg accccagcca
     2341 gctgcccgca gtcctggaag gccccttccc ctactgccac accgagtggg ttcatttctt
     2401 ccagaagctg gaccctttcc ttgctgacct ccaccaggcc tcttccctgc tacaagcttc
     2461 catcgaggaa ttcgagaagg ccgacccccc tggggggatg caggaggcta ccaggtgcct
     2521 gagcaagtcc aaggagctga tggaggctgt gctgagggac cccggcctac tgggcctcca
     2581 gcgggaaggt ggagccaccc tggccaggct gcagcatgat gccagcaggc tggacttcag
     2641 ccctgatgtc aggagccatc tggctgcagc cactgccttg tacagccttg tggacgagca
     2701 gcttcatgtt ctggtcaccg cttccaacag cctcctgggg aagctggagc tccgtgtccg
     2761 cctgggccgc ctggaagctg ccattcacca ggtcagcgac tggatggagc aggaaggaag
     2821 gcggtgcctg caatcactga cccccaagga tggaagtttg gagacagtgg agaaagccca
     2881 cgcagaattt gagaacttct tcctccaggc tgcagcccag taccgccgag gcctggagct
     2941 gtccaagcag gccgctcagc tgggagctac agccagaggg gctggggagg cagaacgtgc
     3001 agagttccca gagctggcag cctttgcctc tacccagcgg gccttccagg ctgagctgac
     3061 ccacttttac atggcggccg agcggcaacg cacggacctc gagacgctgc tccacctgca
     3121 ccgcttctgc aagaggatga cctggttcca catggactgt caggacctga tggcccagct
     3181 caggctggac aagacctcaa gggtcagtcc tggggaccag cgccgcctcc accgctacct
     3241 gcagcgactg gcatctgagt tccctgctga gaagctcgca gccgtggggc tgcaggtggc
     3301 ctccctgagc cgggcaggcc tgggccagga gctatgggag gaggcccgga tcaggcatga
     3361 ggagatccgg atgctcctgg agaaggcact gacccacagc tcttgcccag aggctccagc
     3421 tgctcactca gcgcgcccag aacgaagagg ggtggcagcc aagggccagg gtgtgagtgt
     3481 agaggtcact tccaagggga ggtgggatca gcctccacta gactcactgg gcatggacca
     3541 tttgccaaag tcctattggc ctcctgggcc ccccagaggg gaacagaaca gaactttcca
     3601 ggcaggctct ccaccccagg aagctggcca ggctgcagag gctgaagacg gcaaaggctc
     3661 ccacaagctg cctgaccctg cccgcgagca tttgcttgcc accaccttct tccggcagca
     3721 gccccccagg cagagccagg tccctcgcct cactgggggc agcttctcct cagaggggac
     3781 agactcacag acatcccttg aggactcacc ccagacaagt ccccttgcct ccctctagct
     3841 gagaggcccc ttcagtcgca ccagcctcca ggagcactgg gccagggccc agctggaggg
     3901 gtagctggga gctctggtca gtcccagtga gacgtcacca tggagcactg gttttacatt
     3961 ctgcctctgc tgggaggatg agaactgtcg acctgcccct ggctccagaa aactcctgga
     4021 agacccgatc ttcacccatg cagaatagca agagtgggcg tcagaaccag ggcacaataa
     4081 atggtgtgat tggctccatc cctccaggct ctcattgtgg aaagacctgt cggcacagac
     4141 ccctccagag gtctcgctcg caggcaggca gacacccacc tgcagctcag gaacatacac
     4201 agctctcccc tcgggtacga gggccagtgt tgcccttagg cagaatcctc ggggagattc
     4261 gggagtgctt ccttgtcttg gattccagga aaatggaccc tgagatgagg atttaaggat
     4321 cagtgtgttt ggtgctgatc caggaacctc tgctggggga gtaggaggcg aatctgcaaa
     4381 gggaataaag agtatgttgt caagcaaatt ttcttttttt taatttttaa aacttcattg
     4441 tattttatgt ttagagatgg ggcctcacta cattgcccag gctggtctca aactcctggg
     4501 ctcaagtgat cctcttgcct tggcctgcca aagtgctggg attgcctttt ccgcccaccc
     4561 cccccgaccc caccagagac agggtctcac tctggtgtcc aggctggagt gcagtggtgc
     4621 aatcatagcc ttaaattcct gggttcaacc aatcctccca cctcagcctc ctaagtagct
     4681 gggactacag ttatgcacca ccatgctcag cttattattt atttattttt tgtagacatg
     4741 gggtcttgct atgttgccca ggcaggctga tctcaagctc aagtgatcct ctggactcag
     4801 cctcccaaag tgctgggatt atacgtatga gccactgtgc cccaccctca tacaaatttc
     4861 catgttggca actgtagctg gatctttctg gagatctctg aaagacagca tggaatcctt
     4921 gaacaccccc tgaggcgtga ggcatccaga gcatttatct gccaaccctc aggagctggc
     4981 actcgtagac agcacgcaca gccagctcca ttggtcttgg caaagagaat tgcctcctgg
     5041 agccagaggc cggttcctgt gcttagaaag gaaggacatg tcttctgtgc tccctgtctc
     5101 acaaggcctc ttcagcaggc atgggacctt cattctcaag ttcaaggaac cctgtggaac
     5161 cttgtccttg tcctccagag agaatcctct ccgccttaga ggtccctcct ctctctcacc
     5221 tccccaccaa gcctccctga actcaatgtc ttctgtcccc ttccctgccc aacttccact
     5281 tctctatgcc cagcctctgt ggcccagtac cattggggtt ctgtgggcag ctgggtcctg
     5341 gtggttgggg accgtgggaa ggggcctatc tgtcggatct tagatggagc atccagaagc
     5401 cccacccttc atactggcca gagtggcccc tgccagcgcc tctctggagt gtcattaagc
     5461 tgaaagtgtt tgccttacct ctgcagtagg atgcattact gaagtggcct cttggtcacc
     5521 tagctctgaa ttttcctggc tccagaaaga ggctgtgggg cacaggtccc ccacaatgag
     5581 gctgtgaagg ggagagaggc aggcctgggc caggcacagg aggacaacta gggcttctca
     5641 ggagctgtct cagccaagag tcacacactt gatacctaaa atggcttcag gaatcttcca
     5701 agactgaaga cttccccagg tgtggtctag ggcctgcctg cctcagagcc atgagcagag
     5761 ccggtcaaaa ggcttcctag ggaatcctac cccagacatt aaaatagact cttggtgctg
     5821 gcaggtggct ggaatctgcg tttgtagcca agtgctcttc ctgtgtgact cagcaaagtg
     5881 ggggtgcatt tggggaacac ccggggctgg ggcctgagtc ctccacccaa agccaggttt
     5941 gattcttgca ttcccctccc tgccttccat ccagacaggc ccaaagatgc aagaggcgtt
     6001 gatcagccca tctccatcca tgcctgttgc ctcagagagg gccgacggct tttaaaatgc
     6061 tgttgccata gcaacagcat ccagccagtg ggtaccacag gcagggagcc acagaaactg
     6121 gggtgctggg atggaaactg acttgtgaga gaccacagct actgctagaa ggaagggggg
     6181 caaagcgggc acaggtaatc taagaatact tgggcgggag gagtccccaa ggttaccttg
     6241 tgcatccctc tgtccccaga aagaactgta ccccaacaat ctctcccctc actgcatccc
     6301 ctggggaaga agggaatgca gaaatgaaat gtcataatga gtaacaatgt ataaaaatat
     6361 cgaataataa cagctaa
//
