LOCUS       NM_001009880            6338 bp    mRNA    linear   PRI 21-SEP-2024
DEFINITION  Homo sapiens KIAA0930 (KIAA0930), transcript variant 2, mRNA.
ACCESSION   NM_001009880 XM_047214
VERSION     NM_001009880.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6338)
  AUTHORS   Segal,D., Maier,S., Mastromarco,G.J., Qian,W.W., Nabeel-Shah,S.,
            Lee,H., Moore,G., Lacoste,J., Larsen,B., Lin,Z.Y.,
            Selvabaskaran,A., Liu,K., Smibert,C., Zhang,Z., Greenblatt,J.,
            Peng,J., Lee,H.O., Gingras,A.C. and Taipale,M.
  TITLE     A central chaperone-like role for 14-3-3 proteins in human cells
  JOURNAL   Mol Cell 83 (6), 974-993 (2023)
   PUBMED   36931259
REFERENCE   2  (bases 1 to 6338)
  AUTHORS   Cho,N.H., Cheveralls,K.C., Brunner,A.D., Kim,K., Michaelis,A.C.,
            Raghavan,P., Kobayashi,H., Savy,L., Li,J.Y., Canaj,H., Kim,J.Y.S.,
            Stewart,E.M., Gnann,C., McCarthy,F., Cabrera,J.P., Brunetti,R.M.,
            Chhun,B.B., Dingle,G., Hein,M.Y., Huang,B., Mehta,S.B.,
            Weissman,J.S., Gomez-Sjoberg,R., Itzhak,D.N., Royer,L.A., Mann,M.
            and Leonetti,M.D.
  TITLE     OpenCell: Endogenous tagging for the cartography of human cellular
            organization
  JOURNAL   Science 375 (6585), eabi6983 (2022)
   PUBMED   35271311
REFERENCE   3  (bases 1 to 6338)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   4  (bases 1 to 6338)
  AUTHORS   Ji,X., Mukherjee,S., Landi,M.T., Bosse,Y., Joubert,P., Zhu,D.,
            Gorlov,I., Xiao,X., Han,Y., Gorlova,O., Hung,R.J., Brhane,Y.,
            Carreras-Torres,R., Christiani,D.C., Caporaso,N., Johansson,M.,
            Liu,G., Bojesen,S.E., Le Marchand,L., Albanes,D., Bickeboller,H.,
            Aldrich,M.C., Bush,W.S., Tardon,A., Rennert,G., Chen,C., Byun,J.,
            Dragnev,K.H., Field,J.K., Kiemeney,L.F., Lazarus,P.,
            Zienolddiny,S., Lam,S., Schabath,M.B., Andrew,A.S., Bertazzi,P.A.,
            Pesatori,A.C., Diao,N., Su,L., Song,L., Zhang,R., Leighl,N.,
            Johansen,J.S., Mellemgaard,A., Saliba,W., Haiman,C., Wilkens,L.,
            Fernandez-Somoano,A., Fernandez-Tardon,G., Heijden,E.H.F.M.V.,
            Kim,J.H., Davies,M.P.A., Marcus,M.W., Brunnstrom,H., Manjer,J.,
            Melander,O., Muller,D.C., Overvad,K., Trichopoulou,A., Tumino,R.,
            Goodman,G.E., Cox,A., Taylor,F., Woll,P., Wichmann,E., Muley,T.,
            Risch,A., Rosenberger,A., Grankvist,K., Johansson,M., Shepherd,F.,
            Tsao,M.S., Arnold,S.M., Haura,E.B., Bolca,C., Holcatova,I.,
            Janout,V., Kontic,M., Lissowska,J., Mukeria,A., Ognjanovic,S.,
            Orlowski,T.M., Scelo,G., Swiatkowska,B., Zaridze,D., Bakke,P.,
            Skaug,V., Butler,L.M., Offit,K., Srinivasan,P., Bandlamudi,C.,
            Hellmann,M.D., Solit,D.B., Robson,M.E., Rudin,C.M., Stadler,Z.K.,
            Taylor,B.S., Berger,M.F., Houlston,R., McLaughlin,J., Stevens,V.,
            Nickle,D.C., Obeidat,M., Timens,W., Artigas,M.S., Shete,S.,
            Brenner,H., Chanock,S., Brennan,P., McKay,J.D. and Amos,C.I.
  TITLE     Protein-altering germline mutations implicate novel genes related
            to lung cancer development
  JOURNAL   Nat Commun 11 (1), 2220 (2020)
   PUBMED   32393777
  REMARK    GeneRIF: Protein-altering germline mutations implicate novel genes
            related to lung cancer development.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6338)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   6  (bases 1 to 6338)
  AUTHORS   Couzens,A.L., Knight,J.D., Kean,M.J., Teo,G., Weiss,A.,
            Dunham,W.H., Lin,Z.Y., Bagshaw,R.D., Sicheri,F., Pawson,T.,
            Wrana,J.L., Choi,H. and Gingras,A.C.
  TITLE     Protein interaction network of the mammalian Hippo pathway reveals
            mechanisms of kinase-phosphatase interactions
  JOURNAL   Sci Signal 6 (302), rs15 (2013)
   PUBMED   24255178
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 6338)
  AUTHORS   Benzinger,A., Muster,N., Koch,H.B., Yates,J.R. 3rd and Hermeking,H.
  TITLE     Targeted proteomic analysis of 14-3-3 sigma, a p53 effector
            commonly silenced in cancer
  JOURNAL   Mol Cell Proteomics 4 (6), 785-795 (2005)
   PUBMED   15778465
REFERENCE   8  (bases 1 to 6338)
  AUTHORS   Jin,J., Smith,F.D., Stark,C., Wells,C.D., Fawcett,J.P.,
            Kulkarni,S., Metalnikov,P., O'Donnell,P., Taylor,P., Taylor,L.,
            Zougman,A., Woodgett,J.R., Langeberg,L.K., Scott,J.D. and Pawson,T.
  TITLE     Proteomic, functional, and domain-based analysis of in vivo 14-3-3
            binding proteins involved in cytoskeletal regulation and cellular
            organization
  JOURNAL   Curr Biol 14 (16), 1436-1450 (2004)
   PUBMED   15324660
REFERENCE   9  (bases 1 to 6338)
  AUTHORS   Collins,J.E., Wright,C.L., Edwards,C.A., Davis,M.P., Grinham,J.A.,
            Cole,C.G., Goward,M.E., Aguado,B., Mallya,M., Mokrab,Y.,
            Huckle,E.J., Beare,D.M. and Dunham,I.
  TITLE     A genome annotation-driven approach to cloning the human ORFeome
  JOURNAL   Genome Biol 5 (10), R84 (2004)
   PUBMED   15461802
REFERENCE   10 (bases 1 to 6338)
  AUTHORS   Dunham,I., Shimizu,N., Roe,B.A., Chissoe,S., Hunt,A.R.,
            Collins,J.E., Bruskiewich,R., Beare,D.M., Clamp,M., Smink,L.J.,
            Ainscough,R., Almeida,J.P., Babbage,A., Bagguley,C., Bailey,J.,
            Barlow,K., Bates,K.N., Beasley,O., Bird,C.P., Blakey,S.,
            Bridgeman,A.M., Buck,D., Burgess,J., Burrill,W.D., O'Brien,K.P. et
            al.
  TITLE     The DNA sequence of human chromosome 22
  JOURNAL   Nature 402 (6761), 489-495 (1999)
   PUBMED   10591208
  REMARK    Erratum:[Nature 2000 Apr 20;404(6780):904]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL008718.23, AI830875.1, BC053595.1 and AK025608.1.
            
            On May 20, 2020 this sequence version replaced NM_001009880.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR and
            coding region compared to variant 1. The resulting isoform (b) is
            shorter and has a distinct N-terminus compared to isoform a.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038196.1740185.1,
                                           SRR7346977.2402639.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000336156.10/ ENSP00000336720.4
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-125               AL008718.23        62428-62552         c
            126-470             AI830875.1         69-413
            471-2265            BC053595.1         340-2134
            2266-2753           AK025608.1         1730-2217
            2754-6338           AL008718.23        13902-17486         c
FEATURES             Location/Qualifiers
     source          1..6338
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="22"
                     /map="22q13.31"
     gene            1..6338
                     /gene="KIAA0930"
                     /gene_synonym="C22orf9; LSC3"
                     /note="KIAA0930"
                     /db_xref="GeneID:23313"
                     /db_xref="HGNC:HGNC:1314"
                     /db_xref="MIM:619709"
     exon            1..255
                     /gene="KIAA0930"
                     /gene_synonym="C22orf9; LSC3"
                     /inference="alignment:Splign:2.1.0"
     CDS             192..1406
                     /gene="KIAA0930"
                     /gene_synonym="C22orf9; LSC3"
                     /note="isoform b is encoded by transcript variant 2"
                     /codon_start=1
                     /product="uncharacterized protein KIAA0930 isoform b"
                     /protein_id="NP_001009880.1"
                     /db_xref="CCDS:CCDS33665.1"
                     /db_xref="GeneID:23313"
                     /db_xref="HGNC:HGNC:1314"
                     /db_xref="MIM:619709"
                     /translation="MLRAIAEERGRLSLRREVCGLGCFKDDRIVFWTWMFSTYFMEKW
                     APRQDDMLFYVRRKLAYSGSESGADGRKAAEPEVEVEVYRRDSKKLPGLGDPDIDWEE
                     SVCLNLILQKLDYMVTCAVCTRADGGDIHIHKKKSQQVFASPSKHPMDSKGEESKISY
                     PNIFFMIDSFEEVFSDMTVGEGEMVCVELVASDKTNTFQGVIFQGSIRYEALKKVYDN
                     RVSVAARMAQKMSFGFYKYSNMEFVRMKGPQGKGHAEMAVSRVSTGDTSPCGTEEDSS
                     PASPMHERVTSFSTPPTPERNNRPAFFSPSLKRKVPRNRIAEMKKSHSANDSEEFFRE
                     DDGGADLHNATNLRSRSLSGTGRSLVGSWLKLNRADGNFLLYAHLTYVTLPLHRILTD
                     ILEVRQKPILMT"
     exon            256..407
                     /gene="KIAA0930"
                     /gene_synonym="C22orf9; LSC3"
                     /inference="alignment:Splign:2.1.0"
     exon            408..527
                     /gene="KIAA0930"
                     /gene_synonym="C22orf9; LSC3"
                     /inference="alignment:Splign:2.1.0"
     exon            528..605
                     /gene="KIAA0930"
                     /gene_synonym="C22orf9; LSC3"
                     /inference="alignment:Splign:2.1.0"
     exon            606..707
                     /gene="KIAA0930"
                     /gene_synonym="C22orf9; LSC3"
                     /inference="alignment:Splign:2.1.0"
     exon            708..848
                     /gene="KIAA0930"
                     /gene_synonym="C22orf9; LSC3"
                     /inference="alignment:Splign:2.1.0"
     exon            849..1043
                     /gene="KIAA0930"
                     /gene_synonym="C22orf9; LSC3"
                     /inference="alignment:Splign:2.1.0"
     exon            1044..1206
                     /gene="KIAA0930"
                     /gene_synonym="C22orf9; LSC3"
                     /inference="alignment:Splign:2.1.0"
     exon            1207..1365
                     /gene="KIAA0930"
                     /gene_synonym="C22orf9; LSC3"
                     /inference="alignment:Splign:2.1.0"
     exon            1366..6338
                     /gene="KIAA0930"
                     /gene_synonym="C22orf9; LSC3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2730..2735
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KIAA0930"
                     /gene_synonym="C22orf9; LSC3"
                     /note="hexamer: ATTAAA"
     polyA_site      2754
                     /gene="KIAA0930"
                     /gene_synonym="C22orf9; LSC3"
                     /note="major polyA site"
     regulatory      6318..6323
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KIAA0930"
                     /gene_synonym="C22orf9; LSC3"
                     /note="hexamer: ATTAAA"
     polyA_site      6338
                     /gene="KIAA0930"
                     /gene_synonym="C22orf9; LSC3"
ORIGIN      
        1 ggaggtgcgc tcgccggtgc tgtgtttggc gggtggtggc ggcggcggcg gcgacggcga
       61 cgcgcacaga ggcggactgt ggcttccttg gtgctcgcgg cgggctgcgg gccgggccgc
      121 ccgccctccc cgccgccgcc gcccccgagc ctgcgggcgg cgccgaggcc gaggagcgct
      181 cgctgcagca catgctgcgt gccatagcgg aggagcgcgg ccgtcttagc ctgcgccgcg
      241 aggtctgcgg cctcgggtgc ttcaaggatg accgcatcgt cttctggact tggatgttct
      301 ccacctactt catggagaaa tgggctcccc ggcaggacga catgcttttc tatgtgcgcc
      361 ggaagctggc gtactccggc agcgaaagcg gtgcagacgg gaggaaggca gctgagcctg
      421 aggtggaggt ggaggtgtac cggcgggact ccaagaagct gccaggcctg ggagaccctg
      481 acatcgactg ggaggagagc gtctgcctga atctcatcct gcagaagctg gactacatgg
      541 tgacctgtgc ggtgtgcaca cgtgctgacg gcggggacat tcacatccat aagaagaaat
      601 ctcagcaagt gttcgcgtcc cccagtaaac accccatgga cagcaagggg gaggagtcca
      661 agatcagcta ccccaacatc ttcttcatga ttgacagctt cgaggaggtg ttcagcgaca
      721 tgaccgtagg ggaaggagag atggtctgtg tggagctggt ggctagtgac aaaaccaaca
      781 cgttccaggg ggtcatcttt cagggctcca tccgctacga ggcgctcaag aaggtgtatg
      841 acaaccgggt gagcgtggcc gcccgcatgg cacagaagat gtcgtttggc ttctacaagt
      901 acagcaacat ggagtttgtg cgcatgaagg gcccccaggg caagggccac gccgagatgg
      961 cggtcagccg agtgtctaca ggtgacacat ccccctgtgg gactgaagag gactccagcc
     1021 cagcttcgcc catgcacgag cgggtgacct ccttcagcac accccccacc ccagaacgga
     1081 acaaccggcc tgccttcttc tccccatccc tcaagaggaa ggtgccccgg aaccggatcg
     1141 ctgagatgaa gaagtcgcac tcggccaacg acagcgagga gttcttccgg gaggacgacg
     1201 gtggagccga tctgcacaat gcaaccaacc tgcggtctcg gtccctgtcg ggcacaggac
     1261 ggtccctggt cgggtcctgg ctgaagctga acagagcaga tggaaacttc cttctctatg
     1321 cacacttaac ctacgtcacg ttgccgctgc atcggatttt aacagacatc ctggaagttc
     1381 ggcagaagcc catcctgatg acctagccgc gtgcggagcc tgcgcagagc cccggccggg
     1441 cccagccctc ggagtgctgc caagtgccta cctgtccacc gccaccgggg tctgcgatgg
     1501 cacgccagtg ctggagccgc agccaggcga ggccactcga ctcccggggc cggggccgac
     1561 tccacgaaca ccagcccaaa ctgaagtgcc tcttccctcc cctgctggcg ctgctccgcc
     1621 ctgtgccccc cgcccatcgc cccccaccca tctctggaga gccctctgca cccaaagagg
     1681 actagagatg ccgagcggcc atgagagaga gcggaaggag cagctgatgc ccagagcggg
     1741 gccagagcgg cgggtctatg ttcacgtccc cccagcagca ggcggaacca cccagccagg
     1801 gcactcagtg cattggactg tccacatgtt cttgaggaaa gccggtggaa gattctggaa
     1861 tgccgtgcgg atgaacttca gcacccgagt cagtcccagc tcatcctccc cagtttacca
     1921 ctttgttcta ataggagatg ggaacacgag aagtttgatg gctttgccct gggctgggaa
     1981 tacctcaccc acgcccagtt ccagaaaggc ctccagctga gcagacggcc ccgatcccgc
     2041 cagaacggcc ttttgcttcc agccaaagaa caccgccaac acgcacacct ccaacctggg
     2101 acatcccacg ctgggcctcg cacggaggaa cctgcagaat ttggattctg agggtagtcg
     2161 ggaggcctcg gtagccaggc agaacaggat atctgccaaa gggtgtctga tgtggggtgg
     2221 ggctggcatc ctcccaggaa ggttctaggt gggaccccgt cttctggggg cgggggtgtc
     2281 ttttcatctt ccctggtttc ctagaactca cttcctttga cggcgtgtgt tggtcccatc
     2341 tctcagacca gctcactgag gcagaggagt tgctcagagg ctcacatggg cacccccatt
     2401 ggttcgtgtg agcagctgcc cagccccagg cctgccctcg gcctggtcca gcatgaaggc
     2461 gtttccatct gcaaggatgc acggtaccct ccccgagagc aggcctgtcc cctacccaac
     2521 tgggaataaa ctggaagctg ggtctctttg ttgctatgtt tttttgtttg aagttcccag
     2581 gaatatttga ggggttccgg tgatgtgttt agggatcttc tctgtggggg aaaaggaaga
     2641 ggagggtctt gttctcccat ctgtttattc tttgggctct gggaacaggg gactactttg
     2701 gggctttctc cagacttttg tatgttgtta ttaaaagcga gctattgcat ttcattctgc
     2761 ctcagtttgc ccacctgtga aatggggctg ataccaccta cctcactgaa gtcccagggt
     2821 tcaagtgtgt ggctgggtca gggcgtggtc acccgtcatt ctgcataggt cgggttggat
     2881 gttagactcc tgggatgccc tcctccccct cgccctttgt aataacctaa tctgagaccg
     2941 tgcttggtgg ggggatgtga actttctctc tcccccagca gtgtctgctc aggcctgaca
     3001 gctcagctct gcacgatttc atgttcctaa acccatgtct tagggcagca cagagccagg
     3061 tcatgtcatg ccccaaagtg tggggacaga gcctcaggga gccccgagca tggtccagcc
     3121 ccatttgagt gctctccggg gatgccaaat gctgcttcca agtttgagtc catgtggcta
     3181 aaatacaccc atttcttcag gaactcttcc cctggttgtt ctggggatct tgggagaaac
     3241 acagccctga cagctcgtcc gtgggaagat gaggcagtcc aggttgtgag gagcacagcg
     3301 gcccgccctc tgttctcaga ggtgaggggc gggagaaggt tgtctcctct ggggccagca
     3361 tttggccaag ctcggaggct tggccagcac tgctggatgg ctcagagcaa gctgggctcc
     3421 ccgtctgtaa gatggcaaaa atgctgcccc cctcacaggg tgaccatgag gaccagtcac
     3481 agtgatgtgt gaaagggctc gctggtcaca gaaacgtgta caaatcatgc tattttagag
     3541 atcagccctc aatttgtaag gcatgtgaac agggcacgcg gtgggctggt ggtttcatag
     3601 ccgacacaca gcgcctacca tgtgcagctg cctgtccgac cccatcttac agacgagaaa
     3661 accagcacac aggcaccaag gaactgtccg gaactaacag caggggccgg cgatgggagt
     3721 caaacccagg cacgcggcct ggcctgcatg ctgagccaca tggtgctgtc cggacagatg
     3781 gacagacact cggtggagtc tgcctttctc aggccctaaa tccctctcca aagggtactt
     3841 gcgatgccgg atttaaaact tgctcagagc cacttagcca cttgagaacc agacagtaag
     3901 gtgttactcc caggtttgtt tttccaaagt aacagatgac atgtggaata aagtaataga
     3961 gtaacaagtg gcagggccag aaccagggtc cccaaagtcc tggtgttggc acatttgtac
     4021 ttcttgtaag accatcttta atttttctgg gaacacacct gccttttgtg taatgcgggg
     4081 aagactaatg catggtgaca cctagttttc ctcaacagga cacttgatcc caaaacccct
     4141 ttaagacctt aggtttcctc agcggaaaac tgtactttaa tcccaaaccc cctttaagac
     4201 atattggggc tgggcgcagt ggctcacgcc tgtaatccca gcactttggg aggctgagat
     4261 gggtggatca cctgagatca ggagttcaag accagcctga ctaacatgct gaaaccccat
     4321 gtctactaaa gatagaaaaa ttagctggac atggtggcag gcacctgtaa tcccagctac
     4381 tcggaaggct gaggaaggag aatcacttga acctagtagg cagaggttgc agtgagccga
     4441 gatcacgcca ttgcattcta gcctgggcaa cgagagcgaa actctgtctc aaaaaaaaaa
     4501 aaaaaaaaaa aaaaaaaaaa aaaaaaaaag atacattggt ctttaaaccc aaaccccctt
     4561 taaggcatgt tggtctcaag gggatttggg attgaagcac agctttctgt tgaggaaacc
     4621 taggtgtcac tttttagaac attaaaaaga aagttgtagg gtgggctttt ccatttaaag
     4681 gaatgtgatg atcctaggtt ctgatgagtg ataggtggtc tccgtttata ccctttcttc
     4741 ttttggcacc tgtaagttcc ggtagtggcc atcttacatt ctcatgtcct gctggaagtg
     4801 cctagttgcc tgcaaagcca gctaaggctt attatttcaa aagaagatta tttaaaacat
     4861 gagtgacagg tagtcagaag agaacaaaag gacgcaagat actctatagc caagtcagct
     4921 tggaggcagg atgggttgct gagtgaagtc gccgctcact tttggattct tatggactgt
     4981 gagttagtct tccctctaca cggagtcaca ggaagggtat aaatgcatgt tcctgaggtg
     5041 ccctccccca aagaatgtac ctgcactcaa accaggatct gtttttgctg ttttaatcat
     5101 aaatagacta gttagtagaa gacttttgaa gaacaaagta aaactttttt ttttcattaa
     5161 aagatgtccc agaggaaagg ccctgtgcag ccagtatatt ctaatgactg cctggaccat
     5221 gtcctaatat ggtggtttta agttgttggc caaaatcctt taaagacata cgaaacatct
     5281 gccaactttt tagcgaactt aacaggtttc actgacgttt tcctcaattt ttgaatttag
     5341 gtgggatttg ctttcatgtc ctgtttcaaa aaccaagtgt ctcttgacag cccactggtt
     5401 cttcctgtcc tcttgctcta gtctgtatca gaaagcagaa tgactgtact tttgttttac
     5461 aaacaaccac ctgataggac ggacactcca cgagataagg aaaggcacgt gcccttgagc
     5521 ttgaatggaa gcagcctctg gagggggcag ccactgccct tcgagggaga gcagctcttc
     5581 agcagtggcc agagtgccac gtgactctgc agatgacccc tgggagccgg gtgatgggca
     5641 cctgctgggg cttttgtttt ttctttttca ctggctggct tgatcctcag tggcaaaagg
     5701 acccctgagc cccttctccg agccctggag cactcctcgg gacaccgagt ggcctcaggg
     5761 ctgggttcag agctcctccc gcagggggag cctcagaagt ggaggcagct gctgatgggt
     5821 gagtttacaa cttcttatcc tgcctaaggc gagtaggcgt ttttattccg tttccagtcc
     5881 ttgagctcag cagatcaaaa taacagtgac cctgcaaccc cacagagccc gcgacacgct
     5941 cgctttcttc cccgccctgc ccctttagtc cccgctctgg aaggccaggc agtttaggtg
     6001 taaataggta tcttttatgg tttccaaatg aattatttgt gtgagagtaa ttaaatctgt
     6061 aagaaaacct gttgagattc ttcactatga attatgactt ctacaacatg tattttagca
     6121 aaaacacgat gctggcctcc actggatagc tcagtatgct gattgccagt gatagttctg
     6181 tacgcgttac caacagcgtc tttattaacc ctcttccaca tccagtggaa atcattgcta
     6241 ggcggtattt gttggttggc tgttagcttt gctttatgat ttcatgtttc ttttaaaggt
     6301 tgttttgcat gttgaatatt aaattttttt tttctgtg
//
