LOCUS       NM_024874               4777 bp    mRNA    linear   PRI 05-APR-2024
DEFINITION  Homo sapiens KIAA0319 like (KIAA0319L), mRNA.
ACCESSION   NM_024874
VERSION     NM_024874.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4777)
  AUTHORS   Fu,Y., Choudhary,D., Liu,N., Moon,Y., Abdubek,P., Sweezy,L.,
            Rosconi,M., Palackal,N. and Pyles,E.
  TITLE     Comprehensive biophysical characterization of AAV-AAVR interaction
            uncovers serotype- and pH-dependent interaction
  JOURNAL   J Pharm Biomed Anal 234, 115562 (2023)
   PUBMED   37441888
  REMARK    GeneRIF: Comprehensive biophysical characterization of AAV-AAVR
            interaction uncovers serotype- and pH-dependent interaction.
REFERENCE   2  (bases 1 to 4777)
  AUTHORS   Xia,M., Zhao,F., Zhang,Y., Zheng,Z., Zhou,Y. and Liu,T.
  TITLE     Identification of diagnostic markers and immune cell infiltration
            characteristics in antineutrophil cytoplasmic antibody-associated
            vasculitis by weighted gene co-expression network analysis
  JOURNAL   Eur J Med Res 27 (1), 37 (2022)
   PUBMED   35246248
  REMARK    GeneRIF: Identification of diagnostic markers and immune cell
            infiltration characteristics in antineutrophil cytoplasmic
            antibody-associated vasculitis by weighted gene co-expression
            network analysis.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4777)
  AUTHORS   Guidi,L.G., Holloway,Z.G., Arnoult,C., Ray,P.F., Monaco,A.P.,
            Molnar,Z. and Velayos-Baeza,A.
  TITLE     AU040320 deficiency leads to disruption of acrosome biogenesis and
            infertility in homozygous mutant mice
  JOURNAL   Sci Rep 8 (1), 10379 (2018)
   PUBMED   29991750
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4777)
  AUTHORS   Dudek,A.M., Pillay,S., Puschnik,A.S., Nagamine,C.M., Cheng,F.,
            Qiu,J., Carette,J.E. and Vandenberghe,L.H.
  TITLE     An Alternate Route for Adeno-associated Virus (AAV) Entry
            Independent of AAV Receptor
  JOURNAL   J Virol 92 (7), e02213-17 (2018)
   PUBMED   29343568
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4777)
  AUTHORS   Nickells,R.W., Schmitt,H.M., Maes,M.E. and Schlamp,C.L.
  TITLE     AAV2-Mediated Transduction of the Mouse Retina After Optic Nerve
            Injury
  JOURNAL   Invest Ophthalmol Vis Sci 58 (14), 6091-6104 (2017)
   PUBMED   29204649
  REMARK    GeneRIF: Optic nerve damage may change retinal architecture to
            allow greater penetration of an AAV2 virus to transduce several
            additional cell types in the inner nuclear layer.
REFERENCE   6  (bases 1 to 4777)
  AUTHORS   Song,G., Yan,J., Li,G. and Chen,Z.J.
  TITLE     Association between KIAA0319L, PXK and JAZF1 gene polymorphisms and
            unexplained recurrent pregnancy loss in Chinese Han couples
  JOURNAL   Reprod Biomed Online 30 (3), 275-280 (2015)
   PUBMED   25596907
  REMARK    GeneRIF: genetic association study in Han population in China: Data
            suggest an SNP in PXK [rs2176082(C/T); but not rs6445975(G/T)] is
            associated with recurrent pregnancy loss; SNPs in KIAA0319L
            [rs2275247(A/G)] or JAZF1 [rs1635852(C/T)] are not associated.
REFERENCE   7  (bases 1 to 4777)
  AUTHORS   Martin,J.E., Assassi,S., Diaz-Gallo,L.M., Broen,J.C., Simeon,C.P.,
            Castellvi,I., Vicente-Rabaneda,E., Fonollosa,V., Ortego-Centeno,N.,
            Gonzalez-Gay,M.A., Espinosa,G., Carreira,P., Camps,M., Sabio,J.M.,
            D'alfonso,S., Vonk,M.C., Voskuyl,A.E., Schuerwegh,A.J., Kreuter,A.,
            Witte,T., Riemekasten,G., Hunzelmann,N., Airo,P., Beretta,L.,
            Scorza,R., Lunardi,C., Van Laar,J., Chee,M.M., Worthington,J.,
            Herrick,A., Denton,C., Fonseca,C., Tan,F.K., Arnett,F., Zhou,X.,
            Reveille,J.D., Gorlova,O., Koeleman,B.P., Radstake,T.R., Vyse,T.,
            Mayes,M.D., Alarcon-Riquelme,M.E. and Martin,J.
  CONSRTM   Spanish Scleroderma Group; SLEGEN consortium; U.S. Scleroderma GWAS
            group; BIOLUPUS
  TITLE     A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS
            reveals new shared susceptibility loci
  JOURNAL   Hum Mol Genet 22 (19), 4021-4029 (2013)
   PUBMED   23740937
  REMARK    GeneRIF: Results identify KIAA0319L as novel susceptibility loci
            for Systemic sclerosis (SSc) and systemic lupus erythematosus
            (SLE). KIAA0319L was overexpressed in peripheral blood cells of SSc
            and SLE patients compared with healthy controls.
REFERENCE   8  (bases 1 to 4777)
  AUTHORS   Poon,M.W., Tsang,W.H., Chan,S.O., Li,H.M., Ng,H.K. and Waye,M.M.
  TITLE     Dyslexia-associated kiaa0319-like protein interacts with axon
            guidance receptor nogo receptor 1
  JOURNAL   Cell Mol Neurobiol 31 (1), 27-35 (2011)
   PUBMED   20697954
  REMARK    GeneRIF: Kiaa0319-like protein interacts with Nogo Receptor 1,
            supporting the idea that Kiaa0319-like protein participates in axon
            guidance.
REFERENCE   9  (bases 1 to 4777)
  AUTHORS   Yoshida,T., Kato,K., Yokoi,K., Oguri,M., Watanabe,S., Metoki,N.,
            Yoshida,H., Satoh,K., Aoyagi,Y., Nishigaki,Y., Nozawa,Y. and
            Yamada,Y.
  TITLE     Association of genetic variants with chronic kidney disease in
            individuals with different lipid profiles
  JOURNAL   Int J Mol Med 24 (2), 233-246 (2009)
   PUBMED   19578796
  REMARK    GeneRIF: Observational study of gene-disease association and
            gene-environment interaction. (HuGE Navigator)
REFERENCE   10 (bases 1 to 4777)
  AUTHORS   Couto,J.M., Gomez,L., Wigg,K., Cate-Carter,T., Archibald,J.,
            Anderson,B., Tannock,R., Kerr,E.N., Lovett,M.W., Humphries,T. and
            Barr,C.L.
  TITLE     The KIAA0319-like (KIAA0319L) gene on chromosome 1p34 as a
            candidate for reading disabilities
  JOURNAL   J Neurogenet 22 (4), 295-313 (2008)
   PUBMED   19085271
  REMARK    GeneRIF: KIAA0319L remains an intriguing positional and functional
            candidate for RD, especially when considered alongside the
            supporting evidence for its homolog KIAA0319 on chromosome 6p.
            GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DC369564.1, BC014530.1 and
            AL834315.1.
            
            On Nov 23, 2018 this sequence version replaced NM_024874.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038197.1204744.1,
                                           SRR18074969.1479152.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000325722.8/ ENSP00000318406.3
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-482               DC369564.1         36-517
            483-4185            BC014530.1         448-4150
            4186-4777           AL834315.1         3053-3644
FEATURES             Location/Qualifiers
     source          1..4777
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p34.3"
     gene            1..4777
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /note="KIAA0319 like"
                     /db_xref="GeneID:79932"
                     /db_xref="HGNC:HGNC:30071"
                     /db_xref="MIM:613535"
     exon            1..197
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /inference="alignment:Splign:2.1.0"
     exon            198..367
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /inference="alignment:Splign:2.1.0"
     CDS             226..3375
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /note="polycystic kidney disease 1-related;
                     adeno-associated virus receptor; AAV receptor like"
                     /codon_start=1
                     /product="dyslexia-associated protein KIAA0319-like
                     protein"
                     /protein_id="NP_079150.3"
                     /db_xref="CCDS:CCDS390.1"
                     /db_xref="GeneID:79932"
                     /db_xref="HGNC:HGNC:30071"
                     /db_xref="MIM:613535"
                     /translation="MEKRLGVKPNPASWILSGYYWQTSAKWLRSLYLFYTCFCFSVLW
                     LSTDASESRCQQGKTQFGVGLRSGGENHLWLLEGTPSLQSCWAACCQDSACHVFWWLE
                     GMCIQADCSRPQSCRAFRTHSSNSMLVFLKKFQTADDLGFLPEDDVPHLLGLGWNWAS
                     WRQSPPRAALRPAVSSSDQQSLIRKLQKRGSPSDVVTPIVTQHSKVNDSNELGGLTTS
                     GSAEVHKAITISSPLTTDLTAELSGGPKNVSVQPEISEGLATTPSTQQVKSSEKTQIA
                     VPQPVAPSYSYATPTPQASFQSTSAPYPVIKELVVSAGESVQITLPKNEVQLNAYVLQ
                     EPPKGETYTYDWQLITHPRDYSGEMEGKHSQILKLSKLTPGLYEFKVIVEGQNAHGEG
                     YVNVTVKPEPRKNRPPIAIVSPQFQEISLPTTSTVIDGSQSTDDDKIVQYHWEELKGP
                     LREEKISEDTAILKLSKLVPGNYTFSLTVVDSDGATNSTTANLTVNKAVDYPPVANAG
                     PNQVITLPQNSITLFGNQSTDDHGITSYEWSLSPSSKGKVVEMQGVRTPTLQLSAMQE
                     GDYTYQLTVTDTIGQQATAQVTVIVQPENNKPPQADAGPDKELTLPVDSTTLDGSKSS
                     DDQKIISYLWEKTQGPDGVQLENANSSVATVTGLQVGTYVFTLTVKDERNLQSQSSVN
                     VIVKEEINKPPIAKITGNVVITLPTSTAELDGSKSSDDKGIVSYLWTRDEGSPAAGEV
                     LNHSDHHPILFLSNLVEGTYTFHLKVTDAKGESDTDRTTVEVKPDPRKNNLVEIILDI
                     NVSQLTERLKGMFIRQIGVLLGVLDSDIIVQKIQPYTEQSTKMVFFVQNEPPHQIFKG
                     HEVAAMLKSELRKQKADFLIFRALEVNTVTCQLNCSDHGHCDSFTKRCICDPFWMENF
                     IKVQLRDGDSNCEWSVLYVIIATFVIVVALGILSWTVICCCKRQKGKPKRKSKYKILD
                     ATDQESLELKPTSRAGIKQKGLLLSSSLMHSESELDSDDAIFTWPDREKGKLLHGQNG
                     SVPNGQTPLKARSPREEIL"
     exon            368..891
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /inference="alignment:Splign:2.1.0"
     exon            892..1138
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /inference="alignment:Splign:2.1.0"
     exon            1139..1240
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /inference="alignment:Splign:2.1.0"
     exon            1241..1338
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /inference="alignment:Splign:2.1.0"
     exon            1339..1426
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /inference="alignment:Splign:2.1.0"
     exon            1427..1519
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /inference="alignment:Splign:2.1.0"
     exon            1520..1652
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /inference="alignment:Splign:2.1.0"
     exon            1653..1881
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /inference="alignment:Splign:2.1.0"
     exon            1882..2005
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /inference="alignment:Splign:2.1.0"
     exon            2006..2138
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /inference="alignment:Splign:2.1.0"
     exon            2139..2287
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /inference="alignment:Splign:2.1.0"
     exon            2288..2439
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /inference="alignment:Splign:2.1.0"
     exon            2440..2578
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /inference="alignment:Splign:2.1.0"
     exon            2579..2738
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /inference="alignment:Splign:2.1.0"
     exon            2739..2881
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /inference="alignment:Splign:2.1.0"
     exon            2882..3004
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /inference="alignment:Splign:2.1.0"
     exon            3005..3095
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /inference="alignment:Splign:2.1.0"
     exon            3096..3187
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /inference="alignment:Splign:2.1.0"
     exon            3188..4777
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4755..4760
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /note="hexamer: ATTAAA"
     polyA_site      4777
                     /gene="KIAA0319L"
                     /gene_synonym="AAVR; AAVRL"
                     /note="major polyA site"
ORIGIN      
        1 gtttccggcc gccgtcgctg tccagggagg ctgaggcgag aggtagctgt ccgggtgggg
       61 agcccgcact accttcttcc tcttcctcct cctcctccgg gtgaggggag cgaaggttgg
      121 gggtccccga gcccatggac caggaggagg cggaggccgc cgagagccgg ggccccgcta
      181 tgtggccctg agccccgtgt actggttctg cctgtctgga gggccatgga gaagaggctg
      241 ggagtcaagc caaatcctgc ttcctggatt ttatcaggat attattggca gacatctgcg
      301 aagtggttga gaagcctgta cctgttttat acttgctttt gcttcagcgt tctgtggttg
      361 tcaacagatg ccagtgagag caggtgccag caggggaaga cacaatttgg agttggcctg
      421 agatctgggg gagaaaatca cctctggctt cttgaaggaa ccccctctct ccagtcatgt
      481 tgggctgcct gctgccagga ctctgcctgc catgtctttt ggtggctaga agggatgtgc
      541 attcaggcag actgcagcag gccccagagc tgccgggctt ttaggacaca ctcctccaat
      601 tccatgctgg tgtttttaaa aaaattccaa actgcagatg atttgggctt tctacctgaa
      661 gatgatgtac cacatcttct ggggctaggt tggaactggg catcttggag gcagagccca
      721 cccagagctg cactcagacc tgctgtatct tccagtgacc agcagagctt aatcaggaag
      781 cttcagaaga gaggtagtcc cagtgacgta gttacaccta tagtgacaca gcattctaaa
      841 gtgaatgact ccaacgaatt aggtggtctg actaccagtg gctctgcaga ggtccacaag
      901 gcgattacaa tttccagtcc cctaaccaca gacctgactg cagagctgtc tggtgggcca
      961 aagaatgtat cagtgcaacc tgaaatatca gagggtcttg ctactacgcc cagcactcaa
     1021 caagtaaaaa gttctgagaa aacccagatt gctgtccccc agccagtggc tccctcctac
     1081 agttatgcta cccctacccc ccaggcctct ttccagagca cctcagcacc atacccagtt
     1141 ataaaggaac tggtggtatc tgctggagag agtgtccaga taaccctgcc taagaatgaa
     1201 gttcaattaa atgcatatgt tctccaagaa ccacctaaag gagaaaccta cacctacgac
     1261 tggcagctga ttactcatcc tagagactac agtggagaaa tggaagggaa acattcccag
     1321 atcctcaaac tatcgaagct cactccaggc ctgtatgaat tcaaagtgat tgtagagggt
     1381 caaaatgccc atggggaagg ctatgtgaac gtgacagtca agccagagcc ccgtaagaat
     1441 cggcccccca ttgctattgt gtcacctcag ttccaggaga tctctttgcc aaccacttct
     1501 acagtcattg atggcagtca aagcactgat gatgataaaa tcgttcagta ccattgggaa
     1561 gaacttaagg ggcctctaag agaagagaag atttctgaag atacagccat attaaaacta
     1621 agtaaactcg tccctgggaa ctacactttc agcttgactg tagtagactc tgatggagct
     1681 accaactcta ctactgcaaa cctgacagtg aacaaagctg tggattaccc ccctgtggcc
     1741 aacgcaggcc ccaaccaagt gatcaccctg ccccaaaact ccatcaccct ctttgggaac
     1801 cagagcactg atgatcatgg catcaccagc tatgagtggt cactcagccc aagcagcaaa
     1861 gggaaagtgg tggagatgca gggtgttaga acaccaacct tacagctctc tgcgatgcaa
     1921 gaaggagact acacttacca gctcacagtg actgacacaa taggacagca ggccactgct
     1981 caagtgactg ttattgtgca acctgaaaac aataagcctc ctcaggcaga tgcaggccca
     2041 gataaagagc tgacccttcc tgtggatagc acaaccctgg atggcagcaa gagctcagat
     2101 gatcagaaaa ttatctcata tctctgggaa aaaacacagg gacctgatgg ggtgcagctc
     2161 gagaatgcta acagcagtgt tgctactgtg actgggctgc aagtggggac ctatgtgttc
     2221 accttgactg tcaaagatga gaggaacctg caaagccaga gctctgtgaa tgtcattgtc
     2281 aaagaagaaa taaacaaacc acctatagcc aagataactg ggaatgtggt gattacccta
     2341 cccacgagca cagcagagct ggatggctct aagtcctcag atgacaaggg aatagtcagc
     2401 tacctctgga ctcgagatga ggggagccca gcagcagggg aggtgttaaa tcactctgac
     2461 catcacccta tcctttttct ttcaaacctg gttgagggaa cctacacttt tcacctgaaa
     2521 gtgaccgatg caaagggtga gagtgacaca gaccggacca ctgtggaggt gaaacctgat
     2581 cccaggaaaa acaacctggt ggagatcatc ttggatatca acgtcagtca gctaactgag
     2641 aggctgaagg ggatgttcat ccgccagatt ggggtcctcc tgggggtgct ggattccgac
     2701 atcattgtgc aaaagattca gccgtacacg gagcagagca ccaaaatggt attttttgtt
     2761 caaaacgagc ctccccacca gatcttcaaa ggccatgagg tggcagcgat gctcaagagt
     2821 gagctgcgga agcaaaaggc agactttttg atattcagag ccttggaagt caacactgtc
     2881 acatgtcagc tgaactgttc cgaccatggc cactgtgact cgttcaccaa acgctgtatc
     2941 tgtgaccctt tttggatgga gaatttcatc aaggtgcagc tgagggatgg agacagcaac
     3001 tgtgagtgga gcgtgttata tgttatcatt gctacctttg tcattgttgt tgccttggga
     3061 atcctgtctt ggactgtgat ctgttgttgt aagaggcaaa aaggaaaacc caagaggaaa
     3121 agcaagtaca agatcctgga tgccacggat caggaaagcc tggagctgaa gccaacctcc
     3181 cgagcaggca tcaaacagaa aggccttttg ctaagtagca gcctgatgca ctccgagtca
     3241 gagctggaca gcgatgatgc catctttaca tggccagacc gagagaaggg caaactcctg
     3301 catggtcaga atggctctgt acccaacggg cagacccctc tgaaggccag gagcccgcgg
     3361 gaggagatcc tgtagccacc tggtctgtct cctcagggca gggcccagca cactgcccgg
     3421 ccagtcctcc tacctcccga gtctgcgggc agctgctgtc ccagcatctg ctggtcattt
     3481 cgccctgaca gtcccaacca gaacccctgg gacttgaatc cagagacgtc ctccaggaac
     3541 ccctcaacga agctgtgaat gaagaggttt cctctttaaa cctgtctggt gggcccccag
     3601 atatcctcac ctcagggcct cctttttttg caaactcctc ccctcccccg agggcagacc
     3661 cagccagctg ctaagctctg cagctcccca gtggacagtg tcattgtgcc cagagtgctg
     3721 caaggtgagg cctgctgtgc tgcccgcaca cctgagtgca aaaccaagca ctgtgggcat
     3781 ggtgtttccc tctctggggt agagtacgcc ctctcgctgg gcaaagagga agtggcaccc
     3841 ctcccctcac cacagatgct gagatggtag catagaaatg atggccgggc gcggtggctc
     3901 acgcctgtaa tcccagcact ttgggaggcc gaggcgggcg gatcatgagg tcaggagatc
     3961 aagaccaccc tggctaacac ggtgaaaccc catctctact aaaaataaaa aaaaaaatta
     4021 gccgggtttg gtggcgtatg cctgtaatcc cagctactcg ggaggctgag gcaggagaat
     4081 tgcttaaacc tgggaggtgg aggctgcagt gagccaagat cgtgccactg cactccagcc
     4141 tgagtgacag agcaagactc cgtcaaaaaa aaaaaaaaaa aaaaagaaat gatatctggc
     4201 ccccccttaa cactggagcc ccactccctt ctcccatccg gcccgagatt agggaggatt
     4261 gactgtgtca gggatggcgg gtggcctctc tcgctgccag ggcccttgtc agagcagcca
     4321 ggctggacag acggcctccc tcctctccat ctgaccggca cctgctgctt cggggcttag
     4381 gccaccgctc cctgtcccca gaggagatag ccccagatgg actggaatgt tgtggcatga
     4441 gagcgcatgt gtgcgatggc cccgctgtgg tcccctctct gtccctccat ctgtatgtgt
     4501 tctgtgtccc ttgcatgtgt gcgtgttaga gtgagcgcgt atgcatcaac tcattgggct
     4561 cttggctgct cacaaggcaa atttgacttg gaaagacttt catctccttg gaaccaagac
     4621 ttcctgagtc cccctcaccc tggccctgtt ccaccatggt tatctgggta ttggggaatg
     4681 gaaactttgg gggagtgact ttttaaagag acacttataa tttctactac tgcactactg
     4741 tccattgtgg gatgattaaa catggtattt aactgtg
//
