LOCUS       NM_001126063             679 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens KH domain containing 1 like (KHDC1L), mRNA.
ACCESSION   NM_001126063 XM_001716256 XM_001718926 XM_001725050
VERSION     NM_001126063.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 679)
  AUTHORS   Zhang,Q., Luo,S., Luo,Y., Huang,Y., Wang,Z. and Xie,X.
  TITLE     Upregulation of KHDC1L promotes the proliferation and inhibits
            apoptosis in head and neck squamous cell carcinoma
  JOURNAL   Epigenetics 18 (1), 2175168 (2023)
   PUBMED   36734243
  REMARK    GeneRIF: Upregulation of KHDC1L promotes the proliferation and
            inhibits apoptosis in head and neck squamous cell carcinoma.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL365232.24 and BC004267.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001126063.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189652.169560.1,
                                           SRR1803611.204169.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2142363
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000370388.4/ ENSP00000359415.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-44                AL365232.24        92342-92385         c
            45-679              BC004267.1         1-635
FEATURES             Location/Qualifiers
     source          1..679
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q13"
     gene            1..679
                     /gene="KHDC1L"
                     /note="KH domain containing 1 like"
                     /db_xref="GeneID:100129128"
                     /db_xref="HGNC:HGNC:37274"
     exon            1..200
                     /gene="KHDC1L"
                     /inference="alignment:Splign:2.1.0"
     CDS             89..475
                     /gene="KHDC1L"
                     /note="RP11-257K9.7; KH homology domain containing 1-like"
                     /codon_start=1
                     /product="putative KHDC1-like protein"
                     /protein_id="NP_001119535.1"
                     /db_xref="CCDS:CCDS47450.1"
                     /db_xref="GeneID:100129128"
                     /db_xref="HGNC:HGNC:37274"
                     /translation="MAVGTSALSKEPWWTLPENFHSPMVFHMEEDQEELIFGLDDTYL
                     RCIELHSHTLIQLERCFTATGQTRVTVVGPPMAKQWLLLMFHCVGSQDSKCHARGLKM
                     LERVRSQPLTNDDLVTSVSLPPYTGD"
     exon            201..383
                     /gene="KHDC1L"
                     /inference="alignment:Splign:2.1.0"
     exon            384..679
                     /gene="KHDC1L"
                     /inference="alignment:Splign:2.1.0"
     regulatory      653..658
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KHDC1L"
                     /note="hexamer: AATAAA"
     regulatory      658..663
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KHDC1L"
                     /note="hexamer: AATAAG"
     polyA_site      673
                     /gene="KHDC1L"
                     /note="major polyA site"
     polyA_site      679
                     /gene="KHDC1L"
                     /note="major polyA site"
ORIGIN      
        1 agagcctagg cccttcctcg cttttccaag tcttttgcca accagtttgt tagactttcc
       61 cctattctga atcaggtggg agcacagcat ggccgtggga acgagtgctc tcagcaagga
      121 gccgtggtgg accctgcccg aaaactttca ttctccaatg gtgttccaca tggaagagga
      181 ccaggaggag ctcatcttcg gacttgatga cacgtacctt cgctgcattg agctgcacag
      241 ccacaccctt attcagctgg agaggtgttt cacagctaca ggccagacac gtgtgactgt
      301 agtcggacca ccaatggcaa agcagtggct gctgctcatg ttccattgcg tggggagcca
      361 ggactccaag tgtcacgctc gaggtctgaa gatgctagag cgtgtccgaa gccagcccct
      421 gaccaatgat gacctggtca cctccgttag cctgccaccg tacaccggag actgatctcc
      481 cctgggaaga ggggatgaga ggagaagtct tggcttcgct tttggtgaga aagacatgaa
      541 aaacactgaa gaaagtttga atttgtggcc agacctgccc ctctcaggcc ttctaggcat
      601 gtgtctgagg gaagtctcct gagtgttaga agtgttattg gcaaagcaat ccaataaaat
      661 aagctaccta tgatgcaaa
//
