LOCUS       NM_030568               1146 bp    mRNA    linear   PRI 11-FEB-2024
DEFINITION  Homo sapiens KH domain containing 1 (KHDC1), transcript variant 2,
            mRNA.
ACCESSION   NM_030568
VERSION     NM_030568.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1146)
  AUTHORS   Pierre,A., Gautier,M., Callebaut,I., Bontoux,M., Jeanpierre,E.,
            Pontarotti,P. and Monget,P.
  TITLE     Atypical structure and phylogenomic evolution of the new eutherian
            oocyte- and embryo-expressed KHDC1/DPPA5/ECAT1/OOEP gene family
  JOURNAL   Genomics 90 (5), 583-594 (2007)
   PUBMED   17913455
REFERENCE   2  (bases 1 to 1146)
  AUTHORS   Oh,J.H., Yang,J.O., Hahn,Y., Kim,M.R., Byun,S.S., Jeon,Y.J.,
            Kim,J.M., Song,K.S., Noh,S.M., Kim,S., Yoo,H.S., Kim,Y.S. and
            Kim,N.S.
  TITLE     Transcriptome analysis of human gastric cancer
  JOURNAL   Mamm Genome 16 (12), 942-954 (2005)
   PUBMED   16341674
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA059235.1, DB473653.1, BC022080.2 and AL365232.24.
            
            On Jun 2, 2019 this sequence version replaced NM_030568.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DRR138520.458236.1, BC022080.2
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000257765.10/ ENSP00000257765.5
            RefSeq Select criteria :: based on manual assertion, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-12                DA059235.1         1-12
            13-141              DB473653.1         3-131
            142-648             BC022080.2         115-621
            649-653             AL365232.24        109022-109026       c
            654-1146            BC022080.2         624-1116
FEATURES             Location/Qualifiers
     source          1..1146
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q13"
     gene            1..1146
                     /gene="KHDC1"
                     /gene_synonym="bA257K9.4; C6orf147; C6orf148;
                     Em:AC019205.8; NDG1"
                     /note="KH domain containing 1"
                     /db_xref="GeneID:80759"
                     /db_xref="HGNC:HGNC:21366"
                     /db_xref="MIM:611688"
     exon            1..423
                     /gene="KHDC1"
                     /gene_synonym="bA257K9.4; C6orf147; C6orf148;
                     Em:AC019205.8; NDG1"
                     /inference="alignment:Splign:2.1.0"
     exon            424..548
                     /gene="KHDC1"
                     /gene_synonym="bA257K9.4; C6orf147; C6orf148;
                     Em:AC019205.8; NDG1"
                     /inference="alignment:Splign:2.1.0"
     CDS             437..931
                     /gene="KHDC1"
                     /gene_synonym="bA257K9.4; C6orf147; C6orf148;
                     Em:AC019205.8; NDG1"
                     /note="KH homology domain containing 1; Putative
                     KHDC1-like protein"
                     /codon_start=1
                     /product="KH homology domain-containing protein 1"
                     /protein_id="NP_085045.3"
                     /db_xref="CCDS:CCDS43480.1"
                     /db_xref="GeneID:80759"
                     /db_xref="HGNC:HGNC:21366"
                     /db_xref="MIM:611688"
                     /translation="MDMGTSALSKKPWWTLPQNFHAPMVFHMEEDQEELIFGHGDTYL
                     RCIEVHSHTLIQLESWFTATGQTRVTVVGPHRARQWLLHMFCCVGSQDSYHHARGLEM
                     LERVRSQPLTNDDLVTSISVPPYTGDLSLAPRISGTVCLSVPQPSPYQVIGCSGFHLS
                     SLYP"
     exon            549..731
                     /gene="KHDC1"
                     /gene_synonym="bA257K9.4; C6orf147; C6orf148;
                     Em:AC019205.8; NDG1"
                     /inference="alignment:Splign:2.1.0"
     exon            732..1146
                     /gene="KHDC1"
                     /gene_synonym="bA257K9.4; C6orf147; C6orf148;
                     Em:AC019205.8; NDG1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1125..1130
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KHDC1"
                     /gene_synonym="bA257K9.4; C6orf147; C6orf148;
                     Em:AC019205.8; NDG1"
                     /note="hexamer: AATAAG"
     polyA_site      1146
                     /gene="KHDC1"
                     /gene_synonym="bA257K9.4; C6orf147; C6orf148;
                     Em:AC019205.8; NDG1"
                     /note="major polyA site"
ORIGIN      
        1 acttccgctc gagcgcgcct cgcgcggccg cggcgcgagc cgggacccct ggaagggtcg
       61 ggtgcgcggc ccaggaggta ccgctgtctc ctcacaatcg gccaggcctg cagccgctgc
      121 cgccgctgcc gccgccgccg ccgccgccgc cgccgcccta ctcagggagt ggcccaggcc
      181 tgcggcgcgc caccctcacc tccttcattc ctaccgtcaa agcccagcct tggctacctg
      241 acccccctgt ggtctcgaac tcggttagtc cggtgaaggg acagagaagc ctgggttccc
      301 ggcggcatca ctgagatgct cagtcctgaa ttctgccctc cattaggatt atctgctttg
      361 tgggataatt tcctcattgg ttgagtcagt gagttgcgtg tctgcaagag agcatcctat
      421 ctggtcggag cagagcatgg acatgggaac gagtgctctc agcaagaagc cgtggtggac
      481 cctgcctcaa aactttcatg caccaatggt gtttcacatg gaagaggacc aggaggagct
      541 catcttcggg catggtgaca cataccttcg ctgcattgag gtgcacagcc acacccttat
      601 tcagctggag agttggttca cagctacagg ccagactcgt gtgactgtag tcggaccaca
      661 cagggcaagg cagtggctgc tgcacatgtt ttgttgtgtg gggagccagg actcctatca
      721 tcatgctcga ggcctggaga tgctggaacg tgtccgaagc cagcctctga ccaacgatga
      781 cctggtcacc tccattagtg tgccaccata cactggagac ctgtctttgg ctcccaggat
      841 aagtggaacc gtgtgtctta gcgttcctca gccttcccct taccaagtga ttggttgttc
      901 gggtttccat ttgagttcac tgtatccgta attaaggact gatctcccct gggaagtggg
      961 gatgagagga gaaatcttgg cttcactttt ggtgagaaag acatgataga cactgaggaa
     1021 agtttgaact tgtggccggg acctgtccct ctcaggtctt ctagacatgt ctgagggaag
     1081 tctcttgaat gtaagaaagt gttattggca aagcaatcca ataaaataag ctacctatga
     1141 tgcaaa
//
