LOCUS       XM_047429699            5054 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens lysine demethylase 2B (KDM2B), transcript
            variant X20, mRNA.
ACCESSION   XM_047429699
VERSION     XM_047429699.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000012.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5054
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
     gene            1..5054
                     /gene="KDM2B"
                     /gene_synonym="CXXC2; Fbl10; FBXL10; JHDM1B; PCCX2"
                     /note="lysine demethylase 2B; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 33
                     ESTs, 396 long SRA reads, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     4 samples with support for all annotated introns"
                     /db_xref="GeneID:84678"
                     /db_xref="HGNC:HGNC:13610"
                     /db_xref="MIM:609078"
     CDS             93..4034
                     /gene="KDM2B"
                     /gene_synonym="CXXC2; Fbl10; FBXL10; JHDM1B; PCCX2"
                     /codon_start=1
                     /product="lysine-specific demethylase 2B isoform X20"
                     /protein_id="XP_047285655.1"
                     /db_xref="GeneID:84678"
                     /db_xref="HGNC:HGNC:13610"
                     /db_xref="MIM:609078"
                     /translation="MKGNVFRSAADCKGSGLAVFPRPIDRQRYDENEDLSDVEEIVSV
                     RGFSLEEKLRSQLYQGDFVHAMEGKDFNYEYVQREALRVPLIFREKDGLGIKMPDPDF
                     TVRDVKLLVGSRRLVDVMDVNTQKGTEMSMSQFVRYYETPEAQRDKLYNVISLEFSHT
                     KLEHLVKRPTVVDLVDWVDNMWPQHLKEKQTEATNAIAEMKYPKVKKYCLMSVKGCFT
                     DFHIDFGGTSVWYHVFRGGKIFWLIPPTLHNLALYEEWVLSGKQSDIFLGDRVERCQR
                     IELKQGYTFFIPSGWIHAVYTPVDSLVFGGNILHSFNVPMQLRIYEIEDRTRVQPKFR
                     YPFYYEMCWYVLERYVYCVTQRSHLTQEYQRESMLIDAPRKPSIDGFSSDSWLEMEEE
                     ACDQQPQEEEEKDEEGEGRDRAPKPPTDGSTSPTSTPSEDQEALGKKPKAPALRFLKR
                     TLSNESEESVKSTTLAVDYPKTPTGSPATEVSAKWTHLTEFELKGLKALVEKLESLPE
                     NKKCVPEGIEDPQALLEGVKNVLKEHADDDPSLAITGVPVVTWPKKTPKNRAVGRPKG
                     KLGPASAVKLAANRTTAGARRRRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQS
                     CIMRQCIAPVLPHTAVCLVCGEAGKEDTVEEEEGKFNLMLMECSICNEIIHPGCLKIK
                     ESEGVVNDELPNCWECPKCNHAGKTGKQKRGPGFKYASNLPGSLLKEQKMNRDNKEGQ
                     EPAKRRSECEEAPRRRSDEHSKKVPPDGLLRRKSDDVHLRKKRKYEKPQELSGRKRAS
                     SLQTSPGSSSHLSPRPPLGSSLSPWWRSSLTYFQQQLKPGKEDKLFRKKRRSWKNAED
                     RMALANKPLRRFKQEPEDELPEAPPKTRESDHSRSSSPTAGPSTEGAEGPEEKKKVKM
                     RRKRRLPNKELSRELSKELNHEIQRTENSLANENQQPIKSEPESEGEEPKRPPGICER
                     PHRFSKGLNGTPRELRHQLGPSLRSPPRVISRPPPSVSPPKCIQMERHVIRPPPISPP
                     PDSLPLDDGAAHVMHREVWMAVFSYLSHQDLCVCMRVCRTWNRWCCDKRLWTRIDLNH
                     CKSITPLMLSGIIRRQPVSLDLSWTNISKKQLSWLINRLPGLRDLVLSGCSWIAVSAL
                     CSSSCPLLRTLDVQWVEGLKDAQMRDLLSPPTDNRPGQMDNRSKLRNIVELRLAGLDI
                     TDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTD
                     QCLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEMSSFQGRSCSTTRLGDE"
ORIGIN      
        1 agtgtgagcc ctggcagcgg cacatacgcg ctatgtgatc ctggggctgg tcgcctagta
       61 aaggagtcca cagaggcggg cagaatgaat gaatgaaagg caacgtcttc cggtcagctg
      121 cggactgcaa aggctctggt ctggctgtat ttcctcgccc gattgaccgc cagcgatacg
      181 acgagaacga ggacttgtcg gacgtggagg agatcgtcag cgtccgcggc ttcagcctgg
      241 aggagaagct tcgcagccag ctgtaccagg gggacttcgt gcacgccatg gagggcaaag
      301 atttcaacta tgagtacgta cagagagaag ctctcagggt tcccctgata tttcgagaaa
      361 aggatggact gggaattaag atgcctgacc ctgatttcac agtccgagac gtcaaactcc
      421 tagtggggag ccggcggctt gtggacgtga tggatgtgaa cacccagaag ggcacggaga
      481 tgagcatgtc ccagtttgtg cgttactacg agacgcccga ggcccagcgg gacaagctgt
      541 acaacgtcat cagcctagag ttcagccaca ccaagctgga gcacttggtc aagcgtccga
      601 ctgtggtaga cctggtggac tgggtggaca acatgtggcc ccagcatctg aaggagaagc
      661 agacagaagc cacgaacgcc attgcagaga tgaagtaccc gaaagtgaaa aagtactgtc
      721 tgatgagcgt gaaaggttgt ttcaccgact tccacatcga ctttggaggc acttccgttt
      781 ggtaccatgt tttccggggt gggaagattt tttggctgat tcctccaacg ctgcacaatt
      841 tggcgctgta cgaggagtgg gtgctgtcag gcaaacagag tgacatcttt ctgggagacc
      901 gtgtggaacg atgccaaaga attgagctga agcagggcta cacatttttc atcccttccg
      961 gttggatcca tgccgtctac acccctgtag actctttggt gttcggcgga aacatcctgc
     1021 acagctttaa cgtgcccatg cagctgcgga tctacgagat cgaggacagg acgcgggtgc
     1081 agcccaaatt ccgttacccc ttctactatg agatgtgctg gtatgtcctg gagagatacg
     1141 tgtactgtgt gacccagcgc tcccacctca ctcaggaata ccagagggag tcgatgctta
     1201 ttgatgcccc gaggaagccc agcatagacg gcttctcttc ggattcctgg ctggagatgg
     1261 aggaggaggc ctgtgatcag cagcctcagg aggaggagga gaaggacgag gagggcgagg
     1321 gcagggacag ggcacccaaa ccgcccaccg atggctccac ttcacccacc agcacgccct
     1381 ctgaggacca ggaggccctc gggaagaagc ccaaagcacc tgccctgcga ttcctcaaaa
     1441 ggactttgtc taatgagtcg gaggaaagtg tgaagtccac cacattggcc gtagactacc
     1501 ccaagacccc caccggctct cccgccacgg aggtctctgc caaatggacc catctcactg
     1561 agtttgaact gaagggcctg aaagctctgg tggagaaact ggaatccctc ccggagaaca
     1621 agaagtgtgt ccccgagggc atcgaggacc cccaggcact cctggagggt gtgaagaacg
     1681 tcctgaagga gcacgcagat gatgacccta gtctggccat cactggggtc cctgtggtga
     1741 cttggccaaa gaagactcca aagaaccggg ctgtgggtcg gcccaagggg aagctgggcc
     1801 cggcctccgc ggtgaagttg gccgccaacc ggacaacggc aggagctcgg cggcgccgga
     1861 cgcgatgccg caagtgcgag gcctgcctgc ggaccgagtg cggagagtgc cacttctgca
     1921 aggacatgaa gaagttcggg ggccccgggc gcatgaagca gagctgcatc atgcggcagt
     1981 gcatcgcgcc agtgctgccc cacaccgccg tgtgccttgt gtgtggcgag gcggggaagg
     2041 aagacacggt ggaagaggag gaaggcaagt ttaacctcat gctcatggag tgctccatct
     2101 gcaatgaaat catccaccct ggatgcctta agattaagga gtcagagggt gtggtcaacg
     2161 acgagcttcc aaactgctgg gagtgtccga agtgtaacca cgccggcaag accgggaaac
     2221 aaaagcgtgg ccctggcttt aagtacgcct ccaacctgcc cggctccctg ctcaaggagc
     2281 agaagatgaa ccgggacaac aaggaagggc aggaacctgc caagcggagg agtgagtgtg
     2341 aggaggcgcc ccggcgcagg tcggatgagc actcgaagaa ggtgccgccg gacggccttc
     2401 tgcgcagaaa gtctgacgac gtgcacctga ggaagaagcg gaaatacgag aagccccagg
     2461 agctgagtgg acgcaagcgg gcctcatcgc ttcaaacgtc ccccggttcc tcctctcacc
     2521 tctcgccgag gccccctcta ggcagcagcc tcagcccctg gtggagatcc agtctcactt
     2581 acttccagca gcagctcaaa cctggcaaag aagataagct tttcaggaaa aagcggcggt
     2641 cctggaagaa cgccgaggac cgcatggcgc tggccaacaa gcccctccgg cgcttcaagc
     2701 aggaacccga ggacgaactg cccgaggcgc cccccaagac cagggagagc gaccactccc
     2761 gctccagctc ccccaccgcg ggacccagca ccgaaggggc cgagggcccg gaggagaaga
     2821 agaaggtgaa gatgcgccgg aagcggcggc ttcccaacaa ggagctgagc agggagctga
     2881 gcaaggagct caaccacgag atccagagga cggagaacag cctggccaac gagaaccagc
     2941 agcccatcaa gtcggagcct gagagcgagg gcgaggagcc caagcggccc ccgggcatct
     3001 gcgagcgtcc ccaccgcttc agcaaggggc tcaacggcac cccccgggag ctgcggcacc
     3061 agctggggcc cagcctgcgc agcccgcccc gtgtcatctc ccggccccca ccctccgtgt
     3121 ccccgcccaa gtgtatccag atggagcgcc atgtgatccg gccacccccc atcagccccc
     3181 cgcctgactc gctacccctg gacgatgggg cagcccacgt catgcacagg gaggtgtgga
     3241 tggccgtctt cagctacctc agccaccaag acctgtgtgt gtgcatgcgg gtctgcagga
     3301 cctggaaccg ctggtgctgc gataagcggt tgtggacccg cattgacctg aaccactgca
     3361 agtctatcac acccctgatg ctgagtggca tcatccggcg acagcccgtc tccctcgacc
     3421 tcagctggac caatatctcc aagaagcagc tgagctggct catcaaccgg ctgcctgggc
     3481 tccgggactt ggtgctgtca ggctgctcat ggatcgcggt ctcggccctt tgcagctcca
     3541 gttgtccgct gctccggacc ctggatgtcc agtgggtgga gggactaaag gatgcccaga
     3601 tgcgggatct cctgtccccg cccacagaca acaggccagg tcagatggac aatcggagca
     3661 agctccggaa catcgtggag ctgcgcctgg caggcctgga catcacagat gcctccctgc
     3721 ggctcatcat ccgccacatg cccctgctct ccaagctcca cctcagttac tgtaaccacg
     3781 tcaccgacca gtctatcaac ctgctcactg ctgttggcac caccacccga gactccttaa
     3841 ccgagatcaa cctgtctgac tgcaataagg tcactgatca gtgcctgtcc ttcttcaaac
     3901 gctgtggaaa catctgtcat attgacctga ggtactgcaa gcaagtcacc aaggaaggct
     3961 gtgagcagtt catagccgag atgtcttctt tccaagggag aagctgttca accacccgtt
     4021 tgggggatga gtgagccgac actttccttt ggtctttctg aatcgtaact gcactgcttt
     4081 ctggaccatt tctaaggcgg cctttacaag aagacattcc tgtcggagag gagggtggac
     4141 ttcggagaaa ttctcatact gaagcatgag cttaggagtt tctgttagtg gtagtggtgt
     4201 tttggacact tcattccttg caacaccgag gttttgggtg ttgacataaa gtggaccaca
     4261 caccacatct gctgccgtct tgacactttt ttttgtttgg ttggttttgt tacatcttac
     4321 attatgcaga actatttttg tacaaattgt ttaaaagtta tttatgcaag gtttgaatgc
     4381 ataccagtgt ttttattgtt ttgagattgc caattttcct gatttcctta aggtaggaga
     4441 gaatttaacg tgtacttcat cgacacaacc catctacaaa tgtgcccaga tctaacaaag
     4501 taggctaaga ccttccactt aaaagcatgt ttaactggaa gttgagagtc tgctttgtac
     4561 ctcaagagtt acatgagcat gttgtggata aatgtaaatt atagtcaaag taagatactc
     4621 tgccaagttt cctctgtaga gaattcactt ttctcaaatt ttaaaatttc gacttcagcc
     4681 tttgcactca ggaggttctg ctccagcatg agctcttgta cttacataga tctaatttat
     4741 acagtgagtc aagacgtaga ataaatgctc ccacatagcc tttcttttgc ttttgcttct
     4801 ctcctctgaa gtgtgagttg agttctcatt taggtttgta acatggctat ttcctagttg
     4861 taaagttctg catttataag tgccattgtt gtaaggtggt gtttcctaga ccttccctga
     4921 tgcgatttta cctttgttga atttgtataa acaattgtac aaaaaaaacc actcttgaac
     4981 tttgagggtt tctgttctag gagtggacta gaagtttaag cccagagtca gtaaacactg
     5041 ttttgaagtc caaa
//
