LOCUS       XM_017010443            4524 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens lysine demethylase 1B (KDM1B), transcript
            variant X7, mRNA.
ACCESSION   XM_017010443
VERSION     XM_017010443.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000006.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017010443.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4524
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
     gene            1..4524
                     /gene="KDM1B"
                     /gene_synonym="AOF1; C6orf193; LSD2"
                     /note="lysine demethylase 1B; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 2
                     mRNAs, 17 ESTs, 1072 long SRA reads, 2 Proteins, and 99%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 6 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:221656"
                     /db_xref="HGNC:HGNC:21577"
                     /db_xref="MIM:613081"
     CDS             164..2662
                     /gene="KDM1B"
                     /gene_synonym="AOF1; C6orf193; LSD2"
                     /codon_start=1
                     /product="lysine-specific histone demethylase 2 isoform
                     X1"
                     /protein_id="XP_016865932.1"
                     /db_xref="GeneID:221656"
                     /db_xref="HGNC:HGNC:21577"
                     /db_xref="MIM:613081"
                     /translation="MATPRGRTKKKASFDHSPDSLPLRSSGRQAKKKATETTDEDEDG
                     GSEKKYRKCEKAGCTATCPVCFASASERCAKNGYTSRWYHLSCGEHFCNECFDHYYRS
                     HKDGYDKYTTWKKIWTSNGKTEPSPKAFMADQQLPYWVQCTKPECRKWRQLTKEIQLT
                     PQIAKTYRCGMKPNTAIKRRGFAVLPRPETSDHCSLPEDLRVLEVSNHWWYSMLILPP
                     LLKDSVAAPLLSAYYPDCVGMSPSCTSTNRAAATGNASPGKLEHSKAALSVHVPGMNR
                     YFQPFYQPNECGKALCVRPDVMELDELYEFPEYSRDPTMYLALRNLILALWYTNCKEA
                     LTPQKCIPHIIVRGLVRIRCVQEVERILYFMTRKGLINTGVLSVGADQYLLPKDYHNK
                     SVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNG
                     CINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRK
                     DKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSAR
                     SWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPQVQCIDYSGDEVQVTTTD
                     GTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWD
                     SKVQGADFFGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQVL
                     QQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQG
                     TVFFAGEATNRHFPQTVTGAYLSGVREASKIAAF"
ORIGIN      
        1 gtgacagggg cggaagcggc ggcggcggcg gcggccgaga agaggctggg gctcgcggcg
       61 cggctgcagc cgtcctgtgc gcgcggcgcg cggctccgga gaggcgcccg cagtccaggg
      121 cggcgcgcac cgcctcgctg gcgctcagag attatttaat gtaatggcaa ctccacgggg
      181 gaggacaaag aaaaaagcat cttttgatca ttctccggat agccttcctt tgaggagctc
      241 cggtaggcag gcgaagaaga aagcaacaga gacaacagat gaggatgaag atggtggctc
      301 agagaagaag tacaggaaat gtgaaaaggc aggctgtacg gcaacatgtc ctgtgtgctt
      361 tgcaagtgct tctgaaagat gtgccaaaaa tggctacacc tcccgatggt atcatctctc
      421 ctgtggggaa catttctgta atgaatgctt tgaccattac tacagaagcc ataaggatgg
      481 atatgacaaa tatactacat ggaaaaaaat atggactagc aatggcaaaa ccgaacctag
      541 tcccaaagct ttcatggcag accagcaact cccctactgg gttcagtgta caaaacctga
      601 gtgtagaaaa tggaggcagc ttaccaagga aatccagctt actccacaga tagccaagac
      661 ttatcgatgc ggtatgaaac caaatactgc tattaagaga cggggttttg ctgtcttgcc
      721 caggcctgag acctcagatc attgttccct cccagaggat ctaagagtat tggaagtttc
      781 caaccattgg tggtactcta tgctcatcct acctcctttg ctgaaagaca gtgtggcagc
      841 gcccctgctg tctgcctact accctgactg tgttggcatg agcccctcct gcaccagcac
      901 aaaccgcgcc gctgccactg gcaatgccag ccctgggaag ctggagcact ccaaggctgc
      961 cctctccgtg cacgttccag gcatgaaccg atacttccag cctttctacc agcccaatga
     1021 gtgtggcaaa gccctctgtg tgaggccgga tgtgatggaa ctggatgagc tctatgagtt
     1081 tccagagtat tcccgagacc ccaccatgta cctggctttg agaaacctca tcctcgcact
     1141 gtggtatact aactgcaaag aagctcttac tcctcagaaa tgtattcctc acatcatcgt
     1201 ccggggtctc gtgcgtattc gatgcgttca ggaagtggag agaatactgt attttatgac
     1261 cagaaaaggt ctcatcaaca ctggagttct cagcgtggga gccgaccagt atcttctccc
     1321 taaggactac cacaataaat cagtcatcat tatcggggct ggtccagcag gattagcagc
     1381 tgctaggcaa ctgcataact ttggaattaa ggtgactgtc ctggaagcca aagacagaat
     1441 tggaggccga gtctgggatg ataaatcttt taaaggcgtc acagtgggaa gaggagctca
     1501 gattgtcaat gggtgtatta acaacccagt agcattaatg tgtgaacaac ttggcatcag
     1561 catgcataaa tttggagaaa gatgtgactt aattcaggaa ggtggaagaa taactgaccc
     1621 cactattgac aagcgcatgg attttcattt taatgctctc ttggatgttg tctctgagtg
     1681 gagaaaggat aagactcagc tccaagatgt ccctttagga gaaaagatag aagaaatcta
     1741 caaggcattt attaaggaat ctggtatcca attcagtgag ctggagggac aggtgcttca
     1801 gttccatctc agtaacctgg agtacgcctg tggcagcaac cttcaccagg tatctgctcg
     1861 ctcgtgggac cacaatgaat tctttgccca gtttgctggt gaccacactc tgctaactcc
     1921 cgggtactcg gtgataattg aaaaactggc agaagggctt gacattcaac tcaaatctcc
     1981 acaggtgcag tgtattgatt attctggaga tgaagtgcag gttaccacta cagatggcac
     2041 agggtattct gcacaaaagg tattagtcac tgtaccactg gctttactac agaaaggtgc
     2101 cattcagttt aatccaccgt tgtcagagaa gaagatgaag gctatcaaca gcttaggcgc
     2161 aggcatcatt gaaaagattg ccttgcaatt tccgtataga ttttgggaca gtaaagtaca
     2221 aggggctgac ttttttggtc acgttcctcc cagtgccagc aagcgagggc tttttgccgt
     2281 gttctatgac atggatcccc agaagaagca cagcgtgctg atgtctgtga ttgccgggga
     2341 ggctgtcgca tccgtgagga ccctggatga caaacaggtg ctgcagcagt gcatggccac
     2401 gctccgggag ctgttcaagg agcaggaggt cccagatccc acaaagtatt ttgtcactcg
     2461 gtggagcaca gacccatgga tccagatggc atacagtttt gtgaagacag gtggaagtgg
     2521 ggaggcctac gatatcattg ctgaagacat tcaaggaacc gtctttttcg ctggtgaggc
     2581 aacaaacagg catttcccac aaactgttac aggggcatat ttgagtggcg ttcgagaagc
     2641 aagcaagatt gcagcatttt aagaattcgg tggacccagc tttcttctgt accccagatg
     2701 gggaaatttg aatcacatgt taaacctcag ttttataaga gggggaaaaa accgtctcta
     2761 catagtaaaa ctgaaatgtt tctaaggcga tatgataatg caaacctatt tcatcactct
     2821 aaaagcactg acctcaaaaa accttataag cacttagatt taattgcatt ttccataggt
     2881 tcaactactg ctgaaagtct ggatttcaga ataaagcaga atgtaagttt cagttgaggc
     2941 catggatttg attgttccat ggctggaagt tccctttaga tttcacattt tatatggctg
     3001 atcaattttc atacattgag aaaccaagtc aatcaagcag gaatcattta aaaaccagat
     3061 aaagccatgt ttttcttctg tgacaattta tcagtatctt taccaatgag ccttaatttt
     3121 tatataggtc caatattgag cttttactta aaatttagat agaacttttt tttggataca
     3181 gcacaaactc cagttgacag taaaatgaag cttctaggta ttttgtattg tacatatttc
     3241 ctcctactgg gtgttcaaaa gaaatttaaa ttcaagtacc ttttgtgata aaatgtttta
     3301 gatttgtgca cccattggca aaacaggaaa gtttccagat aggtattgta tcattgagaa
     3361 tgcagcacag atagtgtggg cttcacacta tagacacaga atatagcttt ttcttaaagc
     3421 caaatttggg tgataggaca ctttaaatat ccttaatttt ggcaaccact agcaaaaaaa
     3481 cttgtcagaa taatttaacc aagcccctct ccacttcttt tatttaaaag cactgattca
     3541 attgctagga atatttttgc agatttttct ttacagtatt ccataggcag gtccactgga
     3601 aaactgcaga aaaatgtgag ctctcctggt aaatagtata cattttataa gctatatttt
     3661 aaaggcctaa gaacatggca agtatttact tttatctttt ttttaaaaac actcatgaca
     3721 gaaaacagtt taataatatc tcattctaaa ataaaacact ggttgcaggg tcttcaggat
     3781 gcctattttg ccaagaaact tcagtataca ggttagaaat atgcttttgt ttttgaacaa
     3841 taatatactg gtttgcttta aagaagggac taaatatgac tttaaagaga cttcaaaata
     3901 ttgagtattt taaaaattta aaagtaggtc agtttataac gagtaaatac ctaacacacc
     3961 aagaatgtgc agtgaacctc aggcatttaa gacacctccc ccaccgcccg ccccccgccc
     4021 cccccaatca aagtgtggtc ccaaaacaag ccaacagctg tatatctcaa aagttaaccc
     4081 aagacaactc tgatatttag gttatttgtt gagactcatt ggtactgact ggcaagtatt
     4141 ctgctttaaa gtatcatgta ttaaaatgtt tagacagcat gtgttttaaa gtgataaatg
     4201 caaaatgtta agtttgaaat ggttaacagt aaattattat gttagtttcc aggcacttga
     4261 actgtgctac aagtagggga aaacctactt taaagtatgg taaatgtgtg ttttaaactt
     4321 cctatcaagt gacatacttc atttgatttt ttgtttaaga agccatggta cttttttctt
     4381 gagttacttt ggatatgttt tttcaatgcc atctgaagat tttgtaattg agtagcagta
     4441 aatatacaga tttacaatgt tttaactaca gttcatgaat agctggttgt gtaaaactaa
     4501 taaaaaacta gactttcaca tgta
//
