LOCUS       XM_047429638            4440 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens potassium channel tetramerization domain
            containing 10 (KCTD10), transcript variant X2, mRNA.
ACCESSION   XM_047429638
VERSION     XM_047429638.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000012.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4440
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
     gene            1..4440
                     /gene="KCTD10"
                     /gene_synonym="BTBD28; hBACURD3; MSTP028; ULRO61"
                     /note="potassium channel tetramerization domain containing
                     10; Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 35 ESTs, 680 long SRA reads, and 93%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 40 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:83892"
                     /db_xref="HGNC:HGNC:23236"
                     /db_xref="MIM:613421"
     CDS             39..929
                     /gene="KCTD10"
                     /gene_synonym="BTBD28; hBACURD3; MSTP028; ULRO61"
                     /codon_start=1
                     /product="BTB/POZ domain-containing adapter for
                     CUL3-mediated RhoA degradation protein 3 isoform X2"
                     /protein_id="XP_047285594.1"
                     /db_xref="GeneID:83892"
                     /db_xref="HGNC:HGNC:23236"
                     /db_xref="MIM:613421"
                     /translation="MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYY
                     TTMQTLTKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESR
                     REIEELLAEAKYYLVQGLVEECQAALQNKDTYEPFCKVPVITSSKEEQKLIATSNKPA
                     VKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYG
                     QGRKIAEVCCTSIVYATEKKQTKEHEDRKSNQILPILLRPQLFSSEKKVPSLRVLTPA
                     VSGCCHRNAQVWVQENKEKD"
     polyA_site      4440
                     /gene="KCTD10"
                     /gene_synonym="BTBD28; hBACURD3; MSTP028; ULRO61"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 agtccgggtt tggagactcc tgcgtcctcc gacttttcat ggaagagatg tcaggagaaa
       61 gtgtggtgag ctcagcggtg ccagcggctg ctacccgcac cacttccttc aagggcacga
      121 gccccagctc caaatacgtg aagctgaatg tgggtggagc cctctactat accaccatgc
      181 agacgctgac caagcaggac accatgctga aggccatgtt cagcgggcgc atggaagtgc
      241 tcaccgacag tgaaggctgg atcctcattg accgctgtgg gaagcacttt ggtacgatac
      301 tcaactacct tcgagacggg gcggtgcctt tacccgagag ccgccgggag atcgaggagc
      361 tgctagcaga agccaagtac tacctagtcc aaggcctggt ggaagagtgc caggcggccc
      421 tacaaaacaa agatacttat gagcctttct gcaaggtccc tgtgatcacc tcatccaagg
      481 aagaacaaaa acttatagcg acttcaaata agccagccgt gaagttgctc tacaacagaa
      541 gtaacaacaa atactcatat accagcaatt ctgacgacaa tatgttgaaa aacattgaac
      601 tgtttgataa gctgtctctg cgctttaacg gaagggtcct gttcataaag gatgttattg
      661 gggatgaaat ctgctgctgg tccttttatg gtcagggccg gaagattgct gaagtctgtt
      721 gtacctccat cgtctatgcc actgagaaga aacagaccaa ggagcatgaa gatagaaaaa
      781 gcaaccagat tctcccaatc ctgctgagac cacagctctt ctcatcagaa aagaaggttc
      841 cttccctcag agttttgact cctgcagtct ctggttgctg ccacaggaat gctcaggtct
      901 gggtgcaaga aaataaagaa aaggactgag catggtggct cacacctgta atcccgcact
      961 ttgggaggcc aaagcagaag gattgcttga gtccaggagt ttaagaccag cctgggcaac
     1021 atagcaacac ccctgtctct accaaaaatt ttttaaaaaa tagctgggca tggtggtgtg
     1081 tgcctgtagt ctaaactact tgggaggctg aggtgggaga atcatttaag cccagtagtt
     1141 caagaccagc ctgggcaaca tagcaacaca ctcatctcta caaaaagtta gttgggcatg
     1201 gtgatgcatg cctatagtct caactacttg gggaggctga ggtgggagaa tcatttgagc
     1261 ctaggcgttc aaggctgcag tgagctatga ttgtgccact gcactccagc ctgggtgaca
     1321 gagcaacact ccctctcaaa acaaaaaaga gaaaagaaag aggcccttgg actcccgtcc
     1381 tggctctgcc cctaaccagc ttcacaaaca caagaacacg ccactcctga acctggtctg
     1441 tgaatcaaga aacagttggg atcagaccat gtggtctcta aatccccttg ctccttatta
     1501 agctctaaaa atgagaagtc ttaaaatttt aaagcttaat tagccagatc ccatatcttt
     1561 taaaaaaaaa ggaaagaaaa ccaggatttc ctcccagcct ctctgcctgt tagactctgt
     1621 tggcctccct ggccactaga gaccttctgg aggtcttctg tcctggtgcc atttcagggt
     1681 ttcaggctgc atcagtgctg gcagcagcaa acagtaaact cactgttggg cattactcca
     1741 aattctgttg tttcccccat ctgcctgcca tgatttactt ctgagtccac agttagctgc
     1801 tgtgtgcatc ccattctggc tttgtagtgt cagtgaggaa gacggggtag agtgtgcctg
     1861 ctccattttt cccagaacct ccgaattcca ccctgaaagt ggagtctagt ctgatcaaat
     1921 gtgtgggacc tgcttatgtg gccctcttcc tgttcatcac accttaaccc tgaagggcaa
     1981 tgagcaaaca caatgatttg ccaaacagca gaagggctca tgcccatttc gtgggagtcc
     2041 ccagctggac cctgtacaaa aaactgcttt agagactgct ttaaggtgtg gaaggacttc
     2101 tgtgcaaggt tgcagctctg ttaggagaag catattagca ctgacctaaa tggccatcca
     2161 agtatggtta attgcattgt cgtatttata attccttgat acagaatgat ctctaggtta
     2221 agttaggcac aagaggaaga catgtacaac tctgtgtggt gggccacctt gtgtgttttt
     2281 tgaagtgtgt gaataaatat gtgtattaca catatttaca tgcacagaat ctttgagagg
     2341 gtaaaatgat gagaaactgt acctttaaga agggaaacta ggggcaggga gacctgtttc
     2401 tctgcatccc cttgattttc tgtgcattta gcaccacatg taagtgttgc cattgaaaat
     2461 atcagtttat ttaaaaataa tactggtggc cttcagcaga atcccagggg cctgatttag
     2521 cctggcggcc ctgcttaaag tccaggtgtt ggcagagggg gtgggccata acttacctgc
     2581 cctgtatact gtgggaacac aggtggagtt tcccgaagcc cggatttatg aggagaccct
     2641 gaacattttg ctgtatgagg cccaggatgg ccggggacct gacaatgcgc tcctggaggc
     2701 cacaggcggg gcggcggggc gctcccacca cctggacgag gacgaggagc gggagcggat
     2761 cgagcgcgtg cggaggatcc acatcaagcg ccctgatgac cgggcccacc tccaccagtg
     2821 agcaggcaag agaccgagcc gccctcctct caccgccccc actccctgcc gtgctacacc
     2881 cagatcctgt gcaggctgcc gggccccttc tgcttccctt ggagcctgga gatacttttg
     2941 taacaagcca gatgattatt ttggtattgc ttgacaaggc aaattgattg tcttgaccca
     3001 ggcgtatgac ccctgtcgtt gaacaagctg tgtctaagat ctctactttt catgagaatc
     3061 tgagactctt tggagccagg ctttctcggt tctcagagga aaagtatgaa tgagtgtgaa
     3121 gtgtatgtga gaacttttgt ttgcaatatt tatttttgtg ggtgtcgact tcctatgtgg
     3181 gctttttggg tgacactccc ttaagggttc agtttgacaa ttctgagagt tgtcctgcag
     3241 ttggaggcca ccagaggtat ctgagctccc tgcttcctat ttcataatcc tccagcccca
     3301 gcaggtccac tcctggttcc tgtgtgtttg gcccgggcac aatccccact gctttgctag
     3361 acgtgctttc tgccatgtgg ctttgggcct agagcttgtt gataattgca gcttgtggca
     3421 gtggaaatat ggctgaatga gcgtctaaat cgttgagacc agtgcaactt tgggtgcaag
     3481 gctttgttta gggatcaagc cttttgccac cttgggctgg tctttggcct ggtgctcact
     3541 gggaccccat atgtctgcgt aggagcagaa ctttccatgg cagtaagtgt ccagctctgt
     3601 ttctggttct ttccccaact ccagccccgt ccagttgttc tcctgattga cccgactcca
     3661 ctccaggaag gccatctgac cctgtgacag gcatagctca taaactaccc ctccctggga
     3721 tcccgctcct cttcagcctc cttccccatg aagctgggct aactttctaa gtcattttgc
     3781 ttagaaattc agtgtggccc ataccctttg tcctcccagc ctggcatcca ggcagggaca
     3841 ccctcacacc accagcccca gggagcttcc ctgctataaa cacagacccc cttgtctttg
     3901 cctctgattt ttacacagtg tagagtggcc agcagtgaac aggttgagga tgtgcgggta
     3961 gatagataac tttgggtctg gtttgtgtct gtgttcatgt ttgtttaagg gatatgtgtg
     4021 actgtgggtg gggacgtgtg cttgtggggc acaggtggcg gcccctgctg gagcccggct
     4081 gggcgcagcg cctatgtagg acgggtgttc tcagtgacct acctcccagg ctcctctgca
     4141 cctgcaaagg aacaggagtg agtcgtgact gacaggggtg gttgagacta gactaggtag
     4201 agtagttacc aggagatgtg aatgtgcgtc aggtgatgga tgggtttgtc aagggaatcg
     4261 ttaccgtttt ataccaaagg tattaacatg ggcagccttt gacacatgta ttccaaaaac
     4321 gagtttatat tttcaaacgg tttttacagc ttagactttg tacttactgc cctgcctgtg
     4381 acagttgtat gccttcattt tgtatccaac agcaaagtct acaataaaac tttaaaacaa
//
