LOCUS       XM_011518880            7033 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens potassium sodium-activated channel
            subfamily T member 1 (KCNT1), transcript variant X4, mRNA.
ACCESSION   XM_011518880
VERSION     XM_011518880.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000009.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011518880.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 7% of CDS bases
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..7033
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
     gene            1..7033
                     /gene="KCNT1"
                     /gene_synonym="bA100C15.2; DEE14; EIEE14; ENFL5; KCa4.1;
                     SLACK; Slo2.2"
                     /note="potassium sodium-activated channel subfamily T
                     member 1; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 2 mRNAs, 13 ESTs, 26 long SRA
                     reads, 3 Proteins, and 95% coverage of the annotated
                     genomic feature by RNAseq alignments, including 2 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:57582"
                     /db_xref="HGNC:HGNC:18865"
                     /db_xref="MIM:608167"
     CDS             21..3692
                     /gene="KCNT1"
                     /gene_synonym="bA100C15.2; DEE14; EIEE14; ENFL5; KCa4.1;
                     SLACK; Slo2.2"
                     /codon_start=1
                     /product="potassium channel subfamily T member 1 isoform
                     X4"
                     /protein_id="XP_011517182.1"
                     /db_xref="GeneID:57582"
                     /db_xref="HGNC:HGNC:18865"
                     /db_xref="MIM:608167"
                     /translation="MARAKLPRSPSEGKAGPGGAPAGAAAPEEPHGLSPLLPARGGGS
                     VGSDVGQRVQVEFYVNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLTCLLYIVRVL
                     LDDPALGIGCWGCPKQNYSFNDSSSEINWAPILWVERKMTLWAIQVIVAIISFLETML
                     LIYLSYKGNIWEQIFRVSFVLEMINTLPFIITIFWPPLRNLFIPVFLNCWLAKHALEN
                     MINDFHRAILRTQSAMFNQVLILFCTLLCLVFTGTCGIQHLERAGENLSLLTSFYFCI
                     VTFSTVGYGDVTPKIWPSQLLVVIMICVALVVLPLQFEELVYLWMERQKSGGNYSRHR
                     AQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDVQVRRVLQIPLW
                     SQRVIYLQGSALKDQDLMRAKMDNGEACFILSSRNEVDRTAADHQTILRAWAVKDFAP
                     NCPLYVQILKPENKFHVKFADHVVCEEECKYAMLALNCICPATSTLITLLVHTSRGQE
                     GQESPEQWQRMYGRCSGNEVYHIRMGDSKFFREYEGKSFTYAAFHAHKKYGVCLIGLK
                     REDNKSILLNPGPRHILAASDTCFYINITKEENSAFIFKQEEKRKKRAFSGQGLHEGP
                     ARLPVHSIIASMGTVAMDLQGTEHRPTQSGGGGGGSKLALPTENGSGSRRPSIAPVLE
                     LADSSALLPCDLLSDQSEDEVTPSDDEGLSVVEYVKGYPPNSPYIGSSPTLCHLLPVK
                     APFCCLRLDKGCKHNSYEDAKAYGFKNKLIIVSAETAGNGLYNFIVPLRAYYRSRKEL
                     NPIVLLLDNKPDHHFLEAICCFPMVYYMEGSVDNLDSLLQCGIIYADNLVVVDKESTM
                     SAEEDYMADAKTIVNVQTMFRLFPSLSITTELTHPSNMRFMQFRAKDSYSLALSKLEK
                     RERENGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMITITRLLLGLDTTPGSG
                     YLCAMKITEGDLWIRTYGRLFQKLCSSSAEIPIGIYRTESHVFSTSEPHDLRAQSQIS
                     VNVEDCEDTREVKGPWGSRAGTGGSSQGRHTGGGDPAEHPLLRRKSLQWARRLSRKAP
                     KQAGRAAAAEWISQQRLSLYRRSERQELSELVKNRMKHLGLPTTGYEDVANLTASDVM
                     NRVNLGYLQDEMNDHQNTLSYVLINPPPDTRLEPSDIVYLIRSDPLAHVASSSQSRKS
                     SCSHKLSSCNPETRDETQL"
ORIGIN      
        1 gcgccgagcg ctcccgcagg atggcgcggg ccaagctgcc gcgctcgccg tccgagggca
       61 aggcgggccc ggggggcgcc ccagccggcg ccgcagcccc cgaggagcct cacgggctca
      121 gcccgctgct gccggcccgc ggcgggggct ccgtgggcag cgacgtgggc cagagggtcc
      181 aggtggagtt ctacgtcaac gagaacacct tcaaggagcg gctcaagctg ttcttcatca
      241 aaaaccaaag atcgagcctg aggatccggc tgttcaactt ctccctgaag ctgctcacct
      301 gcctgctcta cattgtgcgc gtcctgctcg atgacccggc cctgggcatc ggatgctggg
      361 gctgcccaaa gcagaactac tccttcaatg actcgtcctc cgagatcaac tgggctccta
      421 ttctgtgggt ggagagaaag atgacactgt gggcgatcca ggtcatcgtg gccataataa
      481 gcttcctgga gacgatgctt ctcatctacc tcagctacaa aggcaacatc tgggagcaga
      541 tcttccgcgt gtccttcgtc ctggagatga tcaacactct gcccttcatc atcacgatct
      601 tctggccgcc gctgcggaac ctgttcatcc ccgtctttct gaactgctgg ctggccaagc
      661 acgcgctgga aaacatgatt aatgacttcc accgtgccat cctgcggaca cagtcagcca
      721 tgttcaacca ggtcctcatc ctcttctgca ccctgctgtg cctcgttttc acggggacct
      781 gcggcatcca gcacctggag cgggcgggcg agaacctgtc cctcctgacc tccttctact
      841 tctgcatcgt caccttctcc accgtgggct acggtgacgt cacgcccaag atctggccat
      901 cgcagctgct ggtggtcatc atgatctgcg tggccctcgt ggtgctccca ctgcagttcg
      961 aggagctcgt ctacctctgg atggagcggc agaagtcagg gggcaactac agccgccacc
     1021 gtgcgcagac ggagaagcac gtggtcctgt gtgtcagctc cctcaagatc gaccttctca
     1081 tggacttcct gaacgagttc tacgcccacc cccggctcca ggactattac gtggtcatcc
     1141 tgtgccccac ggagatggat gtccaggtgc gcagagtcct gcagatccct ctgtggtccc
     1201 agcgggtcat ctacctccag ggctctgcac tcaaagacca ggacctcatg cgagccaaga
     1261 tggacaatgg ggaggcctgc ttcatcctca gcagcaggaa cgaggtggac cgcacggctg
     1321 cagaccacca gaccatcctg cgcgcctggg ccgtgaagga cttcgccccc aactgccccc
     1381 tctacgtcca gatcctcaaa cctgaaaaca agtttcacgt caagtttgct gaccacgtgg
     1441 tgtgtgagga ggagtgcaag tacgccatgc tggcgctgaa ctgcatctgc ccggcgacct
     1501 ccaccctcat caccctgctg gtgcacacgt cccgcggcca ggagggacag gagtctccgg
     1561 agcagtggca gcgcatgtat gggcgctgct ccggcaacga ggtgtaccac atccgcatgg
     1621 gtgacagcaa gttcttccgc gagtacgagg gcaagagctt cacctacgcg gccttccacg
     1681 cccacaagaa gtatggcgtg tgcctcatcg ggctgaagcg ggaggacaac aagagcatcc
     1741 tgctgaaccc ggggccccgg cacatcctgg ccgcctctga cacctgcttc tacatcaaca
     1801 tcaccaagga ggagaactcg gccttcatct tcaagcagga ggagaagcgg aagaagaggg
     1861 ccttctcggg gcaggggctg cacgagggtc cggcccgcct gcccgtgcac agcatcatcg
     1921 cctccatggg gacagtggcc atggacctgc agggcacaga gcaccggcct acgcagagcg
     1981 gcggtggggg cgggggcagc aagctggcac tgcccacgga gaacggctcg ggcagccggc
     2041 ggcccagcat cgcgcccgtc ctggaactgg ccgacagctc agccctgctg ccctgcgacc
     2101 tgctgagcga ccagtcggag gatgaggtga cgccgtcgga cgacgagggg ctctccgtgg
     2161 tagagtatgt gaagggctac cctcccaact cgccctacat cggcagctcc ccaaccctgt
     2221 gccacctcct gcctgtgaaa gcccccttct gctgcctgcg gctggacaag ggctgcaagc
     2281 acaacagcta tgaagacgcc aaggcctacg ggttcaagaa caagctgatc atcgtctcgg
     2341 cagagacggc cggcaatggg ctgtacaact tcatcgtgcc actgcgggcc tactacagat
     2401 cccgcaagga gctgaacccc atcgtgctgc tgctggacaa caagcccgac caccacttcc
     2461 tggaagccat ctgctgcttc cccatggtct actacatgga gggctctgtg gacaacctgg
     2521 acagcctgct gcagtgtggc atcatctatg cggacaacct ggtggtggtg gacaaggaga
     2581 gcaccatgag cgccgaggag gactacatgg cggacgccaa gaccatcgtc aacgtgcaga
     2641 ccatgttccg gctcttcccc agcctcagca tcaccacgga gctcacccac ccttccaaca
     2701 tgcgcttcat gcagttccgc gccaaggaca gctactctct ggctctttcc aaactagaaa
     2761 agagggagcg agagaatggc tccaacctgg ccttcatgtt ccgcctgccg ttcgccgccg
     2821 gccgcgtctt cagcatcagc atgttggaca cactgctcta ccagtccttc gtgaaggact
     2881 acatgatcac catcacccgg ctgctgctgg gcctggacac cacgccgggc tcggggtacc
     2941 tctgtgccat gaaaatcacc gagggcgacc tgtggatccg cacgtacggc cgcctcttcc
     3001 agaagctctg ctcctccagc gccgagatcc ccattggcat ctaccggaca gagagccacg
     3061 tcttctccac ctcggagccc cacgacctca gagcccagtc ccagatctcg gtgaacgtgg
     3121 aggactgtga ggacacacgg gaagtgaagg ggccctgggg ctcccgcgct ggcaccggag
     3181 gcagctccca gggccgccac acgggcggcg gtgaccccgc agagcaccca ctgctacggc
     3241 gcaagagcct gcagtgggcc cggaggctga gccgcaaggc gcccaagcag gcaggccggg
     3301 cggcggccgc ggagtggatc agccagcagc gcctcagcct gtaccggcgc tctgagcgcc
     3361 aggagctctc cgagctggtg aagaaccgca tgaagcacct ggggctgccc accaccggct
     3421 acgaggacgt agcaaattta acagccagtg atgtcatgaa tcgggtaaac ctgggatatt
     3481 tgcaagacga gatgaacgac caccagaaca ccctctccta cgtcctcatc aaccctccgc
     3541 ccgacacgag gctggagccc agtgacattg tctatctcat ccgctccgac cccctggctc
     3601 acgtggccag cagctcccag agccggaaga gcagctgcag ccacaagctg tcgtcctgca
     3661 accccgagac tcgcgacgag acacagctct gagccagccc tgcacggagc tcaggccacc
     3721 aagcccgggg tcctcaggaa ggacgtggag gagcgtgtga ggacacggtg gcactagcgt
     3781 gaccctgggg atggcacact ctactcacca tggctcctgg gactccaccc tggaaaggag
     3841 cccctcatgc ggggggaggg ccagctcacc cctgggcacc tgcaggctag tgaggagagt
     3901 tttttaacct atttttacac gtcgatgcag tccacttctc tttacacaga tgtaccgcaa
     3961 ctcgtgacca gggctggctg ggagggcaac gcagggactg gacgccctac agggccgagc
     4021 ccaggctgtg ctggagggtg gggctggggt gcatggggag gggagcagaa cccagaaccc
     4081 aggagccccg cgtgggccac acccaactca gagccggcct gagcgttcac ggccaggcag
     4141 cctcgcttcc ttgcagccaa gggctggggg ccagggctgc tgttctgcac tctggggtgg
     4201 gtgaggggga ccctgggctg tttgctgtcc caagcccctt ctggaagtta gaagcagcaa
     4261 agggcccggg gaagccgggc atgtgagagg ggtgcgtccc caggtccccc agagggccct
     4321 gtcgccgagg acctttctga aggaagcaga agacgccatt tcctctactt cacactgaac
     4381 tgtcccagcc actgcatcta gggggcattg ggcggaagat ggtgcatttc catggaccat
     4441 tttacactta ccttttaaag caaagcctca ttttctaaac ccctgacttg tgaagcacaa
     4501 ttcagcctcc gggctgggcc acgtggagag agaggatctt ctcagcaagg cgagatcccg
     4561 ggcggcggct gacatcagga gcgccaccct gcgtcctttg ctgctggttc cttactggtt
     4621 tgtacggtca gcgctggaaa cttctattaa atggatgcat tctggaggca tgaagttaca
     4681 agtcaagtcg ccctgctcgt gtttccaagg ctctcacccc tcccagccac cccactttaa
     4741 gggttacaaa cacctgctgg ggtccccacc ccaaccccat aggcaagccc ccattcccca
     4801 gccaggccag gacagtcctt ccaaaactcg ggaaccaaat tgtatttggc tactggtgac
     4861 tggatcctgg tagccaggaa acctgcctgg tggtgggggt cccagagtcc aggagggctg
     4921 tctggtgagc tgcccatcag cctcacccct gcagccaggc atgtccctgg ggtgggcaca
     4981 gagaccccag gctctgcccg cagtggcaca gaactcatct gaggccagtg gctgctgggg
     5041 atcccctaca ctgggggtca gggctgcccc aggtggggat gtgtgtgcac ctcaccacgt
     5101 tcacttcagg gtaccccaag aggctgaagg ggaaggacca aaaggccgag gtgcagcccc
     5161 tccccggtgt cagggcagac aacacagcag ctgctggagg ggccggccct ggccacacag
     5221 actagctagt cccttactcc cggcctgtct ggaaccctcc tgctcagaag gtgcccacta
     5281 gccctctgtg ggggacagag ccagacatgg gtggtcaggg agaggctgtg tggattcagg
     5341 ggaccagaaa gtaagtccca ggaccttgat ggagcggcag ggattgatgt tgggctaggg
     5401 tggccagagc ctgtcccagc agggctgggg tctatcacgt tcctgggatc caagcagcga
     5461 gcacgccctg ccccgcagtc accccgcccc gcagtcgccc tgcagctgga aggcccaagt
     5521 ctgcctcacc tgggtggcct ctcatgtccc ccacaccctg gcccccaggc gaggggggct
     5581 gcacagcacc tgcagggagg agaagggaga gaaaagccgg tctggctgct gggatgggag
     5641 ggccacagtt ccagcagtgg caggggaagc tgtagcccct ggagccccac actggaagag
     5701 ctggcctgca ggaggcacca tgggggagtc gcatgactta ttcgggattg acttgcgatg
     5761 tggatggtgt tcccggagtc ccctgtggcc actccaccac catgaggccg ggaggcatct
     5821 tagcctttga gcctctctcc aggggtgagc ggagcccccc aaagagggct gaaggcttgc
     5881 tgcccaagag gggctgggtg agcacttggg gcctctgaga acatcagtgg tccgttccct
     5941 cctgcacact ggtggcaagt ggcagcattt tttcataatc tccagtaatg aggccacttc
     6001 gggtccagcc ctggacatcc gaggaggagg cgggcagtcc ctgccccttc actaaccgca
     6061 gaggatgcca gctctaggcc ccctgctccg cctggagctc atgcgggcag ccgtggacac
     6121 aggtggcacc cagcgcccag cggcctgtga atcctcccgt gggcaaagct gggagccagg
     6181 ggctggaacc aggcaggtca gtgactgtga gatgccagct gccagcccaa gaaaagctgc
     6241 ctgcagcatc tggaaacttc tgtgctctcc ttggcctctg tgttcttcat ctccaggttt
     6301 agggagcacc cgggtgcctc tctgcttgtc ccgagcccac tcaccaacag ccccagcttg
     6361 cacagtcatg acatcaggaa ggtgggtccc tgctcccagc cgtcctcgtc caccatcact
     6421 tctcccagcc tcgtgtcctg ctgacccata aaaggtcccc ctgcaaagta caccaagtga
     6481 agtaggatct gagcaaaggt tgagggactg aattccctaa gaagtcatca ctgcctagaa
     6541 taagcgaaaa gaattttttt taatgtttta cggtagaatt atttgaaaca tacaaaatga
     6601 gtgagacacc tgctattttc cttattcctg ttttttgttt gtttttattt tccttatacc
     6661 taattcatct aacagaaaac tgggcagggc gcagtgtctc acacctgtaa tcccagcact
     6721 ttgggaggcc aaggcaggtg gactgcttga gcccaggagt tgagtttaag atcagcgtgg
     6781 gcaacatgat gaaccctgac tgtatcaaaa agtacaaaaa aaaaaatagc tagacgtggt
     6841 ggcatgtgca tacagtccca ggtacccaag aggctgagga aggaggatca cctgagctgg
     6901 ggaggttgag gctgccgtga gctgagatgg caccactgca ctccagcctg ggtggcagag
     6961 agagaccctg tctcaaacaa aacaaacaaa caaaaaagaa aaagaaaata aaactgtttg
     7021 ctcaaaatca gaa
//
