LOCUS       NM_138318               7181 bp    mRNA    linear   PRI 21-SEP-2024
DEFINITION  Homo sapiens potassium two pore domain channel subfamily K member
            10 (KCNK10), transcript variant 3, mRNA.
ACCESSION   NM_138318
VERSION     NM_138318.3
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7181)
  AUTHORS   Sorum,B., Docter,T., Panico,V., Rietmeijer,R.A. and Brohawn,S.G.
  TITLE     Tension activation of mechanosensitive two-pore domain K+ channels
            TRAAK, TREK-1, and TREK-2
  JOURNAL   Nat Commun 15 (1), 3142 (2024)
   PUBMED   38605031
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7181)
  AUTHORS   Kim,S.S., Park,J., Kim,E., Hwang,E.M. and Park,J.Y.
  TITLE     beta-COP Suppresses the Surface Expression of the TREK2
  JOURNAL   Cells 12 (11), 1500 (2023)
   PUBMED   37296621
  REMARK    GeneRIF: beta-COP Suppresses the Surface Expression of the TREK2.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 7181)
  AUTHORS   Conrad,L.J., Proks,P. and Tucker,S.J.
  TITLE     Effects of ionic strength on gating and permeation of TREK-2 K2P
            channels
  JOURNAL   PLoS One 16 (10), e0258275 (2021)
   PUBMED   34618865
  REMARK    GeneRIF: Effects of ionic strength on gating and permeation of
            TREK-2 K2P channels.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 7181)
  AUTHORS   Zhuo,R.G., Peng,P., Zheng,J.Q., Zhang,Y.L., Wen,L., Wei,X.L. and
            Ma,X.Y.
  TITLE     The glycine hinge of transmembrane segment 2 modulates the
            subcellular localization and gating properties in TREK channels
  JOURNAL   Biochem Biophys Res Commun 490 (3), 1125-1131 (2017)
   PUBMED   28676394
  REMARK    GeneRIF: The M2-glycine hinge controls the macroscopic currents of
            TREK1 channels.
REFERENCE   5  (bases 1 to 7181)
  AUTHORS   McClenaghan,C., Schewe,M., Aryal,P., Carpenter,E.P., Baukrowitz,T.
            and Tucker,S.J.
  TITLE     Polymodal activation of the TREK-2 K2P channel produces
            structurally distinct open states
  JOURNAL   J Gen Physiol 147 (6), 497-505 (2016)
   PUBMED   27241700
REFERENCE   6  (bases 1 to 7181)
  AUTHORS   Goldstein,S.A., Bayliss,D.A., Kim,D., Lesage,F., Plant,L.D. and
            Rajan,S.
  TITLE     International Union of Pharmacology. LV. Nomenclature and molecular
            relationships of two-P potassium channels
  JOURNAL   Pharmacol Rev 57 (4), 527-540 (2005)
   PUBMED   16382106
  REMARK    Review article
REFERENCE   7  (bases 1 to 7181)
  AUTHORS   Gu,W., Schlichthorl,G., Hirsch,J.R., Engels,H., Karschin,C.,
            Karschin,A., Derst,C., Steinlein,O.K. and Daut,J.
  TITLE     Expression pattern and functional characteristics of two novel
            splice variants of the two-pore-domain potassium channel TREK-2
  JOURNAL   J Physiol 539 (Pt 3), 657-668 (2002)
   PUBMED   11897838
  REMARK    GeneRIF: Expression pattern and functional characteristics of two
            novel splice variants of the two-pore-domain potassium channel
            TREK-2.
REFERENCE   8  (bases 1 to 7181)
  AUTHORS   Goldstein,S.A., Bockenhauer,D., O'Kelly,I. and Zilberberg,N.
  TITLE     Potassium leak channels and the KCNK family of two-P-domain
            subunits
  JOURNAL   Nat Rev Neurosci 2 (3), 175-184 (2001)
   PUBMED   11256078
  REMARK    Review article
REFERENCE   9  (bases 1 to 7181)
  AUTHORS   Lesage,F., Terrenoire,C., Romey,G. and Lazdunski,M.
  TITLE     Human TREK2, a 2P domain mechano-sensitive K+ channel with multiple
            regulations by polyunsaturated fatty acids, lysophospholipids, and
            Gs, Gi, and Gq protein-coupled receptors
  JOURNAL   J Biol Chem 275 (37), 28398-28405 (2000)
   PUBMED   10880510
REFERENCE   10 (bases 1 to 7181)
  AUTHORS   Bang,H., Kim,Y. and Kim,D.
  TITLE     TREK-2, a new member of the mechanosensitive tandem-pore K+ channel
            family
  JOURNAL   J Biol Chem 275 (23), 17412-17419 (2000)
   PUBMED   10747911
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AF385399.1, BC075021.2,
            EU978940.1, AF279890.1, AL133279.7, AI693366.1 and U79244.1.
            
            On Aug 13, 2020 this sequence version replaced NM_138318.2.
            
            Summary: The protein encoded by this gene belongs to the family of
            potassium channel proteins containing two pore-forming P domains.
            This channel is an open rectifier which primarily passes outward
            current under physiological K+ concentrations, and is stimulated
            strongly by arachidonic acid and to a lesser degree by membrane
            stretching, intracellular acidification, and general anaesthetics.
            Several alternatively spliced transcript variants encoding
            different isoforms have been identified for this gene. [provided by
            RefSeq, Sep 2008].
            
            Transcript Variant: This variant (3, also known as TREK2 splice
            variant b) has a different 5' terminal exon compared to transcript
            variant 1, and encodes a slightly longer isoform (3) with a
            distinct N-terminus compared to isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF385399.1, EU978941.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2144835 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-66                AF385399.1         1-66
            67-87               AF385399.1         68-88
            88-1797             BC075021.2         7-1716
            1798-2060           EU978940.1         1704-1966
            2061-2393           AF279890.1         2398-2730
            2394-3326           AL133279.7         85446-86378         c
            3327-3872           AI693366.1         2-547               c
            3873-6317           AL133279.7         82455-84899         c
            6318-7181           U79244.1           1-864
FEATURES             Location/Qualifiers
     source          1..7181
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q31.3"
     gene            1..7181
                     /gene="KCNK10"
                     /gene_synonym="K2p10.1; PPP1R97; TREK-2; TREK2"
                     /note="potassium two pore domain channel subfamily K
                     member 10"
                     /db_xref="GeneID:54207"
                     /db_xref="HGNC:HGNC:6273"
                     /db_xref="MIM:605873"
     exon            1..174
                     /gene="KCNK10"
                     /gene_synonym="K2p10.1; PPP1R97; TREK-2; TREK2"
                     /inference="alignment:Splign:2.1.0"
     CDS             123..1754
                     /gene="KCNK10"
                     /gene_synonym="K2p10.1; PPP1R97; TREK-2; TREK2"
                     /note="isoform 3 is encoded by transcript variant 3;
                     outward rectifying potassium channel protein TREK-2; 2P
                     domain potassium channel TREK2; potassium channel TREK-2;
                     TWIK-related K+ channel 2; TREK-2 K(+) channel subunit;
                     protein phosphatase 1, regulatory subunit 97; potassium
                     channel, subfamily K, member 10; potassium channel, two
                     pore domain subfamily K, member 10"
                     /codon_start=1
                     /product="potassium channel subfamily K member 10 isoform
                     3"
                     /protein_id="NP_612191.1"
                     /db_xref="CCDS:CCDS9882.1"
                     /db_xref="GeneID:54207"
                     /db_xref="HGNC:HGNC:6273"
                     /db_xref="MIM:605873"
                     /translation="MEDGFKGDRTEGCRSDSVAVPAAAPVCQPKSATNGQPPAPAPTP
                     TPRLSISSRATVVARMEGTSQGGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPF
                     ESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSPIGNSSNNSSHWDLG
                     SAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKS
                     IARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVV
                     VTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGDWLRVLSKKT
                     KEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSMERRRLGLDQRAH
                     SLDMLSPEKRSVFAALDTGRFKASSQESINNRPNNLRLKGPEQLNKHGQGASEDNIIN
                     KFGSTSRLTKRKNKDLKKTLPEDVQKIYKTFRNYSLDEEKKEEETEKMCNSDNSSTAM
                     LTDCIQQHAELENGMIPTDTKDREPENNSLLEDRN"
     exon            175..524
                     /gene="KCNK10"
                     /gene_synonym="K2p10.1; PPP1R97; TREK-2; TREK2"
                     /inference="alignment:Splign:2.1.0"
     exon            525..642
                     /gene="KCNK10"
                     /gene_synonym="K2p10.1; PPP1R97; TREK-2; TREK2"
                     /inference="alignment:Splign:2.1.0"
     exon            643..803
                     /gene="KCNK10"
                     /gene_synonym="K2p10.1; PPP1R97; TREK-2; TREK2"
                     /inference="alignment:Splign:2.1.0"
     exon            804..990
                     /gene="KCNK10"
                     /gene_synonym="K2p10.1; PPP1R97; TREK-2; TREK2"
                     /inference="alignment:Splign:2.1.0"
     exon            991..1133
                     /gene="KCNK10"
                     /gene_synonym="K2p10.1; PPP1R97; TREK-2; TREK2"
                     /inference="alignment:Splign:2.1.0"
     exon            1134..7181
                     /gene="KCNK10"
                     /gene_synonym="K2p10.1; PPP1R97; TREK-2; TREK2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3851..3856
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KCNK10"
                     /gene_synonym="K2p10.1; PPP1R97; TREK-2; TREK2"
                     /note="hexamer: ATTAAA"
     polyA_site      3876
                     /gene="KCNK10"
                     /gene_synonym="K2p10.1; PPP1R97; TREK-2; TREK2"
                     /note="major polyA site"
     regulatory      7157..7162
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KCNK10"
                     /gene_synonym="K2p10.1; PPP1R97; TREK-2; TREK2"
                     /note="hexamer: AACAAA"
     polyA_site      7181
                     /gene="KCNK10"
                     /gene_synonym="K2p10.1; PPP1R97; TREK-2; TREK2"
                     /note="major polyA site"
ORIGIN      
        1 gcaaggcatg gagcctgcac tttactctga atgttggtgg cgccttcaga gcattgttag
       61 caagggtcca tgtgatcaca ctgacacctg agagagtgac acaccatgta catggctggt
      121 atatggagga tggatttaag ggggacagga ctgaaggctg tcgcagtgat tcagtggccg
      181 ttcccgcagc agcaccggtg tgccagccca agagcgccac taacgggcaa cccccggctc
      241 cggctccgac tccaactccg cgcctgtcca tttcctcccg agccacagtg gtagccagga
      301 tggaaggcac ctcccaaggg ggcttgcaga ccgtcatgaa gtggaagacg gtggttgcca
      361 tctttgtggt tgtggtggtc taccttgtca ctggcggtct tgtcttccgg gcattggagc
      421 agccctttga gagcagccag aagaatacca tcgccttgga gaaggcggaa ttcctgcggg
      481 atcatgtctg tgtgagcccc caggagctgg agacgttgat ccagcatgct cttgatgctg
      541 acaatgcggg agtcagtcca ataggaaact cttccaacaa cagcagccac tgggacctcg
      601 gcagtgcctt tttctttgct ggaactgtca ttacgaccat agggtatggg aatattgctc
      661 cgagcactga aggaggcaaa atcttttgta ttttatatgc catctttgga attccactct
      721 ttggtttctt attggctgga attggagacc aacttggaac catctttggg aaaagcattg
      781 caagagtgga gaaggtcttt cgaaaaaagc aagtgagtca gaccaagatc cgggtcatct
      841 caaccatcct gttcatcttg gccggctgca ttgtgtttgt gacgatccct gctgtcatct
      901 ttaagtacat cgagggctgg acggccttgg agtccattta ctttgtggtg gtcactctga
      961 ccacggtggg ctttggtgat tttgtggcag ggggaaacgc tggcatcaat tatcgggagt
     1021 ggtataagcc cctagtgtgg ttttggatcc ttgttggcct tgcctacttt gcagctgtcc
     1081 tcagtatgat cggagattgg ctacgggttc tgtccaaaaa gacaaaagaa gaggtgggtg
     1141 aaatcaaggc ccatgcggca gagtggaagg ccaatgtcac ggctgagttc cgggagacac
     1201 ggcgaaggct cagcgtggag atccacgata agctgcagcg ggcggccacc atccgcagca
     1261 tggagcgccg gcggctgggc ctggaccagc gggcccactc actggacatg ctgtcccccg
     1321 agaagcgctc tgtctttgct gccctggaca ccggccgctt caaggcctca tcccaggaga
     1381 gcatcaacaa ccggcccaac aacctgcgcc tgaaggggcc ggagcagctg aacaagcatg
     1441 ggcagggtgc gtccgaggac aacatcatca acaagttcgg gtccacctcc agactcacca
     1501 agaggaaaaa caaggacctc aaaaagacct tgcccgagga cgttcagaaa atctacaaga
     1561 ccttccggaa ttactccctg gacgaggaga agaaagagga ggagacggaa aagatgtgta
     1621 actcagacaa ctccagcaca gccatgctga cggactgtat ccagcagcac gctgagttgg
     1681 agaacggaat gatacccacg gacaccaaag accgggagcc ggagaacaac tcattacttg
     1741 aagacagaaa ctaaatgtga aggacattgg tcttggactg agcgttgtgt gtgtgtgtgt
     1801 gtgtgttttt aatattcaca ctgagacatg tgccttaaac agacttttta gtccaaaatt
     1861 acatagcatt gaagaatata tttcactgtg ccataaacaa ctgaaagctt gctctgccaa
     1921 aaggaatcag agaacaagaa cttcatttca gatagcaaac gcaggacaca ccaagagtgt
     1981 ccgtgcacgt agccggttct ggccgtacat gttaagggca tttcagtggc agtgctgtac
     2041 ccctgggcag tgctacctgg gcacacacgt agacaagggc agctattcct tagaccagcc
     2101 tcctgaaaga aacaggtgtg tctttttagt ggagtcgtag taatatgtgc acacacagaa
     2161 ggggacctga ttgggtggga gctggttatg tgtaactagc gttggagttg acattttggc
     2221 atgtgctctg agcttgaatt ttgataccaa ccattcagtg catcatacct agtctttcta
     2281 tgctccaaat gaatgtctgt ggggacctga gagcacctgg aatttgttgg aagcagatca
     2341 gagcacacgt acgaaaaggt gcaattgctt ttctcatgac aaaagaaaaa aaataatcac
     2401 aaacacatca cactgtggat atcaccttaa ccaatgacag aagcctgctg agtttggtct
     2461 ttctcacagg ggtaggtagt ccacatgaac tggcgagcag tggtgaaaac atgacatcaa
     2521 ctgctgcgtg gttaaaggcc aatcatgcat tttcctcagt gggtgcaatg gtgacaataa
     2581 actgatttgg aaatgtccat gtactttggt tataacttgt tttgataaga ggggtagaaa
     2641 taccaaaaca attgccttgc atgatgccag tggcttgctg ttctgtctag ctgatcctac
     2701 atttttacaa aagtagacat cctgcatttc tgagacacac tgaggaggac catggcatct
     2761 ttccatctca gggctttttg tcccttgggt gtcttagggt agacatagtg ataagatcca
     2821 atctcgctat ctccaaacaa aaagaaaatg taccccttgt acagtaagct tgaaatgttt
     2881 ttattgcttg cagcgtaagt gccattaatt ccatttaaca atgatactta gaaatattta
     2941 aaatatttca ttttactttt atgtttgggc attcctttat tctgaaaaag tcaccactgc
     3001 tccttgcttg tttctacatc tcacatcggt tactcactaa aactggaaca ccctagactg
     3061 attgttccca ggcaaacgat aagctaacac atcataatta tgattggtct gtgaggctag
     3121 aacatcccgc agaggaaagt cggggaatgg ctagtcatag gttgcatgat gattttaaat
     3181 gggtttgtat cagaaagggg aaaatacata ctcctgtgta tgcctcagtc tttatcataa
     3241 ttggctggtt cacagctagc tctttgggcc acacgtgaaa gcatttggac ctggcaacac
     3301 caggcagttg ctggttatgg gtgttctagg ctcactgcta ccttttacag agttcacggg
     3361 attttacgta actaacccgc agtgtggatt taccaaaaga tcacagcact agcggagact
     3421 tccagaaact gtctcatgct ttctgacctc cagggaaagt tgtacccacg acatcctcaa
     3481 ccactggtac catggaagac ctgtccctgc ccatttctca aaaatgcaca gctcttccct
     3541 gcctggagca catgaagtcc catctccctg tccccagacc tttaggctct gttgaagttc
     3601 tggcattgct tatgagaccc ttcctgtcca aggaaggtct aagtcaactc ctccattgga
     3661 ctggagatga ggctcactgg tgacatcctg tgtcgactca gtaataaata gtcacttggg
     3721 aggcgatgtt tatgcaggtg tggatgttga gttttactat gggaatcatt ccagcctgac
     3781 aaaatgtgtt ttaaggaata ggtagataac tgggacttcc tctgttattc taacaagtcg
     3841 aagcttccta attaaactgt ccatggatct cacttatttg gtttccactc tgtgttatct
     3901 ggtacgttct ttgtagcagt gtgttaaaat tccaggccct acggccaaat ctggcagagg
     3961 cttccctctc atttatccag tgccttctgt gggccaggca caggattagg cactttatga
     4021 acgtcagctc attgaaactt cacgacacta tgtgggaagt atttgcaaac ccattatata
     4081 cacaaggaca cagaggctca gggaagctat gttatttatc caatggcaca cagcaagaaa
     4141 gtggtagagc tggtattcaa agtctgacca aagtctgctt tcaacttcac tacagtgtct
     4201 gtgtcatgca tccttgtgat tgtgtgtgtt tgtgtgtatg tgtgtctttc tagcttcatg
     4261 gacacagctt acagatgtgg ggagcagata tggtggaatc tccaccacca agagggcaca
     4321 aggtctttgt gtaaacatgg ctcaaagggt tgcccctgca gacacctact gtacatttat
     4381 ttggttttgg aaattttgta tgtggcaccc tttaaaaaat gccctttgaa agcactcttt
     4441 tgcactttac ttgctaactt tgtagaaact ctgcatacag caggaataaa atagttcaaa
     4501 gcactaagct gcatactcta ccaaatggaa caggtgcatg tgttggtatg tgcatagatg
     4561 cttccccaaa tgagtcaaat cagtcacaca gagggatcaa acataacctt gggctggggg
     4621 tgggaaaatt ttctacataa cccattccct gagacatttg gccaagaatg tgatgaacaa
     4681 aatcaaagaa gatcctctat ggtgattgat cgattaaata tgtgtgcaaa gtgtttagaa
     4741 acctatgaaa tactctcgca aagatgctga gagagaataa gaggttggat tcctcttcat
     4801 ataaactaat tttggaggag gccagttggt ttgaagttac ttgaatgtta ccttttttag
     4861 atggggccaa atggcatgta gaatacacgt gataggtcaa agctgctaca cattctatac
     4921 atgcatcagc acagcccccc ctttccaatc tgcactccca ttccagcata aacctaggag
     4981 aaatgtttcg atttcacaca aagaaagagc acacgtccac catcttcagt gggggctgtc
     5041 ttttgcttca ctggcaagca ggcactgaat ttttcttgca tgacaaatct ggaggtttac
     5101 tggtgagaga gccaatgggc attttttcct ggaaagagta cagctccata cccagtccta
     5161 acccaacagt gatatttatc actttggggc agggctgtat agagtgtgtg tgtgtgtgtg
     5221 tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgcgggttgg ggtggtgttg ggccatctct
     5281 ggcctgttac taaggtaact aggactattt gtgttccagc agtcatagcc tgtgattgtg
     5341 ggtgcatcag ttctctgcct agatctcttg ttaccttgtc tgcacatcaa gggagggagt
     5401 tgagcacaga tacttgtcaa gggccattgt agttgtgcag ttctctaatg aaacactccc
     5461 tagtccatga gttcacaaaa tttattaaga ttaaattata agttggattt gtgaataatg
     5521 actaattaat tgtcttgccc attttaggtt aaggtgagag cttagtctct tgccctttgg
     5581 gatttgtctt ttgggggatt aatggagacc agatgtactt gggagactgg tgtccaaatt
     5641 cggatcatgc cctgtgtagg ctctctctat cctcccttat agctctttag tgtactgtca
     5701 ccgggagggc tcatgctgtg agggcatttt ttgcatggtg ttaagactag ttaaagaaat
     5761 tttaagctgt tgttatttgc agtcaattgt agtacttcat gtatcatgaa ttcaagtact
     5821 atgatcagac agacatctct ctctctctca cacacacaca cacacacaca cacgcacaca
     5881 tacacacaca cacacacacc tgaggaaatg gctgctttgg gttctataag gaccattcca
     5941 tgtttaaagt cctagttgag ctgaatgcta agaacctgcc cccttgcctc cctctgagat
     6001 gatatcattt cctggcttcg tcaatgctgc ctgtctattt gcatgctggg ttctgaggac
     6061 tagtgagaag gtgaccagag tttgggtggg gctggttttt acccactgga tttggtgaga
     6121 atatgaagca tccagtgtgt accagggttt ctgaaccacg ggaaaggcgt aggaaaacaa
     6181 acattcagag cccctgtaaa acgagaaagg aaaaaccagc cagtgttgca ttccacatct
     6241 ctgcttgttg cattttgcta atatggggtt attctttctc actgttagga tgcaattgtg
     6301 tgcaaagaca gtggctgagt gaacagtaag agctggctag taatggcctt aaaaagaaaa
     6361 agggtaactc tctgaaacaa agatcacttt agtgtggcat tgtggatgct gttaattctg
     6421 catagggaaa ctttggaaca gcatgctaat tacatggctg taagcaaagc cctgtcctct
     6481 gtctctgcac cataccttca ttggacttca ccaacccatc catactccat gtaaacctca
     6541 gttctctcat gcctgcccta agtcagttga catcagtgca gtggcattga ggagaaatga
     6601 gaggtgtctc tgattttact gaaagttatt atcattttca caggtgcctg agatttggta
     6661 tctactttgt gttcttgatt cttaggtgaa aaatctgaaa tagttccctg tgcattaaaa
     6721 taaattattt tgagaggact cctgctccgt cgattcagca gacctatgct gcagaaggta
     6781 actgcggaag ctctcttttg ctgtcagggc tctgagcttg aagggagaag gtgcagtggt
     6841 gcctagaagt gatatgcaaa ccacctcaca tgccagcctc tggcctcctt cccatcccag
     6901 agtcacagac aggggaccca gtgacaatga tgataaatcc atgtgtggag gtgttttact
     6961 tatttttctt tccgtaggat ttcatggtgc tttaaaaaaa aaggcatttt acagaaaata
     7021 atgtgggggg agggagattt cataatgttc ttagggaaag tacaaaacaa atttgcttgt
     7081 gacatttcaa taagctgtgc tgctattgtc tttatttgat gatgtaattt ttttttcaat
     7141 gatggagaaa aattgcaaca aagaccttct ggaagatcca a
//
