LOCUS       XM_006712052            7583 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens potassium channel modulatory factor 1
            (KCMF1), transcript variant X2, mRNA.
ACCESSION   XM_006712052
VERSION     XM_006712052.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_006712052.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7583
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..7583
                     /gene="KCMF1"
                     /gene_synonym="DEBT91; FIGC; PCMF; ZZZ1"
                     /note="potassium channel modulatory factor 1; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 2 mRNAs, 31 ESTs, 885 long SRA reads, 7 Proteins, and
                     95% coverage of the annotated genomic feature by RNAseq
                     alignments, including 56 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:56888"
                     /db_xref="HGNC:HGNC:20589"
                     /db_xref="MIM:614719"
     CDS             351..1520
                     /gene="KCMF1"
                     /gene_synonym="DEBT91; FIGC; PCMF; ZZZ1"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase KCMF1 isoform X2"
                     /protein_id="XP_006712115.1"
                     /db_xref="GeneID:56888"
                     /db_xref="HGNC:HGNC:20589"
                     /db_xref="MIM:614719"
                     /translation="MCCLPDQVLENDDGVSCDACLKGNFRGRRYKCLICYDYDLCASC
                     YESGATTTRHTTDHPMQCILTRVDFDLYYGGEAFSVEQPQSFTCPYCGKMGYTETSLQ
                     EHVTSEHAETSTEVICPICAALPGGDPNHVTDDFAAHLTLEHRAPRDLDESSGVRHVR
                     RMFHPGRGLGGPRARRSNMHFTSSSTGGLSSSQSSYSPSNREAMDPIAELLSQLSGVR
                     RSAGGQLNSSGPSASQLQQLQMQLQLERQHAQAARQQLETARNATRRTNTSSVTTTIT
                     QSTATTNIANTESSQQTLQNSQFLLTRLNDPKMSETERQSMESERADRSLFVQELLLS
                     TLVREESSSSDEDDRGEMADFGAMGCVDIMPLDVALENLNLKESNKGNEPPPPPL"
ORIGIN      
        1 gccgccccgg aagagcccgg tgtggtcgca gagccgggcc gcgggcggca gcaggaggca
       61 aaagagccgg cccgggaccc ggcaggcgcg tccggtcgcc gggagacgac ggcgagtgtc
      121 cccgcctgcg ggcgaccgcg gggctggcgg gaaggctctg cggccaaggg acgggaagcc
      181 ctcgccgcct ggagcccgcc ccggcctcgc ggctaggcct cggcgcgtcc ctgggctcgg
      241 gtaaccaagt tcccggggtg gatccgaccc cgccgcagca agcaaactcc ctgctcagtc
      301 acccaggcgg agcagggctc gctccccgcg gccctggtgc cctcgccggc atgtgctgcc
      361 taccagacca ggttttggaa aatgacgatg gtgtcagctg tgatgcatgt ttaaaaggaa
      421 attttcgagg tcgcagatat aagtgtttaa tttgctacga ttacgatctt tgtgcatctt
      481 gttatgaaag tggtgcaaca acaacaaggc atacaactga ccacccaatg cagtgcatat
      541 taacaagggt agattttgat ttatactatg gtggggaagc tttctctgta gagcagccac
      601 agtcttttac ttgtccctat tgtggaaaaa tgggctatac ggagacatct cttcaagaac
      661 atgttacttc tgaacatgca gaaacatcaa cagaagtgat ttgtccaata tgtgcagcgt
      721 tacctggagg cgatcctaat catgtcacgg atgactttgc agctcatctt acacttgaac
      781 acagagcccc tagagattta gatgaatcga gtggtgttcg acatgtacgt agaatgtttc
      841 accctggccg gggattagga ggtcctcgtg ctcgtagatc aaacatgcac tttactagca
      901 gttctactgg tggactttct tcttctcaga gttcatattc tccaagcaat agggaagcca
      961 tggatcctat agctgagctt ttatctcagt tatcaggagt gagacgttct gcaggaggac
     1021 agcttaattc ctctggccct tccgcttctc agttacaaca actgcagatg cagctgcagc
     1081 tagaacggca gcatgcccag gcagcacggc aacaactgga gaccgcacgc aacgcaaccc
     1141 ggcgtactaa cacaagcagt gtcaccacta caatcacaca atccacagca acaaccaaca
     1201 tagctaatac agaaagcagt cagcagactc tacagaattc ccagtttctt ttaacaaggt
     1261 tgaatgatcc taaaatgtct gaaacggagc gccagtccat ggaaagcgag cgtgcagacc
     1321 gcagcctgtt tgtccaagag ctccttctgt ccactttagt gcgtgaagag agctcatcct
     1381 cagatgagga tgatcggggg gagatggcag attttggtgc tatgggctgt gtagatatta
     1441 tgcctttaga tgttgcttta gaaaacctaa atttaaaaga gagtaataaa ggaaatgagc
     1501 ctccaccacc tcctctttga tgacatccca attcgcagac aatgtcctct gtgctgtatt
     1561 tgccaatgaa agtggacaac aactatcttg ggtttgtttg gtgattgtaa tttcaggtct
     1621 gtcactcttg ttacattgtg tacattcaaa aggaagagag aaaatatata tgataatcat
     1681 ttccacttaa ctaattttta cttctagcag gtaaatgtag gtagcagtgc aggggtgatc
     1741 tctgcttcct gtaccttgac atgcaaaagg ctctcctaat actccacatt caaactgaag
     1801 aggaaaattg aaatctctaa tgaagctgct gtgtgtattt atgaatatta atgaataaaa
     1861 actgcttgga tggtttacct taactactgc atgaggtttt ttgcagcgtg catgagtttt
     1921 agtgaccttg ttatttaaga agttaaatac aaggagtaaa acttaaaaaa aaaatacaaa
     1981 gcccaaagct ttcccaaaca ttattcaatg gttacacgac gaagtagctt ttgaataatg
     2041 tctgcctgaa tcacctttct ttgtgtgcct cctacgcaca aagccagctc tgcagtggaa
     2101 tctggggatt atagccgggt gtggcactcc gccctgtgtg actgtcctgt cgccctgtta
     2161 gtcatcttgc ctgtgtggag ctcagcctgt ctctttaact catctgtaga agacacacca
     2221 gtaaagctac tgttggaatc tgctgcaggg gcctttgtgt gccctaaaaa caaatcctgt
     2281 tcatgtttgt ttaaagtttt tactttttgt ggttgtttaa aattttttca attgttaaat
     2341 atgttttatt caggtgtaga tgaatttcat ttattgactg ttcaacagag ttaacctgaa
     2401 ttatgttgtc tttgttttta aaaatctcac attctcaatc atattttgca ttatttatgt
     2461 atttgctttg tagtttgctg agacagatca gtatcagggg agctttgagg atttgccttc
     2521 ccagatttgt cagtatatta caaccaaatt cttaatgcta attttagcac cttttattta
     2581 ttgggttttt tctggcataa aaagtaaagc cttttaattg aatcatgcca cctatatgcc
     2641 tatattatta atcctatgtg taaaaaaaat gtacagcttt ttttgggttt gttttggggt
     2701 ttggaagggc cgggttattt tttatttcct gtttcagttt ttgtgcatag actttcacaa
     2761 tagctccaag gcagggacag cgggtttggg ggttgggagg gcagtttttg gaatgtaaat
     2821 ttaggacttt taaaaaggtg cgcacagctt ctgataaatt tataactaga cttaacctaa
     2881 tcatgtctcg ttccagttct cttttctctg agcccttttc aaagtctcct ctctttctcc
     2941 tgtcatcctt ttcctttcct gtccgtgtat ctccgtttct tcaacatgac aagcatacag
     3001 acttgaacac ccctccggtg ttcttccgag aactgtgaag tccatgttca tccaaatgta
     3061 accaaaaaag aagtcaccct acatgtctga aaaactgttg cttctcctct gaaacttcaa
     3121 actccaacga tttccaaata caatagcttt gttttcttta gttctgtaat ggataatgtt
     3181 taaaggaaaa ctttacacca ggcttctggt tacactagaa gtcaagccca ttagggattt
     3241 tcattttttt tcatttggtt gttgagaagt ttcaaaaatc agttttcaag ctgtggtctt
     3301 tcaaacacat ctgcacataa gtcacacatt tcaataaagc attttcaaga ctgttgacca
     3361 cttgaatttc tttggtgtta gtggattaac ctaaccatta ctctgagatt ttatatctct
     3421 aatccagtat tttttttctt tttatgctaa acatgggaga tcctggtttt gtgtgaatgc
     3481 attattttgg atgtgagaaa taaatgccaa ttatatgtac tttccctttt ctgcacaaat
     3541 tctgggaaaa tgtaaaagcc ttcatttttt aacatggttt tagggaacaa ctgtaagtcc
     3601 attcagagca gtttaattta gatgatcact tttaacactg cagaagacct aaggagtcat
     3661 aagattccat ctcatgtaga atactgtata ttaattattt tttaccagat attttacaaa
     3721 tacctcacct catcctgtat gtaatcaata atgtattatt ttagggtaga acgacacaga
     3781 atatcaatat aaaaatatat tcaagccctt gaaattcttg tgtccttttt ctttagtttc
     3841 tgaatgaaaa tcttattact ggatgtacta ttgaataaaa attaattgca aagactttga
     3901 tggagacaaa atcaaaatat accactgttt attttggcag caccttcaaa tttctaagga
     3961 ccagatcctg aattttgaga attttttgtt tcgttgagtt ttgagtgtct aggatataag
     4021 tttataaatg ttctacagtg cttgtcttta cttcctgttt agaaatcatt taaatctttc
     4081 ccctcgaggt gctctggaag aagtttaatt tcagctctga acaagtagaa ataactgtgc
     4141 ttccttgtat ggctgcaatc ataagacaga atttctgtgg ttggctaccg tgaaatcttt
     4201 gtatttatat tgcattgttt tgttaaaaaa aaaaaaatcc acagaagtag aacctaggtt
     4261 tgctactaac aaagtagtgg attcttataa ttaggctcag gtaaagtaag agaaaacttc
     4321 tctccctgtg gcccccagag aaatgaagta ggatagcaga ttacactatt agaaataata
     4381 gacgtaacaa aaaaaatcca gcccattatc cccacccccc attttccctc tcaatattag
     4441 aaatttcaat aatatgctga cagattttca aaggtcacca aggcttttgt gtttttttcc
     4501 ggtctgtggg ccacagttaa aagaacgggt aacaggttca gagttctctt gatacgtcca
     4561 agccttagtt tccaggaaaa aagctaggct cctcactgca aatattaacg ctttatatat
     4621 ttactccatg gatgttgggg taagcacata tatcaatagt tcatagctct agttaaggac
     4681 aaagtgggtt ggggggtaga aggagaatac tagagaggtt acggtagcag gtggctgcag
     4741 aaaagaatct tttgaatggg attcctgtaa cagtgttcag taccaatatt aagtctactg
     4801 taagtggggt ctgatatggc ttactgatac aggcatgtgt aaaaaactaa gtgtgatgga
     4861 ggaatgggtg ctaaaagctc ttaacagttt tgtagagaag ccctgcagcc gtgtttacta
     4921 tatatgacat gcctgtttct tagtttgcat gcacagttta aggggcacat gcaatattgg
     4981 tttcatgtgc agtaaaaatt aaaacacggc tgagcgtggt ggctcacgcc tgtaatccca
     5041 gcactttgcg aggccgaggc gggtggatca cgaggtcgag tttgagacca ttttggccag
     5101 catagtgaaa ccccatctct actaaaaaat acaaaaagtt agctgggcat ggtggcaggc
     5161 acctgtaatc ccagctactc gggaggctga ggcaggagaa tcgcttgaac ctgggaggca
     5221 gaggttgcag tgagctgaga tcacgccgcc attgcactcc agcccgggcg acggtgcaag
     5281 actctgtctc aaaaaaaaaa aaaattaaaa cactaggtac gaaattatcc cagaattata
     5341 cgcgaaagtt ggtgttcatg ctggaaaaca gttacggtta tctgtgctct ttctaaagct
     5401 caactagaca ctaaaacagt tctctccttg agaccggaag tgggatgggg gtgggcaggt
     5461 ggaagggaag aggctgggga ggagcctctc atctcatctc atttcagcct caacagtaat
     5521 tgaaacccta tgcctggcct ggagtgggta gaggttaggg ttagagtgca ggatggagca
     5581 gcagtctgca gactttcagg ttgtgacgat gtcatgaaat tctgtgctat taaacatggc
     5641 tatgtctgag tcagtcatta cggtattcca aagccaaatt caagtgactg tttttctgaa
     5701 tagtataaaa atctaattcc ctgtgcttat cggcttcaac tgtgcttaca caacgtttgt
     5761 ttctaattcg tactcttgcc tcttggtttc tgtagttttt caacccattt ctgtcagtgt
     5821 tctataaatg catacattcg ttatttaagg aaccctgcag cagacctcga ataaaatgtg
     5881 acttgatgtt tgttgccact tcctcaactt ggttagcaaa ttcaagtttt gaaagacgat
     5941 tcgtctcaga gaagttgatc ctgaacctcc acgtcacatt ttagtcggtt gctattaggt
     6001 gggtaatgcc taataacatg ggttcctcaa atcacaaagg agaatgctct caagtcctca
     6061 tgttaacttt agtaagtcag ttaactttac agcaactaaa gagatcaatt aaaaagaacc
     6121 cttaagtctg actgtcccag gtaactttac ttgctgtaca gatagtgcac agatatggat
     6181 gagggctgca catggctgat ttgaaaaccc atgtggggcc gggtgtggtg gctcacgcct
     6241 gtaatcccag cactttggga ggccaaggcg ggtggatcac gaggttagtt caggaccagc
     6301 ctggccaaga tggtgaaacc ccatctctac taaaaatacg aaaattagct gggcttggtg
     6361 gcagatgcct gtaattcctg ctactcggga ggctgaggca gagaattgct tgaacccggg
     6421 aggcggaggt tgcagtgagc cgagattgcg ccactgcact ccagcctggg cgacacagtg
     6481 agactctcct caaaacaaaa aaaaaagaaa gaaaacccat gtgggccgca tgtgcacagc
     6541 ctggggctgc tttccacagg cctggataat gatgtttctc ttcaaggagg cctttactaa
     6601 ccacagggaa cctagcatct gactgtgtcc ttggcagaca gtgcatgtag cctgtagaat
     6661 gttggctcct ctgtctatag aaaccatcag ttcgctgctc tctcattcat acatactttt
     6721 tgagttccca gtaggtacga agctttgtct aaacattatt taccaactgc gatttttaca
     6781 gacttcccct gtaagaattt tctaaaagag cctttctccc ttacacaatt gaaacgtttt
     6841 caaaggtcat caagccggtt gcgtttggtc agtcacgtga ccaatcagag ctggtgagtg
     6901 agctgctccc ttaaatctac caaattagac tgacagcatt tggaatctgc ctcacacata
     6961 agagatccat attcatttaa tagtgaagcc agcccagaag catcctcttc tgtaagctgg
     7021 atggagtccc agctctctct ccttgtatat aaggagacca caccctgtat ataaggtttt
     7081 cttgaggtag atgcagcaat attcctgggg taagattcta taatactcct gtattggcaa
     7141 gtggactgga ccaacagaca caggcctcag ccactgtcgc tagggactga aggagagttc
     7201 atggattctt accccctagt catgaaagct attctggcca gccttgaatc catttaattt
     7261 tgcccacgag aacctttcat gacaattaac aagacactag tttccccata aaagtccatt
     7321 tttaaatata tagtatgcta attagcagtg tctgttgaat tgccctatcg gatagcagcc
     7381 accatgtgtg ctgaccactc acgattcaga cttaccttgg aaaatatcac actgacgata
     7441 cagtacttta gaataaattg catattgtat caggctccga gactaatttg tactgaaccc
     7501 ttgatataga ttacctttta taacatcacc acctgtcatg aagcttatct gttttctgat
     7561 ttgaataaac tttgtgttgt gca
//
