LOCUS       NM_001397448            4250 bp    mRNA    linear   PRI 07-AUG-2024
DEFINITION  Homo sapiens KANTR integral membrane protein (KANTR), transcript
            variant 7, mRNA.
ACCESSION   NM_001397448
VERSION     NM_001397448.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4250)
  AUTHORS   Lagarde,J., Uszczynska-Ratajczak,B., Carbonell,S., Perez-Lluch,S.,
            Abad,A., Davis,C., Gingeras,T.R., Frankish,A., Harrow,J., Guigo,R.
            and Johnson,R.
  TITLE     High-throughput annotation of full-length long noncoding RNAs with
            capture long-read sequencing
  JOURNAL   Nat Genet 49 (12), 1731-1740 (2017)
   PUBMED   29106417
REFERENCE   2  (bases 1 to 4250)
  AUTHORS   Sauvageau,M., Goff,L.A., Lodato,S., Bonev,B., Groff,A.F.,
            Gerhardinger,C., Sanchez-Gomez,D.B., Hacisuleyman,E., Li,E.,
            Spence,M., Liapis,S.C., Mallard,W., Morse,M., Swerdel,M.R.,
            D'Ecclessis,M.F., Moore,J.C., Lai,V., Gong,G., Yancopoulos,G.D.,
            Frendewey,D., Kellis,M., Hart,R.P., Valenzuela,D.M., Arlotta,P. and
            Rinn,J.L.
  TITLE     Multiple knockout mouse models reveal lincRNAs are required for
            life and brain development
  JOURNAL   Elife 2, e01749 (2013)
   PUBMED   24381249
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL591212.11 and AL139396.18.
            
            Summary: This gene is thought to produce a functional long
            non-coding RNA. Mutation of this locus in mouse causes tremors and
            spastic movements, suggesting a role for this gene in neurological
            development or function. [provided by RefSeq, Feb 2015].
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660803.91914.1,
                                           SRR1803613.161748.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN03465403, SAMN03465404
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000604062.7/ ENSP00000492284.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-143               AL591212.11        3913-4055
            144-280             AL591212.11        9243-9379
            281-4250            AL139396.18        10008-13977
FEATURES             Location/Qualifiers
     source          1..4250
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xp11.22"
     gene            1..4250
                     /gene="KANTR"
                     /gene_synonym="LINC01155; Spasm"
                     /note="KANTR integral membrane protein"
                     /db_xref="GeneID:102723508"
                     /db_xref="HGNC:HGNC:49510"
                     /db_xref="MIM:301019"
     exon            1..143
                     /gene="KANTR"
                     /gene_synonym="LINC01155; Spasm"
                     /inference="alignment:Splign:2.1.0"
     exon            144..280
                     /gene="KANTR"
                     /gene_synonym="LINC01155; Spasm"
                     /inference="alignment:Splign:2.1.0"
     exon            281..4250
                     /gene="KANTR"
                     /gene_synonym="LINC01155; Spasm"
                     /inference="alignment:Splign:2.1.0"
     CDS             1085..1315
                     /gene="KANTR"
                     /gene_synonym="LINC01155; Spasm"
                     /note="long intergenic non-protein coding RNA 1155; KDM5C
                     adjacent non-coding transcript"
                     /codon_start=1
                     /product="KDM5C adjacent transcript"
                     /protein_id="NP_001384377.1"
                     /db_xref="CCDS:CCDS94609.1"
                     /db_xref="GeneID:102723508"
                     /db_xref="HGNC:HGNC:49510"
                     /db_xref="MIM:301019"
                     /translation="MSPFSLLILVICAFSLFFLINLTRGLSILLVFSKNQLLALLLLS
                     IVSLFSISLISALIFFDLLPSTFFGFILLFFF"
     regulatory      4225..4230
                     /regulatory_class="polyA_signal_sequence"
                     /gene="KANTR"
                     /gene_synonym="LINC01155; Spasm"
                     /note="hexamer: AATAAA"
     polyA_site      4250
                     /gene="KANTR"
                     /gene_synonym="LINC01155; Spasm"
                     /note="major polyA site"
ORIGIN      
        1 ggtagcggcg taggcccgtg cccctgctcg cgctgcagcc cgtggaaggg ttccgtccag
       61 cgtatccttc agatcttgct gtaggcctct ggtgtctgtg cgcgcgcggc aggggcggcg
      121 gcggcgacgg ccggaggtgt acgttgcttc ctctactgaa gtcttgaaac ccctgaaagt
      181 catccctgag gtttgaagtt aacttcttct acaccctgtt aatgttgata ttttgacctc
      241 cttccatgaa tcacaaatgt tcttaatggc atctagaatg aacatgcatc attattagaa
      301 ccatcaccct gcagctagct tggataccat taaaagggct catcagctgc aaacggatta
      361 aagtatctga tactcgggaa gacagagttt cagggtttct acctggagct acaccctcag
      421 gaagcccctc cttggcctcc ctgcacccag tcccatccca accagtcaca tcttgggctg
      481 tgcgtggtgt ttcttggaaa ctggaacaca gactcctcca gcagctccac aggtcccttg
      541 tcctcaatga gcagaagact acaggagctg gctactgaag aggctgtcca agtaatagag
      601 caccttcttg gccctgctta gcacatttac tgcagagctg gatgctactt atttgtgctc
      661 accaccttca gggactgcag agagatttgt cagaccctac ttcactaagg gccaccctct
      721 aaggatctcc agaagaggct gcccatagag agaagtggcc tgcctagggt ctccacttcc
      781 tcaggtccta cccggacacc tctagggctg aggggatcag tatctcttca cctgcctgta
      841 atccacatac caagtggaag aatctgcctg ctattttttg tttgtttgtt tgttttggcg
      901 ggaagagttt taactactgc tgtaactcct ttagtagcta tggaactgtt gaggatttct
      961 ttttcttctt gagtcgattt tggtaagata acagttttct aggagttggt ccattttgtc
     1021 tgcattttca aattcattgg cataaagttt cctttttatt ctgtgctgtg tatgaactgt
     1081 aacaatgtct cctttttcat tactgatatt ggttatttgt gccttctcac tttttttctt
     1141 gatcaatctc accagaggtt tatctatttt attagtcttt tcaaagaacc aacttttggc
     1201 tttgttgctc ctctctattg tatctttgtt ttctatttct ttaatttctg ctcttatctt
     1261 ttttgatctc cttccttcca cattttttgg gtttattctg ttgttctttt tctaatttaa
     1321 ctggacattg agctcattag ttttcattct ttcccatttt ctaatttgtg catttaagga
     1381 tataatttcc ctctaactcc tgcttctcca taagtttaga tatgtagtat tttcattatt
     1441 gctcagttat aagtacttca tttctatcaa ggttacttct ttgacctgta agttatatag
     1501 aaatgtgttt ttagatttcc aaatgtttgg ggatttaaaa ttttatctct ttgttattga
     1561 aatctgtctt aattgcatta tggtcagagg atgtggtttg tgtgacaaca actctgaaat
     1621 tttttagact tgttttatgg cttagtatgt gaccaatatt tttgaatgct tcctgtgtgc
     1681 taatttataa gaatgtgtgt tctctaattg ttgaatacag agatctacat atgtctatta
     1741 tcaagtttgt gaactattgt tcaattttta cttacctata ctgatttttt tggtcattat
     1801 ctactgataa ttgaaagagg tgcgttaatg ttcaactgta atggtggatt tggcaatttc
     1861 tccttgtaat tctatctcgt ttcttgcttt atatattttg agggtgttca ttaggaatat
     1921 tcaaattaaa aattgttata tattcctgat aaatatgtaa tgaccctctc tattcctgat
     1981 aatgcatttt tctttgaaac ctattttatc ttatattaat gtagtaacac aaacttttct
     2041 tgttgggatt tgtgtggtat ataattttcc atccttttac ttttgagcat tttcatgcca
     2101 ttatgtttaa ttatatctct tggaaacaac atataactgg accttttaaa aaatctaatc
     2161 tgattatctc ttttggttgg caagtttagt ctgtttacat ttactgtgat gtatttgggc
     2221 ttgtttctac catcatactt ttttatttct gtttaccatc actacctttt ctgtgcttca
     2281 ttttctcttt tctcgcctgc ttttttagtt ttgagatttg ttttcttatt caattttttt
     2341 cctccctatt tttaaatttt tttctattct ttctgtggtt atccttgatg ttttccatat
     2401 gtgtttaact tataaagtct aaagttaaac aatattttag cccccttctt aaagaatgca
     2461 ggaagcttag aaaccttcaa ctctagtcat tcctctcctg atcacatact gttgttttca
     2521 aatatgttag tttgttcctt tttataaacc tcacaatttt acatcattgt cagtgttatt
     2581 ttatatagac agtgtttgtt tggacttaca tgcatacatt cttgtatcac acatcatcct
     2641 ttgggatcat tttctttcat tatgaatata gtgtttaagt gagttttttt tttttttagt
     2701 acaggtctct tgatgttaaa ttcttccagt ctttcttata tgtaaatgtc tttattttat
     2761 cctcattctt aaaagatagt ttgttacagg tatttttact caacacttag aatatatggt
     2821 tccattctct tttggctttg agatgtctgt tgctattaag aagtcgacta tcagactaat
     2881 tgctggtttt gtgtgtgtgt gtagtagtag tagtagtagt ggtagtagtg gtagtagtag
     2941 tagtggaatg tgcagggggt cctgcagttt tactctaaca tgtttacata tgtatttttt
     3001 tttaattcta ctttgggaat gtcatgcttc gtggctcagt gaattcatgc ttttcataat
     3061 ttctgggaaa ttctcaacca ttatctcttc aaatattgcc tttcattttt tctagttttt
     3121 ctttcttgga atacagttag tcatattttg gacctcctca ttctatcttc cgtatctcat
     3181 aacatctctg agattttcta tctccttgtc tttctgcact tcattctgga taatttcttt
     3241 aggtatatct ttcagcttac tgattctctt ttcaactatg tttaatctgc tctaatctgc
     3301 ccattgagtt ttttatttca aaagttatat ttttcatttg tacaaacctc atatatttta
     3361 cttgctaatc tgcctagtca tccctaatag tctcttattg cttggtcatc ttagtgatta
     3421 catctgttat tacttcttta aaacatttta tataattttt gttcaaccag tagtcactgt
     3481 ttgcatgagt atgacattgt aaatattgtt cacatcaaaa ctacatagta tattctgatt
     3541 acatatcctt cgttgtatac cctttcgttt tccttggagc taataattgt gtattttgtt
     3601 ttcttttgct tagtgttcta gtacctatac tattcttctc tgaaattctt tatacaatcc
     3661 aaatcagatc atgtccttcc actattcaga attctcccat ggctcccacc tccctcaaca
     3721 aaagccaaag ccctcaccat ggcccaaagt ccctacataa tctggttccc tttacctctc
     3781 ttaccttgtc tcctatcact ctcaatatca ctcactcttc tccagctaca ctggcctcct
     3841 tgctgttccc caagtgtgct agataccctt ccttttcagg gcctttgtac ttgttcttct
     3901 cactgcctga aacacccttc ctcctaaata atctgatgag ttgccctagt acttccagtg
     3961 tgctcaaatg tcacctccct agagaagtgt ttcctgatca acatatctaa aatcgcccca
     4021 tcacatgcat tttatatccc tttatcctat tttatgtatg tttttctaca aagcactgat
     4081 caccacctgg tatattttat atttatttat tgtggttagt gttcgtctct cttcagtaga
     4141 ctgtaagctc cataaagcag ggacttctgt tttgttcact gctgtatccc cagtgccaaa
     4201 aacaacagtg catagtagat actcaataaa tatttgtgga ataaactgaa
//
