LOCUS       XM_047438574            5244 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens KN motif and ankyrin repeat domains 2
            (KANK2), transcript variant X6, mRNA.
ACCESSION   XM_047438574
VERSION     XM_047438574.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000019.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5244
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
     gene            1..5244
                     /gene="KANK2"
                     /gene_synonym="ANKRD25; MXRA3; NPHS16; PPKWH; SIP"
                     /note="KN motif and ankyrin repeat domains 2; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 8 mRNAs, 163 ESTs, 1399 long SRA reads, 7 Proteins,
                     and 99% coverage of the annotated genomic feature by
                     RNAseq alignments, including 108 samples with support for
                     all annotated introns"
                     /db_xref="GeneID:25959"
                     /db_xref="HGNC:HGNC:29300"
                     /db_xref="MIM:614610"
     CDS             401..2956
                     /gene="KANK2"
                     /gene_synonym="ANKRD25; MXRA3; NPHS16; PPKWH; SIP"
                     /codon_start=1
                     /product="KN motif and ankyrin repeat domain-containing
                     protein 2 isoform X2"
                     /protein_id="XP_047294530.1"
                     /db_xref="GeneID:25959"
                     /db_xref="HGNC:HGNC:29300"
                     /db_xref="MIM:614610"
                     /translation="MAQVLHVPAPFPGTPGPASPPAFPAKDPDPPYSVETPYGYRLDL
                     DFLKYVDDIEKGHTLRRVAVQRRPRLSSLPRGPGSWWTSTESLCSNASGDSRHSAYSY
                     CGRGFYPQYGALETRGGFNPRVERTLLDARRRLEDQAATPTGLGSLTPSAAGSTASLV
                     GVGLPPPTPRSSGLSTPVPPSAGHLAHVREQMAGALRKLRQLEEQVKLIPVLQVKLSV
                     LQEEKRQLTVQLKSQKFLGHPTAGRGRSELCLDLPDPPEDPVALETRSVGTWVRERDL
                     GMPDGEAALAAKVAVLETQLKKALQELQAAQARQADPQPQAWPPPDSPVRVDTVRVVE
                     GPREVEVVASTAAGAPAQRAQSLEPYGTGLRALAMPGRPESPPVFRSQEVVETMCPVP
                     AAATSNVHMVKKISITERSCDGAAGLPEVPAESSSSPPGSEVASLTQPEKSTGRVPTQ
                     EPTHREPTRQAASQESEEAGGTGGPPAGVRSIMKRKEEVADPTAHRRSLQFVGVNGGY
                     ESSSEDSSTAENISDNDSTENEAPEPRERVPSVAEAPQLRPAGTAAAKTSRQECQLSR
                     ESQHIPTAEGASGSNTEEEIRMELSPDLISACLALEKYLDNPNALTERELKVAYTTVL
                     QEWLRLACRSDAHPELVRRHLVTFRAMSARLLDYVVNIADSNGNTALHYSVSHANFPV
                     VQQLLDSGVCKVDKQNRAGYSPIMLTALATLKTQDDIETVLQLFRLGNINAKASQAGQ
                     TALMLAVSHGRVDVVKALLACEADVNVQDDDGSTALMCACEHGHKEIAGLLLAVPSCD
                     ISLTDRDGSTALMVALDAGQSEIASMLYSRMNIKCSFAPMSDDESPTSSSAEE"
ORIGIN      
        1 ggcgcgcgcg aagacgctcg ggcggcggga cccagggaag gcagcggccg gagcgcgcaa
       61 ggggtgagcc tccaggcaaa tggaaaacgg aatttcctgc aattggtgac catgtgttcc
      121 aggtgttgaa agacagagaa gcgaagacag agacgtggaa agacagggag agagacacgg
      181 agagagacgc agaaggacag agacgtggag agagacgcag agagacagag acgtggagag
      241 acacagagag acgtggagag acacagagag acttggagag agacaaagca agacaggacg
      301 ggagaacaag gacaagctca ggtaagcctc agccggtgct gcaggcagtc tgactcgcag
      361 tccctcaagt gacttccaag gagcatctgt agaaaagaag atggcccagg tcctgcacgt
      421 gcctgctccc ttcccaggga cccctggccc agcctcccca cctgccttcc ctgccaagga
      481 ccccgatcca ccctactccg tggagacccc ctatggctac cgcctggacc tggacttcct
      541 caagtacgtg gatgacatcg agaagggcca cacgctgcga cgcgtggcag tgcagcgccg
      601 cccccgcctg agctcgctgc cccgtggccc tggctcctgg tggacgtcca ctgagtcgct
      661 gtgctccaat gccagtgggg acagccgcca ctcagcctat tcctactgcg gccgtggctt
      721 ctaccctcag tatggtgctc tggagacccg cggtggcttc aatccgcggg tggagcgcac
      781 gctgctggat gcccgtcgcc gtctcgagga ccaggcggcc acacccaccg gcctgggctc
      841 cctgaccccc agtgcggccg gctcgacagc ctccctggtg ggcgtggggt tgccaccccc
      901 gacaccacgg agttcaggac tgtccacacc ggtgcctccc agtgccgggc acctggccca
      961 cgtgcgggag cagatggcgg gtgccctgcg gaagctgcgg cagctggagg agcaggtgaa
     1021 gctgatccct gtgctccagg tgaagctctc ggtgctccag gaggaaaagc ggcagctcac
     1081 agtacaactt aagagccaga agttcctggg ccaccccaca gcgggccggg gtcgcagcga
     1141 gctctgcctg gacctccccg atcccccaga ggacccagtg gcactggaga cccggagtgt
     1201 gggcacctgg gttcgagaac gggacttggg catgcctgat ggggaggctg ccctcgccgc
     1261 caaggtcgct gtgctggaga cccagctcaa gaaggcgctg caggagctgc aggcagctca
     1321 ggcccggcag gctgaccccc agccccaggc ctggccaccg ccggacagcc cggtccgcgt
     1381 ggatacagtc cgggtggtag aagggccacg ggaggtggag gtggtggcca gcacagccgc
     1441 tggcgccccc gcacagcggg cccagagcct ggagccttac ggcacagggc tgagggccct
     1501 ggcaatgcct ggtaggcctg agagcccacc tgtgttccgc agccaggagg tggtggagac
     1561 aatgtgccca gtgcccgctg cagctaccag caacgtccat atggtgaaga agattagcat
     1621 cacagagcga agctgcgatg gagcagcagg cctcccagaa gttcctgccg aatcgtcttc
     1681 gtcacccccg gggtccgagg tagcctccct tacacagcct gagaagagca caggccgagt
     1741 gcccacccag gagcccaccc acagggagcc caccaggcaa gcagcctccc aagagtccga
     1801 ggaggccggg ggcaccggcg ggcccccggc aggcgtgcga tctatcatga aacggaaaga
     1861 ggaggttgca gaccccacgg cccaccggag gagcctccag ttcgtggggg tcaacggcgg
     1921 gtatgagtcg tcatccgagg actccagcac agcagagaac atctcagaca acgacagcac
     1981 agagaacgag gccccagagc cgagggagag ggttccgagt gtggccgaag ccccccagct
     2041 caggcctgca gggacggcag cggccaagac cagccggcag gagtgtcagc tgtctcgaga
     2101 atctcagcac atacccactg ctgagggggc atcaggatca aacacggagg aggagatcag
     2161 gatggagcta agccctgacc tcatctcagc ctgcttggcc ctggaaaagt acctggacaa
     2221 tcccaacgcc ctcacagagc gggagctgaa agtggcctac accacagtgc tgcaggagtg
     2281 gctgcgcctg gcctgccgca gcgacgcaca ccccgagctg gtgcggcggc acctggtcac
     2341 gttccgggcc atgtctgcgc ggctgctgga ctacgtggtc aacatcgccg acagcaacgg
     2401 caacacagcc ctgcactact ccgtgtctca tgccaacttc cccgtggtgc agcagctgct
     2461 cgacagcggt gtctgcaagg tggacaaaca gaaccgtgct ggctacagcc ctattatgct
     2521 caccgccctg gccaccctga agacccagga cgacatcgag actgtccttc agctcttccg
     2581 gcttggcaac atcaatgcca aagccagcca ggcaggacag acggccctga tgctggccgt
     2641 cagccacggg cgggtggacg ttgtcaaagc cctgctggcc tgtgaggcag atgtcaacgt
     2701 gcaagatgat gacggctcca cggccctcat gtgcgcctgt gagcacggcc acaaggagat
     2761 cgcggggctg ctgctggccg tgcccagctg tgacatctca ctcacagatc gcgatgggag
     2821 cacagctctg atggtggcct tggacgcagg gcagagtgag attgcgtcca tgctgtattc
     2881 ccgcatgaac atcaagtgct cgtttgcccc aatgtcagat gacgagagcc ctacatcatc
     2941 ctcggcagaa gagtagccgt gagggaggcg gggaccagcc agaccgggag caaaccgtcc
     3001 cttgtccccg tctcctccct gttcccgttc ctccctggcc caccccactc acactcccca
     3061 aggcccacgg ctcaaaggca agcgagctct ccctctgctt ccctggggga gccccgacgg
     3121 ccacaggact ccagctccaa gtgggttttc ttggctcccc tgttcaaagt ggccacagcg
     3181 cagaccgaag caaaattctt gtatacattg gcgccagggc tgatgctggg gtgtgggttt
     3241 tatgaagaac attgagaaca atcagctggt aattatggat ggaggaagag ggagaggaaa
     3301 aaaatattgt atttttgaat cattgttgca ggagggggtg ggaatcttag gatttgttgc
     3361 cagatttgaa agtcactgga acttgcatat tttcatttta atcctaagtg ttattacgca
     3421 ccagttgggg ttcacccttc atcccccaca tttaattgtc tgatatagaa tagtgttgtg
     3481 tccactgccc cgctagacgg ctttcttagg ggaattttct tctggttgtt tcacaagaca
     3541 gattctgtcc ttgtcacccg ggacagaaaa ctcagtcttt tcaccctcat tcagatgaag
     3601 ggactcagga caggctctgt gacttacagg gacccaatca attcacaatg agaaattacc
     3661 ggccaggcgt ggtgactcac gtctgtaatc ccagcacttt gggagggcaa ggcaagagct
     3721 tgagcttgag cctagacgtt aaagaccagc ctgggcaaca cagcaagacc catctctaca
     3781 agaaatttaa aaactagcca ggcgtggtgg tgcgcgcctg tagtcccagc tacttgggag
     3841 gctgagccct ggaggtcgag gctacagtga gctatgatca caccattgca cttcagcctg
     3901 ggcgacacag cgagaccctg tctcaagaaa gaaaagaaaa agagacaaat tacccagaaa
     3961 cccctccctt ccccacatgg aggccttggc aaatgttaat tttcctagaa aatccttcag
     4021 acctgaagac gcaggaaaag aatctggctc tcagggtggc ttctgcgtcc ccgccgccag
     4081 gccccagact atggtcacag ggccgtcctg ttcctccccg ggactccaga atttctctcc
     4141 tcaaaggaaa gaaaacaggg catgcgcttg ttggcaaaac gcagggccgg ctcccaaaaa
     4201 ccccatgtgt gtacgattaa aagttggccg tccccaggcc tcccagcgca aacttcaaga
     4261 gacagggctt tgctgaaaac caaacatggg ccagctgggc tttttaacaa cctagagact
     4321 ttccggagct gcctggaaca gagcctgcgg gaaacggggc ttgccagaga cactcacagt
     4381 ttccttcatg gcctgttttg gtcccctaag aatctccaca tcattgtctt tcttgtgcct
     4441 tttccttggt gagcaacaga aagggaaggg ttccaagcct ctaaaaatgt gctttgtgat
     4501 caggagtgcg ctccaaacca aatacgcgcg ctgccctttc gaggccagtg agctcagcct
     4561 ccaaggcttt aaagccacat ttcagcaaga gaaagcgctg agagctcgca ggttcattaa
     4621 agaaggcaaa gcactggttt ctctccttag aaaagtaggt ttcttggctt gatgtagact
     4681 ggcttgcttt gatttttagt gaagggaatg tacgtaaaac aaaatagggc ttggctggtc
     4741 aaaggagaca agcaggatgg atggatggat ggatggatgg atggatggat ggatggatgg
     4801 atgaatagat agatggtgtt tgcatgtaaa ttgcagagaa aacaaaacca aagctgattg
     4861 gaaacaatta attgtgggtg tctgaggggg aaggtcgcag ctttgggcag ctttgagaag
     4921 cggtacaaga gttctgtgcc tgtgtgtcca gccctggagc cagccagtgc atttatttta
     4981 agctcttaga agcaactcct tggcccagga atgcgtgacc cctgagatgg gtccacgcat
     5041 ctctctacac ttccttctct ccgtgggata ctggactcgt gcctctgcgc ccattctctt
     5101 ctcacgcata tccatgagct ttaatttcac tttctgatca cggtacgtcc ataaagccag
     5161 tattacactt aaatgaagta ttcttttttg taatcgtttt ttttagaagg taaacaaatt
     5221 taataaagct accaataatg ttga
//
