LOCUS       XM_047431353            5042 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens jagged canonical Notch ligand 2 (JAG2),
            transcript variant X2, mRNA.
ACCESSION   XM_047431353
VERSION     XM_047431353.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000014.9) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5042
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
     gene            1..5042
                     /gene="JAG2"
                     /gene_synonym="HJ2; LGMDR27; SER2"
                     /note="jagged canonical Notch ligand 2; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 30 ESTs, 237 long SRA reads, 3 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 7 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:3714"
                     /db_xref="HGNC:HGNC:6189"
                     /db_xref="MIM:602570"
     CDS             82..3342
                     /gene="JAG2"
                     /gene_synonym="HJ2; LGMDR27; SER2"
                     /codon_start=1
                     /product="protein jagged-2 isoform X2"
                     /protein_id="XP_047287309.1"
                     /db_xref="GeneID:3714"
                     /db_xref="HGNC:HGNC:6189"
                     /db_xref="MIM:602570"
                     /translation="MVTQDRSETEIVDPGAVTFCGTALFRSFTLIVEAWDWDNDTTPN
                     EELLIERVSHAGMINPEDRWKSLHFSGHVAHLELQIRVRCDENYYSATCNKFCRPRND
                     FFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCD
                     ECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYR
                     CTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECA
                     SNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQCQHGGTCKDLVNGYQCVC
                     PRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSP
                     CRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAA
                     SGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRC
                     FCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDA
                     YTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCI
                     CRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSS
                     PCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSC
                     RCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCPLGQRCLEKAPGQCLRPPCEAWGECG
                     AEEPPSTPCLPRSGHLDNNCARLTLHFNRDHVPQGTTVGAICSGIRSLPATRAVARDR
                     LLVLLCDRASSGASAVEVAVSFSPARDLPDSSLIQGAAHAIVAAITQRGNSSLLLAVT
                     EVKVETVVTGGSSTGLLVPVLCGAFSVLWLACVVLCVWWTRKRRKERERSRLPREESA
                     NNQWAPLNPIRNPIERPGGHKDVLYQCKNFTPPPRRADEALPGPAGHAAVREDEEDED
                     LGRGEEDSLEAEKFLSHKFTKDPGRSPGRPAHWASGPKVDNRAVRSINEARYAGKE"
ORIGIN      
        1 cctggggggc acgggcgggc gccgtgggac ctaggcccgg gagagcctaa cgcctaacgc
       61 ttatgtcggc agaagccccc gatggtgacc caagatcgtt cagagacaga gatagtggat
      121 cctggtgcag tgaccttctg tggcactgcc ctgtttcgct cctttaccct catcgtggag
      181 gcctgggact gggacaacga taccaccccg aatgaggagc tgctgatcga gcgagtgtcg
      241 catgccggca tgatcaaccc ggaggaccgc tggaagagcc tgcacttcag cggccacgtg
      301 gcgcacctgg agctgcagat ccgcgtgcgc tgcgacgaga actactacag cgccacttgc
      361 aacaagttct gccggccccg caacgacttt ttcggccact acacctgcga ccagtacggc
      421 aacaaggcct gcatggacgg ctggatgggc aaggagtgca aggaagctgt gtgtaaacaa
      481 gggtgtaatt tgctccacgg gggatgcacc gtgcctgggg agtgcaggtg cagctacggc
      541 tggcaaggga ggttctgcga tgagtgtgtc ccctaccccg gctgcgtgca tggcagttgt
      601 gtggagccct ggcagtgcaa ctgtgagacc aactggggcg gcctgctctg tgacaaagac
      661 ctgaactact gtggcagcca ccacccctgc accaacggag gcacgtgcat caacgccgag
      721 cctgaccagt accgctgcac ctgccctgac ggctactcgg gcaggaactg tgagaaggct
      781 gagcacgcct gcacctccaa cccgtgtgcc aacgggggct cttgccatga ggtgccgtcc
      841 ggcttcgaat gccactgccc atcgggctgg agcgggccca cctgtgccct tgacatcgat
      901 gagtgtgctt cgaacccgtg tgcggccggt ggcacctgtg tggaccaggt ggacggcttt
      961 gagtgcatct gccccgagca gtgggtgggg gccacctgcc agctggacgt caacgactgt
     1021 cgcgggcagt gtcagcatgg gggcacctgc aaggacctgg tgaacgggta ccagtgtgtg
     1081 tgcccacggg gcttcggagg ccggcattgc gagctggaac gagacgagtg tgccagcagc
     1141 ccctgccaca gcggcggcct ctgcgaggac ctggccgacg gcttccactg ccactgcccc
     1201 cagggcttct ccgggcctct ctgtgaggtg gatgtcgacc tttgtgagcc aagcccctgc
     1261 cggaacggcg ctcgctgcta taacctggag ggtgactatt actgcgcctg ccctgatgac
     1321 tttggtggca agaactgctc cgtgccccgc gagccgtgcc ctggcggggc ctgcagagtg
     1381 atcgatggct gcgggtcaga cgcggggcct gggatgcctg gcacagcagc ctccggcgtg
     1441 tgtggccccc atggacgctg cgtcagccag ccagggggca acttttcctg catctgtgac
     1501 agtggcttta ctggcaccta ctgccatgag aacattgacg actgcctggg ccagccctgc
     1561 cgcaatgggg gcacatgcat cgatgaggtg gacgccttcc gctgcttctg ccccagcggc
     1621 tgggagggcg agctctgcga caccaatccc aacgactgcc ttcccgatcc ctgccacagc
     1681 cgcggccgct gctacgacct ggtcaatgac ttctactgtg cgtgcgacga cggctggaag
     1741 ggcaagacct gccactcacg cgagttccag tgcgatgcct acacctgcag caacggtggc
     1801 acctgctacg acagcggcga caccttccgc tgcgcctgcc cccccggctg gaagggcagc
     1861 acctgcgccg tcgccaagaa cagcagctgc ctgcccaacc cctgtgtgaa tggtggcacc
     1921 tgcgtgggca gcggggcctc cttctcctgc atctgccggg acggctggga gggtcgtact
     1981 tgcactcaca ataccaacga ctgcaaccct ctgccttgct acaatggtgg catctgtgtt
     2041 gacggcgtca actggttccg ctgcgagtgt gcacctggct tcgcggggcc tgactgccgc
     2101 atcaacatcg acgagtgcca gtcctcgccc tgtgcctacg gggccacgtg tgtggatgag
     2161 atcaacgggt atcgctgtag ctgcccaccc ggccgagccg gcccccggtg ccaggaagtg
     2221 atcgggttcg ggagatcctg ctggtcccgg ggcactccgt tcccacacgg aagctcctgg
     2281 gtggaagact gcaacagctg ccgctgcctg gatggccgcc gtgactgcag caaggtgtgg
     2341 tgcggatgga agccttgtct gctggccggc cagcccgagg ccctgagcgc ccagtgccca
     2401 ctggggcaaa ggtgcctgga gaaggcccca ggccagtgtc tgcgaccacc ctgtgaggcc
     2461 tggggggagt gcggcgcaga agagccaccg agcaccccct gcctgccacg ctccggccac
     2521 ctggacaata actgtgcccg cctcaccttg catttcaacc gtgaccacgt gccccagggc
     2581 accacggtgg gcgccatttg ctccgggatc cgctccctgc cagccacaag ggctgtggca
     2641 cgggaccgcc tgctggtgtt gctttgcgac cgggcgtcct cgggggccag tgctgtggag
     2701 gtggccgtgt ccttcagccc tgccagggac ctgcctgaca gcagcctgat ccagggcgcg
     2761 gcccacgcca tcgtggccgc catcacccag cgggggaaca gctcactgct cctggctgtc
     2821 accgaggtca aggtggagac ggttgttacg ggcggctctt ccacaggtct gctggtgcct
     2881 gtgctgtgtg gtgccttcag cgtgctgtgg ctggcgtgcg tggtcctgtg cgtgtggtgg
     2941 acacgcaagc gcaggaaaga gcgggagagg agccggctgc cgcgggagga gagcgccaac
     3001 aaccagtggg ccccgctcaa ccccatccgc aaccccattg agcggccggg gggccacaag
     3061 gacgtgctct accagtgcaa gaacttcacg ccgccgccgc gcagggcgga cgaggcgctg
     3121 cccgggccgg ccggccacgc ggccgtcagg gaggatgagg aggacgagga tctgggccgc
     3181 ggtgaggagg actccctgga ggcggagaag ttcctctcac acaaattcac caaagatcct
     3241 ggccgctcgc cggggaggcc ggcccactgg gcctcaggcc ccaaagtgga caaccgcgcg
     3301 gtcaggagca tcaatgaggc ccgctacgcc ggcaaggagt aggggcggct gccagctggg
     3361 ccgggaccca gggccctcgg tgggagccat gccgtctgcc ggacccggag gccgaggcca
     3421 tgtgcatagt ttctttattt tgtgtaaaaa aaccaccaaa aacaaaaacc aaatgtttat
     3481 tttctacgtt tctttaacct tgtataaatt attcagtaac tgtcaggctg aaaacaatgg
     3541 agtattctcg gatagttgct atttttgtaa agtttccgtg cgtggcactc gctgtatgaa
     3601 aggagagagc aaagggtgtc tgcgtcgtca ccaaatcgta gcgtttgtta ccagaggttg
     3661 tgcactgttt acagaatctt ccttttattc ctcactcggg tttctctgtg gctccaggcc
     3721 aaagtgccgg tgagacccat ggctgtgttg gtgtggccca tggctgttgg tgggacccgt
     3781 ggctgatggt gtggcctgtg gctgtcggtg ggactcgtgg ctgtcaatgg gacctgtggc
     3841 tgtcggtggg acctacggtg gtcggtggga ccctggttat tgatgtggcc ctggctgccg
     3901 gcacggcccg tggctgttga cgcacctgtg gttgttagtg gggcctgagg tcatcggcgt
     3961 ggcccaaggc tggcaggtca acctcgcgct tgctggccag tccaccctgc ctgccgtctg
     4021 tgcttcctcc tgcccagaac gcccgctcca gcgatctctc cactgtgctt tcagaagtgc
     4081 ccttcctgct gcgcagttct cccatcctgg gacggcggca gtattgaagc tcgtgacaag
     4141 tgccttcaca cagacccctc gcaactgtcc acgcgtgccg tggcaccagg cgctgcccac
     4201 ctgccggccc cggccgcccc tcctcgtgaa agtgcatttt tgtaaatgtg tacatattaa
     4261 aggaagcact ctgtatattt gattgaataa tgccaccatt ccggcctccc ttgttctttc
     4321 ggtgctgtcc cttttgtatt gagagtgagg ttgggggaga gccacgccgg cagagaggct
     4381 tggggcagtg gggcgcgtgc tgggtattgg cccacgtggc tgtggtggct gtagagggcg
     4441 agacggttct gttgagtcgg ggcctgccag ggcctcgaat gcgttggcat gccaaggtgg
     4501 tggatgcagg tttggccaaa accttcctgg gaatggggag gggggtgtct aggtgcctgg
     4561 cacccgaccc tgactaaaac agctgaaaac agttttataa aatagtataa aattgcttac
     4621 ccacgaatac gtatcaaggt cttaaggaat taacaggtca aaatttttat tcattcattt
     4681 attcctttgt tttgcttggt cattcagagg caaggtcagc atttgatgga ggcaggagag
     4741 aagcagccct tccacctggc cctggagctg gttttgcccc tcactgcttg agccaactgg
     4801 aacgtggcat ggtggcctca gggctgggca tggaaggccg actccaaggc tgactccgag
     4861 ccgcctgtca gtgatgtgca agtctttacc ctgctgtgag gggtaggagg tcaactgagt
     4921 caaggagcaa agccaagaac cagatctgta caaaagagaa aaaaaaagtc ctgctgacag
     4981 cctgggagtg aggctgcctt gcacaggcag aacaaatgaa taaatgaatg aacgaataaa
     5041 aa
//
