LOCUS       XM_017022155            3387 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens isovaleryl-CoA dehydrogenase (IVD),
            transcript variant X8, mRNA.
ACCESSION   XM_017022155
VERSION     XM_017022155.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000015.10) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017022155.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3387
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
     gene            1..3387
                     /gene="IVD"
                     /gene_synonym="ACAD2; IVDH"
                     /note="isovaleryl-CoA dehydrogenase; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 25
                     ESTs, 326 long SRA reads, and 78% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     26 samples with support for all annotated introns"
                     /db_xref="GeneID:3712"
                     /db_xref="HGNC:HGNC:6186"
                     /db_xref="MIM:607036"
     CDS             25..1281
                     /gene="IVD"
                     /gene_synonym="ACAD2; IVDH"
                     /codon_start=1
                     /product="isovaleryl-CoA dehydrogenase, mitochondrial
                     isoform X6"
                     /protein_id="XP_016877644.1"
                     /db_xref="GeneID:3712"
                     /db_xref="HGNC:HGNC:6186"
                     /db_xref="MIM:607036"
                     /translation="MAEMATATRLLGWRVASWRLRPPLAGFVSQRAHSLLPVDDAING
                     LSEEQRQLRQTMAKFLQEHLAPKAQEIDRSNEFKNLRVSWEVRAVGGSQGVGLSCTAA
                     WKSSHSFLEFWKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGA
                     HSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMKLKAEKKGNH
                     YILNGNKFWITNGPDADVLIVYAKTDLAAVPASRGITAFIVEKGMPGFSTSKKLDKLG
                     MRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGLDLERLVLAGGPLGLMQAVLDHT
                     IPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTAKDCAGV
                     ILYSAECATQVALDGIQCFVSRGISS"
     polyA_site      3387
                     /gene="IVD"
                     /gene_synonym="ACAD2; IVDH"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 agtttcagcg ctggctcttc gtgcatggca gagatggcga ctgcgactcg gctgctgggg
       61 tggcgtgtgg cgagctggag gctgcggccg ccgcttgccg gcttcgtttc ccagcgggcc
      121 cactcgcttt tgcccgtgga cgatgcaatc aatgggctaa gcgaggagca gaggcagctt
      181 cgtcagacca tggctaagtt ccttcaggag cacctggccc ccaaggccca ggagatcgat
      241 cgcagcaatg agttcaagaa cctgcgagtg agttgggagg tccgggcagt cgggggcagt
      301 cagggagtgg ggctgagctg cactgctgcc tggaagagct cacacagttt tctggaattt
      361 tggaagcagc tggggaacct gggcgtattg ggcatcacag cccctgttca gtatggcggc
      421 tccggcctgg gctacctgga gcatgtgctg gtgatggagg agatatcccg agcttccgga
      481 gcagtggggc tcagttacgg tgcccactcc aacctctgca tcaaccagct tgtacgcaat
      541 gggaatgagg cccagaaaga gaagtatctc ccgaagctga tcagtggtga gtacatcgga
      601 gccctggcca tgagtgagcc caatgcaggc tctgatgttg tctctatgaa gctcaaagcg
      661 gaaaagaaag gaaatcacta catcctgaat ggcaacaagt tctggatcac taatggccct
      721 gatgctgacg tcctgattgt ctatgccaag acagatctgg ctgctgtgcc agcttctcgg
      781 ggcatcacag ccttcattgt ggagaagggt atgcctggct ttagcacctc taagaagctg
      841 gacaagctgg ggatgagggg ctctaacacc tgtgagctaa tctttgaaga ctgcaagatt
      901 cctgctgcca acatcctggg ccatgagaat aagggtgtct acgtgctgat gagtgggctg
      961 gacctggagc ggctggtgct ggccgggggg cctcttgggc tcatgcaagc ggtcctggac
     1021 cacaccattc cctacctgca cgtgagggaa gcctttggcc agaagatcgg ccacttccag
     1081 ttgatgcagg ggaagatggc tgacatgtac acccgcctca tggcgtgtcg gcagtatgtc
     1141 tacaatgtcg ccaaggcctg cgatgagggc cattgcactg ctaaggactg tgcaggtgtg
     1201 attctttact cagctgagtg tgccacacag gtagccctgg acggcattca gtgttttgtt
     1261 tctagaggta tcagctccta gcagcttatg aacacatatg cttgcttggc caggcaaggt
     1321 ggtgtgtgcc tgtaatccca gcactttggg aggccaaggc aggtggatca cttgcagtca
     1381 ggagttcaag accagcctgt ccaacgtggt gaaaccccat ctctactaaa aatacaaaaa
     1441 ttagccaggg gtggtggtgc acgtctgtaa tcccagctac tcaggaggct gaggcaggag
     1501 aatcacttga acccgggagg tggaggttgc aatgagccaa tatgacaccg ctgcagtcca
     1561 gcctgggcca tagagtgaga ctctgtctca aaaaaggaaa gaaaaatagg ctgggcacag
     1621 tgactcatgc ctgtaatccc aacactttgg gaggccgagg caggtggatc acgaggtcag
     1681 gagttcaaga ccagcctggc caagatggta aaacctcgtc tctactaaaa atacaaaaat
     1741 tagccaggtg tggtggcagg ctcctgtaat cccagctact caggaggctg aggcagagaa
     1801 ttgcttgaac ccgggaggca gagtttgcag tgagccaaga tcacaccact gcactccagc
     1861 ttggacgaca gagcgagact ctgtctcaaa aaataatagg ccaggcatgg tggctcaacg
     1921 tctgtaatcc cagcactttg ggaggccgag gcgggcagat cacaaggtca ggagttcgag
     1981 accagcctga cgaccaacat ggtgaaacct cgtctctact aaaaatacaa aaattagcca
     2041 ggcctggtgg cacgcgcctg taatcccagt tacacagaag actgaggcag gagaatcgct
     2101 tgaacgcagg aggcagaggt tgcaggagct gagatcgcgc cattgcactc cagcctgggc
     2161 aacagagtga gactctgtct caaaaaataa taataaaata aatgaacaca catgctgctg
     2221 agtccgcagg gggggcagag cagaggacag cgtgcttttg tgtactgttg gaagactggc
     2281 tcctcctgta cagcacctct gagcccttgt gcaccgccct gccacgggca ccatccagtc
     2341 ctggccgtgt gaccacccac agctgactgg gcagcaggca caggccctac ccgagcaggc
     2401 cggagttggc tcgcatgact ccagctgagg ctgcctgtgt acatttctcc agatacccta
     2461 tggctaattt tgttataact gcacagtggc tgctgccatt ttgtattaaa tatattgtga
     2521 aacaaaccta tctggggaga agcaatctac ttgccgctgc ttcctgtctg gatccagctt
     2581 gtgtccttgg agagtggctg gcccaggtcc tattcctgtc ctccagcccg ttctttcatg
     2641 agggacagga aggtaaaatc agcccttagg agagaggtct cagcctccct ttcccagatc
     2701 tcccagtgag ttttaaagga agcagggagc ccagagtgct aagttcttac agccagaagg
     2761 aagcttatag atttctgaaa accgcccctt tgtttttaaa aagatcaaca caatttgact
     2821 ttctcaaggt caaaacgaac tagaatccag atctgctcat ggcaaaaatg ggggtgttct
     2881 gagaattcca gctttgggcc gcactgtaca gcagtctgga tagagtgtga tctgagaagg
     2941 gaatgggtct gggttgttcc accccttccg agttccaaaa agagggaact ggttttcttg
     3001 gttctcagcc cagcagcacc tatcctggct cttggtcctg gcctgcagcc aagtgctgtt
     3061 cctagcctga ggcttgagac aggtggggtt ggctcctcac caaccccagt tccgtcccat
     3121 cctgagggca agatcctggg ctcataggca gtccctttca cttccttgtc ttgctccctg
     3181 ctatgttgga gatgaatgtg actaaaaggg ccatcttgct ggcttaatgt gtggctggag
     3241 agaccagcct ggagacaatg tggcaaaatg gggcgcttca tccagtctgt ctaagccctg
     3301 tcgacttggg gaggtgattt ctttcctggt tctatatgtg aagcaaaata aatgttttaa
     3361 aattaaaagc aaaaaaaaca aaatgaa
//
