LOCUS       XM_017022149            1789 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens isovaleryl-CoA dehydrogenase (IVD),
            transcript variant X1, mRNA.
ACCESSION   XM_017022149
VERSION     XM_017022149.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000015.10) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017022149.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1789
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
     gene            1..1789
                     /gene="IVD"
                     /gene_synonym="ACAD2; IVDH"
                     /note="isovaleryl-CoA dehydrogenase; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 21
                     ESTs, 96 long SRA reads, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     44 samples with support for all annotated introns"
                     /db_xref="GeneID:3712"
                     /db_xref="HGNC:HGNC:6186"
                     /db_xref="MIM:607036"
     CDS             25..1575
                     /gene="IVD"
                     /gene_synonym="ACAD2; IVDH"
                     /codon_start=1
                     /product="isovaleryl-CoA dehydrogenase, mitochondrial
                     isoform X1"
                     /protein_id="XP_016877638.1"
                     /db_xref="GeneID:3712"
                     /db_xref="HGNC:HGNC:6186"
                     /db_xref="MIM:607036"
                     /translation="MAEMATATRLLGWRVASWRLRPPLAGFVSQRAHSLLPVDDAING
                     LSEEQRQLRQTMAKFLQEHLAPKAQEIDRSNEFKNLRVSWEVRAVGGSQGVGLSCTAA
                     WKSSHSFLEFWKQLGNLGVLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGA
                     HSNLCINQLVRNGNEAQKEKYLPKLISGEYIGALAMSEPNAGSDVVSMKLKAEKKGNH
                     YILNGNKFWITNGPDADVLIVYAKTDLAAVPASRGITAFIVEKGMPGFSTSKKLDKLG
                     MRGSNTCELIFEDCKIPAANILGHENKGVYVLMSGLDLERLVLAGGPLGLMQAVLDHT
                     IPYLHVREAFGQKIGHFQLMQGKMADMYTRLMACRQYVYNVAKACDEGHCTAKDCAGV
                     ILYSAECATQVALDGIQCFGQTFSAQHPPGREGETRGQTSLEQVSTARELRCKILLPE
                     LTPRVLLPQLASWISDQKLPFLKILLCSPTSLGQSSLAGFTKLRWPYPLLQPHLLPHP
                     YTTALHLC"
ORIGIN      
        1 agtttcagcg ctggctcttc gtgcatggca gagatggcga ctgcgactcg gctgctgggg
       61 tggcgtgtgg cgagctggag gctgcggccg ccgcttgccg gcttcgtttc ccagcgggcc
      121 cactcgcttt tgcccgtgga cgatgcaatc aatgggctaa gcgaggagca gaggcagctt
      181 cgtcagacca tggctaagtt ccttcaggag cacctggccc ccaaggccca ggagatcgat
      241 cgcagcaatg agttcaagaa cctgcgagtg agttgggagg tccgggcagt cgggggcagt
      301 cagggagtgg ggctgagctg cactgctgcc tggaagagct cacacagttt tctggaattt
      361 tggaagcagc tggggaacct gggcgtattg ggcatcacag cccctgttca gtatggcggc
      421 tccggcctgg gctacctgga gcatgtgctg gtgatggagg agatatcccg agcttccgga
      481 gcagtggggc tcagttacgg tgcccactcc aacctctgca tcaaccagct tgtacgcaat
      541 gggaatgagg cccagaaaga gaagtatctc ccgaagctga tcagtggtga gtacatcgga
      601 gccctggcca tgagtgagcc caatgcaggc tctgatgttg tctctatgaa gctcaaagcg
      661 gaaaagaaag gaaatcacta catcctgaat ggcaacaagt tctggatcac taatggccct
      721 gatgctgacg tcctgattgt ctatgccaag acagatctgg ctgctgtgcc agcttctcgg
      781 ggcatcacag ccttcattgt ggagaagggt atgcctggct ttagcacctc taagaagctg
      841 gacaagctgg ggatgagggg ctctaacacc tgtgagctaa tctttgaaga ctgcaagatt
      901 cctgctgcca acatcctggg ccatgagaat aagggtgtct acgtgctgat gagtgggctg
      961 gacctggagc ggctggtgct ggccgggggg cctcttgggc tcatgcaagc ggtcctggac
     1021 cacaccattc cctacctgca cgtgagggaa gcctttggcc agaagatcgg ccacttccag
     1081 ttgatgcagg ggaagatggc tgacatgtac acccgcctca tggcgtgtcg gcagtatgtc
     1141 tacaatgtcg ccaaggcctg cgatgagggc cattgcactg ctaaggactg tgcaggtgtg
     1201 attctttact cagctgagtg tgccacacag gtagccctgg acggcattca gtgttttggg
     1261 cagacctttt ccgcccaaca cccacctggg agggagggcg agacccgagg tcagacgtcc
     1321 ctggagcagg tgagcactgc gagggaactg agatgcaaga tcctcctgcc tgaactcaca
     1381 ccccgcgtgc tgctccccca actcgcctct tggatctcag accagaagct tcctttcctc
     1441 aaaatccttc tatgttctcc aacgtctttg ggacagagct ccttggcagg gtttacaaag
     1501 cttaggtggc cctacccact tctccagcct catctgctgc ctcaccccta taccacagct
     1561 ctgcaccttt gctgaaactg gtactcggcg cttggggtgt cctcatcttt cccctaccta
     1621 tggcagcctg cccgaagagt gcctgctcct tcaggctccg ctctcggctt agccccttct
     1681 tggaacgtcc ccgcacctca ccccagcccc ttgccagggg cagaccctgg cagccttccc
     1741 tcgtcctcag cagccattac gtgttgctgt cataaagtta tcactctgt
//
