LOCUS       XM_017010832            4100 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens inositol 1,4,5-trisphosphate receptor type
            3 (ITPR3), transcript variant X5, mRNA.
ACCESSION   XM_017010832
VERSION     XM_017010832.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000006.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017010832.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4100
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
     gene            1..4100
                     /gene="ITPR3"
                     /gene_synonym="CMT1J; IP3R; IP3R-3; IP3R3"
                     /note="inositol 1,4,5-trisphosphate receptor type 3;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 29 ESTs, 49 long SRA reads, 2 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 23 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:3710"
                     /db_xref="HGNC:HGNC:6182"
                     /db_xref="MIM:147267"
     CDS             65..4003
                     /gene="ITPR3"
                     /gene_synonym="CMT1J; IP3R; IP3R-3; IP3R3"
                     /codon_start=1
                     /product="inositol 1,4,5-trisphosphate-gated calcium
                     channel ITPR3 isoform X3"
                     /protein_id="XP_016866321.1"
                     /db_xref="GeneID:3710"
                     /db_xref="HGNC:HGNC:6182"
                     /db_xref="MIM:147267"
                     /translation="MSEMSSFLHIGDIVSLYAEGSVNGFISTLGLVDDRCVVEPAAGD
                     LDNPPKKFRDCLFKVCPMNRYSAQKQYWKAKQTKQDKEKIADVVLLQKLQHAAQMEQK
                     QNDTENKKVHGDVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGS
                     WLFIQPFWKLRSNGDNVVVGDKVILNPVNAGQPLHASNYELSDNAGCKEVNSVNCNTS
                     WKINLFMQFRDHLEEVLKGGDVVRLFHAEQEKFLTCDEYKGKLQVFLRTTLRQSATSA
                     TSSNALWEVEVVHHDPCRGGAGHWNGLYRFKHLATGNYLAAEENPSYKGDASDPKAAG
                     MGAQGRTGRRNAGEKIKYCLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRLRHL
                     CTNTWIQSTNVPIDIEEERPIRLMLGTCPTKEDKEAFAIVSVPVSEIRDLDFANDASS
                     MLASAVEKLNEGFISQNDRRFVIQLLEDLVFFVSDVPNNGQNVLDIMVTKPNRERQKL
                     MREQNILKQVFGILKAPFREKGGEGPLVRLEELSDQKNAPYQHMFRLCYRVLRHSQED
                     YRKNQEHIAKQFGMMQSQIGYDILAEDTITALLHNNRKLLEKHITKTEVETFVSLVRK
                     NREPRFLDYLSDLCVSNHIAIPVTQELICKCVLDPKNSDILIRTELRPVKEMAQSHEY
                     LSIEYSEEEVWLTWTDKNNEHHEKSVRQLAQEARAGNAHDENVLSYYRYQLKLFARMC
                     LDRQYLAIDEISQQLGVDLIFLCMADEMLPFDLRASFCHLMLHVHVDRDPQELVTPVK
                     FARLWTEIPTAITIKDYDSNLNASRDDKKNKFANTMEFVEDYLNNVVSEAVPFANEEK
                     NKLTFEVVSLAHNLIYFGFYSFSELLRLTRTLLGIIDCVQGPPAMLQAYEDPGGKNVR
                     RSIQGVGHMMSTMVLSRKQSVFSAPSLSAGASAAEPLDRSKFEENEDIVVMETKLKIL
                     EILQFILNVRLDYRISYLLSVFKKEFVEVFPMQDSGADGTAPAFDSTTANMNLDRIGE
                     QAEAMFGVGKTSSMLEVDDEGGRMFLRVLIHLTMHDYAPLVSGALQLLFKHFSQRQEA
                     MHTFKQVQLLISAQDVENYKVIKSELDRLRTMVEKSELWVDKKGSGKGEEVEAGAAKD
                     KKERPTDEEGFLHPPGEKSSENYQIVKGILERLNKMCGVGEQMRKKQQRLLKNMDAHK
                     VMLDLLQIPYDKGDAKMMEILRYTHQFLQKFCAGNPGNQALLHKHLHLFLTPGLLEAE
                     TMQHIFLNNYQLCSEISEPVLQHFVHLLATHGRHVQYLDFLHTVIKAEGN"
ORIGIN      
        1 agacttcctg ctccttctac gctgcaggcg ccccccacgc cctgggcccc ggagggccgc
       61 agccatgagt gaaatgtcca gctttcttca catcggggac atcgtctccc tgtacgccga
      121 gggctccgtc aatggcttca tcagcacttt ggggctggtg gatgaccgct gtgtggtgga
      181 gcccgcggcc ggggacctgg acaacccccc taagaagttc cgtgactgcc tcttcaaggt
      241 gtgccccatg aaccgctact cggcccagaa gcagtactgg aaggccaagc agactaagca
      301 ggacaaggag aagatcgctg atgtggtgtt gctgcagaag ctgcagcatg cggcgcagat
      361 ggagcagaag caaaatgaca cggagaacaa gaaggtgcat ggggatgtcg tgaagtatgg
      421 cagtgtgatc cagctcctgc acatgaagag caacaagtac ctgacagtga acaagcggct
      481 tccggccttg ctggagaaga acgccatgcg ggtgactctg gatgccacag gcaacgaggg
      541 ttcctggctc ttcatccagc ccttctggaa gctgcggagc aacggggaca acgtggtcgt
      601 gggggacaag gtgatcctga atcctgtcaa tgccgggcag cctctgcatg ccagcaatta
      661 cgagctcagc gacaacgccg gctgcaagga ggtcaattct gtgaactgca acaccagctg
      721 gaagatcaac ctgtttatgc agtttcggga ccacctggag gaggtgttga aagggggaga
      781 cgtggtgcgg ctgttccatg cggagcagga gaagttcctg acgtgtgacg agtacaaggg
      841 caagctgcag gtgttcctgc gaactacact gcgccagtct gccacctcgg ccaccagctc
      901 caatgctctc tgggaggtgg aggtggtcca ccacgacccc tgccgtggag gagctgggca
      961 ctggaatggc ttgtaccgct tcaagcacct ggctacaggc aactacctgg ctgctgagga
     1021 gaaccccagt tacaaaggtg atgcctcaga tcccaaggca gcaggaatgg gggcacaggg
     1081 ccgcacaggc cgcaggaatg ctggggagaa gatcaagtac tgcctggtgg ctgtgcctca
     1141 tggcaatgac atcgcctctc tctttgagct ggaccccacc accttgcaga aaaccgactc
     1201 tttcgtgccc cggaactcgt acgtccggct gcggcacctc tgcaccaaca cgtggattca
     1261 gagcaccaat gtgcccattg acatcgagga ggagcggccc atccggctca tgctgggcac
     1321 ctgccccacc aaggaggaca aggaggcctt tgccatcgtg tcagtgcccg tgtctgagat
     1381 ccgagacctg gactttgcca atgacgccag ctccatgctg gccagtgccg tggagaaact
     1441 caacgagggc ttcatcagcc agaatgaccg caggtttgtc atccagctgc tggaagacct
     1501 ggtgttcttt gtcagcgatg tccccaacaa tgggcagaat gtcctggaca tcatggtcac
     1561 taagcccaac cgggaacggc agaagctgat gagggagcag aacatcctca aacaggtctt
     1621 tggcattctg aaggccccgt tccgtgagaa ggggggtgaa ggtcccctgg tgcggctgga
     1681 ggagctgtca gaccagaaga acgcccccta ccagcacatg ttccgcctgt gctaccgcgt
     1741 gttgcggcat tcccaggagg actaccgcaa gaaccaggag cacattgcca agcagtttgg
     1801 gatgatgcag tcccagattg gctacgacat cctggccgag gacaccatca ctgccctgct
     1861 gcacaacaac cgcaagctcc tggaaaagca catcaccaag accgaggtgg agaccttcgt
     1921 cagccttgtg cgcaagaacc gggagcccag gttcctggac tacctctctg acctgtgtgt
     1981 gtccaaccac atcgccatcc ccgtcaccca agagctcatc tgcaagtgtg tgctggaccc
     2041 caagaacagt gacattctca tccggaccga gcttcggccc gtgaaggaga tggcccaatc
     2101 ccacgagtac ctgagcatcg agtactcaga agaggaagtg tggctcacgt ggactgacaa
     2161 gaataacgag catcatgaga agagtgtgag gcagctggcc caggaggcgc gggccggcaa
     2221 cgcccacgac gagaatgtgc tcagctacta caggtaccag ctgaagctct ttgcccgcat
     2281 gtgcttggac cgccagtact tggccatcga cgagatctcc cagcagctgg gcgtggacct
     2341 gattttcctg tgcatggcag acgagatgct gccctttgac ctgcgcgcct ccttctgcca
     2401 cctgatgctg cacgtgcacg tggaccgtga cccccaggag ctggtcacgc cggtcaagtt
     2461 tgcccgtctc tggactgaga tccccacagc catcaccatc aaggactatg attccaacct
     2521 caacgcgtcc cgagatgaca agaagaacaa gtttgccaac accatggagt tcgtggagga
     2581 ctacctcaac aatgtagtca gcgaggccgt gccctttgcc aacgaggaga agaacaagct
     2641 cacttttgag gtggtcagcc tggcgcacaa tctcatctac ttcggcttct acagcttcag
     2701 cgagctgctg cggctcactc gcacactgct gggcatcatc gactgtgtgc aggggccccc
     2761 ggccatgctg caggcctatg aggaccccgg tggcaagaat gtgcggcggt ccatccaggg
     2821 cgtggggcac atgatgtcca ccatggtgct gagccgcaag cagtccgtct tcagtgcccc
     2881 cagcctgtct gctggggcca gtgctgctga gccgctggac agaagcaagt ttgaggagaa
     2941 tgaggacatt gtggtgatgg agaccaagct gaagatcctg gaaatccttc agttcatcct
     3001 caatgtccgc ctggattacc gcatatccta cctgctgtct gtcttcaaga aggagtttgt
     3061 ggaggtgttt cccatgcagg acagtggggc tgatggcaca gcccctgcct tcgactctac
     3121 cactgccaac atgaacctgg atcgcatcgg ggagcaggcg gaggccatgt ttggagtggg
     3181 gaagacaagc agcatgctgg aggtggatga cgagggcggc cgcatgttcc tgcgcgtgct
     3241 catccacctc accatgcacg actatgcgcc gctggtctcg ggtgccctgc agctgctctt
     3301 caagcacttc agccagcgcc aggaggccat gcacaccttc aagcaggttc agctgctgat
     3361 ctcagcgcag gacgtggaga actacaaggt gatcaagtcg gagctggacc ggctgcggac
     3421 catggtggag aagtcagagc tgtgggtgga caagaagggc agtggcaagg gtgaggaggt
     3481 ggaggcaggc gccgccaagg acaagaaaga gcgtcccacg gacgaggagg gctttctgca
     3541 cccaccaggg gagaaaagca gtgagaacta ccagatcgtc aagggcatcc tggaaaggct
     3601 gaacaagatg tgcggggttg gggagcaaat gaggaagaag cagcaacggc tgctgaagaa
     3661 catggatgcc cacaaggtca tgctggacct gctgcagatc ccctatgaca agggtgatgc
     3721 caagatgatg gagatcctgc gctacacgca ccagttcctg cagaagttct gtgcagggaa
     3781 ccccggcaac caggccctgc tgcacaaaca cctgcacctc ttcctcacgc cagggctcct
     3841 ggaggcagag accatgcagc acatcttcct gaacaactat cagctctgct ccgagatcag
     3901 cgagcctgtg ttgcagcact tcgtgcacct gctggccacg cacgggcgcc atgtgcagta
     3961 cctggacttc ctgcacaccg tcattaaggc cgagggcaac tgaccaatgc aggtgacgat
     4021 gtggtcgtgt tctacaatga taaggcatcg ctggcccacc tgctggacat gatgaaggcc
     4081 gcccgcgacg gcgtggagga
//
