LOCUS       XM_017019269           18464 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens inositol 1,4,5-trisphosphate receptor type
            2 (ITPR2), transcript variant X5, mRNA.
ACCESSION   XM_017019269
VERSION     XM_017019269.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000012.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017019269.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18464
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
     gene            1..18464
                     /gene="ITPR2"
                     /gene_synonym="ANHD; CFAP48; INSP3R2; IP3R2"
                     /note="inositol 1,4,5-trisphosphate receptor type 2;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 13 ESTs, 795 long SRA reads, and 97%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 6 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:3709"
                     /db_xref="HGNC:HGNC:6181"
                     /db_xref="MIM:600144"
     CDS             414..5615
                     /gene="ITPR2"
                     /gene_synonym="ANHD; CFAP48; INSP3R2; IP3R2"
                     /codon_start=1
                     /product="inositol 1,4,5-trisphosphate-gated calcium
                     channel ITPR2 isoform X3"
                     /protein_id="XP_016874758.1"
                     /db_xref="GeneID:3709"
                     /db_xref="HGNC:HGNC:6181"
                     /db_xref="MIM:600144"
                     /translation="MTEKMSSFLYIGDIVSLYAEGSVNGFISTLGLVDDRCVVHPEAG
                     DLANPPKKFRDCLFKVCPMNRYSAQKQYWKAKQAKQGNHTEAALLKKLQHAAELEQKQ
                     NESENKKLLGEIVKYSNVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSW
                     FYIHPFWKLRSEGDNIVVGDKVVLMPVNAGQPLHASNIELLDNPGCKEVNAVNCNTSW
                     KITLFMKYSSYREDVLKGGDVVRLFHAEQEKFLTCDEYEKKQHIFLRTTLRQSATSAT
                     SSKALWEIEVVHHDPCRGGAGQWNSLFRFKHLATGNYLAAEMEGCSCFLIDCGTSMTF
                     TAQLNPDYRDAQNEGKNVRDGVPPTSKKKRQAGEKIMYTLVSVPHGNDIASLFELDAT
                     TLQRADCLVPRNSYVRLRHLCTNTWVTSTSIPIDTDEERPVMLKIGTCQTKEDKEAFA
                     IVSVPLSEVRDLDFANDANKVLATTVKKLENGTITQNERRFVTKLLEDLIFFVADVPN
                     NGQEVLDVVITKPNRERQKLMREQNILAQVFGILKAPFKEKAGEGSMLRLEDLGDQRY
                     APYKYMLRLCYRVLRHSQQDYRKNQEYIAKNFCVMQSQIGYDILAEDTITALLHNNRK
                     LLEKHITAKEIETFVSLLRRNREPRFLDYLSDLCVSNTTAIPVTQELICKFMLSPGNA
                     DILIQTKVVSMQADNPMESSILSDDIDDEEVWLYWIDSNKEPHGKAIRHLAQEAKEGT
                     KADLEVLTYYRYQLNLFARMCLDRQYLAINQISTQLSVDLILRCVSDESLPFDLRASF
                     CRLMLHMHVDRDPQESVVPVRYARLWTEIPTKITIHEYDSITDSSRNDMKRKFALTME
                     FVEEYLKEVVNQPFPFGDKEKNKLTFEVVHLARNLIYFGFYSFSELLRLTRTLLAILD
                     IVQAPMSSYFERLSKFQDGGNNVMRTIHGVGEMMTQMVLSRGSIFPMSVPDVPPSIHP
                     SKQGSPTEHEDVTVMDTKLKIIEILQFILSVRLDYRISYMLSIYKKEFGEDNDNAETS
                     ASGSPDTLLPSAIVPDIDEIAAQAETMFAGRKEKNPVQLDDEGGRTFLRVLIHLIMHD
                     YPPLLSGALQLLFKHFSQRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKS
                     ELWVEKSSNYENGEIGESQVKGGEEPIEESNILSPVQDGTKKPQIDSNKSNNYRIVKE
                     ILIRLSKLCVQNKKCRNQHQRLLKNMGAHSVVLDLLQIPYEKNDEKMNEVMNLAHTFL
                     QNFCRGNPQNQVLLHKHLNLFLTPGLLEAETMRHIFMNNYHLCNEISERVVQHFVHCI
                     ETHGRHVEYLRFLQTIVKADGKYVKKCQDMVMTELINGGEDVLIFYNDRASFPILLHM
                     MCSERDRGDESGPLAYHITLVELLAACTEGKNVYTEIKCNSLLPLDDIVRVVTHDDCI
                     PEVKIAYVNFVNHCYVDTEVEMKEIYTSNHIWKLFENFLVDMARVCNTTTDRKHADIF
                     LEKCVTESIMNIVSGFFNSPFSDNSTSLQTHQPVFIQLLQSAFRIYNCTWPNPAQKAS
                     VESCIRTLAEVAKNRGIAIPVDLDSQVNTLFMKSHSNMVQRAAMGWRLSARSGPRFKE
                     ALGGPAWDYRNIIEKLQDVVASLEHQFSPMMQAEFSVLVDVLYSPELLFPEGSDARIR
                     CGAFMSKLINHTKKLMEKEEKLCIKILQTLREMLEKKDSFVEEIKWSKENDCISVHAD
                     CLWHSAT"
ORIGIN      
        1 cagctcccgc cgggcggctg tgacggccgc agcgggtcgc agagcaggga gtggacacgg
       61 agtggggagc ggagagggaa ggaggaggag gaggagcaaa ggtgttggag agaaaacttc
      121 agaaaggaac aggaaacctg ccggggaggc ggcggcggct gcggcttctc tgggcgcctg
      181 ggctgcgctc ttcgcggggt gtccgcagct gcggcttggc cccggtctgg cttccccggc
      241 gcgcacgcac ggctgagccg cgacgctcag tggctcgggc cgtgccctcc gccgcggctc
      301 ttggccgctg tagtcccgcg atccgatccg cttctgccgc ggcggctccc tggagagagg
      361 gcggcgaggg cgcagggaag aagagggacg tccactgtgg aacatgaagc agcatgactg
      421 agaaaatgtc cagcttcctc tacatagggg acatcgtgtc cctgtacgcg gagggctcgg
      481 tcaacggctt catcagcacc ttggggttag tggatgacag atgtgtggtg cacccagagg
      541 ccggggacct tgccaaccct cccaagaagt tcagagactg ccttttcaag gtgtgcccta
      601 tgaacagata ttctgcccag aagcaatatt ggaaagcaaa gcaagccaaa caagggaacc
      661 acaccgaggc agccttgctg aagaaactac agcacgctgc agaactggaa caaaaacaaa
      721 atgaatcgga gaataagaaa ctgttgggag aaattgtaaa atacagtaat gttatacaac
      781 tactgcatat aaaaagcaac aaatatctta ctgtcaacaa gagattacct gctttactgg
      841 agaagaatgc catgcgtgtg tccttggatg ctgcaggaaa tgaagggtct tggttttata
      901 ttcatccgtt ctggaaactg agaagcgagg gtgacaatat tgttgtagga gataaagttg
      961 ttttgatgcc tgtgaatgca gggcagccac tacatgccag caacatagag cttcttgata
     1021 acccagggtg taaagaggtg aatgctgtca attgcaacac cagctggaaa atcactttat
     1081 tcatgaaata tagttcctat cgagaggatg tattaaaagg aggggacgtt gttagattat
     1141 ttcatgcgga acaagagaag tttttgactt gtgatgaata tgagaaaaaa cagcacattt
     1201 tccttcgtac gaccttgcgc caatcagcta cttctgctac tagttctaaa gcactctggg
     1261 aaatagaggt ggttcatcat gacccatgcc gtgggggtgc aggacagtgg aacagcttgt
     1321 tcagatttaa gcatcttgca actggaaact atttagctgc agagatggag gggtgcagtt
     1381 gttttttaat tgattgcggt acaagcatga ctttcactgc ccagcttaat cctgattatc
     1441 gagatgccca aaatgaagga aaaaatgtga gagatggagt ccctccaact tcaaagaaaa
     1501 aacgccaggc aggggagaag atcatgtata ctttggtttc agtcccgcat ggcaatgaca
     1561 ttgcatccct ttttgaacta gatgccacaa ctcttcagag agctgactgc ctggttccaa
     1621 ggaactcata tgttcggtta aggcatttat gcaccaacac atgggtaacc agtactagta
     1681 tccccataga cacagatgaa gagaggcctg ttatgttaaa gattggaacc tgccaaacca
     1741 aagaagataa agaagcgttc gcaatcgtgt ctgttccact gtctgaagtt cgagacttag
     1801 actttgccaa tgatgccaat aaagtactag cgaccacagt taaaaagcta gaaaacggca
     1861 caataactca gaatgaaagg aggtttgtaa ccaaattatt ggaagatctc atattctttg
     1921 ttgctgatgt gcctaataat ggacaagaag ttctggatgt ggttatcact aagccaaacc
     1981 gagagcgtca aaaattgatg agggaacaaa acatactggc acaggtattt ggaattctta
     2041 aagcaccctt taaagagaaa gcaggagaag gctcgatgct gagacttgaa gatctggggg
     2101 atcaaagata tgcaccctac aagtacatgc tgcggctctg ttaccgcgtc ctgagacact
     2161 cgcagcagga ttaccggaaa aatcaggaat atattgctaa gaatttctgt gtcatgcagt
     2221 cccagattgg ctatgatatt ttggcagaag atactatcac agctttgttg cacaacaaca
     2281 gaaaactact agagaaacat atcacagcaa aagaaataga aacatttgtc agtttactca
     2341 ggagaaatcg ggagccaagg tttttggatt atttgtcaga tctgtgtgtg tctaatacca
     2401 ctgctatccc tgtaactcaa gaactcatct gtaaatttat gttgagtcca ggcaatgcag
     2461 acattctcat tcaaactaag gtggtctcaa tgcaagcaga caaccccatg gagagctcca
     2521 tcctttcaga tgacattgat gatgaagaag tttggctcta ttggattgac agcaacaagg
     2581 aacctcatgg caaagctatc aggcaccttg ctcaagaggc aaaagaaggc accaaagctg
     2641 acttagaagt tcttacctat tacaggtacc agctaaacct ctttgcaagg atgtgcttgg
     2701 atcgccagta tctggccata aaccagattt ctacacagct gtctgtagac ctgatcctgc
     2761 ggtgtgtgtc ggatgagagc ctgccgttcg acctccgagc gtccttctgt cgcctcatgc
     2821 tccacatgca cgttgaccgg gatccccagg agtccgtggt gcctgttcgc tatgccaggc
     2881 tctggacaga aatccccaca aagatcacaa ttcatgaata tgattctata acagactctt
     2941 ccagaaatga tatgaagagg aaatttgccc tgacaatgga atttgttgaa gaatatttga
     3001 aagaagttgt aaaccagccc tttccttttg gggataaaga aaaaaataaa ctgacatttg
     3061 aggtggtcca cttggctcgg aatcttatat actttggatt ttatagtttc agtgagttat
     3121 taaggctaac aagaacactt ctggctattt tagacattgt acaggccccc atgtcatcat
     3181 actttgaaag attaagcaaa tttcaagatg gaggaaacaa tgtgatgaga accattcatg
     3241 gggtgggaga gatgatgacc cagatggtac tcagtagagg ctccatcttc cccatgagcg
     3301 tgccggatgt gccacccagc atccacccga gcaagcaagg gagccccacc gagcacgagg
     3361 atgtgactgt gatggacacc aagctgaaga tcattgagat tttgcagttt atcctgagtg
     3421 tcagactgga ttataggatc tcatatatgc tgtcaatata taagaaggag tttggagagg
     3481 acaatgacaa tgcggagaca tctgccagtg gatctccaga cactttacta ccatcagcta
     3541 ttgttcctga tatagatgaa attgcagctc aggcagaaac tatgtttgcg ggaagaaaag
     3601 aaaaaaatcc agttcaactt gacgatgaag gaggcaggac gtttttacgg gtcctcattc
     3661 atctgatcat gcacgactac ccgcctttgc tgtctggagc cctgcagctg ttgtttaagc
     3721 acttcagcca gagggcagag gttttacagg catttaagca ggtgcaatta ctggtgtcta
     3781 atcaagacgt agataactac aagcaaatca aggcagatct agaccagctt cgactgacag
     3841 tagaaaagtc tgagctatgg gtggagaaga gcagcaacta tgagaatgga gaaatagggg
     3901 aaagtcaagt gaaaggtggt gaagagccaa ttgaggaatc aaacatttta agtccagtgc
     3961 aggatggaac aaagaaacct cagattgaca gcaacaagag caataactac cggattgtaa
     4021 aggagatttt gatcaggcta agtaaactct gtgtgcagaa taaaaagtgt cggaatcaac
     4081 atcaacgatt actgaaaaat atgggggcgc attcggtggt gttggatctt ctgcagatac
     4141 cctatgaaaa gaatgatgaa aagatgaatg aagtaatgaa tctagcccat acatttctgc
     4201 agaatttctg tcgaggaaat ccacagaatc aagttcttct tcataaacat ctgaatttgt
     4261 ttttaactcc aggtctcctt gaagcagaaa ccatgcggca catcttcatg aacaattacc
     4321 atctgtgcaa cgaaattagc gagagagttg tacaacactt tgtgcactgc attgagacac
     4381 atggccgcca cgtggagtac ctgaggtttt tgcaaacaat tgtaaaagca gatggtaaat
     4441 atgtgaagaa atgccaggat atggtaatga cagagttgat aaatgggggt gaagacgtgc
     4501 tgatatttta caatgataga gcatcatttc caatccttct ccatatgatg tgttcagaga
     4561 gagaccgagg ggatgagagt ggccccttag cctaccacat caccctggtg gagttgctgg
     4621 cagcatgcac agaggggaaa aatgtctaca ctgaaatcaa gtgtaattcc cttctcccgc
     4681 tggacgacat agtgagggtg gtgacccatg acgactgcat ccctgaggtt aaaattgctt
     4741 atgtgaactt tgttaatcac tgttatgttg acactgaagt ggaaatgaaa gaaatctata
     4801 caagtaacca catttggaaa ttatttgaga acttcttggt ggatatggca agggtttgca
     4861 acacaactac agacaggaaa catgcagaca tctttttgga aaagtgtgtt actgagtcaa
     4921 taatgaatat tgtgagcggc ttctttaatt ctcccttttc agacaatagt accagcctcc
     4981 agacacatca gccagttttt attcagctac tgcaatctgc cttcagaatt tacaattgca
     5041 cctggccaaa cccagcgcag aaagcctcag tggaatcctg tatcagaact ttggctgaag
     5101 tggcaaaaaa tcgtggaatt gccattccag tggatttgga cagccaagtt aatactcttt
     5161 tcatgaagag ccattcaaat atggtgcaga gagcagcaat gggttggaga ctatcagctc
     5221 gctctgggcc acgctttaag gaagctcttg gagggcctgc ttgggattac agaaatatta
     5281 ttgaaaagtt acaggatgta gtggcctcct tggagcacca gttcagccca atgatgcagg
     5341 ctgaattctc agtgttggtt gatgtattgt acagtccaga actgctgttc cctgagggaa
     5401 gcgatgcaag aataagatgt ggcgctttca tgtcgaagtt gattaatcat acaaagaaac
     5461 taatggagaa agaagaaaaa ctgtgcatta aaattcttca gacattacga gaaatgttag
     5521 agaagaaaga cagctttgtg gaagagatta agtggtccaa agaaaatgac tgcatttctg
     5581 tgcatgctga ttgtctttgg cattctgcga cctgactgct taacagtgga agtgatttgg
     5641 ggacatggaa aaagctgaca ttgtgatctt ctcactcctc cttctctagc ctgctaaagc
     5701 tgtaagtaaa caggtgtgtg gtcaggtctt gtcaacaaag tctgtgggaa gcatcttctt
     5761 ttcttatgga agctacatgt cttcttctca tcctttatta tgtttaattc tgaaatggtt
     5821 ggcaaatacc actatggctt ttctgtcaca tctggaagat gtgtagtctt attttatgag
     5881 aaggagtaaa aggatggtgg gtggagtagc ctggttgtaa ttatagtgta cgtttatttg
     5941 gaaagactag catattagta tgcagtggct agattaatta aactcagctg gcataattca
     6001 atatggttag ttcctgtaaa agcaaactgt ctttaaactc ttgaggtttg ctataaagct
     6061 tatgatgaga gcaacatttt gaatgtctct tcctcccata tgaattacaa aggcacttaa
     6121 aagctgtcct tttaaaaatt tgtttccctt ctctccccac ccccaccccc caccacacac
     6181 acacacacac acacacacac acacacacac acacacacaa aacccttatc tacttgttaa
     6241 caaaataaat tctgggatct ttttttagga agatgagggc ttttttaact aacatatttt
     6301 gtgaaccata atttccatga agttgtttat aattttgagt ttctacacat caagtagtgt
     6361 gaggtatcca tggaaactgt ctagcctata ttcagtgcac tggaccgcct tcccacacag
     6421 gtcaagactc aaacagttcc agatactagc ttgatttatt gtgccctaaa cattagacag
     6481 ttttaaaagg aaattggctc ctaattgaca catacaattt catgtttaat tagcaatttg
     6541 agcctgtcta cattttacta acagatgtaa cattcaaaac gtgccattct aatatatctg
     6601 ttgcacagat gcacctaaat gcagaacttt atgaaatagc agctcagctg cttagcaaaa
     6661 atttggacag aactgacatt attttcctta agagatgtac tttaatgtta tttaaggagt
     6721 gattttcctt aaccaatcta atggatttat tttatatttt ggtaacagct ttattgagat
     6781 attcacatac tataaaattc accctacaaa agtgtacaat ttagtgtttt ttggtttatt
     6841 tacagattta caaccaatac tgctgtttaa ttttagaaca ttttcatcac ccctaaaaga
     6901 aaccccatgc ctcttagcag tcactcttca ttcttcccag ccccagccct tggctatcta
     6961 ttttctgtct ctttttgtct ctatgaattt gcctcttctg gacatttcat ataaatggaa
     7021 tcatacaata tgtggtcttt tgtgactgcc tcccttcact tggcataatg ttttcaaggc
     7081 tcatacatgt tctagcaggt gtcagcactt cagtcccatt ttattgccaa ataatattct
     7141 attatgtgca tataccacat tgtgtttatc cagtcatcat ttggtggaca tttggattgt
     7201 ctctactatt atggatcatg ccacaatgaa cattctgtac aagttcttgt gtggacctct
     7261 gttttaattt ctttagggta aatacttagg agtggaattg ccggaatgta tggtaactct
     7321 acgtttaatt ttttggaact gccaagtggc tgcaccattt tctattccca ttagcagtgt
     7381 atgagggtcc caatttctcc acatcctcac caacatgtgt tattgttcag atcacaatgt
     7441 cagctttttc cgtgtcccca gatcacttat tttagccatt ctagtgggtg tgagatggta
     7501 tcaaggggca acttttttta aaaggagaga aatttaatat tgtccatggt tcataaatta
     7561 gttcaatgtg tgtctcttac ttgtttgctt ttccattact cttgatttgt aagataaata
     7621 tacctctcat ctctatcaat attgtcactt tccttactaa ttttaatgta ggggcctatg
     7681 atatcaaaat ttacagtagt gaattgggct acatatagaa aatgtatcat gaaaaaggga
     7741 aaacactgaa ataactgttc gattgcaaag gttaaatctc taaatttctg tatgttttca
     7801 tcttacttga ctttaactag aaaacaggta taatagtgat gccacatact gggaagcaat
     7861 gagtatttga tacaatgcca gattaaaagg tgtacttatt ttttcgttca atatagttca
     7921 tcaatcataa aataccatca atcataaata aggcatacca taattttatg tatccctaaa
     7981 aataaataaa tgctgccaat taaactaaag cacaccatgg attttaaagt gacctgtaat
     8041 ttagaaatgt taaaacatgc aggagagaaa tgggtgtgtt agaatcaatg aaataaagca
     8101 gaaaagagat gtgcttgctc agtgtttttt gaaggcaacc cagtcattta tgcttaccaa
     8161 cacccagggg agatagcaag aatcttcata cttcaaagac ctaattcatt ttacaaatat
     8221 gcatcaatat ccatgagtac aaaaatagat atacgtatat attacacaca tacacactga
     8281 catacacaca cacacacaca cacacacaca cacagagaca gagagagaag agtagagaga
     8341 tattcattga ctcattcttc cacaccttag gagtattaga tcagcatcag caacctgtag
     8401 ttcactgaaa tgattcttcc tctcttcaat tcactgattc agaaaagctg gtttacctca
     8461 aataatgttt attaaatact ttaagctttc ttttcagcct gagaatgttt catcttgttt
     8521 tttccagaag ctaatttcaa taggtgaatc acaaacctgt gaaaatccac atttataatt
     8581 cagaggctag caccacagta ctaccaagcg gctatgcttc cttaccagca aatgtgcttt
     8641 gcatgttatt aaaaataaac gtttactttc ttagtgcccc ggattatagt tacagttcta
     8701 aatgcattaa agtagtgaaa tatctatcac ggtgtatgcc acagggaatc aaactgattt
     8761 ccaaaataac attcataaga ccataataag tctaataaag cctttcttaa aaagaccctt
     8821 tctaaggtaa gcatttggta cttggcccct ttaattagct caggcatctc taggtttgtt
     8881 tgaactgaga cctcattttc ttttagtaat aattgtgtta ctgctttgaa atgttgatga
     8941 aaatttaaag gatttctatt tttcattagt tctaaatcat tgtctcatag ttttctctct
     9001 gcaaaattct ttgaaaattg tggtttacat gtagaacaca attaggagct catgggagca
     9061 gataattgct catattaaag taggccaaat atgtggcctc ctggacaaat agatgcaaga
     9121 aatgattaag attagattta tataattttt aatgtagcaa tgaacactaa agaaatgaaa
     9181 tgatttattt catgaggaaa aatgaggtaa aagaattatc tttatcttct attataaatt
     9241 atgacacatt caaacatatt ttaaaagaga atagtgaatt tgtatctctt caaattgaca
     9301 tattcacata atattaggaa ttatgttgct gagtcagatc cttgtatgac gtgcagcctt
     9361 aaggtggttt ctttgttttt tagtaaaata cgaaaatcct attgcagtag acatattgta
     9421 gcagggggat aacctggact ggacttttgg gatattagtg tgttctcttg cattaggcta
     9481 catttgtgat cattaattag tattttacct tctaatcttt caggctaaat attgaaattg
     9541 tctgtctttt aagttttata acattttgct tgctggattt caacacaatt tccttctttc
     9601 agccgaccat aggtaatgag ttttgtgtgc taattttttt tttttttttt tttttttgag
     9661 acaggattcc tactcccagg ctggacaggg tctcccaggc tggagtgcag tgtgcaatca
     9721 tgcctcactg cagccttgat ttcccaggct caagcgatcc tcccacctca gcctcctagt
     9781 agttgggacc acaggcgtat gtcaccacac ccagattatt ttcctatttt tattagagat
     9841 gaagtcttgc taagtttccc aggccagtcg taaactcctg agctcaagtg atcctcctgc
     9901 ctgggcctcc tgagtaactg ggaccatagg tgtatgttat cacaccaggc taattttttt
     9961 ttttttaatt tggtagagaa gaggtctccc tatattgcct aggctggtct tgaactcctg
    10021 ggctcaagaa atccttctgc cttggcctcc taaagtgctg ggattacagg catgagccag
    10081 taatacaatg taatatttac atattaagta tttttagtac aaggctgggc atcttgtatt
    10141 tttagtacta tgctaaatat ttgaatattt ttagtacaag gctgagtgcc ttgtagtttt
    10201 agtattaata caaggcaccc agccttgtac taaaaatatg taatatgcaa gtaacattga
    10261 ataaatctca aatgttttcc aaagttatca gacatgatat acaacaaata tcagccatcc
    10321 ttgaataggt tggcactcag catcaaattt tgttgataaa ttgagtgatc tctcattcaa
    10381 aatcattgat tcatacattc agtcaaaaat atttattgag tacttagttt gctagctttg
    10441 gggctaggtg ttggaatcaa tggtcagcca aaaaggaaaa aaagaaaggt atagttcctg
    10501 tcctcatggt acttataatc taatagaggg tgatagaaat cattgaaaga ttggtataaa
    10561 taaatataca gctaaagcac atggtgatat acatgctatt ataagaggac ttaatgagaa
    10621 ttgacttggt gcggttagag aggatgactc tgaggaagat atggttgagc tgagatctaa
    10681 aggttaagta ggaattaagt aaagccagga ggactcaggg tcgggggaca gaaagcatgg
    10741 ctggtgaaag agaacatcat ctgttaatgt cttgaagcag aagggagcat gataagacac
    10801 taagaagctg tgtggcagaa ggaagatgtg gattgttcag aagacaatga gacagtggct
    10861 caaatctgta ggtgttgcat tgtgtatcat cccctaaagt aatgctatgg attttagcca
    10921 ggattcaaag agagctggaa agtaacagaa catcctatgt aggaagctgt catcatgatg
    10981 tctaatagtt cttgagcatt ttcttttcct ataatattga atttttatga agaaatatat
    11041 acaacataaa ttttagctat aaagcattaa atataataaa gactcatgac ctcagccaaa
    11101 tgaagaatga gaacattacc tgtaacttgt gtctacatat gtgttctggc ctccccttcc
    11161 agaggtagct cacgttttga ataccatact gcatatcttc taggacttcc ctttttttcc
    11221 ctgtcatcat tctatttcta acattcatga aagtagttgt gtgttacggt gaggctctgt
    11281 ttaatccatg tttactactc tataatattc cagtttggga atattctata atttatttgt
    11341 caattttcct gtcacttgtt atttgggttg attccaggtg atgttttgct tgttgtttgt
    11401 tttgctattg ctatcatgca gatataaatg tctaggatgg gatactattt gtttccttga
    11461 gcatgtttcc cctgggagtg aaattggtgg ctgagagcat acattgatgt gatttccaaa
    11521 gtagttgtac caatttgcat cccacattct cttgatccat gtcctcttca acacttgatt
    11581 ttgtaagact tcttaatttt tgtcaattta ttgggtataa aatggtgtct ccaccatttt
    11641 attagcattt ctttgattac caatgaaggt gagcattttt tttcatgttt attggctgta
    11701 tgtgtttctt atatgaaatg ccagttcagt tcttctgtca gcttttctac aagattctta
    11761 atgatttata aacactcttt gtatagtcat gtattctgaa taccagtcat ctgttgtttt
    11821 gcaagcctct gaatgttaag tgagcaatga cttagagggg catcctgtgg atatggagag
    11881 acatatggat atgtgttagg aagcacagcc tttccactaa tgaacaattg ttgctgataa
    11941 taactttata aatatactta atacatttct tgtgttaaaa ctaaatagga gggaaaatag
    12001 ctcttttccc acagaacatg gaatattggt tttccattta acactacttc aaggaaaggc
    12061 tgtctaaatt atcttctgaa gaattctgct ttgtacatgt aataggggtg attgaaacct
    12121 atccacaagt aagtgttatt tttaagaaat tgtagcatac tgatcaaatt ggcttcaaag
    12181 tagtctttca caaaatgaat gctgtttttc atttgccttc tcttgaaaaa ttatagaagg
    12241 ttggagctgg atattgatgt cagctgtgaa aaccatggct gtcttgtggc actgggcatt
    12301 gtaatgtcct ctttatgtca tcaattgtac aagtcttccc cagattgaaa cttattaatg
    12361 ctttccttta aacataaaat aaaatattac agtagctgtt tattcagtac ttgctatggg
    12421 ccaagaacat aaagcttctc ctatttaatt tcctaatcct taaatagcct tgcagtgtaa
    12481 atattattat ccacagatgg ggaaactgag ccttggggca gttaattaaa attctttaga
    12541 tcacaaagcc aataagtgga agaacccaga ctcaaaccaa tcacattact ctctgagaca
    12601 tcatttccac taaggtccac taacgtgcat tgtcattgcc aatgccggga gcattcataa
    12661 actgaacttc ttatgtatta aagtgtgtat agatattatc tcatttaatt ctcaaggttt
    12721 ccctttggag ttgtgccatg tagaactcct ctattccatg gattccatag actgtcctat
    12781 ctgaggaact tctaaatgta ttctgaattt attaaaattt agcttcatac atattttgtc
    12841 aaatattgca ttgattgata agtaatacca gtgccagttt tcttcctctc ttttaagaat
    12901 aatctatttc tagtattttg gggaaaaata atgaggtctt tgtctctcac ttaatccgtg
    12961 tgtgtgtgtg tgtgtgtgtg tgtgtgttgg tggggggcag tgggtcttct accccattgt
    13021 ttccttgcca gctcttcgga gccatgcact cgtctcactg ccctgtgaac cagccacact
    13081 ctcttgtttg tgggtcagga ggtcacagct tgaagatcaa ggactgcact actgttgaga
    13141 atgcaagaaa ctccatagaa acaggaaggc caatatagag caggatagtg ctggtgatat
    13201 gtccccgtat gtattgttcc tcatctcctg tgacaccacc ttccaaagtt gtgcctgtct
    13261 tcactaaatg attatggaaa tataacagac atcacagaat ctggggatag aactttaaaa
    13321 cagcaaacta gttatgactt tccccattgt ctaggaggaa gacctttctc ccactgaagt
    13381 tcatattgct attcagatca gtgtcagtct tctcatttat ttaaatctca ttccatctcc
    13441 tgctctttcc tcttgtactc tctgggatgc actgtaagct gagtccatta ctgagttaca
    13501 tactttgcct taccccccac tcagcaacat agtctttgca gaagctttga aattacctct
    13561 tgaagttcca ttttccccag tctttggtga gcatgcacac gcctgcactg acagcactga
    13621 tttcattctt ttcagtaaca aacagtactc tagtaggttt ttatactgtg taccagggac
    13681 tatgggcttc actttaatga ttgtgtgcca ctgtctttga gtgtgatttt atgaggcact
    13741 gatttatgtt atgtgaatac agtcattttc cttcattaag gagatggtat ctaaagcttg
    13801 tctgctcact tcttgcttac ttaccctcct ctcagcttaa agtcagaaga ctgcttattc
    13861 tgaaaactaa acaattacaa gcagtaaaat ccattcttaa gtcctattgg tgagggattg
    13921 cataagttct caaactctga atttcagcaa accctgtatt taaaatggtt gaggtagaag
    13981 ggtctgttgg gtttcatgtt agttagtatg cttcctggaa ttcaaatact gggaggtttt
    14041 aattaatgcc ccaaggaaaa caaatacagt ttgctttatt ccttgctatc tatggagtat
    14101 agaatcatct cctaacaaaa ccttctcagc aaccctgttt gtcttgaggc taggatattt
    14161 gataaactca gagtggttat tgaagtcact ctttcattca gcagcagcat caaatattta
    14221 aacctcatca tttactgttt aaacatttaa ttttcaccaa tggaatcaaa tggtctggtg
    14281 aggattattt atattggaaa acagtgccat atgtttcaac tccacatatc tgaaaattct
    14341 ttcagcatat gctgcagaat tgctttttgc atccactttt ctacttcctg acacatggta
    14401 gaaatgtaat aaatgtcttt acaatcaata aaaacaagga aagaagaaat ttggaagtag
    14461 gttgccatta tggtgaatga atatttggat ctaacatttt ccacagtctt gttttttcac
    14521 aaggctcttt actagaatca ttgagacatc atatattttt caagattgta atgagtatgt
    14581 cattgtgttg atgagaagag catcttctga gtgcacataa ctagtcctgt tgaaatttgt
    14641 gtttcctgtc ttaagaaagc taggcaaagg caacagggag agaaattgac ttacaacttc
    14701 ttggacaggg agactaagat gttcaaatga ttaaacagct agattatagg agattgacca
    14761 tattctcccg aaggagttat ctgaaaatat agttgattat aacgatggac agaatatcac
    14821 tccacaaaga tacagttgtt acattaatgt attgaaatga gaaatgtacc tttttacccc
    14881 tggcaattca aatgaggaaa aatacctaat cagacgtatt gttactaagc caaaaggtta
    14941 cagaaacaca aattatgcta ataccaagtt taatgttaaa atgggactat ggggagacta
    15001 acaggtacct atcatcacct ccttgtagat cttgtctcag ctgattggta gcttatcatg
    15061 aatctttgag gataagtctt aaattgggca tccttagttt gcagttttta ttacattttg
    15121 aatttctagt tgaggactta gttttctagg atgctggttg tgttttttca tgatatcttg
    15181 attatatttt acataatgaa aaaatattac tttagtaaat tgtttttcta aggggatggg
    15241 aatgaatgtg ggtagctata cctcaaatat cacacatcct tgaagtcttc attcctaagg
    15301 ctattaactc cccattaagg caaacagagt tgtgctttct caaaaatgaa acaaaatttt
    15361 agtcctttct aggatgcata aatttgatta tcctttctat ccatgaaagg caatgatttc
    15421 tgaacttttt aatttttgat gcattggact cggtgtaaca gggagtgggt gggaaaaacc
    15481 caatcctccc agatattcac aaaccatcag caggacttct ctggccacaa aagatgtctt
    15541 tttatggaga tattttgttg taatttcaga aggtggttgt tagttttctt ggctacatta
    15601 catttagcac atctgggatg tgttcacatg aagacattgg ctaaaagtag tgtcttgtgg
    15661 cctggaattg actctgatat tgaaaaggct gtaaaggaca ttccttgctt gtcctcactc
    15721 agcaaagaga ccttccatgg gaggtgcatc aggaatgcat tttggatttg aagaaccagc
    15781 acagaagtca aacttctcaa ctgtggtgaa attcttttca taatggccta atgtgctttt
    15841 agttcttccc tcatttctgc catggcaatt atagctctga gacaattatt tgcaaccctg
    15901 gcaccagaat ttctgacaat gattctgcag ttacttttga attaaagtaa tttggggaaa
    15961 tgactcacat ttaagctacc accactgcac agatagtgca aactatcaag aatgccccaa
    16021 aagcaaattg ggacacagta catgtctctc accgcttaag tcagaactgg atagttgaca
    16081 agagaagtca gtttctgctg aacttgtgat gtagcaatat ctgaattttt ttattcttaa
    16141 atgaagatta ctaagacata acagaatctt gttctgttta tacctattca ttaatcattt
    16201 ttagcaccag agtttgtctt agcacaaaac tctgaagttt gaaccaagac agaatttgtt
    16261 ccaactttag ttgaagttgt aagggtacat tttatatagt gaagtatatt catgctttag
    16321 ggtgactttg ccatgttagc taataagtat ataattctaa ggactgatta atagttaaaa
    16381 agctaggatt taggggcagt ttatcattta ttatttttca cattttctta atatactgga
    16441 aatttatttc acttttgtgg gaaggtttgg tataacataa gaaagtgtct gcaaaagcac
    16501 tttgcaagtt gtagactgtt cccatgatct ggataatatt aatactagca gggataacat
    16561 caacaatgta caacttttat agcacttact atgtgtttgg aactgttcca agtactttca
    16621 gtaaatttta actatttaat tatcacagaa atcctctgag agtagatatt aacaatttca
    16681 tttgacaatt gagggactga ggcccagagt gatgaagtaa cttgtttaag atccccagtt
    16741 agtatatggc atagagggga tttaaaccca ggcagagtgg cttcagagtt gacaacagaa
    16801 aaataggaag cccctgcctt ttctatggca gtctgaatat tacatggtga ggaaatagat
    16861 gcttctaatg gggctataat tgaataagaa gagtgttact cgtttgattt tgatgtctat
    16921 gaatctgata ggcactgtga ttatatctgc cgaagagaat ttaaaaataa tcacaaatat
    16981 gatgcttatt tttatttggt gtgacataat tctactcttt ggttggtttt caatagtttc
    17041 attattctag cagtataaac ggcattttaa aaagtaaatg gtaaaaaagt tttctatttc
    17101 atctttaaaa aaatttattt gtttatctgt tggttgggtt cttgtagcag tgtgataaat
    17161 ggtgtgatta aaagattctt ccagggccag gttcatgtct gtaatcccag aactttggga
    17221 ggccaaggtg agagggttgc ttgaggccag gagtgtgagg ttgcaatgag ctatgattgt
    17281 gccactgtac tccagcctgg gcaacacaac aagaccctat ctctaaataa taatagaaat
    17341 aataatacat aaaaggttct tgcagagact aaaaggggag ctagttctca agggttcagt
    17401 cctcttcaca ataggttccc tttcagacag tgatgctgac ttgtgcaatt tcaagaaaaa
    17461 gtcctggatt ttcacactgt cagctttagt tattacaggt gggccaactg tcttctacag
    17521 ggttagagtg agtggtctgt agaggtgaga tccatgaata gtacaacaaa ctgagctact
    17581 ctttaaaaaa atgagtgctt cagttaatgt gacctcatat ttttctcccc aacttataac
    17641 ttcaaccctg tagtttatgg gtctaaaaga tttttcatag catctccttc tactataatg
    17701 agagtcgcag taattaccca aaggcgttga ctccaaagaa aagctttgtt ttgtttttcc
    17761 tttccttttg gaagaaattt tctttggcca ggtgaattta attcaactca aaggactttc
    17821 tcttaaaaaa agaaacagta aggacgattt tcatgtctta tgtttcttct aggtgctgca
    17881 cttaagtgtt atcaggaata gtaaatagta gagttgtatt ccttggtaga ataagctgtt
    17941 atacttcact gtttcttttg agactagtca ccacctttac ttactacacc ccattatgaa
    18001 gaggtcttaa agaaagaaaa catgaaatag gaagcaataa taactgtcta tgttctaaga
    18061 atttaagtac caataaataa aagttgttac aaggataaac aaactccaga cactctgagt
    18121 gtctattaga attcttggca ctgaccgggc acggtggctc atgcctgtaa tcccagcact
    18181 ttgggaggct gaggccggca gattgcctga ggtcaggagt tcgagaccag ctctggccaa
    18241 catggtgaaa tccagtctgt actaaaaata caaaaaacaa aacaaaacaa acaaaaaaaa
    18301 ttagccaggc gtggtggtgt gtgcctgtaa tcccagctac tcgggaggct gaggcagggg
    18361 aattgcttga accagggagg tggaggttgc agtgagctga gattgtacca ctgcactcca
    18421 gcctgggcaa cagagtgaga ctccgtttca aaaaaaaaaa aaaa
//
