LOCUS       XM_011543380            2390 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ISL LIM homeobox 1 (ISL1), transcript
            variant X1, mRNA.
ACCESSION   XM_011543380
VERSION     XM_011543380.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000005.10) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011543380.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2390
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
     gene            1..2390
                     /gene="ISL1"
                     /gene_synonym="Isl-1; ISLET1"
                     /note="ISL LIM homeobox 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1 EST,
                     295 long SRA reads, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 7 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:3670"
                     /db_xref="HGNC:HGNC:6132"
                     /db_xref="MIM:600366"
     CDS             413..1270
                     /gene="ISL1"
                     /gene_synonym="Isl-1; ISLET1"
                     /codon_start=1
                     /product="insulin gene enhancer protein ISL-1 isoform X1"
                     /protein_id="XP_011541682.1"
                     /db_xref="GeneID:3670"
                     /db_xref="HGNC:HGNC:6132"
                     /db_xref="MIM:600366"
                     /translation="MEPIKIVPWLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCV
                     ACSRQLIPGDEFALREDGLFCRADHDVVERASLGAGDPLSPLHPARPLQMAAEPISAR
                     QPALRPHVHKQPEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRV
                     IRVWFQNKRCKDKKRSIMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQANPV
                     EVQSYQPPWKVLSDFALQSDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPN
                     SMVASPIEA"
ORIGIN      
        1 attgtttact agattggtgt gtaaacgcaa gattctagag aaggagagcc cacttcagga
       61 gtatctttac tgctatggaa atagtatttt gctcaattgc acacaggctt gcatgtgcct
      121 aattctggat acacacatgt gtagaaggaa ctaatcattt ttaccttctc ttcactctct
      181 ctcaactctg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtaatct tgtagttgta
      241 aaagcagaac agactggaca gttagatttc cacatctctc cttggagaag caggatgcct
      301 cctcctgtta tgtggatctt ttcctctctc ttccattctt tctgttcgta ggaatgcccc
      361 agcttctgtt attcctgaaa gatggagaag gggccaggga agtgcagcct agatggaacc
      421 tataaagatt gtcccttggt tgtacgggat caaatgcgcc aagtgcagca tcggcttcag
      481 caagaacgac ttcgtgatgc gtgcccgctc caaggtgtat cacatcgagt gtttccgctg
      541 tgtggcctgc agccgccagc tcatccctgg ggacgaattt gcgcttcggg aggacggtct
      601 cttctgccga gcagaccacg atgtggtgga gagggccagt ctaggcgctg gcgacccgct
      661 cagtcccctg catccagcgc ggccactgca aatggcagcg gagcccatct ccgccaggca
      721 gccagccctg cggccccacg tccacaagca gccggagaag accacccgcg tgcggactgt
      781 gctgaacgag aagcagctgc acaccttgcg gacctgctac gccgcaaacc cgcggccaga
      841 tgcgctcatg aaggagcaac tggtagagat gacgggcctc agtccccgtg tgatccgggt
      901 ctggtttcaa aacaagcggt gcaaggacaa gaagcgaagc atcatgatga agcaactcca
      961 gcagcagcag cccaatgaca aaactaatat ccaggggatg acaggaactc ccatggtggc
     1021 tgccagtcca gagagacacg acggtggctt acaggctaac ccagtggaag tacaaagtta
     1081 ccagccacct tggaaagtac tgagcgactt cgccttgcag agtgacatag atcagcctgc
     1141 ttttcagcaa ctggtcaatt tttcagaagg aggaccgggc tctaattcca ctggcagtga
     1201 agtagcatca atgtcctctc aacttccaga tacacctaac agcatggtag ccagtcctat
     1261 tgaggcatga ggaacattca ttctgtattt tttttccctg ttggagaaag tgggaaatta
     1321 taatgtcgaa ctctgaaaca aaagtattta acgacccagt caatgaaaac tgaatcaaga
     1381 aatgaatgct ccatgaaatg cacgaagtct gttttaatga caaggtgata tggtagcaac
     1441 actgtgaaga caatcatggg attttactag aattaaacaa caaacaaaac gcaaaaccca
     1501 gtatatgcta ttcaatgatc ttagaagtac tgaaaaaaaa agacgttttt aaaacgtaga
     1561 ggatttatat tcaaggatct caaagaaagc attttcattt cactgcacat ctagagaaaa
     1621 acaaaaatag aaaattttct agtccatcct aatctgaatg gtgctgtttc tatattggtc
     1681 attgccttgc caaacaggag ctccagcaaa agcgcaggaa gagagactgg cctccttggc
     1741 tgaaagagtc ctttcaggaa ggtggagctg cattggtttg atatgtttaa agttgacttt
     1801 aacaaggggt taattgaaat cctgggtctc ttggcctgtc ctgtagctgg tttatttttt
     1861 actttgcccc ctccccactt tttttgagat ccatccttta tcaagaagtc tgaagcgact
     1921 ataaaggttt ttgaattcag atttaaaaac caacttataa agcattgcaa caaggttacc
     1981 tctattttgc cacaagcgtc tcgggattgt gtttgacttg tgtctgtcca agaacttttc
     2041 ccccaaagat gtgtatagtt attggttaaa atgactgttt tctctctcta tggaaataaa
     2101 aaggaaaaaa aaaaaggaaa ctttttttgt ttgctcttgc attgcaaaaa ttataaagta
     2161 atttattatt tattgtcgga agacttgcca cttttcatgt catttgacat tttttgtttg
     2221 ctgaagtgaa aaaaaaagat aaaggttgta cggtggtctt tgaattatat gtctaattct
     2281 atgtgttttg tctttttctt aaatattatg tgaaatcaaa gcgccatatg tagaattata
     2341 tcttcaggac tatttcacta ataaacattt ggcatagata aataaataaa
//
