LOCUS       XM_017008960            5637 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens IQ motif containing GTPase activating
            protein 2 (IQGAP2), transcript variant X6, mRNA.
ACCESSION   XM_017008960
VERSION     XM_017008960.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000005.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017008960.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5637
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
     gene            1..5637
                     /gene="IQGAP2"
                     /note="IQ motif containing GTPase activating protein 2;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 1 mRNA, 56 ESTs, 828 long SRA reads, 4
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 22 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:10788"
                     /db_xref="HGNC:HGNC:6111"
                     /db_xref="MIM:605401"
     CDS             262..4818
                     /gene="IQGAP2"
                     /codon_start=1
                     /product="ras GTPase-activating-like protein IQGAP2
                     isoform X5"
                     /protein_id="XP_016864449.1"
                     /db_xref="GeneID:10788"
                     /db_xref="HGNC:HGNC:6111"
                     /db_xref="MIM:605401"
                     /translation="MPHEELPSLQRPRYGSIVDDERLSAEEMDERRRQNIAYEYLCHL
                     EEAKRWMEVCLVEELPPTTELEEGLRNGVYLAKLAKFFAPKMVSEKKIYDVEQTRYKK
                     SGLHFRHTDNTVQWLRAMESIGLPKIFYPETTDVYDRKNIPRMIYCIHALSLYLFKLG
                     IAPQIQDLLGKVDFTEEEISNMRKELEKYGIQMPSFSKIGGILANELSVDEAALHAAV
                     IAINEAVEKGIAEQTVVTLRNPNAVLTLVDDNLAPEYQKELWDAKKKKEENARLKNSC
                     ISEEERDAYEELLTQAEIQGNINKVNRQAAVDHINAVIPEGDPENTLLALKKPEAQLP
                     AVYPFAAAMYQNELFNLQKQNTMNYLAHEELLIAVEMLSAVALLNQALESNDLVSVQN
                     QLRSPAIGLNNLDKAYVERYANTLLSVKLEVLSQGQDNLSWNEIQNCIDMVNAQIQEE
                     NDRVVAVGYINEAIDEGNPLRTLETLLLPTANISDVDPAHAQHYQDVLYHAKSQKLGD
                     SESVSKVLWLDEIQQAVDDANVDKDRAKQWVTLVVDVNQCLEGKKSSDILSVLKSSTS
                     NANDIIPECADKYYDALVKAKELKSERVSSDGSWLKLNLHKKYDYYYNTDSKESSWVT
                     PESCLYKESWLTGKEIEAFWKGYKQRKEYMHRRQTFIDNTDSIVKIQSWFRMATARKS
                     YLSRLQYFRDHNNEIVKIQSLLRANKARDDYKTLVGSENPPLTVIRKFVYLLDQSDLD
                     FQEELEVARLREEVVTKIRANQQLEKDLNLMDIKIGLLVKNRITLEDVISHSKKLNKK
                     KGGEMEILNNTDNQGIKSLSKERRKTLETYQQLFYLLQTNPLYLAKLIFQMPQNKSTK
                     FMDTVIFTLYNYASNQREEYLLLKLFKTALEEEIKSKVDQVQDIVTGNPTVIKMVVSF
                     NRGARGQNTLRQLLAPVVKEIIDDKSLIINTNPVEVYKAWVNQLETQTGEASKLPYDV
                     TTEQALTYPEVKNKLEASIENLRRVTDKVLNSIISSLDLLPYGLRYIAKVLKNSIHEK
                     FPDATEDELLKIVGNLLYYRYMNPAIVAPDGFDIIDMTAGGQINSDQRRNLGSVAKVL
                     QHAASNKLFEGENEHLSSMNNYLSETYQEFRKYFKEACNVPEPEEKFNMDKYTDLVTV
                     SKPVIYISIEEIISTHSLLLEHQDAIAPEKNDLLSELLGSLGEVPTVESFLGEGAVDP
                     NDPNKANTLSQLSKTEISLVLTSKYDIEDGEAIDSRSLMIKTKKLIIDVIRNQPGNTL
                     TEILETPATAQQEVDHATDMVSRAMIDSRTPEEMKHSQSMIEDAQLPLEQKKRKIQRN
                     LRTLEQTGHVSSENKYQDILNEIAKDIRNQRIYRKLRKAELAKLQQTLNALNKKAAFY
                     EEQINYYDTYIKTCLDNLKRKNTRRSIKLDGKGEPKGAKRAKPVKYTAAKLHEKGVLL
                     DIDDLQTNQFKNVTFDIIATEDVGIFDVRSKFLGVEMEKVQLNIQDLLQMQYEGVAVM
                     KMFDKVKVNVNLLIYLLNKKFYGK"
ORIGIN      
        1 aaacctgctg cgggaggcgg cggcgaccgg ccagggagcg agggaggaga gttcactttt
       61 acttcagtgt cagcgcgcgg cggccgtggc tggctctggc gagagagcac cgagggagtg
      121 ggtcgcagat cttcgggcgg ctaggggaaa tcggcgagag gcgggatccg agcgcgccgg
      181 cggggcgcag agcccgcgag cctggccagc gagggtagcc gcggggggcg cgccccgggc
      241 gggcccccgg agacgcgcag gatgccacac gaagagctgc cgtcgctgca gagaccccgc
      301 tatggctcta ttgtggacga tgaaaggctc tctgcagagg agatggatga gaggaggcgg
      361 cagaacattg cttatgaata tctgtgccac ttagaggaag ccaaaaggtg gatggaagtt
      421 tgcttagttg aagaattgcc accaaccact gaattggaag aagggctccg gaatggagtt
      481 taccttgcaa agttagccaa gttctttgcc ccgaaaatgg tatcagagaa aaagatctat
      541 gatgtggaac aaacacgtta taagaagtct ggccttcatt ttcgacacac agataatacc
      601 gtccagtggt taagagcgat ggagtctatt ggtctaccca agatatttta tccagaaaca
      661 acagatgtct atgatcggaa aaacatacca agaatgatat attgcattca cgcactgagt
      721 ttgtatctgt tcaaactagg aatagcaccc cagatccagg atttgttggg caaagtagac
      781 ttcacagagg aggaaatcag taatatgaga aaagaacttg agaaatatgg aatacagatg
      841 ccatctttca gcaaaatagg tggtattctg gccaatgaac tgtccgtgga tgaagctgca
      901 ttacatgctg cagttatagc cattaatgaa gcagttgaaa aaggaatagc agagcaaacc
      961 gttgtaacac taagaaaccc aaatgcggtt ttaactttag tggatgacaa ccttgcacca
     1021 gaatatcaga aagaactctg ggatgccaaa aagaaaaaag aggaaaatgc aagactgaag
     1081 aatagctgta tttcagaaga agaaagagat gcttatgaag aactgctgac acaagcagaa
     1141 atccaaggca atattaataa agtcaacagg caggctgcag tggaccatat caatgctgtc
     1201 attccggaag gtgaccccga gaatacgctg cttgcactga agaaaccaga ggcccagctg
     1261 cctgctgttt atccctttgc tgctgccatg tatcagaacg aacttttcaa cctccagaaa
     1321 cagaacacca tgaactactt ggcccacgag gagcttttga ttgctgtgga aatgttgtct
     1381 gctgttgctt tactaaacca ggccttggaa agcaacgatc ttgtgtctgt gcagaatcaa
     1441 ctcagaagcc ccgcaatagg cttaaacaat ctggacaagg catatgtgga acgttatgca
     1501 aacacactac tctctgttaa actagaagtt ttatcccaag ggcaagataa cttaagctgg
     1561 aatgaaattc agaattgtat tgatatggtt aatgctcaaa ttcaagaaga aaatgaccga
     1621 gttgtagctg tagggtacat caatgaagct attgatgaag ggaatccttt gaggacttta
     1681 gaaactttgc tcctacctac tgcgaatatt agtgatgtgg acccagccca tgcccagcac
     1741 taccaggatg ttttatacca tgctaaatca cagaaactcg gagactctga gagtgtttcc
     1801 aaagtgcttt ggctggatga gatacagcaa gccgtcgatg atgccaacgt ggacaaggac
     1861 agagcaaaac aatgggttac tctggtggtt gatgttaatc agtgtttgga aggaaaaaaa
     1921 tcaagtgata ttttgtctgt attgaagtct tccacttcta atgcaaatga cataatcccg
     1981 gagtgtgctg acaaatacta tgatgccctt gtgaaggcaa aagagctcaa atctgaaaga
     2041 gtgtctagtg acggttcatg gctcaaactc aacctgcaca aaaaatatga ctactattac
     2101 aacactgatt caaaagagag ttcctgggtc acacctgaat catgcttgta taaagaatca
     2161 tggctcacag gaaaagaaat cgaggctttt tggaaaggat ataaacaacg gaaggagtat
     2221 atgcacaggc ggcaaacgtt cattgataat actgattcta ttgtgaagat tcagtcctgg
     2281 ttccgaatgg caactgcaag aaagagctat ctttcaagac tacagtattt cagagatcat
     2341 aataatgaaa ttgtgaaaat acagtcactg ttgagagcga acaaagctag agatgactac
     2401 aaaacattgg ttggctctga aaacccacca ttaacagtaa ttcgcaaatt tgtatacctg
     2461 ctggaccaaa gtgatttgga tttccaggag gaactagagg ttgcacgatt aagggaagaa
     2521 gtagtgacca agatcagggc caatcaacag ctggaaaaag acctgaacct gatggacatc
     2581 aagattggac tgctggtgaa gaacaggatc acactagagg atgtaatttc acatagtaaa
     2641 aagctgaaca agaaaaaagg aggagaaatg gaaatactga ataacaccga caaccaagga
     2701 ataaaaagtt tgagtaagga gaggagaaaa acactagaaa catatcagca gctgttttac
     2761 cttttacaga ccaacccttt atacttggct aagctgattt tccagatgcc acagaacaag
     2821 tccactaaat ttatggatac tgttattttc acactatata attatgcctc taatcagcga
     2881 gaagaatatc tacttctcaa gctttttaaa actgctctgg aggaagaaat aaaatcaaaa
     2941 gtggaccagg tacaggacat agttactggt aaccctacag tcatcaagat ggtcgtcagc
     3001 ttcaatagag gtgcccgggg acagaacacc ctgcgccaac tcctggctcc agtggtaaaa
     3061 gagatcatcg acgacaagtc gctgattatc aacacaaacc ctgtagaggt gtacaaggct
     3121 tgggtgaacc aactagaaac acagactgga gaggccagca agttgcctta tgatgtgacc
     3181 acagaacaag ctctaacata cccagaagtg aaaaataaac tggaggcttc cattgagaac
     3241 ctgagaaggg tcaccgacaa agtcctgaat tctatcattt cttcccttga tctactgcct
     3301 tatggattga ggtatatagc caaagtactg aagaattcga tccatgagaa attccccgat
     3361 gcaacagaag atgagctatt aaagattgtt ggaaacctcc tgtactatcg gtacatgaat
     3421 ccagccattg tagctccaga tggctttgat atcatcgaca tgacagctgg aggtcagata
     3481 aattctgacc aaaggagaaa cttaggatca gtggccaagg ttcttcagca cgcagcctcc
     3541 aacaagctgt ttgaaggaga aaatgagcat ctctcatcta tgaacaatta tttatcagag
     3601 acgtatcagg aattcaggaa atatttcaaa gaagcatgta atgtccctga gccagaagag
     3661 aagtttaata tggacaaata cacagacctg gtgacagtca gcaaaccagt catttatatt
     3721 tcaattgaag aaatcatcag cacacactca ctcctgttgg aacaccagga tgcaattgcc
     3781 cctgagaaaa atgacttact gagtgaattg ctggggtcgc tgggagaggt gccaaccgtg
     3841 gaatcttttc ttggggaagg agcagttgac cccaatgacc ctaacaaggc aaatacacta
     3901 agtcagcttt caaagaccga gatttctctt gtcttgacaa gcaaatatga catagaggac
     3961 ggtgaagcta tagatagccg aagcctcatg ataaagacca agaagctgat aattgatgtg
     4021 atccggaacc agccagggaa cacattgaca gaaatcttag agacaccagc aactgcgcaa
     4081 caggaggtag accatgccac ggacatggtg agccgtgcaa tgatagattc caggactcca
     4141 gaagaaatga agcatagcca atctatgatt gaagatgcac agctgcctct tgagcagaag
     4201 aagaggaaaa tccagaggaa tcttcggacg ttggaacaga ctggacacgt gtcatccgaa
     4261 aataaatacc aagacattct caatgagatt gccaaggata ttcgaaatca aagaatctat
     4321 cgtaagcttc gaaaagctga attggcaaaa cttcagcaga ccctgaatgc acttaacaag
     4381 aaggcagcat tttatgaaga gcaaatcaat tattatgaca cctacataaa gacttgttta
     4441 gacaacttaa aaagaaaaaa tactcggaga tcaattaaac tagatggaaa aggagaaccc
     4501 aaaggggcga agagagcgaa gccagtgaag tacactgcag caaagctgca tgagaaaggt
     4561 gtcctgctag atatagatga tcttcaaaca aaccagttta agaatgttac atttgatatc
     4621 atagctactg aagatgtagg cattttcgat gtaagatcaa aattccttgg tgttgagatg
     4681 gaaaaggtgc aactcaatat tcaggattta cttcagatgc aatatgaagg agtagctgta
     4741 atgaaaatgt ttgataaggt taaagtgaat gtaaaccttc tcatatacct gctgaacaag
     4801 aagttctatg gaaagtgaag tgcctacaga aatttcttgg attctgtatc atctggatta
     4861 ggaaatgaat ttgtttaata tttttgtttt taaacatgat tgaaatcact gcttataaat
     4921 gtgtgatttt tttaaaacga ccaaaactgt tctgaagaat gtacccaggt gcctttttgc
     4981 taatttgata ctataataga atgagacata aaatgaatta atggaaacat atccacactg
     5041 tactgtgata taggtactct gatttaaaac tttggacatc ctgtgatctg ttttaaagtt
     5101 ggggggtggg aaatttagct gactagggac aaacatgtaa acctattttc ctatgaaaaa
     5161 aattttaaat gtcccacttg aataacgtaa ttcttcatag tttttttaat ctatggataa
     5221 atggaaacct aattatttgt aatgaattat ttagacagtt ctaagccctg tcttctggga
     5281 gttatcaatt ttaaagagaa cttttgtgca attcaaatga agtttttata agtaattgaa
     5341 aatgacaaca caataacact ttctgtataa aagtatatat tttatgtgat ttattcctac
     5401 taaatgaaag tgcactactg cctcatgtaa agactcttgc acgcagagcc tttaagtgac
     5461 taaggaacaa catagatagt gagcatagtc cccacctcca cccctcacaa tttatttgaa
     5521 tacttcaatt gtgcctctca attttttgta atgctaaaaa atcagtatct agatggtttt
     5581 taaatgtatt ctctggaaat tgttttatgt aaaataaatg ttacttaatt ccattaa
//
