LOCUS       XM_011543108            4259 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens IQ motif containing GTPase activating
            protein 2 (IQGAP2), transcript variant X7, mRNA.
ACCESSION   XM_011543108
VERSION     XM_011543108.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000005.10) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011543108.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4259
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
     gene            1..4259
                     /gene="IQGAP2"
                     /note="IQ motif containing GTPase activating protein 2;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 63 ESTs, 813 long SRA reads, 3 Proteins,
                     and 100% coverage of the annotated genomic feature by
                     RNAseq alignments, including 9 samples with support for
                     all annotated introns"
                     /db_xref="GeneID:10788"
                     /db_xref="HGNC:HGNC:6111"
                     /db_xref="MIM:605401"
     CDS             54..3440
                     /gene="IQGAP2"
                     /codon_start=1
                     /product="ras GTPase-activating-like protein IQGAP2
                     isoform X6"
                     /protein_id="XP_011541410.1"
                     /db_xref="GeneID:10788"
                     /db_xref="HGNC:HGNC:6111"
                     /db_xref="MIM:605401"
                     /translation="MHSLPGVVAVGYINEAIDEGNPLRTLETLLLPTANISDVDPAHA
                     QHYQDVLYHAKSQKLGDSESVSKVLWLDEIQQAVDDANVDKDRAKQWVTLVVDVNQCL
                     EGKKSSDILSVLKSSTSNANDIIPECADKYYDALVKAKELKSERVSSDGSWLKLNLHK
                     KYDYYYNTDSKESSWVTPESCLYKESWLTGKEIEDIIEEVTVGYIRENIWSASEELLL
                     RFQATSSGPILREEFEARKSFLHEQEENVVKIQAFWKGYKQRKEYMHRRQTFIDNTDS
                     IVKIQSWFRMATARKSYLSRLQYFRDHNNEIVKIQSLLRANKARDDYKTLVGSENPPL
                     TVIRKFVYLLDQSDLDFQEELEVARLREEVVTKIRANQQLEKDLNLMDIKIGLLVKNR
                     ITLEDVISHSKKLNKKKGGEMEILNNTDNQGIKSLSKERRKTLETYQQLFYLLQTNPL
                     YLAKLIFQMPQNKSTKFMDTVIFTLYNYASNQREEYLLLKLFKTALEEEIKSKVDQVQ
                     DIVTGNPTVIKMVVSFNRGARGQNTLRQLLAPVVKEIIDDKSLIINTNPVEVYKAWVN
                     QLETQTGEASKLPYDVTTEQALTYPEVKNKLEASIENLRRVTDKVLNSIISSLDLLPY
                     GLRYIAKVLKNSIHEKFPDATEDELLKIVGNLLYYRYMNPAIVAPDGFDIIDMTAGGQ
                     INSDQRRNLGSVAKVLQHAASNKLFEGENEHLSSMNNYLSETYQEFRKYFKEACNVPE
                     PEEKFNMDKYTDLVTVSKPVIYISIEEIISTHSLLLEHQDAIAPEKNDLLSELLGSLG
                     EVPTVESFLGEGAVDPNDPNKANTLSQLSKTEISLVLTSKYDIEDGEAIDSRSLMIKT
                     KKLIIDVIRNQPGNTLTEILETPATAQQEVDHATDMVSRAMIDSRTPEEMKHSQSMIE
                     DAQLPLEQKKRKIQRNLRTLEQTGHVSSENKYQDILNEIAKDIRNQRIYRKLRKAELA
                     KLQQTLNALNKKAAFYEEQINYYDTYIKTCLDNLKRKNTRRSIKLDGKGEPKGAKRAK
                     PVKYTAAKLHEKGVLLDIDDLQTNQFKNVTFDIIATEDVGIFDVRSKFLGVEMEKVQL
                     NIQDLLQMQYEGVAVMKMFDKVKVNVNLLIYLLNKKFYGK"
ORIGIN      
        1 agaaacgcag cagacagcaa ctttagcagg tgatttcaat caagtcagct gaaatgcact
       61 cacttccagg agttgtagct gtagggtaca tcaatgaagc tattgatgaa gggaatcctt
      121 tgaggacttt agaaactttg ctcctaccta ctgcgaatat tagtgatgtg gacccagccc
      181 atgcccagca ctaccaggat gttttatacc atgctaaatc acagaaactc ggagactctg
      241 agagtgtttc caaagtgctt tggctggatg agatacagca agccgtcgat gatgccaacg
      301 tggacaagga cagagcaaaa caatgggtta ctctggtggt tgatgttaat cagtgtttgg
      361 aaggaaaaaa atcaagtgat attttgtctg tattgaagtc ttccacttct aatgcaaatg
      421 acataatccc ggagtgtgct gacaaatact atgatgccct tgtgaaggca aaagagctca
      481 aatctgaaag agtgtctagt gacggttcat ggctcaaact caacctgcac aaaaaatatg
      541 actactatta caacactgat tcaaaagaga gttcctgggt cacacctgaa tcatgcttgt
      601 ataaagaatc atggctcaca ggaaaagaaa tcgaggacat tattgaggaa gtcacagtag
      661 gttacattcg tgagaatata tggtctgctt cagaagagtt gcttcttcgc tttcaagcca
      721 caagctcagg acccatcctt agggaagagt ttgaagctag aaaatcattt ttgcatgaac
      781 aagaagagaa tgtggtcaaa atacaggctt tttggaaagg atataaacaa cggaaggagt
      841 atatgcacag gcggcaaacg ttcattgata atactgattc tattgtgaag attcagtcct
      901 ggttccgaat ggcaactgca agaaagagct atctttcaag actacagtat ttcagagatc
      961 ataataatga aattgtgaaa atacagtcac tgttgagagc gaacaaagct agagatgact
     1021 acaaaacatt ggttggctct gaaaacccac cattaacagt aattcgcaaa tttgtatacc
     1081 tgctggacca aagtgatttg gatttccagg aggaactaga ggttgcacga ttaagggaag
     1141 aagtagtgac caagatcagg gccaatcaac agctggaaaa agacctgaac ctgatggaca
     1201 tcaagattgg actgctggtg aagaacagga tcacactaga ggatgtaatt tcacatagta
     1261 aaaagctgaa caagaaaaaa ggaggagaaa tggaaatact gaataacacc gacaaccaag
     1321 gaataaaaag tttgagtaag gagaggagaa aaacactaga aacatatcag cagctgtttt
     1381 accttttaca gaccaaccct ttatacttgg ctaagctgat tttccagatg ccacagaaca
     1441 agtccactaa atttatggat actgttattt tcacactata taattatgcc tctaatcagc
     1501 gagaagaata tctacttctc aagcttttta aaactgctct ggaggaagaa ataaaatcaa
     1561 aagtggacca ggtacaggac atagttactg gtaaccctac agtcatcaag atggtcgtca
     1621 gcttcaatag aggtgcccgg ggacagaaca ccctgcgcca actcctggct ccagtggtaa
     1681 aagagatcat cgacgacaag tcgctgatta tcaacacaaa ccctgtagag gtgtacaagg
     1741 cttgggtgaa ccaactagaa acacagactg gagaggccag caagttgcct tatgatgtga
     1801 ccacagaaca agctctaaca tacccagaag tgaaaaataa actggaggct tccattgaga
     1861 acctgagaag ggtcaccgac aaagtcctga attctatcat ttcttccctt gatctactgc
     1921 cttatggatt gaggtatata gccaaagtac tgaagaattc gatccatgag aaattccccg
     1981 atgcaacaga agatgagcta ttaaagattg ttggaaacct cctgtactat cggtacatga
     2041 atccagccat tgtagctcca gatggctttg atatcatcga catgacagct ggaggtcaga
     2101 taaattctga ccaaaggaga aacttaggat cagtggccaa ggttcttcag cacgcagcct
     2161 ccaacaagct gtttgaagga gaaaatgagc atctctcatc tatgaacaat tatttatcag
     2221 agacgtatca ggaattcagg aaatatttca aagaagcatg taatgtccct gagccagaag
     2281 agaagtttaa tatggacaaa tacacagacc tggtgacagt cagcaaacca gtcatttata
     2341 tttcaattga agaaatcatc agcacacact cactcctgtt ggaacaccag gatgcaattg
     2401 cccctgagaa aaatgactta ctgagtgaat tgctggggtc gctgggagag gtgccaaccg
     2461 tggaatcttt tcttggggaa ggagcagttg accccaatga ccctaacaag gcaaatacac
     2521 taagtcagct ttcaaagacc gagatttctc ttgtcttgac aagcaaatat gacatagagg
     2581 acggtgaagc tatagatagc cgaagcctca tgataaagac caagaagctg ataattgatg
     2641 tgatccggaa ccagccaggg aacacattga cagaaatctt agagacacca gcaactgcgc
     2701 aacaggaggt agaccatgcc acggacatgg tgagccgtgc aatgatagat tccaggactc
     2761 cagaagaaat gaagcatagc caatctatga ttgaagatgc acagctgcct cttgagcaga
     2821 agaagaggaa aatccagagg aatcttcgga cgttggaaca gactggacac gtgtcatccg
     2881 aaaataaata ccaagacatt ctcaatgaga ttgccaagga tattcgaaat caaagaatct
     2941 atcgtaagct tcgaaaagct gaattggcaa aacttcagca gaccctgaat gcacttaaca
     3001 agaaggcagc attttatgaa gagcaaatca attattatga cacctacata aagacttgtt
     3061 tagacaactt aaaaagaaaa aatactcgga gatcaattaa actagatgga aaaggagaac
     3121 ccaaaggggc gaagagagcg aagccagtga agtacactgc agcaaagctg catgagaaag
     3181 gtgtcctgct agatatagat gatcttcaaa caaaccagtt taagaatgtt acatttgata
     3241 tcatagctac tgaagatgta ggcattttcg atgtaagatc aaaattcctt ggtgttgaga
     3301 tggaaaaggt gcaactcaat attcaggatt tacttcagat gcaatatgaa ggagtagctg
     3361 taatgaaaat gtttgataag gttaaagtga atgtaaacct tctcatatac ctgctgaaca
     3421 agaagttcta tggaaagtga agtgcctaca gaaatttctt ggattctgta tcatctggat
     3481 taggaaatga atttgtttaa tatttttgtt tttaaacatg attgaaatca ctgcttataa
     3541 atgtgtgatt tttttaaaac gaccaaaact gttctgaaga atgtacccag gtgccttttt
     3601 gctaatttga tactataata gaatgagaca taaaatgaat taatggaaac atatccacac
     3661 tgtactgtga tataggtact ctgatttaaa actttggaca tcctgtgatc tgttttaaag
     3721 ttggggggtg ggaaatttag ctgactaggg acaaacatgt aaacctattt tcctatgaaa
     3781 aaaattttaa atgtcccact tgaataacgt aattcttcat agttttttta atctatggat
     3841 aaatggaaac ctaattattt gtaatgaatt atttagacag ttctaagccc tgtcttctgg
     3901 gagttatcaa ttttaaagag aacttttgtg caattcaaat gaagttttta taagtaattg
     3961 aaaatgacaa cacaataaca ctttctgtat aaaagtatat attttatgtg atttattcct
     4021 actaaatgaa agtgcactac tgcctcatgt aaagactctt gcacgcagag cctttaagtg
     4081 actaaggaac aacatagata gtgagcatag tccccacctc cacccctcac aatttatttg
     4141 aatacttcaa ttgtgcctct caattttttg taatgctaaa aaatcagtat ctagatggtt
     4201 tttaaatgta ttctctggaa attgttttat gtaaaataaa tgttacttaa ttccattaa
//
