LOCUS       NM_001378182            1829 bp    mRNA    linear   PRI 12-OCT-2024
DEFINITION  Homo sapiens IQ motif containing M (IQCM), transcript variant 8,
            mRNA.
ACCESSION   NM_001378182 XM_024454314
VERSION     NM_001378182.1
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1829)
  AUTHORS   Eriksson,N., Tung,J.Y., Kiefer,A.K., Hinds,D.A., Francke,U.,
            Mountain,J.L. and Do,C.B.
  TITLE     Novel associations for hypothyroidism include known autoimmune risk
            loci
  JOURNAL   PLoS One 7 (4), e34442 (2012)
   PUBMED   22493691
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC096756.3, AC093893.2, AC027058.9 and AC108168.4.
            
            On Jan 30, 2020 this sequence version replaced XM_024454314.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.234563.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2151119
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-244               AC096756.3         20407-20650         c
            245-282             AC096756.3         20118-20155         c
            283-345             AC093893.2         151804-151866       c
            346-430             AC093893.2         145766-145850       c
            431-513             AC093893.2         138487-138569       c
            514-778             AC093893.2         136355-136619       c
            779-867             AC093893.2         85229-85317         c
            868-983             AC093893.2         24240-24355         c
            984-1022            AC093893.2         13168-13206         c
            1023-1090           AC027058.9         8354-8421
            1091-1289           AC027058.9         32461-32659
            1290-1434           AC027058.9         43064-43208
            1435-1569           AC027058.9         47762-47896
            1570-1731           AC108168.4         59347-59508         c
            1732-1829           AC108168.4         55883-55980         c
FEATURES             Location/Qualifiers
     source          1..1829
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
                     /map="4q31.23"
     gene            1..1829
                     /gene="IQCM"
                     /note="IQ motif containing M"
                     /db_xref="GeneID:285423"
                     /db_xref="HGNC:HGNC:53443"
     exon            1..244
                     /gene="IQCM"
                     /inference="alignment:Splign:2.1.0"
     exon            245..282
                     /gene="IQCM"
                     /inference="alignment:Splign:2.1.0"
     exon            283..345
                     /gene="IQCM"
                     /inference="alignment:Splign:2.1.0"
     exon            346..430
                     /gene="IQCM"
                     /inference="alignment:Splign:2.1.0"
     exon            431..513
                     /gene="IQCM"
                     /inference="alignment:Splign:2.1.0"
     exon            514..778
                     /gene="IQCM"
                     /inference="alignment:Splign:2.1.0"
     CDS             750..1787
                     /gene="IQCM"
                     /note="isoform 8 is encoded by transcript variant 8; iQ
                     domain-containing protein M"
                     /codon_start=1
                     /product="IQ domain-containing protein M isoform 8"
                     /protein_id="NP_001365111.1"
                     /db_xref="GeneID:285423"
                     /db_xref="HGNC:HGNC:53443"
                     /translation="MQAHRSNYKRNRMLELLYPFPVHLYLQPGTSNLELLKEPDKAFY
                     DWRGFVLTRSFRLACDSRRVSFSQSSSIFRDYYSIVCSWHINMLLIFKTFKTLIKKER
                     QPIKPEPKSQPRIKGTPNKTDKLDSKVKRIGPHIEIFQVFRERKKFMITPKLIRMVTV
                     MQAHVRGWLERKRLQRVMTKALDHGPDMKAVINMYGRLIHRVRYRRGLWRTRQILNLA
                     ELEEWMDRKKFYEIMFAKREDWPKIERNELPNFFSDCGHFPTQKQVDDTWDLVHQDGK
                     EKYSELIKKSKAIEMLFTLYPPEGAHVPDSTLLKSTWLRPIVNGEEGYRYIVFHLKLS
                     EGDLYLFVFVV"
     exon            779..867
                     /gene="IQCM"
                     /inference="alignment:Splign:2.1.0"
     exon            868..983
                     /gene="IQCM"
                     /inference="alignment:Splign:2.1.0"
     exon            984..1022
                     /gene="IQCM"
                     /inference="alignment:Splign:2.1.0"
     exon            1023..1090
                     /gene="IQCM"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1289
                     /gene="IQCM"
                     /inference="alignment:Splign:2.1.0"
     exon            1290..1434
                     /gene="IQCM"
                     /inference="alignment:Splign:2.1.0"
     exon            1435..1569
                     /gene="IQCM"
                     /inference="alignment:Splign:2.1.0"
     exon            1570..1731
                     /gene="IQCM"
                     /inference="alignment:Splign:2.1.0"
     exon            1732..1829
                     /gene="IQCM"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaagaagaca ggcatatgtg agaagaagca atcagaagat tggcaggatt taggaatcta
       61 tttgaaatat tcattaccta ttttgaattg gtcttaaaaa tttaaagaaa tataaagctg
      121 gataattaaa gataaataat aaaggaagaa tacaaggttt ctatgctgtg aagcaactga
      181 gattattatg attttggggc agtgaatttg tttctagaag ttttgttgga actaaggcag
      241 aaaggaagaa gaacaaatga ccttggaatg aaaaacttta agttactcca cctaaccact
      301 atgaatgata gtcttgtctc accaacccca gcccatcatc tgttggactt ggagctcaca
      361 ctttaaaaaa gaagatcatt ctaactgccc ctcatgacta ctgaagaggc tatgcctgaa
      421 aaagcaaaat gtcctacatt agagatcacc aagcaagact tttttcaaga agcaaaaact
      481 ctcattgccc aacattatga gaaaataaat gagaataaag ttcaaggtac ttctataaat
      541 gtttttagaa agaaacacca aaaaccgaaa tctggcaaat acataccttt ggagattgac
      601 aaaaaggtaa cacgtgatgt ggtgcaagaa catcgggccg cactcagaag gatttgcttt
      661 cccaaggagc tttccaaaag cgagcatctt caggaacccc cacaacgaat ctccttcaag
      721 gaaccacaca tttttagtag aagagaaaga tgcaggccca tagatctaat tacaaaagaa
      781 acagaatgtt ggaattactc tatccctttc ctgtccatct ttacttacaa cctgggacct
      841 ctaacttgga acttctgaaa gaacctgaca aagcattcta tgactggaga ggatttgtgc
      901 tgacaaggtc tttccgtttg gcttgtgact cccgtcgagt tagtttctct caatcatcat
      961 caatatttcg ggattattat tctattgttt gcagttggca tataaacatg ctactgattt
     1021 tcaaaacctt taaaaccctt attaaaaagg agcgacaacc tatcaagcca gaaccaaaat
     1081 cacaacccag gataaaaggt actccaaata aaactgataa acttgacagt aaagttaaaa
     1141 gaattggacc acacatagaa atcttccaag tgttccgaga aagaaaaaaa ttcatgatta
     1201 ccccaaaatt gattagaatg gtcaccgtca tgcaggcaca tgtcagggga tggcttgaac
     1261 ggaaaagatt gcaaagagta atgaccaagg ctttggatca tggaccagat atgaaagcag
     1321 ttattaacat gtatggcaga ctaatccacc gtgttagata tcgacgtggt ctttggagga
     1381 caagacaaat tctcaactta gcagagctag aggagtggat ggaccgaaaa aaattctatg
     1441 aaataatgtt tgctaagagg gaagattggc caaaaattga aagaaatgag ctccccaatt
     1501 tcttcagtga ctgtggtcat ttcccaactc agaaacaagt tgatgatact tgggacctgg
     1561 tccatcaaga tggcaaagaa aaatattctg aactaatcaa aaagtccaaa gcaattgaaa
     1621 tgttatttac actctatcct cctgaaggtg cacatgtgcc tgacagtaca ctactcaagt
     1681 cgacttggtt gagacccata gtaaatgggg aagaaggtta tagatatata gttttccacc
     1741 tgaaattatc agaaggtgac ctatatctat ttgtgtttgt tgtttagagt ctatttgcac
     1801 tttgttaaaa taaacaaatt aaaaggaaa
//
