LOCUS       NM_001145059             529 bp    mRNA    linear   PRI 09-FEB-2024
DEFINITION  Homo sapiens IQ motif containing F5 (IQCF5), mRNA.
ACCESSION   NM_001145059 XM_001723363 XM_371643 XM_942552
VERSION     NM_001145059.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 529)
  AUTHORS   Xie,T., Deng,L., Mei,P., Zhou,Y., Wang,B., Zhang,J., Lin,J.,
            Wei,Y., Zhang,X. and Xu,R.
  TITLE     Genome-wide association study combining pathway analysis for
            typical sporadic amyotrophic lateral sclerosis in Chinese Han
            populations
  JOURNAL   Neurobiol Aging 35 (7), 1778 (2014)
   PUBMED   24529757
REFERENCE   2  (bases 1 to 529)
  AUTHORS   Muzny,D.M., Scherer,S.E., Kaul,R., Wang,J., Yu,J., Sudbrak,R.,
            Buhay,C.J., Chen,R., Cree,A., Ding,Y., Dugan-Rocha,S., Gill,R.,
            Gunaratne,P., Harris,R.A., Hawes,A.C., Hernandez,J., Hodgson,A.V.,
            Hume,J., Jackson,A., Khan,Z.M., Kovar-Smith,C., Lewis,L.R.,
            Lozado,R.J., Metzker,M.L., Milosavljevic,A., Miner,G.R.,
            Morgan,M.B., Nazareth,L.V., Scott,G., Sodergren,E., Song,X.Z.,
            Steffen,D., Wei,S., Wheeler,D.A., Wright,M.W., Worley,K.C.,
            Yuan,Y., Zhang,Z., Adams,C.Q., Ansari-Lari,M.A., Ayele,M.,
            Brown,M.J., Chen,G., Chen,Z., Clendenning,J.,
            Clerc-Blankenburg,K.P., Chen,R., Chen,Z., Davis,C., Delgado,O.,
            Dinh,H.H., Dong,W., Draper,H., Ernst,S., Fu,G.,
            Gonzalez-Garay,M.L., Garcia,D.K., Gillett,W., Gu,J., Hao,B.,
            Haugen,E., Havlak,P., He,X., Hennig,S., Hu,S., Huang,W.,
            Jackson,L.R., Jacob,L.S., Kelly,S.H., Kube,M., Levy,R., Li,Z.,
            Liu,B., Liu,J., Liu,W., Lu,J., Maheshwari,M., Nguyen,B.V.,
            Okwuonu,G.O., Palmeiri,A., Pasternak,S., Perez,L.M., Phelps,K.A.,
            Plopper,F.J., Qiang,B., Raymond,C., Rodriguez,R.,
            Saenphimmachak,C., Santibanez,J., Shen,H., Shen,Y., Subramanian,S.,
            Tabor,P.E., Verduzco,D., Waldron,L., Wang,J., Wang,J., Wang,Q.,
            Williams,G.A., Wong,G.K., Yao,Z., Zhang,J., Zhang,X., Zhao,G.,
            Zhou,J., Zhou,Y., Nelson,D., Lehrach,H., Reinhardt,R., Naylor,S.L.,
            Yang,H., Olson,M., Weinstock,G. and Gibbs,R.A.
  TITLE     The DNA sequence, annotation and analysis of human chromosome 3
  JOURNAL   Nature 440 (7088), 1194-1198 (2006)
   PUBMED   16641997
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC097636.2, BX106781.1 and AW138546.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001145059.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BX106781.1, SRR5189667.312543.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000446461.2/ ENSP00000394653.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-17                AC097636.2         92689-92705         c
            18-500              BX106781.1         1-483
            501-529             AW138546.1         17-45               c
FEATURES             Location/Qualifiers
     source          1..529
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p21.2"
     gene            1..529
                     /gene="IQCF5"
                     /note="IQ motif containing F5"
                     /db_xref="GeneID:389124"
                     /db_xref="HGNC:HGNC:35159"
     exon            1..74
                     /gene="IQCF5"
                     /inference="alignment:Splign:2.1.0"
     CDS             71..517
                     /gene="IQCF5"
                     /codon_start=1
                     /product="IQ domain-containing protein F5"
                     /protein_id="NP_001138531.1"
                     /db_xref="CCDS:CCDS46838.1"
                     /db_xref="GeneID:389124"
                     /db_xref="HGNC:HGNC:35159"
                     /translation="MGPEEKTIMTERSAAVFIQAWWRGMLVRRTLLHAALRAWIIQCW
                     WRQVLEKLLAKRRRMVLEFYVQQEWAAVRLQSWVRMWCVRQRYCRLLNAVRIIQVYWR
                     WHSCHSRVFIEGHYELKENQLNIQLEISLGLQACKVQQCIPLPLKE"
     exon            75..529
                     /gene="IQCF5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      505..510
                     /regulatory_class="polyA_signal_sequence"
                     /gene="IQCF5"
                     /note="hexamer: ATTAAA"
     polyA_site      529
                     /gene="IQCF5"
                     /note="major polyA site"
ORIGIN      
        1 actcttcctg ttggagtcct gatcggagga gtgcgggccg gagggtgatg ggaccatcta
       61 gcccctaacc atgggcccag aagagaagac catcatgaca gaaaggtctg cagctgtttt
      121 catccaggcc tggtggcggg gcatgctggt gcgacgcaca ctgctgcatg cagccctcag
      181 ggcttggatc attcagtgct ggtggaggca ggtgctggag aagctgctgg caaagaggcg
      241 gaggatggtg ttggagttct atgtgcagca ggaatgggca gcagtcaggc tgcagtcctg
      301 ggtccgcatg tggtgtgtcc gccagcgtta ctgtcgtttg ctcaacgctg tccgcatcat
      361 ccaggtctat tggcgctggc acagctgcca ttcccgtgtc tttattgagg gccactatga
      421 actcaaagaa aaccaactta atattcaact tgaaatctct ttgggcttac aggcttgtaa
      481 ggtgcaacaa tgcatacccc ttccattaaa agaatgacca ggtctgcta
//
