LOCUS       NM_001393887             570 bp    mRNA    linear   PRI 12-JUN-2024
DEFINITION  Homo sapiens IQ motif containing F3 (IQCF3), transcript variant 3,
            mRNA.
ACCESSION   NM_001393887
VERSION     NM_001393887.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 570)
  AUTHORS   Xu,Y., Yang,X.L., Yang,X.L., Ren,Y.R., Zhuang,X.Y., Zhang,L. and
            Zhang,X.F.
  TITLE     Functional Annotations of Single-Nucleotide Polymorphism
            (SNP)-Based and Gene-Based Genome-Wide Association Studies Show
            Genes Affecting Keratitis Susceptibility
  JOURNAL   Med Sci Monit 26, e922710 (2020)
   PUBMED   32450567
  REMARK    GeneRIF: Functional Annotations of Single-Nucleotide Polymorphism
            (SNP)-Based and Gene-Based Genome-Wide Association Studies Show
            Genes Affecting Keratitis Susceptibility.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 570)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC097636.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DB336135.1, AA453974.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2148093
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000440739.4/ ENSP00000402012.2
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-68                AC097636.2         46530-46597
            69-116              AC097636.2         46769-46816
            117-570             AC097636.2         47507-47960
FEATURES             Location/Qualifiers
     source          1..570
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p21.2"
     gene            1..570
                     /gene="IQCF3"
                     /note="IQ motif containing F3"
                     /db_xref="GeneID:401067"
                     /db_xref="HGNC:HGNC:31816"
     exon            1..68
                     /gene="IQCF3"
                     /inference="alignment:Splign:2.1.0"
     CDS             51..515
                     /gene="IQCF3"
                     /codon_start=1
                     /product="IQ domain-containing protein F3"
                     /protein_id="NP_001380816.1"
                     /db_xref="CCDS:CCDS46837.1"
                     /db_xref="GeneID:401067"
                     /db_xref="HGNC:HGNC:31816"
                     /translation="MGSKCCKGGPDEDAVERQRRQKLLLAQLHHRKRVKAAGQIQAWW
                     RGVLVRRTLLVAALRAWMIQCWWRTLVQRRIRQRRQALLRVYVIQEQATVKLQSCIRM
                     WQCRQCYRQMCNALCLFQVPESSLAFQTDGFLQVQYAIPSKQPEFHIEILSI"
     exon            69..116
                     /gene="IQCF3"
                     /inference="alignment:Splign:2.1.0"
     exon            117..570
                     /gene="IQCF3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      552..557
                     /regulatory_class="polyA_signal_sequence"
                     /gene="IQCF3"
                     /note="hexamer: AATAAA"
     polyA_site      570
                     /gene="IQCF3"
                     /note="major polyA site"
ORIGIN      
        1 aggaaacagc aaccagaggg agatgatcac ctgaaccact gctccaaacc atgggcagta
       61 aatgctgtaa aggtggtcca gatgaagatg cagtagaaag acagaggcgg cagaagttgc
      121 ttcttgcaca actgcatcac agaaaaaggg tgaaggcagc tgggcagatc caggcctggt
      181 ggcgtggggt cctggtgcgc aggaccctgc tggttgctgc cctcagggcc tggatgattc
      241 agtgctggtg gaggacgttg gtgcagagac ggatccgtca gcggcggcag gccctgttga
      301 gggtctacgt catccaggag caggcgacgg tcaagctcca gtcctgcatc cgcatgtggc
      361 agtgccggca atgttaccgc caaatgtgca atgctctctg cttgttccag gtcccagaga
      421 gcagccttgc cttccagact gatggctttt tacaggtcca atatgcaatc ccttcaaagc
      481 agccagagtt ccacattgaa atcctatcaa tctgaaaggc ctggggcatg gagaacaggc
      541 tgcactaccc taataaatgt ctgaccaggt
//
