LOCUS       XM_047444183            5245 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens interleukin 1 receptor type 1 (IL1R1),
            transcript variant X13, mRNA.
ACCESSION   XM_047444183
VERSION     XM_047444183.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5245
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..5245
                     /gene="IL1R1"
                     /gene_synonym="CD121A; CRMO3; D2S1473; IL-1R-alpha;
                     IL-1RT1; IL1R; IL1RA; P80"
                     /note="interleukin 1 receptor type 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 25
                     ESTs, 446 long SRA reads, 4 Proteins, and 97% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 64 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:3554"
                     /db_xref="HGNC:HGNC:5993"
                     /db_xref="MIM:147810"
     CDS             853..2130
                     /gene="IL1R1"
                     /gene_synonym="CD121A; CRMO3; D2S1473; IL-1R-alpha;
                     IL-1RT1; IL1R; IL1RA; P80"
                     /codon_start=1
                     /product="interleukin-1 receptor type 1 isoform X2"
                     /protein_id="XP_047300139.1"
                     /db_xref="GeneID:3554"
                     /db_xref="HGNC:HGNC:5993"
                     /db_xref="MIM:147810"
                     /translation="MEFFKNENNELPKLQWYKDCKPLLLDNIHFSGVKDRLIVMNVAE
                     KHRGNYTCHASYTYLGKQYPITRVIEFITLEENKPTRPVIVSPANETMEVDLGSQIQL
                     ICNVTGQLSDIAYWKWNGSVIDEDDPVLGEDYYSVENPANKRRSTLITVLNISEIESR
                     FYKHPFTCFAKNTHGIDAAYIQLIYPVTNFQKHMIGICVTLTVIIVCSVFIYKIFKID
                     IVLWYRDSCYDFLPIKASDGKTYDAYILYPKTVGEGSTSDCDIFVFKVLPEVLEKQCG
                     YKLFIYGRDDYVGEDIVEVINENVKKSRRLIIILVRETSGFSWLGGSSEEQIAMYNAL
                     VQDGIKVVLLELEKIQDYEKMPESIKFIKQKHGAIRWSGDFTQGPQSAKTRFWKNVRY
                     HMPVQRRSPSSKHQLLSPATKEKLQREAHVPLG"
ORIGIN      
        1 agttcccggc cgcgagggcg ggcgcagctt gtggccggcg gccggagccg actcggagcg
       61 cgcggcgccg gccgggagga gccggagagc ggccgggccg ggcggtgggg gcgccggcct
      121 gccccgcgcg ccccagggag cggcaggaat gtgacaatcg cgcgcccgcg caccgaagca
      181 ctcctcgctc ggctcctagg gctctcgccc ctctgagctg agccgggttc cgcccggggc
      241 tgggatccca tcaccctcca cggccgtccg tccaggtaga cgcaccctct gaagatggtg
      301 actccctcct gagaagctgg accccttggt aaaagacaag gccttctcca agaatatgaa
      361 agtgttactc agacttattt gtttcatagc tctactgatt tcttctctgg aggctgatat
      421 taaatcaaga cacactggca gatttttatg taaattgctt ccacccttct tccttttaaa
      481 gataaatgca aggaacgtga agaaaaaata attttagtgt catctgcaaa tgaaattgat
      541 gttcgtccct gtcctcttaa cccaaatgaa cacaaaggca ctataacttg gtataaagat
      601 gacagcaaga cacctgtatc tacagaacaa gcctccagga ttcatcaaca caaagagaaa
      661 ctttggtttg ttcctgctaa ggtggaggat tcaggacatt actattgcgt ggtaagaaat
      721 tcatcttact gcctcagaat taaaataagt gcaaaatttg tggagaatga gcctaactta
      781 tgttataatg cacaagccat atttaagcag aaactacccg ttgcaggaga cggaggactt
      841 gtgtgccctt atatggagtt ttttaaaaat gaaaataatg agttacctaa attacagtgg
      901 tataaggatt gcaaacctct acttcttgac aatatacact ttagtggagt caaagatagg
      961 ctcatcgtga tgaatgtggc tgaaaagcat agagggaact atacttgtca tgcatcctac
     1021 acatacttgg gcaagcaata tcctattacc cgggtaatag aatttattac tctagaggaa
     1081 aacaaaccca caaggcctgt gattgtgagc ccagctaatg agacaatgga agtagacttg
     1141 ggatcccaga tacaattgat ctgtaatgtc accggccagt tgagtgacat tgcttactgg
     1201 aagtggaatg ggtcagtaat tgatgaagat gacccagtgc taggggaaga ctattacagt
     1261 gtggaaaatc ctgcaaacaa aagaaggagt accctcatca cagtgcttaa tatatcggaa
     1321 attgaaagta gattttataa acatccattt acctgttttg ccaagaatac acatggtata
     1381 gatgcagcat atatccagtt aatatatcca gtcactaatt tccagaagca catgattggt
     1441 atatgtgtca cgttgacagt cataattgtg tgttctgttt tcatctataa aatcttcaag
     1501 attgacattg tgctttggta cagggattcc tgctatgatt ttctcccaat aaaagcttca
     1561 gatggaaaga cctatgacgc atatatactg tatccaaaga ctgttgggga agggtctacc
     1621 tctgactgtg atatttttgt gtttaaagtc ttgcctgagg tcttggaaaa acagtgtgga
     1681 tataagctgt tcatttatgg aagggatgac tacgttgggg aagacattgt tgaggtcatt
     1741 aatgaaaacg taaagaaaag cagaagactg attatcattt tagtcagaga aacatcaggc
     1801 ttcagctggc tgggtggttc atctgaagag caaatagcca tgtataatgc tcttgttcag
     1861 gatggaatta aagttgtcct gcttgagctg gagaaaatcc aagactatga gaaaatgcca
     1921 gaatcgatta aattcattaa gcagaaacat ggggctatcc gctggtcagg ggactttaca
     1981 cagggaccac agtctgcaaa gacaaggttc tggaagaatg tcaggtacca catgccagtc
     2041 cagcgacggt caccttcatc taaacaccag ttactgtcac cagccactaa ggagaaactg
     2101 caaagagagg ctcacgtgcc tctcgggtag catggagaag ttgccaagag ttctttaggt
     2161 gcctcctgtc ttatggcgtt gcaggccagg ttatgcctca tgctgacttg cagagttcat
     2221 ggaatgtaac tatatcatcc tttatccctg aggtcacctg gaatcagatt attaagggaa
     2281 taagccatga cgtcaatagc agcccagggc acttcagagt agagggcttg ggaagatctt
     2341 ttaaaaaggc agtaggcccg gtgtggtggc tcacgcctat aatcccagca ctttgggagg
     2401 ctgaagtggg tggatcacca gaggtcagga gttcgagacc agcccagcca acatggcaaa
     2461 accccatctc tactaaaaat acaaaaatga gctaggcatg gtggcacacg cctgtaatcc
     2521 cagctacacc tgaggctgag gcaggagaat tgcttgaacc ggggagacgg aggttgcagt
     2581 gagccgagtt tgggccactg cactctagcc tggcaacaga gcaagactcc gtctcaaaaa
     2641 aagggcaata aatgccctct ctgaatgttt gaactgccaa gaaaaggcat ggagacagcg
     2701 aactagaaga aagggcaaga aggaaatagc caccgtctac agatggctta gttaagtcat
     2761 ccacagccca agggcggggc tatgccttgt ctggggaccc tgtagagtca ctgaccctgg
     2821 agcggctctc ctgagaggtg ctgcaggcaa agtgagactg acacctcact gaggaaggga
     2881 gacatattct tggagaactt tccatctgct tgtattttcc atacacatcc ccagccagaa
     2941 gttagtgtcc gaagaccgaa ttttatttta cagagcttga aaactcactt caatgaacaa
     3001 agggattctc caggattcca aagttttgaa gtcatcttag ctttccacag gagggagaga
     3061 acttaaaaaa gcaacagtag cagggaattg atccacttct taatgctttc ctccctggca
     3121 tgaccatcct gtcctttgtt attatcctgc attttacgtc tttggaggaa cagctcccta
     3181 gtggcttcct ccgtctgcaa tgtcccttgc acagcccaca catgaaccat ccttcccatg
     3241 atgccgctct tctgtcatcc cgctcctgct gaaacacctc ccaggggctc cacctgttca
     3301 ggagctgaag cccatgcttt cccaccagca tgtcactccc agaccacctc cctgccctgt
     3361 cctccagctt cccctcgctg tcctgctgtg tgaattccca ggttggcctg gtggccatgt
     3421 cgcctgcccc cagcactcct ctgtctctgc tcttgcctgc acccttcctc ctcctttgcc
     3481 taggaggcct tctcgcattt tctctagctg atcagaattt taccaaaatt cagaacatcc
     3541 tccaattcca cagtctctgg gagactttcc ctaagaggcg acttcctctc cagccttctc
     3601 tctctggtca ggcccactgc agagatggtg gtgagcacat ctgggaggct ggtctccctc
     3661 cagctggaat tgctgctctc tgagggagag gctgtggtgg ctgtctctgt ccctcactgc
     3721 cttccaggag caatttgcac atgtaacata gatttatgta atgctttatg tttaaaaaca
     3781 ttccccaatt atcttattta atttttgcaa ttattctaat tttatatata gagaaagtga
     3841 cctatttttt aaaaaaatca cactctaagt tctattgaac ctaggacttg agcctccatt
     3901 tctggcttct agtctggtgt tctgagtact tgatttcagg tcaataacgg tcccccctca
     3961 ctccacactg gcacgtttgt gagaagaaat gacattttgc taggaagtga ccgagtctag
     4021 gaatgctttt attcaagaca ccaaattcca aacttctaaa tgttggaatt ttcaaaaatt
     4081 gtgtttagat tttatgaaaa actcttctac tttcatctat tctttcccta gaggcaaaca
     4141 tttcttaaaa tgtttcattt tcattaaaaa tgaaagccaa atttatatgc caccgattgc
     4201 aggacacaag cacagtttta agagttgtat gaacatggag aggacttttg gtttttatat
     4261 ttctcgtatt taatatgggt gaacaccaac ttttatttgg aataataatt ttcctcctaa
     4321 acaaaaacac attgagttta agtctctgac tcttgccttt ccacctgctt tctcctgggc
     4381 ccgctttgcc tgcttgaagg aacagtgctg ttctggagct gctgttccaa cagacagggc
     4441 ctagctttca tttgacacac agactacagc cagaagccca tggagcaggg atgtcacgtc
     4501 ttgaaaagcc tattagatgt tttacaaatt taattttgca gattatttta gtctgtcatc
     4561 cagaaaatgt gtcagcatgc atagtgctaa gaaagcaagc caatttggaa acttaggtta
     4621 gtgacaaaat tggccagaga gtgggggtga tgatgaccaa gaattacaag tagaatggca
     4681 gctggaattt aaggagggac aagaatcaat ggataagcgt gggtggagga agatccaaac
     4741 agaaaagtgc aaagttattc cccatcttcc aagggttgaa ttctggagga agaagacaca
     4801 ttcctagttc cccgtgaact tcctttgact tattgtcccc actaaaacaa aacaaaaaac
     4861 ttttaatgcc ttccacatta attagatttt cttgcagttt ttttatggca tttttttaaa
     4921 gatgccctaa gtgttgaaga agagtttgca aatgcaacaa aatatttaat taccggttgt
     4981 taaaactggt ttagcacaat ttatattttc cctctcttgc ctttcttatt tgcaataaaa
     5041 ggtattgagc cattttttaa atgacatttt tgataaatta tgtttgtact agttgatgaa
     5101 ggagtttttt ttaacctgtt tatataattt tgcagcagaa gccaaatttt ttgtatatta
     5161 aagcaccaaa ttcatgtaca gcatgcatca cggatcaata gactgtactt attttccaat
     5221 aaaattttca aactttgtac tgtta
//
