LOCUS       XM_047419750            5682 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens IKAROS family zinc finger 1 (IKZF1),
            transcript variant X44, mRNA.
ACCESSION   XM_047419750
VERSION     XM_047419750.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000007.14) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5682
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
     gene            1..5682
                     /gene="IKZF1"
                     /gene_synonym="CVID13; Hs.54452; IK1; IKAROS; LyF-1; LYF1;
                     PPP1R92; PRO0758; ZNFN1A1"
                     /note="IKAROS family zinc finger 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 10 ESTs, 682 long SRA reads, 3 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 25 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:10320"
                     /db_xref="HGNC:HGNC:13176"
                     /db_xref="MIM:603023"
     CDS             66..1208
                     /gene="IKZF1"
                     /gene_synonym="CVID13; Hs.54452; IK1; IKAROS; LyF-1; LYF1;
                     PPP1R92; PRO0758; ZNFN1A1"
                     /codon_start=1
                     /product="DNA-binding protein Ikaros isoform X31"
                     /protein_id="XP_047275706.1"
                     /db_xref="GeneID:10320"
                     /db_xref="HGNC:HGNC:13176"
                     /db_xref="MIM:603023"
                     /translation="MDADEGQDMSQVSGKESPPVSDTPDEGDEPMPIPEDLSTTSGGQ
                     QSSKSDRVVGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYACRRRDALT
                     GHLRTHSVIKEETNHSEMAEDLCKIGSERSLVLDRLASNVAKRDKGLSDTPYDSSASY
                     EKENEMMKSHVMDQAINNAINYLGAESLRPLVQTPPGGSEVVPVISPMYQLHKPLAEG
                     TPRSNHSAQDSAVENLLLLSKAKLVPSEREASPSNSCQDSTDTESNNEEQRSGLIYLT
                     NHIAPHARNGLSLKEEHRAYDLLRAASENSQDALRVVSTSGEQMKVYKCEHCRVLFLD
                     HVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRFHMS"
ORIGIN      
        1 gagcgggccc ggcgcgggcg agcgggctgc agccggcggc ggcgccagca gataacctga
       61 ggaccatgga tgctgatgag ggtcaagaca tgtcccaagt ttcagggaag gaaagccccc
      121 ctgtaagcga tactccagat gagggcgatg agcccatgcc gatccccgag gacctctcca
      181 ccacctcggg aggacagcaa agctccaaga gtgacagagt cgtgggagaa cggcccttcc
      241 agtgcaatca gtgcggggcc tcattcaccc agaagggcaa cctgctccgg cacatcaagc
      301 tgcattccgg ggagaagccc ttcaaatgcc acctctgcaa ctacgcctgc cgccggaggg
      361 acgccctcac tggccacctg aggacgcact ccgtcattaa agaagaaact aatcacagtg
      421 aaatggcaga agacctgtgc aagataggat cagagagatc tctcgtgctg gacagactag
      481 caagtaacgt cgccaaacgg gacaagggcc tgtccgacac gccctacgac agcagcgcca
      541 gctacgagaa ggagaacgaa atgatgaagt cccacgtgat ggaccaagcc atcaacaacg
      601 ccatcaacta cctgggggcc gagtccctgc gcccgctggt gcagacgccc ccgggcggtt
      661 ccgaggtggt cccggtcatc agcccgatgt accagctgca caagccgctc gcggagggca
      721 ccccgcgctc caaccactcg gcccaggaca gcgccgtgga gaacctgctg ctgctctcca
      781 aggccaagtt ggtgccctcg gagcgcgagg cgtccccgag caacagctgc caagactcca
      841 cggacaccga gagcaacaac gaggagcagc gcagcggtct catctacctg accaaccaca
      901 tcgccccgca cgcgcgcaac gggctgtcgc tcaaggagga gcaccgcgcc tacgacctgc
      961 tgcgcgccgc ctccgagaac tcgcaggacg cgctccgcgt ggtcagcacc agcggggagc
     1021 agatgaaggt gtacaagtgc gaacactgcc gggtgctctt cctggatcac gtcatgtaca
     1081 ccatccacat gggctgccac ggcttccgtg atccttttga gtgcaacatg tgcggctacc
     1141 acagccagga ccggtacgag ttctcgtcgc acataacgcg aggggagcac cgcttccaca
     1201 tgagctaaag ccctcccgcg cccccacccc agaccccgag ccaccccagg aaaagcacaa
     1261 ggactgccgc cttctcgctc ccgccagcag catagactgg actggaccag acaatgttgt
     1321 gtttggattt gtaactgttt tttgtttttt gtttgagttg gttgattggg gtttgatttg
     1381 cttttgaaaa gatttttatt tttagaggca gggctgcatt gggagcatcc agaactgcta
     1441 ccttcctaga tgtttcccca gaccgctggc tgagattccc tcacctgtcg cttcctagaa
     1501 tccccttctc caaacgatta gtctaaattt tcagagagaa atagataaaa cacgccacag
     1561 cctgggaagg agcgtgctct accctgtgct aagcacgggg ttcgcgcacc aggtgtcttt
     1621 ttccagtccc cagaagcaga gagcacagcc cctgctgtgt gggtctgcag gtgagcagac
     1681 aggacaggtg tgccgccacc caagtgccaa gacacagcag ggccaacaac ctgtgcccag
     1741 gccagcttcg agctacatgc atctagggcg gagaggctgc acttgtgaga gaaaatacta
     1801 tttcaagtca tattctgcgt aggaaaatga attggttggg gaaagtcgtg tctgtcagac
     1861 tgccctgggt ggagggagac gccgggctag agcctttggg atcgtcctgg attcactggc
     1921 tttgcggagg ctgctcagat ggcctgagcc tcccgaggct tgctgccccg taggaggaga
     1981 ctgtcttccc gtgggcatat ctggggagcc ctgttccccg ctttttcact cccatacctt
     2041 taatggcccc caaaatctgt cactacaatt taaacaccag tcccgaaatt tggatcttct
     2101 ttctttttga atctctcaaa cggcaacatt cctcagaaac caaagcttta tttcaaatct
     2161 cttccttccc tggctggttc catctagtac cagaggcctc ttttcctgaa gaaatccaat
     2221 cctagccctc attttaatta tgtacatctg tttgtagcca caagcctgaa tttctcagtg
     2281 ttggtaagtt tctttaccta ccctcactat atattattct cgttttaaaa cccataaagg
     2341 agtgatttag aacagtcatt aattttcaac tcaatgaaat atgtgaagcc cagcatctct
     2401 gttgctaaca cacagagctc acctgtttga aaccaagctt tcaaacatgt tgaagctctt
     2461 tactgtaaag gcaagccagc atgtgtgtcc acacatacat aggatggctg gctctgcacc
     2521 tgtaggatat tggaatgcac agggcaattg agggactgag ccagaccttc ggagagtaat
     2581 gccaccagat cccctaggaa agaggaggca aatggcactg caggtgagaa ccccgcccat
     2641 ccgtgctatg acatggaggc actgaagccc gaggaaggtg tgtggagatt ctaatcccaa
     2701 caagcaaggg tctccttcaa gattaatgct atcaatcatt aaggtcatta ctctcaacca
     2761 cctaggcaat gaagaatata ccatttcaaa tatttacagt acttgtcttc accaacactg
     2821 tcccaaggtg aaatgaagca acagagagga aattgtacat aagtacctca gcatttaatc
     2881 caaacagggg ttcttagtct cagcactatg acattttggg ctgactactt atttgttagg
     2941 cgggagctct cctgtgcatt gtaggataat tagcagtatc cctggtggct acccaataga
     3001 cgccagtagc accccgaatt gacaacccaa actctccaga catcaccaac tgtcccctgc
     3061 gaggagaaat cactcctggg ggagaaccac tgacccaaat gaattctaaa ccaatcaaat
     3121 gtctgggaag ccctccaaga aaaaaaatag aaaagcactt gaagaatatt cccaatattc
     3181 ccggtcagca gtatcaaggc tgacttgtgt tcatgtggag tcattataaa ttctataaat
     3241 caattattcc ccttcggtct taaaaatata tttcctcata aacatttgag ttttgttgaa
     3301 aagatggagt ttacaaagat accattcttg agtcatggat ttctctgctc acagaagggt
     3361 gtggcatttg gaaacgggaa taaacaaaat tgctgcacca atgcactgag tgaaggaaga
     3421 gagacagagg atcaagggct ttagacagca ctccttcaat atgcaatcac agagaaagat
     3481 gcgccttatc caagttaata tctctaaggt gagagccttc ttagagtcag tttgttgcaa
     3541 atttcaccta ctctgttctt ttccatccat ccccctgagt cagttggttg aagggagtta
     3601 ttttttcaag tggaattcaa acaaagctca aaccagaact gtaaatagtg attgcaggaa
     3661 ttcttttcta aactgctttg ccctttcctc tcactgcctt ttatagccaa tataaatgtc
     3721 tctttgcaca ccttttgttg tggttttata ttgtaacacc atttttcttt gaaactattg
     3781 tatttaaagt aaggtttcat attatgtcag caagtaatta acttatgttt aaaaggtggc
     3841 catatcatgt accaaaagtt gctgaagttt ctcttctagc tggtaaagta ggagtttgca
     3901 tgacttcaca ctttttttgc gtagtttctt ctgttgtatg atggcgtgag tgtgtgtctt
     3961 gggtaccgct gtgtactact gtgtgcctag attccatgca ctctcgttgt gtttgaagta
     4021 aatattggag accggagggt aacaggttgg cctgttgatt acagctagta atcgctgtgt
     4081 cttgttccgc cccctccctg acaccccagc ttcccaggat gtggaaagcc tggatctcag
     4141 ctccttgccc catatccctt ctgtaatttg tacctaaaga gtgtgattat cctaattcaa
     4201 gagtcactaa aactcatcac attatcattg catatcagca aagggtaaag tcctagcacc
     4261 aattgcttca cataccagca tgttccattt ccaatttaga attagccaca taataaaatc
     4321 ttagaatctt ccttgagaaa gagctgcctg agatgtagtt ttgttatatg gttccccacc
     4381 gaccattttt gtgctttttt cttgttttgt tttgttttga ctgcactgtg agttttgtag
     4441 tgtcctcttc ttgccaaaac aaacgcgaga tgaactggac ttatgtagac aaatcgtgat
     4501 gccagtgtat ccttcctttc ttcagttcca gcaataatga atggtcaact tttttaaaat
     4561 ctagatctct ctcattcatt tcaatgtatt tttactttaa gatgaaccaa aattattaga
     4621 cttatttaag atgtacaggc atcagaaaaa agaagcacat aatgcttttg gtgcgatggc
     4681 actcactgtg aacatgtgta accacatatt aatatgcaat attgtttcca atactttcta
     4741 atacagtttt ttataatgtt gtgtgtggtg attgttcagg tcgaatctgt tgtatccagt
     4801 acagctttag gtcttcagct gcccttctgg cgagtacatg cacaggattg taaatgagaa
     4861 atgcagtcat atttccagtc tgcctctatg atgatgttaa attattgctg tttagctgtg
     4921 aacaagggat gtaccactgg aggaatagag tatccttttg tacacatttt gaaatgcttc
     4981 ttctgtagtg atagaacaaa taaatgcaac gaatactctg tctgccctat cccgtgaagt
     5041 ccacactggc gtaagagaag gcccagcaga gcaggaatct gcctagactt tctcccaatg
     5101 agatcccaat atgagaggga gaagagatgg gcctcaggac agctgcaata ccacttggga
     5161 acacatgtgg tgtcttgatg tggccagcgc agcagttcag cacaacgtac ctcccatcta
     5221 caacagtgct ggacgtggga attctaagtc ccagtcttga gggtgggtgg agatggaggg
     5281 caacaagaga tacatttcca gttctccact gcagcatgct tcagtcattc tgtgagtggc
     5341 cgggcccagg gccctcacaa tttcactacc ttgtctttta catagtcata agaattatcc
     5401 tcaacatagc cttttgacgc tgtaaatctt gagtattcat ttaccctttt ctgatctcct
     5461 ggaaacagct gcctgcctgc attgcacttc tcttcccgag gagtggggta aatttaaaag
     5521 tcaagttata gtttggatgt tagtatagaa ttttgaaatt gggaattaaa aatcaggact
     5581 ggggactggg agaccaaaaa tttctgatcc catttctgat ggatgtgtca caccttttct
     5641 gtcaaaataa aatgtcttgg aggttatgac tccttggtga aa
//
