LOCUS       XM_047419740            5898 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens IKAROS family zinc finger 1 (IKZF1),
            transcript variant X29, mRNA.
ACCESSION   XM_047419740
VERSION     XM_047419740.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000007.14) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5898
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
     gene            1..5898
                     /gene="IKZF1"
                     /gene_synonym="CVID13; Hs.54452; IK1; IKAROS; LyF-1; LYF1;
                     PPP1R92; PRO0758; ZNFN1A1"
                     /note="IKAROS family zinc finger 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 10
                     ESTs, 732 long SRA reads, 2 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 24 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:10320"
                     /db_xref="HGNC:HGNC:13176"
                     /db_xref="MIM:603023"
     CDS             66..1424
                     /gene="IKZF1"
                     /gene_synonym="CVID13; Hs.54452; IK1; IKAROS; LyF-1; LYF1;
                     PPP1R92; PRO0758; ZNFN1A1"
                     /codon_start=1
                     /product="DNA-binding protein Ikaros isoform X21"
                     /protein_id="XP_047275696.1"
                     /db_xref="GeneID:10320"
                     /db_xref="HGNC:HGNC:13176"
                     /db_xref="MIM:603023"
                     /translation="MDADEGQDMSQVSGKESPPVSDTPDEGDEPMPIPEDLSTTSGGQ
                     QSSKSDRVVVTYGADDFRDFHAIIPKSFSRERPFQCNQCGASFTQKGNLLRHIKLHSG
                     EKPFKCHLCNYACRRRDALTGHLRTHSVGKPHKCGYCGRSYKQRSSLEEHKERCHNYL
                     ESMGLPGTLYPVIKEETNHSEMAEDLCKIGSERSLVLDRLASNVAKRKSSMPQKFLGD
                     KGLSDTPYDSSASYEKENEMMKSHVMDQAINNAINYLGAESLRPLVQTPPGGSEVVPV
                     ISPMYQLHKPLAEGTPRSNHSAQDSAVENLLLLSKAKLVPSEREASPSNSCQDSTDTE
                     SNNEEQRSGLIYLTNHIAPHARNGLSLKEEHRAYDLLRAASENSQDALRVVSTSGEQM
                     KVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRFH
                     MS"
ORIGIN      
        1 gagcgggccc ggcgcgggcg agcgggctgc agccggcggc ggcgccagca gataacctga
       61 ggaccatgga tgctgatgag ggtcaagaca tgtcccaagt ttcagggaag gaaagccccc
      121 ctgtaagcga tactccagat gagggcgatg agcccatgcc gatccccgag gacctctcca
      181 ccacctcggg aggacagcaa agctccaaga gtgacagagt cgtggttaca tatggggctg
      241 atgactttag ggatttccat gcaataattc ccaaatcttt ctctcgagaa cggcccttcc
      301 agtgcaatca gtgcggggcc tcattcaccc agaagggcaa cctgctccgg cacatcaagc
      361 tgcattccgg ggagaagccc ttcaaatgcc acctctgcaa ctacgcctgc cgccggaggg
      421 acgccctcac tggccacctg aggacgcact ccgttggtaa acctcacaaa tgtggatatt
      481 gtggccgaag ctataaacag cgaagctctt tagaggaaca taaagagcgc tgccacaact
      541 acttggaaag catgggcctt ccgggcacac tgtacccagt cattaaagaa gaaactaatc
      601 acagtgaaat ggcagaagac ctgtgcaaga taggatcaga gagatctctc gtgctggaca
      661 gactagcaag taacgtcgcc aaacgtaaga gctctatgcc tcagaaattt cttggggaca
      721 agggcctgtc cgacacgccc tacgacagca gcgccagcta cgagaaggag aacgaaatga
      781 tgaagtccca cgtgatggac caagccatca acaacgccat caactacctg ggggccgagt
      841 ccctgcgccc gctggtgcag acgcccccgg gcggttccga ggtggtcccg gtcatcagcc
      901 cgatgtacca gctgcacaag ccgctcgcgg agggcacccc gcgctccaac cactcggccc
      961 aggacagcgc cgtggagaac ctgctgctgc tctccaaggc caagttggtg ccctcggagc
     1021 gcgaggcgtc cccgagcaac agctgccaag actccacgga caccgagagc aacaacgagg
     1081 agcagcgcag cggtctcatc tacctgacca accacatcgc cccgcacgcg cgcaacgggc
     1141 tgtcgctcaa ggaggagcac cgcgcctacg acctgctgcg cgccgcctcc gagaactcgc
     1201 aggacgcgct ccgcgtggtc agcaccagcg gggagcagat gaaggtgtac aagtgcgaac
     1261 actgccgggt gctcttcctg gatcacgtca tgtacaccat ccacatgggc tgccacggct
     1321 tccgtgatcc ttttgagtgc aacatgtgcg gctaccacag ccaggaccgg tacgagttct
     1381 cgtcgcacat aacgcgaggg gagcaccgct tccacatgag ctaaagccct cccgcgcccc
     1441 caccccagac cccgagccac cccaggaaaa gcacaaggac tgccgccttc tcgctcccgc
     1501 cagcagcata gactggactg gaccagacaa tgttgtgttt ggatttgtaa ctgttttttg
     1561 ttttttgttt gagttggttg attggggttt gatttgcttt tgaaaagatt tttattttta
     1621 gaggcagggc tgcattggga gcatccagaa ctgctacctt cctagatgtt tccccagacc
     1681 gctggctgag attccctcac ctgtcgcttc ctagaatccc cttctccaaa cgattagtct
     1741 aaattttcag agagaaatag ataaaacacg ccacagcctg ggaaggagcg tgctctaccc
     1801 tgtgctaagc acggggttcg cgcaccaggt gtctttttcc agtccccaga agcagagagc
     1861 acagcccctg ctgtgtgggt ctgcaggtga gcagacagga caggtgtgcc gccacccaag
     1921 tgccaagaca cagcagggcc aacaacctgt gcccaggcca gcttcgagct acatgcatct
     1981 agggcggaga ggctgcactt gtgagagaaa atactatttc aagtcatatt ctgcgtagga
     2041 aaatgaattg gttggggaaa gtcgtgtctg tcagactgcc ctgggtggag ggagacgccg
     2101 ggctagagcc tttgggatcg tcctggattc actggctttg cggaggctgc tcagatggcc
     2161 tgagcctccc gaggcttgct gccccgtagg aggagactgt cttcccgtgg gcatatctgg
     2221 ggagccctgt tccccgcttt ttcactccca tacctttaat ggcccccaaa atctgtcact
     2281 acaatttaaa caccagtccc gaaatttgga tcttctttct ttttgaatct ctcaaacggc
     2341 aacattcctc agaaaccaaa gctttatttc aaatctcttc cttccctggc tggttccatc
     2401 tagtaccaga ggcctctttt cctgaagaaa tccaatccta gccctcattt taattatgta
     2461 catctgtttg tagccacaag cctgaatttc tcagtgttgg taagtttctt tacctaccct
     2521 cactatatat tattctcgtt ttaaaaccca taaaggagtg atttagaaca gtcattaatt
     2581 ttcaactcaa tgaaatatgt gaagcccagc atctctgttg ctaacacaca gagctcacct
     2641 gtttgaaacc aagctttcaa acatgttgaa gctctttact gtaaaggcaa gccagcatgt
     2701 gtgtccacac atacatagga tggctggctc tgcacctgta ggatattgga atgcacaggg
     2761 caattgaggg actgagccag accttcggag agtaatgcca ccagatcccc taggaaagag
     2821 gaggcaaatg gcactgcagg tgagaacccc gcccatccgt gctatgacat ggaggcactg
     2881 aagcccgagg aaggtgtgtg gagattctaa tcccaacaag caagggtctc cttcaagatt
     2941 aatgctatca atcattaagg tcattactct caaccaccta ggcaatgaag aatataccat
     3001 ttcaaatatt tacagtactt gtcttcacca acactgtccc aaggtgaaat gaagcaacag
     3061 agaggaaatt gtacataagt acctcagcat ttaatccaaa caggggttct tagtctcagc
     3121 actatgacat tttgggctga ctacttattt gttaggcggg agctctcctg tgcattgtag
     3181 gataattagc agtatccctg gtggctaccc aatagacgcc agtagcaccc cgaattgaca
     3241 acccaaactc tccagacatc accaactgtc ccctgcgagg agaaatcact cctgggggag
     3301 aaccactgac ccaaatgaat tctaaaccaa tcaaatgtct gggaagccct ccaagaaaaa
     3361 aaatagaaaa gcacttgaag aatattccca atattcccgg tcagcagtat caaggctgac
     3421 ttgtgttcat gtggagtcat tataaattct ataaatcaat tattcccctt cggtcttaaa
     3481 aatatatttc ctcataaaca tttgagtttt gttgaaaaga tggagtttac aaagatacca
     3541 ttcttgagtc atggatttct ctgctcacag aagggtgtgg catttggaaa cgggaataaa
     3601 caaaattgct gcaccaatgc actgagtgaa ggaagagaga cagaggatca agggctttag
     3661 acagcactcc ttcaatatgc aatcacagag aaagatgcgc cttatccaag ttaatatctc
     3721 taaggtgaga gccttcttag agtcagtttg ttgcaaattt cacctactct gttcttttcc
     3781 atccatcccc ctgagtcagt tggttgaagg gagttatttt ttcaagtgga attcaaacaa
     3841 agctcaaacc agaactgtaa atagtgattg caggaattct tttctaaact gctttgccct
     3901 ttcctctcac tgccttttat agccaatata aatgtctctt tgcacacctt ttgttgtggt
     3961 tttatattgt aacaccattt ttctttgaaa ctattgtatt taaagtaagg tttcatatta
     4021 tgtcagcaag taattaactt atgtttaaaa ggtggccata tcatgtacca aaagttgctg
     4081 aagtttctct tctagctggt aaagtaggag tttgcatgac ttcacacttt ttttgcgtag
     4141 tttcttctgt tgtatgatgg cgtgagtgtg tgtcttgggt accgctgtgt actactgtgt
     4201 gcctagattc catgcactct cgttgtgttt gaagtaaata ttggagaccg gagggtaaca
     4261 ggttggcctg ttgattacag ctagtaatcg ctgtgtcttg ttccgccccc tccctgacac
     4321 cccagcttcc caggatgtgg aaagcctgga tctcagctcc ttgccccata tcccttctgt
     4381 aatttgtacc taaagagtgt gattatccta attcaagagt cactaaaact catcacatta
     4441 tcattgcata tcagcaaagg gtaaagtcct agcaccaatt gcttcacata ccagcatgtt
     4501 ccatttccaa tttagaatta gccacataat aaaatcttag aatcttcctt gagaaagagc
     4561 tgcctgagat gtagttttgt tatatggttc cccaccgacc atttttgtgc ttttttcttg
     4621 ttttgttttg ttttgactgc actgtgagtt ttgtagtgtc ctcttcttgc caaaacaaac
     4681 gcgagatgaa ctggacttat gtagacaaat cgtgatgcca gtgtatcctt cctttcttca
     4741 gttccagcaa taatgaatgg tcaacttttt taaaatctag atctctctca ttcatttcaa
     4801 tgtattttta ctttaagatg aaccaaaatt attagactta tttaagatgt acaggcatca
     4861 gaaaaaagaa gcacataatg cttttggtgc gatggcactc actgtgaaca tgtgtaacca
     4921 catattaata tgcaatattg tttccaatac tttctaatac agttttttat aatgttgtgt
     4981 gtggtgattg ttcaggtcga atctgttgta tccagtacag ctttaggtct tcagctgccc
     5041 ttctggcgag tacatgcaca ggattgtaaa tgagaaatgc agtcatattt ccagtctgcc
     5101 tctatgatga tgttaaatta ttgctgttta gctgtgaaca agggatgtac cactggagga
     5161 atagagtatc cttttgtaca cattttgaaa tgcttcttct gtagtgatag aacaaataaa
     5221 tgcaacgaat actctgtctg ccctatcccg tgaagtccac actggcgtaa gagaaggccc
     5281 agcagagcag gaatctgcct agactttctc ccaatgagat cccaatatga gagggagaag
     5341 agatgggcct caggacagct gcaataccac ttgggaacac atgtggtgtc ttgatgtggc
     5401 cagcgcagca gttcagcaca acgtacctcc catctacaac agtgctggac gtgggaattc
     5461 taagtcccag tcttgagggt gggtggagat ggagggcaac aagagataca tttccagttc
     5521 tccactgcag catgcttcag tcattctgtg agtggccggg cccagggccc tcacaatttc
     5581 actaccttgt cttttacata gtcataagaa ttatcctcaa catagccttt tgacgctgta
     5641 aatcttgagt attcatttac ccttttctga tctcctggaa acagctgcct gcctgcattg
     5701 cacttctctt cccgaggagt ggggtaaatt taaaagtcaa gttatagttt ggatgttagt
     5761 atagaatttt gaaattggga attaaaaatc aggactgggg actgggagac caaaaatttc
     5821 tgatcccatt tctgatggat gtgtcacacc ttttctgtca aaataaaatg tcttggaggt
     5881 tatgactcct tggtgaaa
//
