LOCUS       XM_047419728            6069 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens IKAROS family zinc finger 1 (IKZF1),
            transcript variant X15, mRNA.
ACCESSION   XM_047419728
VERSION     XM_047419728.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000007.14) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6069
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
     gene            1..6069
                     /gene="IKZF1"
                     /gene_synonym="CVID13; Hs.54452; IK1; IKAROS; LyF-1; LYF1;
                     PPP1R92; PRO0758; ZNFN1A1"
                     /note="IKAROS family zinc finger 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 14
                     ESTs, 701 long SRA reads, 4 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 30 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:10320"
                     /db_xref="HGNC:HGNC:13176"
                     /db_xref="MIM:603023"
     CDS             66..1595
                     /gene="IKZF1"
                     /gene_synonym="CVID13; Hs.54452; IK1; IKAROS; LyF-1; LYF1;
                     PPP1R92; PRO0758; ZNFN1A1"
                     /codon_start=1
                     /product="DNA-binding protein Ikaros isoform X11"
                     /protein_id="XP_047275684.1"
                     /db_xref="GeneID:10320"
                     /db_xref="HGNC:HGNC:13176"
                     /db_xref="MIM:603023"
                     /translation="MDADEGQDMSQVSGKESPPVSDTPDEGDEPMPIPEDLSTTSGGQ
                     QSSKSDRVVASNVKVETQSDEENGRACEMNGEECAEDLRMLDASGEKMNGSHRDQGSS
                     ALSGVGGIRLPNGKLKCDICGIICIGPNVLMVHKRSHTGERPFQCNQCGASFTQKGNL
                     LRHIKLHSGEKPFKCHLCNYACRRRDALTGHLRTHSVGKPHKCGYCGRSYKQRSSLEE
                     HKERCHNYLESMGLPGTLYPVIKEETNHSEMAEDLCKIGSERSLVLDRLASNVAKRDK
                     GLSDTPYDSSASYEKENEMMKSHVMDQAINNAINYLGAESLRPLVQTPPGGSEVVPVI
                     SPMYQLHKPLAEGTPRSNHSAQDSAVENLLLLSKAKLVPSEREASPSNSCQDSTDTES
                     NNEEQRSGLIYLTNHIAPHARNGLSLKEEHRAYDLLRAASENSQDALRVVSTSGEQMK
                     VYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRFHM
                     S"
ORIGIN      
        1 gagcgggccc ggcgcgggcg agcgggctgc agccggcggc ggcgccagca gataacctga
       61 ggaccatgga tgctgatgag ggtcaagaca tgtcccaagt ttcagggaag gaaagccccc
      121 ctgtaagcga tactccagat gagggcgatg agcccatgcc gatccccgag gacctctcca
      181 ccacctcggg aggacagcaa agctccaaga gtgacagagt cgtggccagt aatgttaaag
      241 tagagactca gagtgatgaa gagaatgggc gtgcctgtga aatgaatggg gaagaatgtg
      301 cggaggattt acgaatgctt gatgcctcgg gagagaaaat gaatggctcc cacagggacc
      361 aaggcagctc ggctttgtcg ggagttggag gcattcgact tcctaacgga aaactaaagt
      421 gtgatatctg tgggatcatt tgcatcgggc ccaatgtgct catggttcac aaaagaagcc
      481 acactggaga acggcccttc cagtgcaatc agtgcggggc ctcattcacc cagaagggca
      541 acctgctccg gcacatcaag ctgcattccg gggagaagcc cttcaaatgc cacctctgca
      601 actacgcctg ccgccggagg gacgccctca ctggccacct gaggacgcac tccgttggta
      661 aacctcacaa atgtggatat tgtggccgaa gctataaaca gcgaagctct ttagaggaac
      721 ataaagagcg ctgccacaac tacttggaaa gcatgggcct tccgggcaca ctgtacccag
      781 tcattaaaga agaaactaat cacagtgaaa tggcagaaga cctgtgcaag ataggatcag
      841 agagatctct cgtgctggac agactagcaa gtaacgtcgc caaacgggac aagggcctgt
      901 ccgacacgcc ctacgacagc agcgccagct acgagaagga gaacgaaatg atgaagtccc
      961 acgtgatgga ccaagccatc aacaacgcca tcaactacct gggggccgag tccctgcgcc
     1021 cgctggtgca gacgcccccg ggcggttccg aggtggtccc ggtcatcagc ccgatgtacc
     1081 agctgcacaa gccgctcgcg gagggcaccc cgcgctccaa ccactcggcc caggacagcg
     1141 ccgtggagaa cctgctgctg ctctccaagg ccaagttggt gccctcggag cgcgaggcgt
     1201 ccccgagcaa cagctgccaa gactccacgg acaccgagag caacaacgag gagcagcgca
     1261 gcggtctcat ctacctgacc aaccacatcg ccccgcacgc gcgcaacggg ctgtcgctca
     1321 aggaggagca ccgcgcctac gacctgctgc gcgccgcctc cgagaactcg caggacgcgc
     1381 tccgcgtggt cagcaccagc ggggagcaga tgaaggtgta caagtgcgaa cactgccggg
     1441 tgctcttcct ggatcacgtc atgtacacca tccacatggg ctgccacggc ttccgtgatc
     1501 cttttgagtg caacatgtgc ggctaccaca gccaggaccg gtacgagttc tcgtcgcaca
     1561 taacgcgagg ggagcaccgc ttccacatga gctaaagccc tcccgcgccc ccaccccaga
     1621 ccccgagcca ccccaggaaa agcacaagga ctgccgcctt ctcgctcccg ccagcagcat
     1681 agactggact ggaccagaca atgttgtgtt tggatttgta actgtttttt gttttttgtt
     1741 tgagttggtt gattggggtt tgatttgctt ttgaaaagat ttttattttt agaggcaggg
     1801 ctgcattggg agcatccaga actgctacct tcctagatgt ttccccagac cgctggctga
     1861 gattccctca cctgtcgctt cctagaatcc ccttctccaa acgattagtc taaattttca
     1921 gagagaaata gataaaacac gccacagcct gggaaggagc gtgctctacc ctgtgctaag
     1981 cacggggttc gcgcaccagg tgtctttttc cagtccccag aagcagagag cacagcccct
     2041 gctgtgtggg tctgcaggtg agcagacagg acaggtgtgc cgccacccaa gtgccaagac
     2101 acagcagggc caacaacctg tgcccaggcc agcttcgagc tacatgcatc tagggcggag
     2161 aggctgcact tgtgagagaa aatactattt caagtcatat tctgcgtagg aaaatgaatt
     2221 ggttggggaa agtcgtgtct gtcagactgc cctgggtgga gggagacgcc gggctagagc
     2281 ctttgggatc gtcctggatt cactggcttt gcggaggctg ctcagatggc ctgagcctcc
     2341 cgaggcttgc tgccccgtag gaggagactg tcttcccgtg ggcatatctg gggagccctg
     2401 ttccccgctt tttcactccc atacctttaa tggcccccaa aatctgtcac tacaatttaa
     2461 acaccagtcc cgaaatttgg atcttctttc tttttgaatc tctcaaacgg caacattcct
     2521 cagaaaccaa agctttattt caaatctctt ccttccctgg ctggttccat ctagtaccag
     2581 aggcctcttt tcctgaagaa atccaatcct agccctcatt ttaattatgt acatctgttt
     2641 gtagccacaa gcctgaattt ctcagtgttg gtaagtttct ttacctaccc tcactatata
     2701 ttattctcgt tttaaaaccc ataaaggagt gatttagaac agtcattaat tttcaactca
     2761 atgaaatatg tgaagcccag catctctgtt gctaacacac agagctcacc tgtttgaaac
     2821 caagctttca aacatgttga agctctttac tgtaaaggca agccagcatg tgtgtccaca
     2881 catacatagg atggctggct ctgcacctgt aggatattgg aatgcacagg gcaattgagg
     2941 gactgagcca gaccttcgga gagtaatgcc accagatccc ctaggaaaga ggaggcaaat
     3001 ggcactgcag gtgagaaccc cgcccatccg tgctatgaca tggaggcact gaagcccgag
     3061 gaaggtgtgt ggagattcta atcccaacaa gcaagggtct ccttcaagat taatgctatc
     3121 aatcattaag gtcattactc tcaaccacct aggcaatgaa gaatatacca tttcaaatat
     3181 ttacagtact tgtcttcacc aacactgtcc caaggtgaaa tgaagcaaca gagaggaaat
     3241 tgtacataag tacctcagca tttaatccaa acaggggttc ttagtctcag cactatgaca
     3301 ttttgggctg actacttatt tgttaggcgg gagctctcct gtgcattgta ggataattag
     3361 cagtatccct ggtggctacc caatagacgc cagtagcacc ccgaattgac aacccaaact
     3421 ctccagacat caccaactgt cccctgcgag gagaaatcac tcctggggga gaaccactga
     3481 cccaaatgaa ttctaaacca atcaaatgtc tgggaagccc tccaagaaaa aaaatagaaa
     3541 agcacttgaa gaatattccc aatattcccg gtcagcagta tcaaggctga cttgtgttca
     3601 tgtggagtca ttataaattc tataaatcaa ttattcccct tcggtcttaa aaatatattt
     3661 cctcataaac atttgagttt tgttgaaaag atggagttta caaagatacc attcttgagt
     3721 catggatttc tctgctcaca gaagggtgtg gcatttggaa acgggaataa acaaaattgc
     3781 tgcaccaatg cactgagtga aggaagagag acagaggatc aagggcttta gacagcactc
     3841 cttcaatatg caatcacaga gaaagatgcg ccttatccaa gttaatatct ctaaggtgag
     3901 agccttctta gagtcagttt gttgcaaatt tcacctactc tgttcttttc catccatccc
     3961 cctgagtcag ttggttgaag ggagttattt tttcaagtgg aattcaaaca aagctcaaac
     4021 cagaactgta aatagtgatt gcaggaattc ttttctaaac tgctttgccc tttcctctca
     4081 ctgcctttta tagccaatat aaatgtctct ttgcacacct tttgttgtgg ttttatattg
     4141 taacaccatt tttctttgaa actattgtat ttaaagtaag gtttcatatt atgtcagcaa
     4201 gtaattaact tatgtttaaa aggtggccat atcatgtacc aaaagttgct gaagtttctc
     4261 ttctagctgg taaagtagga gtttgcatga cttcacactt tttttgcgta gtttcttctg
     4321 ttgtatgatg gcgtgagtgt gtgtcttggg taccgctgtg tactactgtg tgcctagatt
     4381 ccatgcactc tcgttgtgtt tgaagtaaat attggagacc ggagggtaac aggttggcct
     4441 gttgattaca gctagtaatc gctgtgtctt gttccgcccc ctccctgaca ccccagcttc
     4501 ccaggatgtg gaaagcctgg atctcagctc cttgccccat atcccttctg taatttgtac
     4561 ctaaagagtg tgattatcct aattcaagag tcactaaaac tcatcacatt atcattgcat
     4621 atcagcaaag ggtaaagtcc tagcaccaat tgcttcacat accagcatgt tccatttcca
     4681 atttagaatt agccacataa taaaatctta gaatcttcct tgagaaagag ctgcctgaga
     4741 tgtagttttg ttatatggtt ccccaccgac catttttgtg cttttttctt gttttgtttt
     4801 gttttgactg cactgtgagt tttgtagtgt cctcttcttg ccaaaacaaa cgcgagatga
     4861 actggactta tgtagacaaa tcgtgatgcc agtgtatcct tcctttcttc agttccagca
     4921 ataatgaatg gtcaactttt ttaaaatcta gatctctctc attcatttca atgtattttt
     4981 actttaagat gaaccaaaat tattagactt atttaagatg tacaggcatc agaaaaaaga
     5041 agcacataat gcttttggtg cgatggcact cactgtgaac atgtgtaacc acatattaat
     5101 atgcaatatt gtttccaata ctttctaata cagtttttta taatgttgtg tgtggtgatt
     5161 gttcaggtcg aatctgttgt atccagtaca gctttaggtc ttcagctgcc cttctggcga
     5221 gtacatgcac aggattgtaa atgagaaatg cagtcatatt tccagtctgc ctctatgatg
     5281 atgttaaatt attgctgttt agctgtgaac aagggatgta ccactggagg aatagagtat
     5341 ccttttgtac acattttgaa atgcttcttc tgtagtgata gaacaaataa atgcaacgaa
     5401 tactctgtct gccctatccc gtgaagtcca cactggcgta agagaaggcc cagcagagca
     5461 ggaatctgcc tagactttct cccaatgaga tcccaatatg agagggagaa gagatgggcc
     5521 tcaggacagc tgcaatacca cttgggaaca catgtggtgt cttgatgtgg ccagcgcagc
     5581 agttcagcac aacgtacctc ccatctacaa cagtgctgga cgtgggaatt ctaagtccca
     5641 gtcttgaggg tgggtggaga tggagggcaa caagagatac atttccagtt ctccactgca
     5701 gcatgcttca gtcattctgt gagtggccgg gcccagggcc ctcacaattt cactaccttg
     5761 tcttttacat agtcataaga attatcctca acatagcctt ttgacgctgt aaatcttgag
     5821 tattcattta cccttttctg atctcctgga aacagctgcc tgcctgcatt gcacttctct
     5881 tcccgaggag tggggtaaat ttaaaagtca agttatagtt tggatgttag tatagaattt
     5941 tgaaattggg aattaaaaat caggactggg gactgggaga ccaaaaattt ctgatcccat
     6001 ttctgatgga tgtgtcacac cttttctgtc aaaataaaat gtcttggagg ttatgactcc
     6061 ttggtgaaa
//
