LOCUS       XM_011515071            5933 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens IKAROS family zinc finger 1 (IKZF1),
            transcript variant X23, mRNA.
ACCESSION   XM_011515071
VERSION     XM_011515071.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000007.14) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011515071.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5933
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
     gene            1..5933
                     /gene="IKZF1"
                     /gene_synonym="CVID13; Hs.54452; IK1; IKAROS; LyF-1; LYF1;
                     PPP1R92; PRO0758; ZNFN1A1"
                     /note="IKAROS family zinc finger 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 10 ESTs, 716 long SRA reads, 2 Proteins, and 99%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 11 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:10320"
                     /db_xref="HGNC:HGNC:13176"
                     /db_xref="MIM:603023"
     CDS             29..1459
                     /gene="IKZF1"
                     /gene_synonym="CVID13; Hs.54452; IK1; IKAROS; LyF-1; LYF1;
                     PPP1R92; PRO0758; ZNFN1A1"
                     /codon_start=1
                     /product="DNA-binding protein Ikaros isoform X17"
                     /protein_id="XP_011513373.1"
                     /db_xref="GeneID:10320"
                     /db_xref="HGNC:HGNC:13176"
                     /db_xref="MIM:603023"
                     /translation="MEGAILTSAVSRWEGRETRDNLRTMDADEGQDMSQVSGKESPPV
                     SDTPDEGDEPMPIPEDLSTTSGGQQSSKSDRVVVTYGADDFRDFHAIIPKSFSRERPF
                     QCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYACRRRDALTGHLRTHSVGKPHKC
                     GYCGRSYKQRSSLEEHKERCHNYLESMGLPGTLYPVIKEETNHSEMAEDLCKIGSERS
                     LVLDRLASNVAKRKSSMPQKFLGDKGLSDTPYDSSASYEKENEMMKSHVMDQAINNAI
                     NYLGAESLRPLVQTPPGGSEVVPVISPMYQLHKPLAEGTPRSNHSAQDSAVENLLLLS
                     KAKLVPSEREASPSNSCQDSTDTESNNEEQRSGLIYLTNHIAPHARNGLSLKEEHRAY
                     DLLRAASENSQDALRVVSTSGEQMKVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECN
                     MCGYHSQDRYEFSSHITRGEHRFHMS"
ORIGIN      
        1 acgcacttgt gtgtgcaccc aggccaacat ggaaggcgcc atcctaactt ctgccgtgag
       61 caggtgggag ggaagagaga cgagagataa cctgaggacc atggatgctg atgagggtca
      121 agacatgtcc caagtttcag ggaaggaaag cccccctgta agcgatactc cagatgaggg
      181 cgatgagccc atgccgatcc ccgaggacct ctccaccacc tcgggaggac agcaaagctc
      241 caagagtgac agagtcgtgg ttacatatgg ggctgatgac tttagggatt tccatgcaat
      301 aattcccaaa tctttctctc gagaacggcc cttccagtgc aatcagtgcg gggcctcatt
      361 cacccagaag ggcaacctgc tccggcacat caagctgcat tccggggaga agcccttcaa
      421 atgccacctc tgcaactacg cctgccgccg gagggacgcc ctcactggcc acctgaggac
      481 gcactccgtt ggtaaacctc acaaatgtgg atattgtggc cgaagctata aacagcgaag
      541 ctctttagag gaacataaag agcgctgcca caactacttg gaaagcatgg gccttccggg
      601 cacactgtac ccagtcatta aagaagaaac taatcacagt gaaatggcag aagacctgtg
      661 caagatagga tcagagagat ctctcgtgct ggacagacta gcaagtaacg tcgccaaacg
      721 taagagctct atgcctcaga aatttcttgg ggacaagggc ctgtccgaca cgccctacga
      781 cagcagcgcc agctacgaga aggagaacga aatgatgaag tcccacgtga tggaccaagc
      841 catcaacaac gccatcaact acctgggggc cgagtccctg cgcccgctgg tgcagacgcc
      901 cccgggcggt tccgaggtgg tcccggtcat cagcccgatg taccagctgc acaagccgct
      961 cgcggagggc accccgcgct ccaaccactc ggcccaggac agcgccgtgg agaacctgct
     1021 gctgctctcc aaggccaagt tggtgccctc ggagcgcgag gcgtccccga gcaacagctg
     1081 ccaagactcc acggacaccg agagcaacaa cgaggagcag cgcagcggtc tcatctacct
     1141 gaccaaccac atcgccccgc acgcgcgcaa cgggctgtcg ctcaaggagg agcaccgcgc
     1201 ctacgacctg ctgcgcgccg cctccgagaa ctcgcaggac gcgctccgcg tggtcagcac
     1261 cagcggggag cagatgaagg tgtacaagtg cgaacactgc cgggtgctct tcctggatca
     1321 cgtcatgtac accatccaca tgggctgcca cggcttccgt gatccttttg agtgcaacat
     1381 gtgcggctac cacagccagg accggtacga gttctcgtcg cacataacgc gaggggagca
     1441 ccgcttccac atgagctaaa gccctcccgc gcccccaccc cagaccccga gccaccccag
     1501 gaaaagcaca aggactgccg ccttctcgct cccgccagca gcatagactg gactggacca
     1561 gacaatgttg tgtttggatt tgtaactgtt ttttgttttt tgtttgagtt ggttgattgg
     1621 ggtttgattt gcttttgaaa agatttttat ttttagaggc agggctgcat tgggagcatc
     1681 cagaactgct accttcctag atgtttcccc agaccgctgg ctgagattcc ctcacctgtc
     1741 gcttcctaga atccccttct ccaaacgatt agtctaaatt ttcagagaga aatagataaa
     1801 acacgccaca gcctgggaag gagcgtgctc taccctgtgc taagcacggg gttcgcgcac
     1861 caggtgtctt tttccagtcc ccagaagcag agagcacagc ccctgctgtg tgggtctgca
     1921 ggtgagcaga caggacaggt gtgccgccac ccaagtgcca agacacagca gggccaacaa
     1981 cctgtgccca ggccagcttc gagctacatg catctagggc ggagaggctg cacttgtgag
     2041 agaaaatact atttcaagtc atattctgcg taggaaaatg aattggttgg ggaaagtcgt
     2101 gtctgtcaga ctgccctggg tggagggaga cgccgggcta gagcctttgg gatcgtcctg
     2161 gattcactgg ctttgcggag gctgctcaga tggcctgagc ctcccgaggc ttgctgcccc
     2221 gtaggaggag actgtcttcc cgtgggcata tctggggagc cctgttcccc gctttttcac
     2281 tcccatacct ttaatggccc ccaaaatctg tcactacaat ttaaacacca gtcccgaaat
     2341 ttggatcttc tttctttttg aatctctcaa acggcaacat tcctcagaaa ccaaagcttt
     2401 atttcaaatc tcttccttcc ctggctggtt ccatctagta ccagaggcct cttttcctga
     2461 agaaatccaa tcctagccct cattttaatt atgtacatct gtttgtagcc acaagcctga
     2521 atttctcagt gttggtaagt ttctttacct accctcacta tatattattc tcgttttaaa
     2581 acccataaag gagtgattta gaacagtcat taattttcaa ctcaatgaaa tatgtgaagc
     2641 ccagcatctc tgttgctaac acacagagct cacctgtttg aaaccaagct ttcaaacatg
     2701 ttgaagctct ttactgtaaa ggcaagccag catgtgtgtc cacacataca taggatggct
     2761 ggctctgcac ctgtaggata ttggaatgca cagggcaatt gagggactga gccagacctt
     2821 cggagagtaa tgccaccaga tcccctagga aagaggaggc aaatggcact gcaggtgaga
     2881 accccgccca tccgtgctat gacatggagg cactgaagcc cgaggaaggt gtgtggagat
     2941 tctaatccca acaagcaagg gtctccttca agattaatgc tatcaatcat taaggtcatt
     3001 actctcaacc acctaggcaa tgaagaatat accatttcaa atatttacag tacttgtctt
     3061 caccaacact gtcccaaggt gaaatgaagc aacagagagg aaattgtaca taagtacctc
     3121 agcatttaat ccaaacaggg gttcttagtc tcagcactat gacattttgg gctgactact
     3181 tatttgttag gcgggagctc tcctgtgcat tgtaggataa ttagcagtat ccctggtggc
     3241 tacccaatag acgccagtag caccccgaat tgacaaccca aactctccag acatcaccaa
     3301 ctgtcccctg cgaggagaaa tcactcctgg gggagaacca ctgacccaaa tgaattctaa
     3361 accaatcaaa tgtctgggaa gccctccaag aaaaaaaata gaaaagcact tgaagaatat
     3421 tcccaatatt cccggtcagc agtatcaagg ctgacttgtg ttcatgtgga gtcattataa
     3481 attctataaa tcaattattc cccttcggtc ttaaaaatat atttcctcat aaacatttga
     3541 gttttgttga aaagatggag tttacaaaga taccattctt gagtcatgga tttctctgct
     3601 cacagaaggg tgtggcattt ggaaacggga ataaacaaaa ttgctgcacc aatgcactga
     3661 gtgaaggaag agagacagag gatcaagggc tttagacagc actccttcaa tatgcaatca
     3721 cagagaaaga tgcgccttat ccaagttaat atctctaagg tgagagcctt cttagagtca
     3781 gtttgttgca aatttcacct actctgttct tttccatcca tccccctgag tcagttggtt
     3841 gaagggagtt attttttcaa gtggaattca aacaaagctc aaaccagaac tgtaaatagt
     3901 gattgcagga attcttttct aaactgcttt gccctttcct ctcactgcct tttatagcca
     3961 atataaatgt ctctttgcac accttttgtt gtggttttat attgtaacac catttttctt
     4021 tgaaactatt gtatttaaag taaggtttca tattatgtca gcaagtaatt aacttatgtt
     4081 taaaaggtgg ccatatcatg taccaaaagt tgctgaagtt tctcttctag ctggtaaagt
     4141 aggagtttgc atgacttcac actttttttg cgtagtttct tctgttgtat gatggcgtga
     4201 gtgtgtgtct tgggtaccgc tgtgtactac tgtgtgccta gattccatgc actctcgttg
     4261 tgtttgaagt aaatattgga gaccggaggg taacaggttg gcctgttgat tacagctagt
     4321 aatcgctgtg tcttgttccg ccccctccct gacaccccag cttcccagga tgtggaaagc
     4381 ctggatctca gctccttgcc ccatatccct tctgtaattt gtacctaaag agtgtgatta
     4441 tcctaattca agagtcacta aaactcatca cattatcatt gcatatcagc aaagggtaaa
     4501 gtcctagcac caattgcttc acataccagc atgttccatt tccaatttag aattagccac
     4561 ataataaaat cttagaatct tccttgagaa agagctgcct gagatgtagt tttgttatat
     4621 ggttccccac cgaccatttt tgtgcttttt tcttgttttg ttttgttttg actgcactgt
     4681 gagttttgta gtgtcctctt cttgccaaaa caaacgcgag atgaactgga cttatgtaga
     4741 caaatcgtga tgccagtgta tccttccttt cttcagttcc agcaataatg aatggtcaac
     4801 ttttttaaaa tctagatctc tctcattcat ttcaatgtat ttttacttta agatgaacca
     4861 aaattattag acttatttaa gatgtacagg catcagaaaa aagaagcaca taatgctttt
     4921 ggtgcgatgg cactcactgt gaacatgtgt aaccacatat taatatgcaa tattgtttcc
     4981 aatactttct aatacagttt tttataatgt tgtgtgtggt gattgttcag gtcgaatctg
     5041 ttgtatccag tacagcttta ggtcttcagc tgcccttctg gcgagtacat gcacaggatt
     5101 gtaaatgaga aatgcagtca tatttccagt ctgcctctat gatgatgtta aattattgct
     5161 gtttagctgt gaacaaggga tgtaccactg gaggaataga gtatcctttt gtacacattt
     5221 tgaaatgctt cttctgtagt gatagaacaa ataaatgcaa cgaatactct gtctgcccta
     5281 tcccgtgaag tccacactgg cgtaagagaa ggcccagcag agcaggaatc tgcctagact
     5341 ttctcccaat gagatcccaa tatgagaggg agaagagatg ggcctcagga cagctgcaat
     5401 accacttggg aacacatgtg gtgtcttgat gtggccagcg cagcagttca gcacaacgta
     5461 cctcccatct acaacagtgc tggacgtggg aattctaagt cccagtcttg agggtgggtg
     5521 gagatggagg gcaacaagag atacatttcc agttctccac tgcagcatgc ttcagtcatt
     5581 ctgtgagtgg ccgggcccag ggccctcaca atttcactac cttgtctttt acatagtcat
     5641 aagaattatc ctcaacatag ccttttgacg ctgtaaatct tgagtattca tttacccttt
     5701 tctgatctcc tggaaacagc tgcctgcctg cattgcactt ctcttcccga ggagtggggt
     5761 aaatttaaaa gtcaagttat agtttggatg ttagtataga attttgaaat tgggaattaa
     5821 aaatcaggac tggggactgg gagaccaaaa atttctgatc ccatttctga tggatgtgtc
     5881 acaccttttc tgtcaaaata aaatgtcttg gaggttatga ctccttggtg aaa
//
