LOCUS       XM_011515067            6068 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens IKAROS family zinc finger 1 (IKZF1),
            transcript variant X11, mRNA.
ACCESSION   XM_011515067
VERSION     XM_011515067.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000007.14) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011515067.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6068
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
     gene            1..6068
                     /gene="IKZF1"
                     /gene_synonym="CVID13; Hs.54452; IK1; IKAROS; LyF-1; LYF1;
                     PPP1R92; PRO0758; ZNFN1A1"
                     /note="IKAROS family zinc finger 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 11 ESTs, 703 long SRA reads, 6 Proteins, and 99%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 11 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:10320"
                     /db_xref="HGNC:HGNC:13176"
                     /db_xref="MIM:603023"
     CDS             29..1594
                     /gene="IKZF1"
                     /gene_synonym="CVID13; Hs.54452; IK1; IKAROS; LyF-1; LYF1;
                     PPP1R92; PRO0758; ZNFN1A1"
                     /codon_start=1
                     /product="DNA-binding protein Ikaros isoform X8"
                     /protein_id="XP_011513369.1"
                     /db_xref="GeneID:10320"
                     /db_xref="HGNC:HGNC:13176"
                     /db_xref="MIM:603023"
                     /translation="MEGAILTSAVSRWEGRETRDNLRTMDADEGQDMSQVSGKESPPV
                     SDTPDEGDEPMPIPEDLSTTSGGQQSSKSDRVVVTYGADDFRDFHAIIPKSFSPSNVK
                     VETQSDEENGRACEMNGEECAEDLRMLDASGEKMNGSHRDQGSSALSGVGGIRLPNGK
                     LKCDICGIICIGPNVLMVHKRSHTGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFK
                     CHLCNYACRRRDALTGHLRTHSVIKEETNHSEMAEDLCKIGSERSLVLDRLASNVAKR
                     KSSMPQKFLGDKGLSDTPYDSSASYEKENEMMKSHVMDQAINNAINYLGAESLRPLVQ
                     TPPGGSEVVPVISPMYQLHKPLAEGTPRSNHSAQDSAVENLLLLSKAKLVPSEREASP
                     SNSCQDSTDTESNNEEQRSGLIYLTNHIAPHARNGLSLKEEHRAYDLLRAASENSQDA
                     LRVVSTSGEQMKVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFS
                     SHITRGEHRFHMS"
ORIGIN      
        1 acgcacttgt gtgtgcaccc aggccaacat ggaaggcgcc atcctaactt ctgccgtgag
       61 caggtgggag ggaagagaga cgagagataa cctgaggacc atggatgctg atgagggtca
      121 agacatgtcc caagtttcag ggaaggaaag cccccctgta agcgatactc cagatgaggg
      181 cgatgagccc atgccgatcc ccgaggacct ctccaccacc tcgggaggac agcaaagctc
      241 caagagtgac agagtcgtgg ttacatatgg ggctgatgac tttagggatt tccatgcaat
      301 aattcccaaa tctttctctc ccagtaatgt taaagtagag actcagagtg atgaagagaa
      361 tgggcgtgcc tgtgaaatga atggggaaga atgtgcggag gatttacgaa tgcttgatgc
      421 ctcgggagag aaaatgaatg gctcccacag ggaccaaggc agctcggctt tgtcgggagt
      481 tggaggcatt cgacttccta acggaaaact aaagtgtgat atctgtggga tcatttgcat
      541 cgggcccaat gtgctcatgg ttcacaaaag aagccacact ggagaacggc ccttccagtg
      601 caatcagtgc ggggcctcat tcacccagaa gggcaacctg ctccggcaca tcaagctgca
      661 ttccggggag aagcccttca aatgccacct ctgcaactac gcctgccgcc ggagggacgc
      721 cctcactggc cacctgagga cgcactccgt cattaaagaa gaaactaatc acagtgaaat
      781 ggcagaagac ctgtgcaaga taggatcaga gagatctctc gtgctggaca gactagcaag
      841 taacgtcgcc aaacgtaaga gctctatgcc tcagaaattt cttggggaca agggcctgtc
      901 cgacacgccc tacgacagca gcgccagcta cgagaaggag aacgaaatga tgaagtccca
      961 cgtgatggac caagccatca acaacgccat caactacctg ggggccgagt ccctgcgccc
     1021 gctggtgcag acgcccccgg gcggttccga ggtggtcccg gtcatcagcc cgatgtacca
     1081 gctgcacaag ccgctcgcgg agggcacccc gcgctccaac cactcggccc aggacagcgc
     1141 cgtggagaac ctgctgctgc tctccaaggc caagttggtg ccctcggagc gcgaggcgtc
     1201 cccgagcaac agctgccaag actccacgga caccgagagc aacaacgagg agcagcgcag
     1261 cggtctcatc tacctgacca accacatcgc cccgcacgcg cgcaacgggc tgtcgctcaa
     1321 ggaggagcac cgcgcctacg acctgctgcg cgccgcctcc gagaactcgc aggacgcgct
     1381 ccgcgtggtc agcaccagcg gggagcagat gaaggtgtac aagtgcgaac actgccgggt
     1441 gctcttcctg gatcacgtca tgtacaccat ccacatgggc tgccacggct tccgtgatcc
     1501 ttttgagtgc aacatgtgcg gctaccacag ccaggaccgg tacgagttct cgtcgcacat
     1561 aacgcgaggg gagcaccgct tccacatgag ctaaagccct cccgcgcccc caccccagac
     1621 cccgagccac cccaggaaaa gcacaaggac tgccgccttc tcgctcccgc cagcagcata
     1681 gactggactg gaccagacaa tgttgtgttt ggatttgtaa ctgttttttg ttttttgttt
     1741 gagttggttg attggggttt gatttgcttt tgaaaagatt tttattttta gaggcagggc
     1801 tgcattggga gcatccagaa ctgctacctt cctagatgtt tccccagacc gctggctgag
     1861 attccctcac ctgtcgcttc ctagaatccc cttctccaaa cgattagtct aaattttcag
     1921 agagaaatag ataaaacacg ccacagcctg ggaaggagcg tgctctaccc tgtgctaagc
     1981 acggggttcg cgcaccaggt gtctttttcc agtccccaga agcagagagc acagcccctg
     2041 ctgtgtgggt ctgcaggtga gcagacagga caggtgtgcc gccacccaag tgccaagaca
     2101 cagcagggcc aacaacctgt gcccaggcca gcttcgagct acatgcatct agggcggaga
     2161 ggctgcactt gtgagagaaa atactatttc aagtcatatt ctgcgtagga aaatgaattg
     2221 gttggggaaa gtcgtgtctg tcagactgcc ctgggtggag ggagacgccg ggctagagcc
     2281 tttgggatcg tcctggattc actggctttg cggaggctgc tcagatggcc tgagcctccc
     2341 gaggcttgct gccccgtagg aggagactgt cttcccgtgg gcatatctgg ggagccctgt
     2401 tccccgcttt ttcactccca tacctttaat ggcccccaaa atctgtcact acaatttaaa
     2461 caccagtccc gaaatttgga tcttctttct ttttgaatct ctcaaacggc aacattcctc
     2521 agaaaccaaa gctttatttc aaatctcttc cttccctggc tggttccatc tagtaccaga
     2581 ggcctctttt cctgaagaaa tccaatccta gccctcattt taattatgta catctgtttg
     2641 tagccacaag cctgaatttc tcagtgttgg taagtttctt tacctaccct cactatatat
     2701 tattctcgtt ttaaaaccca taaaggagtg atttagaaca gtcattaatt ttcaactcaa
     2761 tgaaatatgt gaagcccagc atctctgttg ctaacacaca gagctcacct gtttgaaacc
     2821 aagctttcaa acatgttgaa gctctttact gtaaaggcaa gccagcatgt gtgtccacac
     2881 atacatagga tggctggctc tgcacctgta ggatattgga atgcacaggg caattgaggg
     2941 actgagccag accttcggag agtaatgcca ccagatcccc taggaaagag gaggcaaatg
     3001 gcactgcagg tgagaacccc gcccatccgt gctatgacat ggaggcactg aagcccgagg
     3061 aaggtgtgtg gagattctaa tcccaacaag caagggtctc cttcaagatt aatgctatca
     3121 atcattaagg tcattactct caaccaccta ggcaatgaag aatataccat ttcaaatatt
     3181 tacagtactt gtcttcacca acactgtccc aaggtgaaat gaagcaacag agaggaaatt
     3241 gtacataagt acctcagcat ttaatccaaa caggggttct tagtctcagc actatgacat
     3301 tttgggctga ctacttattt gttaggcggg agctctcctg tgcattgtag gataattagc
     3361 agtatccctg gtggctaccc aatagacgcc agtagcaccc cgaattgaca acccaaactc
     3421 tccagacatc accaactgtc ccctgcgagg agaaatcact cctgggggag aaccactgac
     3481 ccaaatgaat tctaaaccaa tcaaatgtct gggaagccct ccaagaaaaa aaatagaaaa
     3541 gcacttgaag aatattccca atattcccgg tcagcagtat caaggctgac ttgtgttcat
     3601 gtggagtcat tataaattct ataaatcaat tattcccctt cggtcttaaa aatatatttc
     3661 ctcataaaca tttgagtttt gttgaaaaga tggagtttac aaagatacca ttcttgagtc
     3721 atggatttct ctgctcacag aagggtgtgg catttggaaa cgggaataaa caaaattgct
     3781 gcaccaatgc actgagtgaa ggaagagaga cagaggatca agggctttag acagcactcc
     3841 ttcaatatgc aatcacagag aaagatgcgc cttatccaag ttaatatctc taaggtgaga
     3901 gccttcttag agtcagtttg ttgcaaattt cacctactct gttcttttcc atccatcccc
     3961 ctgagtcagt tggttgaagg gagttatttt ttcaagtgga attcaaacaa agctcaaacc
     4021 agaactgtaa atagtgattg caggaattct tttctaaact gctttgccct ttcctctcac
     4081 tgccttttat agccaatata aatgtctctt tgcacacctt ttgttgtggt tttatattgt
     4141 aacaccattt ttctttgaaa ctattgtatt taaagtaagg tttcatatta tgtcagcaag
     4201 taattaactt atgtttaaaa ggtggccata tcatgtacca aaagttgctg aagtttctct
     4261 tctagctggt aaagtaggag tttgcatgac ttcacacttt ttttgcgtag tttcttctgt
     4321 tgtatgatgg cgtgagtgtg tgtcttgggt accgctgtgt actactgtgt gcctagattc
     4381 catgcactct cgttgtgttt gaagtaaata ttggagaccg gagggtaaca ggttggcctg
     4441 ttgattacag ctagtaatcg ctgtgtcttg ttccgccccc tccctgacac cccagcttcc
     4501 caggatgtgg aaagcctgga tctcagctcc ttgccccata tcccttctgt aatttgtacc
     4561 taaagagtgt gattatccta attcaagagt cactaaaact catcacatta tcattgcata
     4621 tcagcaaagg gtaaagtcct agcaccaatt gcttcacata ccagcatgtt ccatttccaa
     4681 tttagaatta gccacataat aaaatcttag aatcttcctt gagaaagagc tgcctgagat
     4741 gtagttttgt tatatggttc cccaccgacc atttttgtgc ttttttcttg ttttgttttg
     4801 ttttgactgc actgtgagtt ttgtagtgtc ctcttcttgc caaaacaaac gcgagatgaa
     4861 ctggacttat gtagacaaat cgtgatgcca gtgtatcctt cctttcttca gttccagcaa
     4921 taatgaatgg tcaacttttt taaaatctag atctctctca ttcatttcaa tgtattttta
     4981 ctttaagatg aaccaaaatt attagactta tttaagatgt acaggcatca gaaaaaagaa
     5041 gcacataatg cttttggtgc gatggcactc actgtgaaca tgtgtaacca catattaata
     5101 tgcaatattg tttccaatac tttctaatac agttttttat aatgttgtgt gtggtgattg
     5161 ttcaggtcga atctgttgta tccagtacag ctttaggtct tcagctgccc ttctggcgag
     5221 tacatgcaca ggattgtaaa tgagaaatgc agtcatattt ccagtctgcc tctatgatga
     5281 tgttaaatta ttgctgttta gctgtgaaca agggatgtac cactggagga atagagtatc
     5341 cttttgtaca cattttgaaa tgcttcttct gtagtgatag aacaaataaa tgcaacgaat
     5401 actctgtctg ccctatcccg tgaagtccac actggcgtaa gagaaggccc agcagagcag
     5461 gaatctgcct agactttctc ccaatgagat cccaatatga gagggagaag agatgggcct
     5521 caggacagct gcaataccac ttgggaacac atgtggtgtc ttgatgtggc cagcgcagca
     5581 gttcagcaca acgtacctcc catctacaac agtgctggac gtgggaattc taagtcccag
     5641 tcttgagggt gggtggagat ggagggcaac aagagataca tttccagttc tccactgcag
     5701 catgcttcag tcattctgtg agtggccggg cccagggccc tcacaatttc actaccttgt
     5761 cttttacata gtcataagaa ttatcctcaa catagccttt tgacgctgta aatcttgagt
     5821 attcatttac ccttttctga tctcctggaa acagctgcct gcctgcattg cacttctctt
     5881 cccgaggagt ggggtaaatt taaaagtcaa gttatagttt ggatgttagt atagaatttt
     5941 gaaattggga attaaaaatc aggactgggg actgggagac caaaaatttc tgatcccatt
     6001 tctgatggat gtgtcacacc ttttctgtca aaataaaatg tcttggaggt tatgactcct
     6061 tggtgaaa
//
